1.1.1.209: 3(or 17)alpha-hydroxysteroid dehydrogenase

This is an abbreviated version, for detailed information about 3(or 17)alpha-hydroxysteroid dehydrogenase, go to the full flat file.

Reaction

androsterone
+
NAD(P)+
=
5alpha-androstane-3,17-dione
+
NAD(P)H
+
H+

Synonyms

3(17)alpha-hydroxysteroid dehydrogenase, AKR1C21, dehydrogenase, 3(17)alpha-hydroxy steroid, More

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase

IC50 Value

IC50 Value on EC 1.1.1.209 - 3(or 17)alpha-hydroxysteroid dehydrogenase

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0085
chrysin
Mus musculus
-
pH 7.4, 25C
0.000009
fidarestat
Mus musculus
-
pH 7.4, 25C
0.00026 - 0.0006
Hexoestrol
0.00007
minalrestat
Mus musculus
-
pH 7.4, 25C
0.029
myricetin
Mus musculus
-
pH 7.4, 25C
0.0022
quercetin
Mus musculus
-
pH 7.4, 25C
0.00015
quercitrin
Mus musculus
-
pH 7.4, 25C
0.00091
sorbinil
Mus musculus
-
pH 7.4, 25C
0.00004
Tolrestat
Mus musculus
-
pH 7.4, 25C
0.00003
zopolrestat
Mus musculus
-
pH 7.4, 25C