1.1.1.209: 3(or 17)alpha-hydroxysteroid dehydrogenase

This is an abbreviated version, for detailed information about 3(or 17)alpha-hydroxysteroid dehydrogenase, go to the full flat file.

Reaction

androsterone
+
NAD(P)+
=
5alpha-androstane-3,17-dione
+
NAD(P)H
+
H+

Synonyms

3(17)alpha-hydroxysteroid dehydrogenase, AKR1C21, dehydrogenase, 3(17)alpha-hydroxy steroid, More

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase

KCat KM Value

KCat KM Value on EC 1.1.1.209 - 3(or 17)alpha-hydroxysteroid dehydrogenase

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
3.3 - 833
4-androstene-3,17-dione
1186
20 - 417
5alpha-Androstan-17alpha-ol-3-one
5116
0.03 - 4.5
5alpha-androstan-17beta-ol-3-one
2393
1.5 - 122
5alpha-Androstan-3alpha-ol-17-one
2394
0.05 - 0.65
5alpha-androstan-3beta,17beta-diol
5504
83 - 8000
5beta-pregnane-20alpha-ol-3-one
6309
60 - 8000
5beta-pregnane-3,20-dione
2074
1 - 366
5beta-pregnane-3alpha,20alpha-diol
3128
11.67 - 500
Epitestosterone
2140
1 - 467
lithocholic acid
1325