1.1.1.209: 3(or 17)alpha-hydroxysteroid dehydrogenase

This is an abbreviated version, for detailed information about 3(or 17)alpha-hydroxysteroid dehydrogenase, go to the full flat file.

Reaction

androsterone
+
NAD(P)+
=
5alpha-androstane-3,17-dione
+
NAD(P)H
+
H+

Synonyms

3(17)alpha-hydroxysteroid dehydrogenase, AKR1C21, dehydrogenase, 3(17)alpha-hydroxy steroid, More

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase

Reaction

Reaction on EC 1.1.1.209 - 3(or 17)alpha-hydroxysteroid dehydrogenase

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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
androsterone + NAD(P)+ = 5alpha-androstane-3,17-dione + NAD(P)H + H+
show the reaction diagram
random binding pattern of substrate, ordered release of product, pro-R-hydrogen atom of NAD(P)H is transferred to the carbonyl site
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