1.1.1.19: glucuronate reductase

This is an abbreviated version, for detailed information about glucuronate reductase, go to the full flat file.

Reaction

L-gulonate
+
NADP+
=
D-glucuronate
+
NADPH
+
H+

Synonyms

AKR1A1, aldehyde reductase, aldehyde reductase II, ALR1, D-glucuronate dehydrogenase, D-glucuronate reductase, D-glucuronic reductase, hexonate dehydrogenase, L-glucuronate reductase, L-gulonate NAD-3-oxidoreductase, L-hexonate:NADP dehydrogenase, More, NADP-L-gulonate dehydrogenase, TPN l-hexonate dehydrogenase, TPN-L-gulonate dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.19 glucuronate reductase

Inhibitors

Inhibitors on EC 1.1.1.19 - glucuronate reductase

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INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2,3-Butanedione
-
-
2-mercaptoethanol
acetoacetate
Al 1576
AL-1567
alpha-ketoglutarate
Amaranth
-
-
ATP-ribose
-
competitive versus NADPH
Barbiturates
-
-
-
branched alpha-ketoacids
-
diethyldicarbonate
-
-
Diphenylhydantoin
-
-
dithiothreitol
DL-beta-hydroxybutyrate
haematin
-
-
hydroxylamine
iodoacetic acid
menadione
-
competitive versus D-glucuronate
N-ethylmaleimide
p-chloromercuribenzoate
Phenobarbital
phenolsulfophthalein
-
-
-
phenylacetate
Phenylglyoxal
-
-
ponalrestat
pyridoxal 5'-phosphate
Salicylates
-
sorbinil
Statil
-
-
Sulfobromophthalein
-
-
Tolrestat
Valproate
-
poor
Zn2+
-
-
additional information
-