1.1.1.19: glucuronate reductase

This is an abbreviated version, for detailed information about glucuronate reductase, go to the full flat file.

Reaction

L-gulonate
+
NADP+
=
D-glucuronate
+
NADPH
+
H+

Synonyms

AKR1A1, aldehyde reductase, aldehyde reductase II, ALR1, D-glucuronate dehydrogenase, D-glucuronate reductase, D-glucuronic reductase, hexonate dehydrogenase, L-glucuronate reductase, L-gulonate NAD-3-oxidoreductase, L-hexonate:NADP dehydrogenase, More, NADP-L-gulonate dehydrogenase, TPN l-hexonate dehydrogenase, TPN-L-gulonate dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.19 glucuronate reductase

KM Value

KM Value on EC 1.1.1.19 - glucuronate reductase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
500
2-deoxyglucose
-
-
0.769
2-nitrobenzaldehyde
-
-
0.526
3-Nitrobenzaldehyde
-
-
0.133 - 0.35
4-Nitrobenzaldehyde
1.05
benzaldehyde
-
-
139.9
D-arabinose
-
-
333
D-galactose
-
-
333
D-glucose
-
-
0.0543 - 9.1
D-glucuronate
0.69
D-glucuronolactone
-
-
4.8
D-glyceraldehyde
-
-
333
D-ribose
-
-
333
D-xylose
-
-
1.671
DL-glyceraldehyde
-
-
0.00045 - 0.0025
gamma-hydroxybutyrate
2.1 - 7.6
L-gulonate
0.0014 - 0.02
NADP+
0.009 - 0.036
NADPH
2.6
Pyridine-3-aldehyde
-
-