1.1.1.153: sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)

This is an abbreviated version, for detailed information about sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming), go to the full flat file.

Reaction

L-erythro-7,8-dihydrobiopterin
+
NADP+
=
sepiapterin
+
NADPH
+
H+

Synonyms

AKR1B1, reductase, sepiapterin, sepiapterin reductase, SPR, SR

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)

Turnover Number

Turnover Number on EC 1.1.1.153 - sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.627
1,2-naphthoquinone
Homo sapiens
-
wild-type, pH 6.4, 37C
0.45
1,4-Naphthoquinone
Homo sapiens
-
wild-type, pH 6.4, 37C
1.43
2,3-dimethoxynaphthalene-1,4-dione
Homo sapiens
-
wild-type, pH 6.4, 37C
0.0048 - 0.805
9,10-phenanthrenequinone
1.45
menadione
Homo sapiens
-
wild-type, pH 6.4, 37C
0.0053 - 1.61
sepiapterin