1.1.1.153: sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)

This is an abbreviated version, for detailed information about sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming), go to the full flat file.

Reaction

L-erythro-7,8-dihydrobiopterin
+
NADP+
=
sepiapterin
+
NADPH
+
H+

Synonyms

AKR1B1, reductase, sepiapterin, sepiapterin reductase, SPR, SR

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)

KI Value

KI Value on EC 1.1.1.153 - sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
3.1 - 3.4
1-norepinephrine
0.0009
benzoquinone
-
wild-type, pH 6.7, 37C
0.0027
indomethacin
-
wild-type, pH 6.7, 37C
0.025 - 0.03
Melatonin
0.00017 - 0.0002
N-acetyl-serotonin
0.0009
N-acetylserotonin
-
wild-type, pH 6.7, 37C
0.0005
phenylquinone
-
wild-type, pH 6.7, 37C
2.3 - 2.5
serotonin