1.1.1.153: sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
This is an abbreviated version!
For detailed information about sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming), go to the full flat file.
Word Map on EC 1.1.1.153
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1.1.1.153
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tetrahydrobiopterin
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bh4
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aldo-keto
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cyclohydrolase
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aldose
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neurotransmitter
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pterins
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dopa-responsive
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tetrahydropterins
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6-pyruvoyl-tetrahydropterin
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n-acetylserotonin
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dystonia
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dihydropteridine
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dihydroneopterin
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6-pyruvoyl
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pteridine
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neopterin
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gtpch
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ptges
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gtp-cyclohydrolase
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5-hydroxytryptophan
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akr1b3
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6r-5,6,7,8-tetrahydrobiopterin
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epalrestat
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hyperphenylalaninaemia
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segawa
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2,4-diamino-6-hydroxypyrimidine
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medicine
- 1.1.1.153
- tetrahydrobiopterin
- bh4
-
aldo-keto
-
cyclohydrolase
- aldose
-
neurotransmitter
- pterins
-
dopa-responsive
- tetrahydropterins
- 6-pyruvoyl-tetrahydropterin
- n-acetylserotonin
- dystonia
- dihydropteridine
- dihydroneopterin
-
6-pyruvoyl
- pteridine
- neopterin
- gtpch
- ptges
-
gtp-cyclohydrolase
- 5-hydroxytryptophan
- akr1b3
- 6r-5,6,7,8-tetrahydrobiopterin
- epalrestat
- hyperphenylalaninaemia
-
segawa
- 2,4-diamino-6-hydroxypyrimidine
- medicine
Reaction
Synonyms
AKR1B1, MDSPI16 protein, MDSPR, reductase, sepiapterin, sepiapterin reductase, SPR, SR
ECTree
1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)Advanced search results
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results (Purification
Purification on EC 1.1.1.153 - sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
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PURIFICATION (Commentary) 
ORGANISM
UNIPROT
LITERATURE
liver
native enzyme 5000fold from liver by ammonium sulfate and protamine sulfate fractionation, and two times treatment by hydroxylapatite and anion exchange chromatography
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native enzyme from erythrocytes by hydroxylapatite and NADP+-affinity chromatography, to homogeneity
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native enzyme partially from brain by ammonium sulfate fractionation and hydroxylapatite chromatography, and from erythrocytes to homogeneity by affinity chromatography and isoelectric focusing
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Ni-NTA bead chromatography, MonoQ column chromatography, and Superdex 200 gel filtration
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recombinant His-tagged enzyme from Escherichia coli strain BL21(DE3)
recombinant His-tagged native and selenomethionine-labeled enzyme from Escherichia coli strain BL21(DE3) by nickel affinity and anion exchange chromatography, followed by gel filtration
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recombinant protein using His-tag
