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Information on EC 3.5.1.104 - peptidoglycan-N-acetylglucosamine deacetylase

for references in articles please use BRENDA:EC3.5.1.104
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IUBMB Comments
Modification of peptidoglycan by N-deacetylation is an important factor in virulence of Helicobacter pylori, Listeria monocytogenes and Streptococcus suis [4-6]. The enzyme from Streptococcus pneumoniae is a metalloenzyme using a His-His-Asp zinc-binding triad with a nearby aspartic acid and histidine acting as the catalytic base and acid, respectively .
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The enzyme appears in viruses and cellular organisms
Synonyms
peptidoglycan deacetylase, hp310, sfpgda, peptidoglycan n-acetylglucosamine deacetylase, sppgda, bc1960, glcnac deacetylase, ba1977, bc3618, hppgda, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
peptidoglycan-N-acetyl-D-glucosamine + H2O = peptidoglycan-D-glucosamine + acetate
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