EC Number |
Metals/Ions |
Reference |
---|
3.5.1.104 | Ca2+ |
activates |
730006 |
3.5.1.104 | Co2+ |
0.05 mM, 30fold increase in activity |
689736 |
3.5.1.104 | Co2+ |
1 mM, 10% increase in activity |
687500 |
3.5.1.104 | Co2+ |
activates, best metal ion |
733581 |
3.5.1.104 | Fe2+ |
abolishes the acnB-pgdA transcript binding leading to destabilization of the enzyme's mRNA |
729936 |
3.5.1.104 | Mg2+ |
activates |
730006 |
3.5.1.104 | Mn2+ |
best activating metal ion |
730006 |
3.5.1.104 | more |
metal site models show an intrinsic preference for zinc, but also significant flexibility of the site so that binding of other ions can eventually occur, e.g. Fe2+, Co2+, Cu2+, Mg2+, quantum chemical calculations, overview |
730914 |
3.5.1.104 | more |
metallo-dependent enzyme |
733581 |
3.5.1.104 | more |
SpPgdA is a metalloenzyme using a His-His-Asp zinc-binding triad with a nearby aspartic acid and histidine acting as the catalytic base and acid, respectively |
689736 |