Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
1D-myo-inositol 1,4,5-triphosphate + diacylglycerol
-
-
-
-
?
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
phosphatidylinositol + H2O
?
phosphatidylinositol 4,5-bisphosphate + H2O
D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
additional information
?
-
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
-
-
-
?
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
-
-
-
?
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
-
-
-
?
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
-
-
-
-
?
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
-
-
-
?
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
-
-
-
?
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
-
-
-
?
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
-
-
-
?
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
-
-
products are two second messengers
-
?
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
domain structure of PLCdelta1
-
?
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
domain structure of PLCzeta
-
?
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
-
PLCbeta1 is involved in nuclear inositol lipid signaling
-
?
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
sperm-specific PLCzeta induces intracellular Ca2+ oscillations and subsequent early embryonic development when expressed in mouse eggs, PLCzeta may be the physiological mammalian egg-activating sperm factor
-
?
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
PI-PLC beta1 is essential in the IGF-1 mitogenic signaling pathway
-
-
?
phosphatidylinositol + H2O
?
-
-
-
-
?
phosphatidylinositol + H2O
?
-
at neutral pH and low Ca2+ concentration the membrane bound enzyme hydrolyzes phosphatidylinositol 4,5-diphosphate in preference to phosphatidylinositol
-
-
?
phosphatidylinositol 4,5-bisphosphate + H2O
D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
-
-
-
?
phosphatidylinositol 4,5-bisphosphate + H2O
D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
-
membrane-bound enzyme hydrolyzes phosphatidylinositol 4,5-diphosphate in preference to phosphatidylinositol
-
?
additional information
?
-
absolute requirement for PLC-gamma1 in villin-induced cell migration
-
-
?
additional information
?
-
-
the activation of the gamma1 isoenzyme is a biologically important event in zona pellucida-stimulated inositol phospholipid metabolism with a potential role in signal transduction leading to acrosomal exocytosis
-
-
?
additional information
?
-
-
PLC delta1 is required for skin stem cell lineage commitment
-
?
additional information
?
-
-
PLC-beta1 is nessecary for the development and/or maintenance of brain inhibitory pathways, the retinal variants of PLC-beta4 function in signal processing within the retina, PLC-beta3 plays a role in the early development
-
?
additional information
?
-
-
phospholipase C epsilon modulates beta-adrenergic receptor-dependent cardiac contraction and inhibits cardiac hypertrophy
-
-
?
additional information
?
-
-
PLC-eta enzymes may function in the membrane-mediated signaling cascade through intracellular Ca2+ and protein kinase C pathways
-
-
?
additional information
?
-
PLC-eta may perform fundamental roles in the brain
-
-
?
additional information
?
-
-
PLC-eta may perform fundamental roles in the brain
-
-
?
additional information
?
-
-
PLCgamma2 is crucial for development of the NL cell receptor repertoire and signaling of activating NK cell receptors, mediating optimal NL cell function in vivo
-
-
?
additional information
?
-
-
recombinant PLCzeta protein induces Ca2+ oscillations in mouse eggs
-
-
?
additional information
?
-
recombinant PLCzeta protein induces Ca2+ oscillations in mouse eggs
-
-
?
additional information
?
-
recombinant PLCzeta protein induces Ca2+ oscillations in mouse eggs
-
-
?
additional information
?
-
-
signaling of myelin phagocytosis mediated by complement-receptor-3 alone and by complement-receptor-3 combined with scavenger-receptor-AI/II involves phosphatidylinositol 3-kinase, phosphoinositide-specific phospholipase-Cgamma and protein kinase-C, the cascade phosphatidylinositol 3-kinase -> phosphoinositide-specific phospholipase-Cgamma -> protein kinase-C, and wide range modulation by protein kinase-C
-
-
?
additional information
?
-
the neuron-specific enzyme may be important for the formation and/or maintenance of the neuronal network in the postnatal brain
-
-
?
additional information
?
-
-
inhibition of phosphatidylinositol 3-kinase may go through phosphoinositide-specific phospholipase C pathway leading to increase of expression of the inducible nitric oxide synthase, indicating that phosphatidylinositol 3-kinase and phosphoinositide-specific phospholipase C may counteract to regulate the metabolism of phosphatidylinositol (4,5)-bisphosphate depending on cell types or their conditions
-
-
?
additional information
?
-
overview: role of nuclear PI-PLCbeta1 in cell proliferation and differentiation
-
-
?
additional information
?
-
PLCepsilon is required for thrombin- but not lysophosphatidic acid-induced sustained ERK activation and DNA synthesis, providing a novel mechanism for G protein-coupled receptor and Rho signaling to cell proliferation. PLCepsilon has a role as a guanine nucleotide exchange factor for Rap1
-
-
?
additional information
?
-
PLCgamma2 is essential for RANK (Receptor activator of NF-kB) signaling, and its deficiency leads to defective lymph node organogenesis and osteoclast differentiation
-
-
?
additional information
?
-
-
PLCepsilon exhibits activity as RasGEF toward Rap1, but not to Ras, Rap2A or Rho
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
1D-myo-inositol 1,4,5-triphosphate + diacylglycerol
-
-
-
-
?
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
additional information
?
-
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
-
-
-
-
?
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
-
-
products are two second messengers
-
?
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
-
PLCbeta1 is involved in nuclear inositol lipid signaling
-
?
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
sperm-specific PLCzeta induces intracellular Ca2+ oscillations and subsequent early embryonic development when expressed in mouse eggs, PLCzeta may be the physiological mammalian egg-activating sperm factor
-
?
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
PI-PLC beta1 is essential in the IGF-1 mitogenic signaling pathway
-
-
?
additional information
?
-
absolute requirement for PLC-gamma1 in villin-induced cell migration
-
-
?
additional information
?
-
-
the activation of the gamma1 isoenzyme is a biologically important event in zona pellucida-stimulated inositol phospholipid metabolism with a potential role in signal transduction leading to acrosomal exocytosis
-
-
?
additional information
?
-
-
PLC delta1 is required for skin stem cell lineage commitment
-
?
additional information
?
-
-
PLC-beta1 is nessecary for the development and/or maintenance of brain inhibitory pathways, the retinal variants of PLC-beta4 function in signal processing within the retina, PLC-beta3 plays a role in the early development
-
?
additional information
?
-
-
phospholipase C epsilon modulates beta-adrenergic receptor-dependent cardiac contraction and inhibits cardiac hypertrophy
-
-
?
additional information
?
-
-
PLC-eta enzymes may function in the membrane-mediated signaling cascade through intracellular Ca2+ and protein kinase C pathways
-
-
?
additional information
?
-
PLC-eta may perform fundamental roles in the brain
-
-
?
additional information
?
-
-
PLC-eta may perform fundamental roles in the brain
-
-
?
additional information
?
-
-
PLCgamma2 is crucial for development of the NL cell receptor repertoire and signaling of activating NK cell receptors, mediating optimal NL cell function in vivo
-
-
?
additional information
?
-
-
recombinant PLCzeta protein induces Ca2+ oscillations in mouse eggs
-
-
?
additional information
?
-
recombinant PLCzeta protein induces Ca2+ oscillations in mouse eggs
-
-
?
additional information
?
-
recombinant PLCzeta protein induces Ca2+ oscillations in mouse eggs
-
-
?
additional information
?
-
-
signaling of myelin phagocytosis mediated by complement-receptor-3 alone and by complement-receptor-3 combined with scavenger-receptor-AI/II involves phosphatidylinositol 3-kinase, phosphoinositide-specific phospholipase-Cgamma and protein kinase-C, the cascade phosphatidylinositol 3-kinase -> phosphoinositide-specific phospholipase-Cgamma -> protein kinase-C, and wide range modulation by protein kinase-C
-
-
?
additional information
?
-
the neuron-specific enzyme may be important for the formation and/or maintenance of the neuronal network in the postnatal brain
-
-
?
additional information
?
-
-
inhibition of phosphatidylinositol 3-kinase may go through phosphoinositide-specific phospholipase C pathway leading to increase of expression of the inducible nitric oxide synthase, indicating that phosphatidylinositol 3-kinase and phosphoinositide-specific phospholipase C may counteract to regulate the metabolism of phosphatidylinositol (4,5)-bisphosphate depending on cell types or their conditions
-
-
?
additional information
?
-
overview: role of nuclear PI-PLCbeta1 in cell proliferation and differentiation
-
-
?
additional information
?
-
PLCepsilon is required for thrombin- but not lysophosphatidic acid-induced sustained ERK activation and DNA synthesis, providing a novel mechanism for G protein-coupled receptor and Rho signaling to cell proliferation. PLCepsilon has a role as a guanine nucleotide exchange factor for Rap1
-
-
?
additional information
?
-
PLCgamma2 is essential for RANK (Receptor activator of NF-kB) signaling, and its deficiency leads to defective lymph node organogenesis and osteoclast differentiation
-
-
?
additional information
?
-
-
PLCepsilon exhibits activity as RasGEF toward Rap1, but not to Ras, Rap2A or Rho
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Wang, P.; Toyoshima, S.; Osawa, T.
Partial purification and characterization of membrane-bound and cytosolic phosphatidylinositol-specific phospholipases C from murine thymocytes
J. Biochem.
100
1015-1022
1986
Mus musculus
brenda
Tomes, C.N.; McMaster, C.R.; Saling, P.M.
Activation of mouse sperm phosphatidylinositol-4,5-bisphosphate-phospholipase C by zona pellucida is modulated by tyrosine phosphorylation
Mol. Reprod. Dev.
43
196-204
1996
Mus musculus
brenda
Shute, J.K.; Smith, M.E.
Phosphatidylinositol phosphodiesterase in isolated plasma membranes of rodent skeletal muscle
Biochem. Soc. Trans.
13
193-194
1985
Mus musculus, Mus musculus C57BL, Rattus norvegicus, Rattus norvegicus Sprague-Dawley
-
brenda
Ochocka, A.M.; Pawelczyk, T.
Isozymes delta of phosphoinositide-specific phospholipase C and their role in signal transduction in the cell
Acta Biochim. Pol.
50
1097-1110
2003
Bos taurus, Homo sapiens, Mus musculus, Rattus norvegicus
brenda
Cocco, L.; Martelli, A.M.; Mazzotti, G.; Barnabei, O.; Manzoli, F.A.
Inositides and the nucleus: phospholipase Cbeta family localization and signaling activity
Adv. Enzyme Regul.
40
83-95
2000
Mus musculus
brenda
Kouchi, Z.; Fukami, K.; Shikano, T.; Oda, S.; Nakamura, Y.; Takenawa, T.; Miyazaki, S.
Recombinant phospholipase Czeta has high Ca2+ sensitivity and induces Ca2+ oscillations in mouse eggs
J. Biol. Chem.
279
10408-10412
2004
Mus musculus, Mus musculus (Q8K4D7), Mus musculus (Q8R3B1)
brenda
Rebecchi, M.J.; Pentyala, S.N.
Structure, function, and control of phosphoinositide-specific phospholipase C
Physiol. Rev.
80
1291-1335
2000
Arabidopsis thaliana, Saccharomyces cerevisiae, Dictyostelium discoideum, Drosophila sp. (in: flies), Homo sapiens, Mus musculus, Rattus norvegicus, Saccharomyces cerevisiae PLC1p
brenda
Hwang, J.I.; Oh, Y.S.; Shin, K.J.; Kim, H.; Ryu, S.H.; Suh, P.G.
Molecular cloning and characterization of a novel phospholipase C, PLC-eta
Biochem. J.
389
181-186
2005
Mus musculus (Q4KWH5), Mus musculus, Homo sapiens (Q4KWH8), Homo sapiens
brenda
Wang, H.; Oestreich, E.A.; Maekawa, N.; Bullard, T.A.; Vikstrom, K.L.; Dirksen, R.T.; Kelley, G.G.; Blaxall, B.C.; Smrcka, A.V.
Phospholipase C epsilon modulates beta-adrenergic receptor-dependent cardiac contraction and inhibits cardiac hypertrophy
Circ. Res.
97
1305-1313
2005
Mus musculus
brenda
Martelli, A.M.; Fiume, R.; Faenza, I.; Tabellini, G.; Evangelista, C.; Bortul, R.; Follo, M.Y.; Fala, F.; Cocco, L.
Nuclear phosphoinositide specific phospholipase C (PI-PLC)-beta 1: a central intermediary in nuclear lipid-dependent signal transduction
Histol. Histopathol.
20
1251-1260
2005
Cricetulus griseus, Homo sapiens, Mus musculus, Rattus norvegicus
brenda
Stewart, A.J.; Mukherjee, J.; Roberts, S.J.; Lester, D.; Farquharson, C.
Identification of a novel class of mammalian phosphoinositol-specific phospholipase C enzymes
Int. J. Mol. Med.
15
117-121
2005
Homo sapiens, Mus musculus
brenda
Nakahara, M.; Shimozawa, M.; Nakamura, Y.; Irino, Y.; Morita, M.; Kudo, Y.; Fukami, K.
A novel phospholipase C, PLC(eta)2, is a neuron-specific isozyme
J. Biol. Chem.
280
29128-29134
2005
Mus musculus (A2AP18)
brenda
Tassi, I.; Presti, R.; Kim, S.; Yokoyama, W.M.; Gilfillan, S.; Colonna, M.
Phospholipase C-gamma2 is a critical signaling mediator for murine NK cell activating receptors
J. Immunol.
175
749-754
2005
Mus musculus
brenda
Kim, Y.J.; Sekiya, F.; Poulin, B.; Bae, Y.S.; Rhee, S.G.
Mechanism of B-cell receptor-induced phosphorylation and activation of phospholipase C-gamma2
Mol. Cell. Biol.
24
9986-9999
2004
Homo sapiens, Homo sapiens (P16885), Mus musculus, Mus musculus (Q8CIH5)
brenda
Makranz, C.; Cohen, G.; Baron, A.; Levidor, L.; Kodama, T.; Reichert, F.; Rotshenker, S.
Phosphatidylinositol 3-kinase, phosphoinositide-specific phospholipase-Cgamma and protein kinase-C signal myelin phagocytosis mediated by complement receptor-3 alone and combined with scavenger receptor-AI/II in macrophages
Neurobiol. Dis.
15
279-286
2004
Mus musculus
brenda
Wang, Y.; Tomar, A.; George, S.P.; Khurana, S.
Obligatory role for phospholipase C-gamma 1 in villin-induced epithelial cell migration
Am. J. Physiol.
292
C1775-C1786
2007
Mus musculus (Q62077)
brenda
Cocco, L.; Faenza, I.; Fiume, R.; Billi, A.M.; Gilmour, R.S.; Manzoli, F.A.
Phosphoinositide-specific phospholipase C (PI-PLC) beta 1 and nuclear lipid-dependent signaling
Biochim. Biophys. Acta
1761
509-521
2006
Rattus norvegicus (P10687), Mus musculus (Q9Z1B3)
brenda
Yagisawa, H.; Okada, M.; Naito, Y.; Sasaki, K.; Yamaga, M.; Fujii, M.
Coordinated intracellular translocation of phosphoinositide-specific phospholipase C-delta with the cell cycle
Biochim. Biophys. Acta
1761
522-534
2006
Mus musculus (Q8R3B1)
brenda
Liu, D.; Liang, H.; Chen, C.; Lin, S.; Zhong, W.; Ho, F.; Hou, W.; Lo, J.; Ho, Y.; Lin, P.; Hung, L.; Liang, Y.
Switch activation of PI-PLC downstream signals in activated macrophages with wortmannin
Biochim. Biophys. Acta
1773
869-879
2007
Mus musculus
brenda
Lefevre, B.; Pesty, A.; Courtot, A.M.; Martins, C.V.; Broca, O.; Denys, A.; Arnault, E.; Poirot, C.; Avazeri, N.
The phosphoinositide-phospholipase C (PI-PLC) pathway in the mouse oocyte
Crit. Rev. Eukaryot. Gene Expr.
17
259-269
2007
Mus musculus (Q9Z1B3), Mus musculus
brenda
Faenza, I.; Bregoli, L.; Ramazzotti, G.; Gaboardi, G.; Follo, M.Y.; Mongiorgi, S.; Billi, A.M.; Manzoli, L.; Martelli, A.M.; Cocco, L.
Nuclear phospholipase C beta1 and cellular differentiation
Front. Biosci.
13
2452-2463
2008
Homo sapiens (Q01970), Homo sapiens (Q9NQ66), Mus musculus (Q9Z1B3)
brenda
Nomikos, M.; Mulgrew-Nesbitt, A.; Pallavi, P.; Mihalyne, G.; Zaitseva, I.; Swann, K.; Lai, F.A.; Murray, D.; McLaughlin, S.
Binding of phosphoinositide-specific phospholipase C-zeta (PLC-zeta) to phospholipid membranes: potential role of an unstructured cluster of basic residues
J. Biol. Chem.
282
16644-16653
2007
Mus musculus
brenda
Nam, J.H.; Lee, H.; Nguyen, Y.H.; Kang, T.M.; Lee, S.W.; Kim, H.; Kim, S.J.; Earm, Y.E.; Kim, S.J.
Mechanosensitive activation of K+ channel via phospholipase C-induced depletion of phosphatidylinositol 4,5-bisphosphate in B lymphocytes
J. Physiol.
582
977-990
2006
Mus musculus
brenda
Citro, S.; Malik, S.; Oestreich, E.A.; Radeff-Huang, J.; Kelley, G.G.; Smrcka, A.V.; Brown, J.H.
Phospholipase Cepsilon is a nexus for Rho and Rap-mediated G protein-coupled receptor-induced astrocyte proliferation
Proc. Natl. Acad. Sci. USA
104
15543-15548
2007
Mus musculus (Q8K4S1)
brenda
Ho, K.K.; Mann, D.J.
Nuclear signaling through phospholipase C and phosphatidylinositol 4,5-bisphosphate
Signal Transduction
6
92-100
2006
Homo sapiens, Mus musculus (Q8R3B1), Mus musculus (Q9Z1B3)
-
brenda
Ichise, H.; Ichise, T.; Ohtani, O.; Yoshida, N.
Phospholipase Cgamma2 is necessary for separation of blood and lymphatic vasculature in mice
Development
136
191-195
2009
Mus musculus (Q8CIH5), Mus musculus
brenda
Frei, E.; Hofmann, F.; Wegener, J.W.
Phospholipase C mediated Ca(2+) signals in murine urinary bladder smooth muscle
Eur. J. Pharmacol.
610
106-109
2009
Mus musculus
brenda
Chen, Y.; Wang, X.; Di, L.; Fu, G.; Chen, Y.; Bai, L.; Liu, J.; Feng, X.; McDonald, J.M.; Michalek, S.; He, Y.; Yu, M.; Fu, Y.X.; Wen, R.; Wu, H.; Wang, D.
Phospholipase Cgamma2 mediates RANKL-stimulated lymph node organogenesis and osteoclastogenesis
J. Biol. Chem.
283
29593-29601
2008
Mus musculus (Q8CIH5)
brenda
Xu, S.; Huo, J.; Lee, K.G.; Kurosaki, T.; Lam, K.P.
Phospholipase C{gamma}2 is critical for dectin-1-mediated Ca2+ flux and cytokine production in dendritic cells
J. Biol. Chem.
284
7038-7046
2009
Mus musculus, Mus musculus C57BL/6
brenda
Lee, J.S.; Yoo, H.; Suh, Y.G.; Jung, J.K.; Kim, J.
Structure-activity relationship of pentacylic triterpene esters from Uncaria rhynchophylla as inhibitors of phospholipase Cgamma1
Planta Med.
74
1481-1487
2008
Homo sapiens, Mus musculus
brenda
Fiume, R.; Teti, G.; Faenza, I.; Cocco, L.
Phosphoinositide-specific phospholipase C beta1 signal transduction in the nucleus
Methods Mol. Biol.
645
143-164
2010
Rattus norvegicus (P10687), Homo sapiens (Q9NQ66), Homo sapiens, Mus musculus (Q9Z1B3)
brenda
Fukami, K.; Inanobe, S.; Kanemaru, K.; Nakamura, Y.
Phospholipase C is a key enzyme regulating intracellular calcium and modulating the phosphoinositide balance
Prog. Lipid Res.
49
429-437
2010
Homo sapiens, Mus musculus, Rattus norvegicus
brenda
Kim, H.S.; Park, M.Y.; Lee, S.K.; Park, J.S.; Lee, H.Y.; Bae, Y.S.
Activation of formyl peptide receptor 2 by WKYMVm enhances emergency granulopoiesis through phospholipase C activity
BMB Rep.
51
418-423
2018
Mus musculus
brenda
Jones, K.
Mammalian sperm contain two factors for calcium release and egg activation Phospholipase C zeta and a cryptic activating factor
Mol. Hum. Reprod.
24
465-468
2018
Mus musculus
brenda
Beziau, D.M.; Toussaint, F.; Blanchette, A.; Dayeh, N.R.; Charbel, C.; Tardif, J.C.; Dupuis, J.; Ledoux, J.
Expression of phosphoinositide-specific phospholipase C isoforms in native endothelial cells
PLoS ONE
10
e0123769
2015
Mus musculus
brenda