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Literature summary for 3.1.4.11 extracted from

  • Tomes, C.N.; McMaster, C.R.; Saling, P.M.
    Activation of mouse sperm phosphatidylinositol-4,5-bisphosphate-phospholipase C by zona pellucida is modulated by tyrosine phosphorylation (1996), Mol. Reprod. Dev., 43, 196-204.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus the activation of the gamma1 isoenzyme is a biologically important event in zona pellucida-stimulated inositol phospholipid metabolism with a potential role in signal transduction leading to acrosomal exocytosis ?
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?

Organism

Organism UniProt Comment Textmining
Mus musculus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
semen the gamma1 isoenzyme is restricted to the sperm head Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the activation of the gamma1 isoenzyme is a biologically important event in zona pellucida-stimulated inositol phospholipid metabolism with a potential role in signal transduction leading to acrosomal exocytosis Mus musculus ?
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?
phosphatidylinositol 4,5-bisphosphate + H2O
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Mus musculus D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
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?