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Synonyms
phosphotransacetylase, phosphate acetyltransferase, pta-1, pta-2, aywb-pdul, pdul1, pdul2, moth_0864, moth_1181, phosphotransacetylase pta,
more
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acetyl-CoA + phosphate = CoA + acetyl phosphate
acetyl-CoA + phosphate = CoA + acetyl phosphate

reaction mechanism
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acetyl-CoA + phosphate = CoA + acetyl phosphate
evidence against an acyl-enzyme intermediate
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acetyl-CoA + phosphate = CoA + acetyl phosphate
rapid equilibrium random bi-bi reaction mechanism
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acetyl-CoA + phosphate = CoA + acetyl phosphate
rapid equilibrium random bi-bi reaction mechanism
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acetyl-CoA + phosphate = CoA + acetyl phosphate
ternary complex kinetic echanism rather than a ping-pong kinetic mechanism. Sustrates bind to the enzyme in a random order
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acetyl-CoA + phosphate = CoA + acetyl phosphate
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3'-dephospho-CoA + acetyl phosphate
acetyl-3'-dephospho-CoA + phosphate
acetyl phosphate + CoA
acetyl-CoA + phosphate
acetyl-CoA + arsenate
CoA + acetyl arsenate
acetyl-CoA + carnitine
CoA + O-acetylcarnitine
acetyl-CoA + phosphate
acetyl Phosphate + CoA
acetyl-CoA + phosphate
CoA + acetyl phosphate
acetyl-phosphate + CoA
acetyl-CoA + phosphate
arsenate + acetyl-CoA
acetyl arsenate + CoA
butyryl-CoA + phosphate
CoA + butyryl phosphate
CoA + acetyl phosphate
acetyl-CoA + phosphate
propionyl-CoA + phosphate
CoA + propionyl phosphate
additional information
?
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3'-dephospho-CoA + acetyl phosphate

acetyl-3'-dephospho-CoA + phosphate
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rate is about one tenth of the activity with CoA
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?
3'-dephospho-CoA + acetyl phosphate
acetyl-3'-dephospho-CoA + phosphate
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rate is about one tenth of the activity with CoA
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?
acetyl phosphate + CoA

acetyl-CoA + phosphate
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acetyl phosphate + CoA
acetyl-CoA + phosphate
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?
acetyl phosphate + CoA
acetyl-CoA + phosphate
with isoform Pta-2, reaction is irreversible, no acetyl phosphate forming reaction can be detected
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r
acetyl phosphate + CoA
acetyl-CoA + phosphate
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r
acetyl phosphate + CoA
acetyl-CoA + phosphate
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r
acetyl-CoA + arsenate

CoA + acetyl arsenate
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?
acetyl-CoA + arsenate
CoA + acetyl arsenate
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?
acetyl-CoA + carnitine

CoA + O-acetylcarnitine
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?
acetyl-CoA + carnitine
CoA + O-acetylcarnitine
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?
acetyl-CoA + phosphate

acetyl Phosphate + CoA
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?
acetyl-CoA + phosphate
acetyl Phosphate + CoA
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?
acetyl-CoA + phosphate
acetyl Phosphate + CoA
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r
acetyl-CoA + phosphate
acetyl Phosphate + CoA
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r
acetyl-CoA + phosphate

CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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formation of acetyl-CoA is favored
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acetyl-CoA + phosphate
CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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in reverse reaction specific for CoA
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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in reverse reaction specific for CoA
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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ir
acetyl-CoA + phosphate
CoA + acetyl phosphate
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ir
acetyl-CoA + phosphate
CoA + acetyl phosphate
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ir
acetyl-CoA + phosphate
CoA + acetyl phosphate
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ir
acetyl-CoA + phosphate
CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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acetyl-CoA + phosphate
CoA + acetyl phosphate
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rate of acetyl-CoA synthesis is 10times greater than rate of acetyl phosphate synthesis
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acetyl-CoA + phosphate
CoA + acetyl phosphate
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integral role in acetate metabolism
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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ir
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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enables growth on acetate as carbon and energy source, required for ethanolamine catabolism
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
acetate excretion during growth of Salmonella enterica on ethanolamine requires phosphotransacetylase (EutD) activity, and acetate recapture requires acetyl-CoA synthetase (Acs) and phosphotransacetylase (Pta) activities
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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rate of acetyl-CoA synthesis is 6.5times greater than rate of acetyl phosphate synthesis
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r
acetyl-phosphate + CoA

acetyl-CoA + phosphate
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?
acetyl-phosphate + CoA
acetyl-CoA + phosphate
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ternary complex kinetic echanism rather than a ping-pong kinetic mechanism. Sustrates bind to the enzyme in a random order
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r
arsenate + acetyl-CoA

acetyl arsenate + CoA
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?
arsenate + acetyl-CoA
acetyl arsenate + CoA
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?
arsenate + acetyl-CoA
acetyl arsenate + CoA
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?
butyryl-CoA + phosphate

CoA + butyryl phosphate
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?
butyryl-CoA + phosphate
CoA + butyryl phosphate
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at a rate 0.01 as rapid as acetyl-CoA
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butyryl-CoA + phosphate
CoA + butyryl phosphate
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?
CoA + acetyl phosphate

acetyl-CoA + phosphate
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r
CoA + acetyl phosphate
acetyl-CoA + phosphate
involved in taurine catabolism
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?
CoA + acetyl phosphate
acetyl-CoA + phosphate
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r
CoA + acetyl phosphate
acetyl-CoA + phosphate
acetate excretion during growth of Salmonella enterica on ethanolamine requires phosphotransacetylase (EutD) activity, and acetate recapture requires acetyl-CoA synthetase (Acs) and phosphotransacetylase (Pta) activities
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?
propionyl-CoA + phosphate

CoA + propionyl phosphate
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?
propionyl-CoA + phosphate
CoA + propionyl phosphate
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at a rate 0.1 to 0.5 as rapid as acetyl-CoA
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?
propionyl-CoA + phosphate
CoA + propionyl phosphate
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propionyl-CoA + phosphate
CoA + propionyl phosphate
reaction of EC 2.3.1.222
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?
propionyl-CoA + phosphate
CoA + propionyl phosphate
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?
additional information

?
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enzymes is confirmed by total proteome analysis of glycerol-grown cells
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?
additional information
?
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physiological function in anaerobic metabolism of eukaryotic green algae rather than in aerobic acetate activation
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?
additional information
?
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arsenolysis
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?
additional information
?
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arsenolysis
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?
additional information
?
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enzyme additionally catalyzes reaction with propionyl-CoA, reaction of EC 2.3.1.222, and with butanoyl-CoA, reaction of EC 2.3.1.19
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additional information
?
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enzyme additionally catalyzes reaction with propionyl-CoA, reaction of EC 2.3.1.222, and with butanoyl-CoA, reaction of EC 2.3.1.19
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additional information
?
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enzyme additionally catalyzes reaction with propionyl-CoA, reaction of EC 2.3.1.222, and with butanoyl-CoA, reaction of EC 2.3.1.19
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additional information
?
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no substrates: butanoyl-CoA, acetyl phosphate
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additional information
?
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no substrates: butanoyl-CoA, acetyl phosphate
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additional information
?
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no substrates: butanoyl-CoA, acetyl phosphate
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additional information
?
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mutation of phosphotransacetylase reduces the virulence of Salmonella enterica serovar typhimurium in mice
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?
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acetyl-CoA + phosphate
CoA + acetyl phosphate
CoA + acetyl phosphate
acetyl-CoA + phosphate
additional information
?
-
acetyl-CoA + phosphate

CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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ir
acetyl-CoA + phosphate
CoA + acetyl phosphate
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ir
acetyl-CoA + phosphate
CoA + acetyl phosphate
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-
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ir
acetyl-CoA + phosphate
CoA + acetyl phosphate
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-
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ir
acetyl-CoA + phosphate
CoA + acetyl phosphate
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-
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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-
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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-
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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-
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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-
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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-
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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-
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
integral role in acetate metabolism
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-
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
-
-
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
-
-
-
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
-
-
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
enables growth on acetate as carbon and energy source, required for ethanolamine catabolism
-
-
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
acetate excretion during growth of Salmonella enterica on ethanolamine requires phosphotransacetylase (EutD) activity, and acetate recapture requires acetyl-CoA synthetase (Acs) and phosphotransacetylase (Pta) activities
-
-
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
-
-
-
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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r
acetyl-CoA + phosphate
CoA + acetyl phosphate
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-
-
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
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-
-
r
CoA + acetyl phosphate

acetyl-CoA + phosphate
involved in taurine catabolism
-
-
?
CoA + acetyl phosphate
acetyl-CoA + phosphate
acetate excretion during growth of Salmonella enterica on ethanolamine requires phosphotransacetylase (EutD) activity, and acetate recapture requires acetyl-CoA synthetase (Acs) and phosphotransacetylase (Pta) activities
-
-
?
additional information

?
-
-
physiological function in anaerobic metabolism of eukaryotic green algae rather than in aerobic acetate activation
-
-
?
additional information
?
-
-
mutation of phosphotransacetylase reduces the virulence of Salmonella enterica serovar typhimurium in mice
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.