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3'-dephospho-CoA + acetyl phosphate
acetyl-3'-dephospho-CoA + phosphate
acetyl phosphate + CoA
acetyl-CoA + phosphate
acetyl-CoA + arsenate
CoA + acetyl arsenate
acetyl-CoA + carnitine
CoA + O-acetylcarnitine
acetyl-CoA + phosphate
acetyl Phosphate + CoA
acetyl-CoA + phosphate
CoA + acetyl phosphate
acetyl-phosphate + CoA
acetyl-CoA + phosphate
arsenate + acetyl-CoA
acetyl arsenate + CoA
-
Substrates: -
Products: -
?
butyryl-CoA + phosphate
CoA + butyryl phosphate
CoA + acetyl phosphate
acetyl-CoA + phosphate
propionyl-CoA + phosphate
CoA + propionyl phosphate
additional information
?
-
3'-dephospho-CoA + acetyl phosphate
acetyl-3'-dephospho-CoA + phosphate
-
Substrates: rate is about one tenth of the activity with CoA
Products: -
?
3'-dephospho-CoA + acetyl phosphate
acetyl-3'-dephospho-CoA + phosphate
-
Substrates: rate is about one tenth of the activity with CoA
Products: -
?
acetyl phosphate + CoA
acetyl-CoA + phosphate
Substrates: -
Products: -
?
acetyl phosphate + CoA
acetyl-CoA + phosphate
Substrates: -
Products: -
?
acetyl phosphate + CoA
acetyl-CoA + phosphate
Substrates: with isoform Pta-2, reaction is irreversible, no acetyl phosphate forming reaction can be detected
Products: -
r
acetyl phosphate + CoA
acetyl-CoA + phosphate
-
Substrates: -
Products: -
r
acetyl phosphate + CoA
acetyl-CoA + phosphate
Substrates: -
Products: -
r
acetyl-CoA + arsenate
CoA + acetyl arsenate
-
Substrates: -
Products: -
?
acetyl-CoA + arsenate
CoA + acetyl arsenate
-
Substrates: -
Products: -
?
acetyl-CoA + carnitine
CoA + O-acetylcarnitine
Substrates: -
Products: -
?
acetyl-CoA + carnitine
CoA + O-acetylcarnitine
Substrates: -
Products: -
?
acetyl-CoA + phosphate
acetyl Phosphate + CoA
Substrates: -
Products: -
?
acetyl-CoA + phosphate
acetyl Phosphate + CoA
Substrates: -
Products: -
?
acetyl-CoA + phosphate
acetyl Phosphate + CoA
-
Substrates: -
Products: -
r
acetyl-CoA + phosphate
acetyl Phosphate + CoA
Substrates: -
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: formation of acetyl-CoA is favored
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: in reverse reaction specific for CoA
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: in reverse reaction specific for CoA
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
ir
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
ir
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
ir
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
ir
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: rate of acetyl-CoA synthesis is 10times greater than rate of acetyl phosphate synthesis
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: integral role in acetate metabolism
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
Substrates: -
Products: -
ir
acetyl-CoA + phosphate
CoA + acetyl phosphate
Substrates: -
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: enables growth on acetate as carbon and energy source, required for ethanolamine catabolism
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
Substrates: acetate excretion during growth of Salmonella enterica on ethanolamine requires phosphotransacetylase (EutD) activity, and acetate recapture requires acetyl-CoA synthetase (Acs) and phosphotransacetylase (Pta) activities
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: rate of acetyl-CoA synthesis is 6.5times greater than rate of acetyl phosphate synthesis
Products: -
r
acetyl-phosphate + CoA
acetyl-CoA + phosphate
Substrates: -
Products: -
?
acetyl-phosphate + CoA
acetyl-CoA + phosphate
-
Substrates: ternary complex kinetic echanism rather than a ping-pong kinetic mechanism. Sustrates bind to the enzyme in a random order
Products: -
r
butyryl-CoA + phosphate
CoA + butyryl phosphate
-
Substrates: -
Products: -
?
butyryl-CoA + phosphate
CoA + butyryl phosphate
-
Substrates: at a rate 0.01 as rapid as acetyl-CoA
Products: -
?
butyryl-CoA + phosphate
CoA + butyryl phosphate
-
Substrates: -
Products: -
?
CoA + acetyl phosphate
acetyl-CoA + phosphate
Substrates: -
Products: -
r
CoA + acetyl phosphate
acetyl-CoA + phosphate
Substrates: involved in taurine catabolism
Products: -
?
CoA + acetyl phosphate
acetyl-CoA + phosphate
-
Substrates: -
Products: -
r
CoA + acetyl phosphate
acetyl-CoA + phosphate
Substrates: acetate excretion during growth of Salmonella enterica on ethanolamine requires phosphotransacetylase (EutD) activity, and acetate recapture requires acetyl-CoA synthetase (Acs) and phosphotransacetylase (Pta) activities
Products: -
?
propionyl-CoA + phosphate
CoA + propionyl phosphate
-
Substrates: -
Products: -
?
propionyl-CoA + phosphate
CoA + propionyl phosphate
-
Substrates: at a rate 0.1 to 0.5 as rapid as acetyl-CoA
Products: -
?
propionyl-CoA + phosphate
CoA + propionyl phosphate
-
Substrates: -
Products: -
?
propionyl-CoA + phosphate
CoA + propionyl phosphate
Substrates: reaction of EC 2.3.1.222
Products: -
?
propionyl-CoA + phosphate
CoA + propionyl phosphate
-
Substrates: -
Products: -
?
additional information
?
-
-
Substrates: enzymes is confirmed by total proteome analysis of glycerol-grown cells
Products: -
?
additional information
?
-
-
Substrates: physiological function in anaerobic metabolism of eukaryotic green algae rather than in aerobic acetate activation
Products: -
?
additional information
?
-
-
Substrates: arsenolysis
Products: -
?
additional information
?
-
-
Substrates: arsenolysis
Products: -
?
additional information
?
-
Substrates: enzyme additionally catalyzes reaction with propionyl-CoA, reaction of EC 2.3.1.222, and with butanoyl-CoA, reaction of EC 2.3.1.19
Products: -
-
additional information
?
-
Substrates: enzyme additionally catalyzes reaction with propionyl-CoA, reaction of EC 2.3.1.222, and with butanoyl-CoA, reaction of EC 2.3.1.19
Products: -
-
additional information
?
-
-
Substrates: enzyme additionally catalyzes reaction with propionyl-CoA, reaction of EC 2.3.1.222, and with butanoyl-CoA, reaction of EC 2.3.1.19
Products: -
-
additional information
?
-
Substrates: no substrates: butanoyl-CoA, acetyl phosphate
Products: -
-
additional information
?
-
Substrates: no substrates: butanoyl-CoA, acetyl phosphate
Products: -
-
additional information
?
-
-
Substrates: no substrates: butanoyl-CoA, acetyl phosphate
Products: -
-
additional information
?
-
-
Substrates: mutation of phosphotransacetylase reduces the virulence of Salmonella enterica serovar typhimurium in mice
Products: -
?
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acetyl-CoA + phosphate
CoA + acetyl phosphate
CoA + acetyl phosphate
acetyl-CoA + phosphate
additional information
?
-
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
ir
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
ir
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
ir
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
ir
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: integral role in acetate metabolism
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: enables growth on acetate as carbon and energy source, required for ethanolamine catabolism
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
Substrates: acetate excretion during growth of Salmonella enterica on ethanolamine requires phosphotransacetylase (EutD) activity, and acetate recapture requires acetyl-CoA synthetase (Acs) and phosphotransacetylase (Pta) activities
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
r
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
?
acetyl-CoA + phosphate
CoA + acetyl phosphate
-
Substrates: -
Products: -
r
CoA + acetyl phosphate
acetyl-CoA + phosphate
Substrates: involved in taurine catabolism
Products: -
?
CoA + acetyl phosphate
acetyl-CoA + phosphate
Substrates: acetate excretion during growth of Salmonella enterica on ethanolamine requires phosphotransacetylase (EutD) activity, and acetate recapture requires acetyl-CoA synthetase (Acs) and phosphotransacetylase (Pta) activities
Products: -
?
additional information
?
-
-
Substrates: physiological function in anaerobic metabolism of eukaryotic green algae rather than in aerobic acetate activation
Products: -
?
additional information
?
-
-
Substrates: mutation of phosphotransacetylase reduces the virulence of Salmonella enterica serovar typhimurium in mice
Products: -
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Fe2+
-
required, Fe2+ or Mn2+, Mn2+ is 50-75% as effective as Fe2+
Mn2+
-
required, Fe2+ or Mn2+, Mn2+ is 50-75% as effective as Fe2+
Na+
-
less effective than NH4+ and K+
phosphate
-
1 mM, weak activation
Tris
-
maximum activity with Tris buffer, with HEPES and MES catalysis is lowered by ca. 15%
K+
-
3.4fold stimulation at 10 mM
K+
-
enzyme is activated by low concentrations of NH4+, K+ and Na+, sequence of effectiveness: NH4+, K+, Na+
K+
-
rate of arsenolysis increases with increasing potassium or ammonium salt concentration and reaches a maximum rate at 0.02 to 0.03 M salt concentration
K+
-
enzyme is inactive in absence of K+ or NH4+, maximal activation at about 0.02 M
K+
-
K+ or NH4+ at concentration above 10 mM required for maximum activity
K+
-
maximum activity in the presence of 20 mM KCl
KCl
-
stimulates
KCl
-
stimulates enzyme activity 2.5-fold
NH4+
-
5.2fold stimulation at 10 mM
NH4+
-
enzyme is activated by low concentrations of NH4+, K+ and Na+, sequence of effectiveness: NH4+, K+, Na+
NH4+
-
rate of arsenolysis increases with increasing potassium or ammonium salt concentration and reaches a maximum rate at 0.02 to 0.03 M salt concentration
NH4+
-
required for maximum activity, optimum at 7 mM (NH4)2SO4
NH4+
-
K+ or NH4+ at concentration above 10 mM required for maximum activity, enzyme is inactive in absence of K+ or NH4+, maximal activation at about 0.02 M
NH4+
-
maximum activity in the presence of 20 mM NH4Cl
additional information
-
mechanism of activation by univalent cations
additional information
-
no activity with: Fe3+, Zn2+, Mg2+, Co2+, Ni2+, Sn2+, Cu2+, Mo6+, K+, NH4+
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