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Literature summary for 2.3.1.8 extracted from

  • Yang, X.; Sun, W.; Shen, H.; Zhang, S.; Jiao, X.; Zhao, Z.
    Expression of phosphotransacetylase in Rhodosporidium toruloides leading to improved cell growth and lipid production (2018), RSC Adv., 8, 24673-24678 .
No PubMed abstract available

Application

Application Comment Organism
synthesis overexpression of phosphotransacetylase in the yeast Rhodosporidium toruloides for enhanced cell growth and lipid production. Compared with the parental strain, the engineered strain shows significant improvement in glucose consumption, cell growth and lipid accumulation when cultivated under nitrogen limited conditions in an Erlenmeyer flask as well as a stirred tank bioreactor. The phosphotransacetylase enzyme has little direct effects on the enzymes of fatty acid biosynthetic pathway, but might facilitate the fatty acid precursor acetyl-CoA supply Bacillus subtilis

Organism

Organism UniProt Comment Textmining
Bacillus subtilis
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