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Synonyms
oxygenase, catechol 2,3-dioxygenase, catechol-2,3-dioxygenase, metapyrocatechase, catechol 2,3-oxygenase, meta-cleavage dioxygenase, catechol 2,3 dioxygenase, c23os, c2,3o, 3sc23o,
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2,2',3-trihydroxybiphenylether + O2
?
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?
2,3-dihydroxybiphenyl + O2
?
2,3-dihydroxybiphenylcatechol + O2
?
Halalkalibacterium ligniniphilum
WP_017726464.1
% of the activity as compared to 3-ethylcatechol
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?
2,4-dichlorophenol + O2
?
2,6-dichlorophenol + O2
?
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?
3,4-dihydroxybenzoate + O2
?
3,4-dimethylcatechol + O2
2-hydroxy-5-methyl-6-oxo-hepta-2,4-dienoate
3,5-dichlorocatechol + O2
2-hydroxy-3,5-dimethyl-6-oxohexa-2,4-dienoic acid
30.8% of the activity as compared to catechol
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-
?
3,5-dichlorocatechol + O2
?
3,5-dimethylcatechol + O2
2-hydroxy-3,5-dimethyl-6-oxohexa-2,4-dienoic acid
3-chlorocatechol + O2
2-chloro-2-hydroxy-6-oxohexa-2,4-dienoate
3-chlorocatechol + O2
2-hydroxy-6-oxohepta-2,4-dienoate
3-chlorocatechol + O2
3-chloro-2-hydroxymuconate semialdehyde
3-ethylcatechol + O2
?
Halalkalibacterium ligniniphilum
WP_017726464.1
best substrate. The enzyme can cleave the catechol ring when substitutions occur at C3 more efficiently than C4 substitutes. The enzyme can cleave aromatic compounds with two 6-carbon ring structures
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?
3-formylcatechol + O2
3-formyl-2-hydroxymuconate semialdehyde
3-hydroxycatechol + O2
3-hydroxymuconic acid
3-isopropylcatechol + O2
?
3-methoxycatechol + O2
2-hydroxy-3-methoxy-6-oxohexa-2,4-dienoate
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-
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?
3-methoxycatechol + O2
2-hydroxy-3-methoxymuconate semialdehyde
3-methylcatechol + O2
2-hydroxy-3-methoxymuconate semialdehyde
211.7% compared to the activity with catechol
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?
3-methylcatechol + O2
2-hydroxy-3-methylmuconate semialdehyde
3-methylcatechol + O2
2-hydroxy-3-methylmuconate-6-semialdehyde
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?
3-methylcatechol + O2
2-hydroxy-6-oxohepta-2,4-dienoate
3-methylcatechol + O2
2-hydroxy-6-oxohepta-2,4-dienoic acid
3-methylcatechol + O2
cis,cis-2-hydroxy-6-oxohepta-2,4-dienoate
3-phenylcatechol + O2
2-hydroxy-3-phenylmuconate semialdehyde
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?
3-sulfocatechol + O2 + H2O
(2E,4Z)-2-hydroxymuconate + bisulfite + H+
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?
3-vinylcatechol + O2
?
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?
4,5-dichlorocatechol + O2
?
4-bromocatechol + O2
4-bromo-2-hydroxymuconate semialdehyde
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?
4-chlorocatechol + O2
4-chloro-2-hydroxymuconate semialdehyde
4-chlorocatechol + O2
5-chloro-2-hydroxy-6-oxohexa-2,4-dienoate
4-chlorocatechol + O2
5-chloro-2-hydroxymuconic semialdehyde
4-chlorophenol + O2
?
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?
4-ethylcatechol + O2
4-ethyl-2-hydroxymuconate semialdehyde
4-fluorocatechol + O2
3-fluoro-2-hydroxy-6-oxohexa-2,4-dienoate
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?
4-formylcatechol + O2
4-formyl-2-hydroxymuconate semialdehyde
4-hydroxymethylcatechol + O2
2-hydroxy-4-hydroxymethylmuconate semialdehyde
rapid inactivation of enzyme during turnover
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?
4-methylcatechol + O2
2-hydroxy-3-methyl-6-oxohexa-2,4-dienoate
4-methylcatechol + O2
2-hydroxy-4-methyl-6-oxohexa-2,4-dienoate
4-methylcatechol + O2
2-hydroxy-4-methylmuconate semialdehyde
4-methylcatechol + O2
2-hydroxy-5-methyl-6-oxohexa-2,4-dienoate
4-n-butylcatechol + O2
?
activity is 1.85fold higher than with catechol
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?
4-n-heptylcatechol + O2
?
45% of the activity with catechol
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?
4-n-hexylcatechol + O2
?
53% of the activity with catechol
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?
4-n-nonylcatechol + O2
?
10% of the activity with catechol
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?
4-nitrocatechol + O2
2-hydroxy-4-nitromuconate semialdehyde
4-nitrophenol + O2
?
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best substrate
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?
alkylcatechol + O2
?
degradation of aromatic compounds
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?
catechol + O2
2-hydroxymuconate semialdehyde
catechol + O2
2-hydroxymuconate-6-semialdehyde
catechol + O2
cis,cis-muconate
methanol + O2
?
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?
methylbenzene + O2
?
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phenol + O2
2-hydroxymuconic semialdehyde
propanol + O2
?
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?
protocatechualdehyde + O2
?
protocatechuate + O2
?
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?
tetrachlorohydroquinone + O2
?
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immobilized enzyme, no activity with the free enzyme
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?
additional information
?
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2,3-dihydroxybiphenyl + O2
?
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5% of the activity with catechol
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?
2,3-dihydroxybiphenyl + O2
?
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5% of the activity with catechol
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?
2,3-dihydroxybiphenyl + O2
?
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?
2,3-dihydroxybiphenyl + O2
?
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?
2,3-dihydroxybiphenyl + O2
?
1.3% of the activity with 2,3-dihydroxybiphenyl
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?
2,3-dihydroxybiphenyl + O2
?
1.3% of the activity with 2,3-dihydroxybiphenyl
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?
2,3-dihydroxybiphenyl + O2
?
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?
2,3-dihydroxybiphenyl + O2
?
poor substrate
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?
2,3-dihydroxybiphenyl + O2
?
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?
2,3-dihydroxybiphenyl + O2
?
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?
2,3-dihydroxybiphenyl + O2
?
poor substrate
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?
2,3-dihydroxybiphenyl + O2
?
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?
2,3-dihydroxybiphenyl + O2
?
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?
2,3-dihydroxybiphenyl + O2
?
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?
2,3-dihydroxybiphenyl + O2
?
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?
2,3-dihydroxybiphenyl + O2
?
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?
2,3-dihydroxybiphenyl + O2
?
9.47% compared to the activity with catechol
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?
2,3-dihydroxybiphenyl + O2
?
9.47% compared to the activity with catechol
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?
2,4-dichlorophenol + O2
?
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?
2,4-dichlorophenol + O2
?
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?
2,4-dichlorophenol + O2
?
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?
2,4-dichlorophenol + O2
?
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?
2,4-dichlorophenol + O2
?
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?
2-chlorophenol + O2
?
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?
2-chlorophenol + O2
?
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?
2-methylphenol + O2
?
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?
2-methylphenol + O2
?
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?
2-methylphenol + O2
?
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?
3,4-dihydroxybenzoate + O2
?
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?
3,4-dihydroxybenzoate + O2
?
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?
3,4-dihydroxybenzoate + O2
?
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weak
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?
3,4-dimethylcatechol + O2
2-hydroxy-5-methyl-6-oxo-hepta-2,4-dienoate
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?
3,4-dimethylcatechol + O2
2-hydroxy-5-methyl-6-oxo-hepta-2,4-dienoate
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?
3,5-dichlorocatechol + O2
?
-
-
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?
3,5-dichlorocatechol + O2
?
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immobilized enzyme, no activity with the free enzyme
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?
3,5-dichlorocatechol + O2
?
-
immobilized enzyme, no activity with the free enzyme
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?
3,5-dimethylcatechol + O2
2-hydroxy-3,5-dimethyl-6-oxohexa-2,4-dienoic acid
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?
3,5-dimethylcatechol + O2
2-hydroxy-3,5-dimethyl-6-oxohexa-2,4-dienoic acid
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?
1.13.11.2 catechol 2,3-dioxygenase
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