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BRENDA support

Ligand 2-hydroxymuconate-6-semialdehyde

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Basic Ligand Information

Molecular Structure
Picture of 2-hydroxymuconate-6-semialdehyde (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H6O4
2-hydroxymuconate-6-semialdehyde
KGLCZTRXNNGESL-REDYYMJGSA-N
Synonyms:
2-hydroxy-6-oxohexa-2,4-dienoate, 2-hydroxymuconate 6-semialdehyde, 2-hydroxymuconate semialdehyde, 2-hydroxymuconic 6-semialdehyde, 2-hydroxymuconic acid semialdehyde, 2-hydroxymuconic semialdehyde, alpha-hydroxy-muconic semialdehyde, alpha-hydroxymuconic semialdehyde


Show all pahtways known for Show all BRENDA pathways known for 2-hydroxymuconate-6-semialdehyde

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-hydroxymuconate-6-semialdehyde + NAD+ + H2O = (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + NADH + 2 H+
show the reaction diagram
-
2-hydroxymuconic semialdehyde + H2O = ?
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2,3-dihydroxybenzoate + O2 = CO2 + alpha-hydroxymuconic semialdehyde
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (13 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-hydroxymuconic semialdehyde + H2O = ?
show the reaction diagram
-
2-hydroxymuconic semialdehyde + H2O = ?
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2,3-dihydroxybenzoate + O2 = CO2 + alpha-hydroxymuconic semialdehyde
show the reaction diagram
-
2,3-dihydroxybenzoate + O2 = CO2 + alpha-hydroxymuconic semialdehyde
show the reaction diagram
-
catechol + O2 = 2-hydroxy-6-oxohexa-2,4-dienoate
show the reaction diagram
-
catechol + O2 = 2-hydroxymuconic acid semialdehyde
show the reaction diagram
-
catechol + O2 = 2-hydroxymuconic 6-semialdehyde
show the reaction diagram
-
catechol + O2 = 2-hydroxymuconate semialdehyde
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (4 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
21900
-
pH 8.5, 25°C
0.9
-
pH 8.5, 25°C, recombinant enzyme

KM Value (12 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for 2-hydroxymuconate-6-semialdehyde

ChEBI
PubChem
ChEBI
PubChem