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Literature summary for 1.13.11.2 extracted from

  • Comte, A.; Christen, P.; Davidson, S.; Pophillat, M.; Lorquin, J.; Auria, R.; Simon, G.; Casalot, L.
    Biochemical, transcriptional and translational evidences of the phenol-meta-degradation pathway by the hyperthermophilic (2013), PLoS One, 8, e82397.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Saccharolobus solfataricus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
catechol + O2 Saccharolobus solfataricus both the ortho- and the meta-degradation pathways are functional in presence of phenol. However, the activation of the catechol 2,3-dioxygenase, only when phenol is present, and the accumulation of only intermediary compounds related to this pathway lead us to the conclusion that the aromatic ring is preferentially opened through the meta-pathway 2-hydroxymuconate semialdehyde
-
?
catechol + O2 Saccharolobus solfataricus 98/2 both the ortho- and the meta-degradation pathways are functional in presence of phenol. However, the activation of the catechol 2,3-dioxygenase, only when phenol is present, and the accumulation of only intermediary compounds related to this pathway lead us to the conclusion that the aromatic ring is preferentially opened through the meta-pathway 2-hydroxymuconate semialdehyde
-
?

Organism

Organism UniProt Comment Textmining
Saccharolobus solfataricus V5W6K5
-
-
Saccharolobus solfataricus 98/2 V5W6K5
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-chlorocatechol + O2 the enzyme shows the highest activity against catechol and 4-chlorocatechol Saccharolobus solfataricus ?
-
?
4-chlorocatechol + O2 the enzyme shows the highest activity against catechol and 4-chlorocatechol Saccharolobus solfataricus 98/2 ?
-
?
catechol + O2 both the ortho- and the meta-degradation pathways are functional in presence of phenol. However, the activation of the catechol 2,3-dioxygenase, only when phenol is present, and the accumulation of only intermediary compounds related to this pathway lead us to the conclusion that the aromatic ring is preferentially opened through the meta-pathway Saccharolobus solfataricus 2-hydroxymuconate semialdehyde
-
?
catechol + O2 the enzyme shows the highest activity against catechol and 4-chlorocatechol Saccharolobus solfataricus 2-hydroxymuconate semialdehyde
-
?
catechol + O2 both the ortho- and the meta-degradation pathways are functional in presence of phenol. However, the activation of the catechol 2,3-dioxygenase, only when phenol is present, and the accumulation of only intermediary compounds related to this pathway lead us to the conclusion that the aromatic ring is preferentially opened through the meta-pathway Saccharolobus solfataricus 98/2 2-hydroxymuconate semialdehyde
-
?
catechol + O2 the enzyme shows the highest activity against catechol and 4-chlorocatechol Saccharolobus solfataricus 98/2 2-hydroxymuconate semialdehyde
-
?

Synonyms

Synonyms Comment Organism
C23D
-
Saccharolobus solfataricus
ssol_2912
-
Saccharolobus solfataricus

Expression

Organism Comment Expression
Saccharolobus solfataricus ssol_2912 is undetectable when the strain is harvested from the medium with glucose as the sole carbon source, it greatly increased when the strain is harvested from the media with phenol up

General Information

General Information Comment Organism
physiological function both the ortho- and the meta-degradation pathways are functional in presence of phenol. However, the activation of the catechol 2,3-dioxygenase, only when phenol is present, and the accumulation of only intermediary compounds related to this pathway lead us to the conclusion that the aromatic ring is preferentially opened through the meta-pathway Saccharolobus solfataricus