Information on EC 3.4.24.3 - microbial collagenase

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The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
3.4.24.3
-
RECOMMENDED NAME
GeneOntology No.
microbial collagenase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
Digestion of native collagen in the triple helical region at -/-Gly bonds. With synthetic peptides, a preference is shown for Gly at P3 and P1', Pro and Ala at P2 and P2', and hydroxyproline, Ala or Arg at P3'
show the reaction diagram
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis of peptide bond
-
-
endopeptidase
-
CAS REGISTRY NUMBER
COMMENTARY hide
9001-12-1
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
-
-
Manually annotated by BRENDA team
Clostridium capitorale
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
isoform ColT
UniProt
Manually annotated by BRENDA team
Clostridium welchii
-
-
-
Manually annotated by BRENDA team
L43-1 strain
-
-
Manually annotated by BRENDA team
L43-1 strain
-
-
Manually annotated by BRENDA team
Empedobacter collagenolyticum
-
-
-
Manually annotated by BRENDA team
strain MO-1
UniProt
Manually annotated by BRENDA team
Bacteroides gingivalis
-
-
Manually annotated by BRENDA team
B-30
-
-
Manually annotated by BRENDA team
B-30
-
-
Manually annotated by BRENDA team
CYK279H
-
-
Manually annotated by BRENDA team
CYK279H
-
-
Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-(S-methylcysteine)-Pro-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala + Ala-(S-methylcysteine)-Pro-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00018
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Ala-Gly-Pro-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala + Ala-Ala-Gly-Pro-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00204
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Ala-Pro-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Ala-Pro-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00095
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Ala-Tyr-Lys-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala + Ala-Ala-Tyr-Lys-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00309
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Arg-Pro-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala + Ala-Arg-Pro-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00026
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Asn-Pro-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala + Ala-Asn-Pro-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00022
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Asp-Pro-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala + Ala-Asp-Pro-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00022
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gln-Pro-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala + Ala-Gln-Pro-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.0003
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Glu-Pro-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala + Ala-Glu-Pro-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00022
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-(S-methylcysteine)-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-(S-methylcysteine)-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00072
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Ala-Ala-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Ala-Ala-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00082
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Ala-Ala-Arg-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Ala-Ala-Arg-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00595
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Ala-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Ala-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00037
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Ala-Ala-Gly-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Ala-Ala-Gly-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00124
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Ala-Ala-Ile-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Ala-Ala-Ile-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00086
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Ala-Ala-Leu-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Ala-Ala-Leu-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00134
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Ala-Ala-Lys-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Ala-Ala-Lys-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.006
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Ala-Ala-Met-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Ala-Ala-Met-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00131
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Ala-Ala-Phe-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Ala-Ala-Phe-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00051
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Ala-Ala-Pro-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Ala-Ala-Pro-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00565
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Ala-Ala-Trp-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Ala-Ala-Trp-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00073
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Ala-Ala-Tyr-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Ala-Ala-Tyr-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00113
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Ala-Ala-Val-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Ala-Ala-Val-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00056
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Ala-Asn-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala + Ala-Gly-Ala-Asn-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00376
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Ala-Asp-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala + Ala-Gly-Ala-Asp-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00043
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Ala-Gln-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala + Ala-Gly-Ala-Gln-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00435
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Ala-Glu-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala + Ala-Gly-Ala-Glu-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00042
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Ala-Ser-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Ala-Ser-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00405
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Ala-Thr-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Ala-Thr-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00466
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Arg-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Arg-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00011
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Asn-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Asn-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00096
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Asp-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Asp-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.0004
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Gln-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Gln-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00049
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Glu-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Glu-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00035
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Gly-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Gly-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00042
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-His-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-His-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00084
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Ile-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Ile-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00065
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Leu-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Leu-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00029
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Lys-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Lys-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00017
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Met-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Met-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00027
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Phe-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Phe-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00056
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Pro-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Pro-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.008
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Ser-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Ser-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00098
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Thr-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Thr-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00082
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Trp-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Trp-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00037
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Tyr-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Tyr-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00038
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Gly-Val-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala + Gly-Val-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00039
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-His-Pro-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala + Ala-His-Pro-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00029
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Ile-Pro-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala + Ala-Ile-Pro-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00017
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Leu-Pro-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala + Ala-Leu-Pro-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00021
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Lys-Pro-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala + Ala-Lys-Pro-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00021
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Met-Pro-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala + Ala-Met-Pro-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00028
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Phe-Pro-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala + Ala-Phe-Pro-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00022
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Pro-Lys-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala + Ala-Pro-Lys-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00276
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Pro-Pro-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala + Ala-Pro-Pro-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00088
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Ser-Pro-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala + Ala-Ser-Pro-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.0007
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Thr-Pro-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala + Ala-Thr-Pro-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.0004
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Trp-Pro-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala + Ala-Trp-Pro-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00014
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Tyr-Pro-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala + Ala-Tyr-Pro-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00029
-
-
?
(7-hydroxycoumarin-4-propanoyl)-Ala-Ala-Val-Pro-Ala-beta-Ala + H2O
(7-hydroxycoumarin-4-propanoyl)-Ala + Ala-Val-Pro-Ala-beta-Ala
show the reaction diagram
-
ratio of turnover number to Km-value is 0.00036
-
-
?
2-furanacryloyl-Leu-Gly-Pro-Ala + H2O
2-furanacryloyl-Leu + Gly-Pro-Ala
show the reaction diagram
4-phenylazobenzyloxycarbonyl-Pro-Leu-Gly-Pro-Arg + H2O
4-phenylazobenzyloxycarbonyl-Pro-Leu + Gly-Pro-Arg
show the reaction diagram
Azocoll + H2O
Hydrolyzed azocoll
show the reaction diagram
azokoll + H2O
?
show the reaction diagram
-
-
-
?
Bradykinin + H2O
?
show the reaction diagram
-
-
-
-
?
carbobenzoxy-Gly-Pro-Gly-Gly-Pro-Ala + H2O
carbobenzoxy-Gly-Pro-Gly + Gly-Pro-Ala
show the reaction diagram
carbobenzoxy-Gly-Pro-Leu-Gly-Pro + H2O
carbobenzoxy-Gly-Pro-Leu + Gly-Pro
show the reaction diagram
casein + H2O
?
show the reaction diagram
Collagen + H2O
?
show the reaction diagram
Collagen + H2O
Hydrolyzed collagen
show the reaction diagram
Collagen type I + H2O
?
show the reaction diagram
Collagen type III + H2O
?
show the reaction diagram
-
-
Clostridium collagenase itself and the degradation products of type I and III collagens lead toan increase in keratinocyte and fibroblast migration
-
?
collagen type IV + H2O
?
show the reaction diagram
-
-
degradation products of collagen type IV induce fibroblast migration
-
?
collagen type V + H2O
?
show the reaction diagram
-
-
-
-
?
furanacryloyl-Leu-Gly-Pro-Ala + H2O
furanacryloyl-Leu + Gly-Pro-Ala
show the reaction diagram
-
-
-
-
?
furylacryloyl-L-Phe-Gly-Gly
?
show the reaction diagram
-
-
-
-
?
furylacryloyl-Leu-Gly-Pro-Ala + H2O
furylacryloyl-Leu + Gly-Pro-Ala
show the reaction diagram
GDPCMPIISN + H2O
?
show the reaction diagram
Gelatin + H2O
Hydrolyzed gelatin
show the reaction diagram
N-[3-(2-furyl) acryloyl]-L-Leu-Gly-L-Pro-L-Ala + H2O
?
show the reaction diagram
-
-
-
-
?
Type I collagen + H2O
?
show the reaction diagram
additional information
?
-
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
Collagen + H2O
?
show the reaction diagram
Type I collagen + H2O
?
show the reaction diagram
additional information
?
-
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Calcium
-
binding of calcium ions triggers the formation of a cis peptide bond in the collagen-binding domain. The calcium ions not only stabilize the cis peptide bond thermodynamically but also catalyze its formation. The free energy barrier to the formation of the cis peptide bond decreases from 21.4 kcal/mol in the absence of calciumions to 10.3 kcal/mol in their presence. The calcium ions electrostatically stabilize the lone pair on the nitrogen atom that forms during the isomerization. Their attraction to acidic amino acid side chains and formation of a hydrogen bond network constrain the peptide backbone in a way that makes it easier for the nitrogen to pyramidalize
Co2+
-
activates at low concentration, inhibits at high concentration
Li+
-
activates
INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1,10-phenanthroline
2-(1-benzyl-3-naphthalen-1-yl-ureido)-3-methyl-butyric acid
-
-
2-(1-benzyl-3-naphthalen-1-yl-ureido)-N-hydroxy-3-methyl-butyramide
-
-
2-(3-benzoyl-1-benzyl-thioureido)-N-hydroxy-3-methyl-butyramide
-
-
2-(benzyl[[(2,4-difluorophenyl)amino]carbonyl]amino)-3-methylbutanoic acid
-
-
2-(benzyl[[(2,4-difluorophenyl)amino]carbonyl]amino)-N-hydroxy-3-methylbutanamide
-
-
2-(benzyl[[(2,4-difluorophenyl)amino]carbonyl]amino)-N-hydroxypropanamide
-
-
2-(benzyl[[(2,4-difluorophenyl)amino]carbonyl]amino)propanoic acid
-
-
2-(benzyl[[(3,4-dichlorophenyl)amino]carbonyl]amino)-3-methylbutanoic acid
-
-
2-(benzyl[[(3,4-dichlorophenyl)amino]carbonyl]amino)-N-hydroxy-3-methylbutanamide
-
-
2-(benzyl[[(3,4-dichlorophenyl)amino]carbonyl]amino)-N-hydroxypropanamide
-
-
2-(benzyl[[(3,4-dichlorophenyl)amino]carbonyl]amino)propanoic acid
-
-
2-(benzyl[[(3-chlorophenyl)amino]carbonyl]amino)-3-methylbutanoic acid
-
-
2-(benzyl[[(3-chlorophenyl)amino]carbonyl]amino)-N-hydroxy-3-methylbutanamide
-
-
2-(benzyl[[(3-chlorophenyl)amino]carbonyl]amino)-N-hydroxypropanamide
-
-
2-(benzyl[[(3-chlorphenyl)amino]carbonyl]amino)propanoic acid
-
-
2-(benzyl[[(4-chlorophenyl)amino]carbonyl]amino)-3-methylbutanoic acid
-
-
2-(benzyl[[(4-chlorophenyl)amino]carbonyl]amino)-N-hydroxy-3-methylbutanamide
-
-
2-(benzyl[[(4-chlorophenyl)amino]carbonyl]amino)-N-hydroxypropanamide
-
-
2-(benzyl[[(4-chlorphenyl)amino]carbonyl]amino)propanoic acid
-
-
2-(benzyl[[(4-fluorophenyl)amino]carbonyl]amino)-3-methylbutanoic acid
-
-
2-(benzyl[[(4-fluorophenyl)amino]carbonyl]amino)-N-hydroxy-3-methylbutanamide
-
-
2-(benzyl[[(4-fluorophenyl)amino]carbonyl]amino)-N-hydroxypropanamide
-
-
2-(benzyl[[(4-fluorophenyl)amino]carbonyl]amino)propanoic acid
-
-
2-(benzyl[[3-(trifluoromethyl)phenyl]sulfonyl]amino)-N-hydroxypropanamide
-
-
2-(benzyl[[3-(trifluoromethyl)phenyl]sulfonyl]amino)propanoic acid
-
-
2-mercaptoethanol
2-[benzyl(1-naphthylsulfonyl)amino]propanoic acid
-
-
2-[benzyl(2-naphthylsulfonyl)amino]propanoic acid
-
-
2-[benzyl(5-methylnaphthalene-1-sulfonyl)amino]-3-methylbutanoic acid
-
-
2-[benzyl(benzylsulfonyl)amino]-3-methylbutanoic acid
-
-
2-[benzyl(benzylsulfonyl)amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl(benzylsulfonyl)amino]-N-hydroxypropanamide
-
-
2-[benzyl(benzylsulfonyl)amino]propanoic acid
-
-
2-[benzyl(methylsulfonyl)amino]-3-methylbutanoic acid
-
-
2-[benzyl(methylsulfonyl)amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl(methylsulfonyl)amino]-N-hydroxypropanamide
-
-
2-[benzyl(methylsulfonyl)amino]propanoic acid
-
-
2-[benzyl(naphthalene-1-sulfonyl)amino]-3-methylbutanoic acid
-
-
2-[benzyl(naphthalene-2-sulfonyl)amino]-3-methylbutanoic acid
-
-
2-[benzyl(phenylcarbonothioyl)amino]-N-hydroxypropanamide
-
-
2-[benzyl(phenylsulfonyl)amino]-3-methylbutanoic acid
-
-
2-[benzyl(phenylsulfonyl)amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl(phenylsulfonyl)amino]-N-hydroxypropanamide
-
-
2-[benzyl(phenylsulfonyl)amino]propanoic acid
-
-
2-[benzyl(thien-2-ylsulfonyl)amino]-3-methylbutanoic acid
-
-
2-[benzyl(thien-2-ylsulfonyl)amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl(thien-2-ylsulfonyl)amino]-N-hydroxypropanamide
-
-
2-[benzyl(thien-2-ylsulfonyl)amino]propanoic acid
-
-
2-[benzyl([[(2-methylphenyl)sulfonyl]amino]carbonyl)amino]-3-methylbutanoic acid
-
-
2-[benzyl([[(2-methylphenyl)sulfonyl]amino]carbonyl)amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl([[(2-methylphenyl)sulfonyl]amino]carbonyl)amino]-N-hydroxyacetamide
-
-
2-[benzyl([[(2-methylphenyl)sulfonyl]amino]carbonyl)amino]-N-hydroxypropanamide
-
-
2-[benzyl([[(2-methylphenyl)sulfonyl]amino]carbonyl)amino]propanoic acid
-
-
2-[benzyl([[(4-chlorophenyl)sulfonyl]amino]carbonyl)amino]-3-methylbutanoic acid
-
-
2-[benzyl([[(4-chlorophenyl)sulfonyl]amino]carbonyl)amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl([[(4-chlorophenyl)sulfonyl]amino]carbonyl)amino]-N-hydroxyacetamide
-
-
2-[benzyl([[(4-chlorophenyl)sulfonyl]amino]carbonyl)amino]-N-hydroxypropanamide
-
-
2-[benzyl([[(4-chlorophenyl)sulfonyl]amino]carbonyl)amino]propanoic acid
-
-
2-[benzyl([[(4-fluorophenyl)sulfonyl]amino]carbonyl)amino]-3-methylbutanoic acid
-
-
2-[benzyl([[(4-fluorophenyl)sulfonyl]amino]carbonyl)amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl([[(4-fluorophenyl)sulfonyl]amino]carbonyl)amino]-N-hydroxyacetamide
-
-
2-[benzyl([[(4-fluorophenyl)sulfonyl]amino]carbonyl)amino]-N-hydroxypropanamide
-
-
2-[benzyl([[(4-fluorophenyl)sulfonyl]amino]carbonyl)amino]propanoic acid
-
-
2-[benzyl([[(4-methylphenyl)sulfonyl]amino]carbonyl)amino]-3-methylbutanoic acid
-
-
2-[benzyl([[(4-methylphenyl)sulfonyl]amino]carbonyl)amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl([[(4-methylphenyl)sulfonyl]amino]carbonyl)amino]-N-hydroxyacetamide
-
-
2-[benzyl([[(4-methylphenyl)sulfonyl]amino]carbonyl)amino]-N-hydroxypropanamide
-
-
2-[benzyl([[(4-methylphenyl)sulfonyl]amino]carbonyl)amino]propanoic acid
-
-
2-[benzyl-(2,4,6-tripropyl-benzenesulfonyl)-amino]-N-hydroxy-propionamide
-
-
2-[benzyl-(3,5-dichloro-2-hydroxy-benzenesulfonyl)-amino]-N-hydroxy-propionamide
-
-
2-[benzyl-(3,5-dichloro-2-hydroxy-benzenesulfonyl)-amino]-propionic acid
-
-
2-[benzyl-(3-tert-butoxycarbonylamino-4-methoxy-benzenesulfonyl)-amino]-propionic acid
-
-
2-[benzyl-(5-dimethylamino-naphthalene-1-sulfonyl)-amino]-N-hydroxy-propionamide
-
-
2-[benzyl-(5-dimethylamino-naphthalene-1-sulfonyl)-amino]-propionic acid
-
-
2-[Benzyl-(5-methylnaphthalene-1-sulfonyl)-amino]-N-hydroxy-3-methyl-butyramide
-
-
2-[benzyl-(heptadecafluorooctane-1-sulfonyl)-amino]-3-methyl-butyric acid
-
-
2-[Benzyl-(heptadecafluorooctane-1-sulfonyl)-amino]-N-hydroxy-3-methyl-butyramide
-
-
2-[Benzyl-(naphthalene-1-sulfonyl)-amino]-N-hydroxy-3-methyl-butyramide
-
-
2-[benzyl-(naphthalene-1-sulfonyl)-amino]-N-hydroxy-propionamide
-
-
2-[Benzyl-(naphthalene-2-sulfonyl)-amino]-N-hydroxy-3-methyl-butyramide
-
-
2-[benzyl-(naphthalene-2-sulfonyl)-amino]-N-hydroxy-propionamide
-
-
2-[benzyl-(toluene-4-sulfonyl)-amino]-N-hydroxy-propionamide
-
-
2-[benzyl[(1-naphthylamino)carbonyl]amino]-N-hydroxypropanamide
-
-
2-[benzyl[(1-naphthylamino)carbonyl]amino]propanoic acid
-
-
2-[benzyl[(2,4,6-trimethylphenyl)sulfonyl]amino]-3-methylbutanoic acid
-
-
2-[benzyl[(2,4,6-trimethylphenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl[(2,4-dinitrophenyl)thio]amino]-3-methylbutanoic acid
-
-
2-[benzyl[(2,4-dinitrophenyl)thio]amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl[(2,4-dinitrophenyl)thio]amino]-N-hydroxypropanamide
-
-
2-[benzyl[(2,4-dinitrophenyl)thio]amino]propanoic acid
-
-
2-[benzyl[(2,5-dichlorophenyl)sulfonyl]amino]-3-methylbutanoic acid
-
-
2-[benzyl[(2,5-dichlorophenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl[(2,5-dichlorophenyl)sulfonyl]amino]-N-hydroxypropanamide
-
-
2-[benzyl[(2,5-dichlorophenyl)sulfonyl]amino]propanoic acid
-
-
2-[benzyl[(2-nitrophenyl)sulfonyl]amino]-3-methylbutanoic acid
-
-
2-[benzyl[(2-nitrophenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl[(2-nitrophenyl)sulfonyl]amino]-N-hydroxypropanamide
-
-
2-[benzyl[(2-nitrophenyl)sulfonyl]amino]propanoic acid
-
-
2-[benzyl[(2-nitrophenyl)thio]amino]-3-methylbutanoic acid
-
-
2-[benzyl[(2-nitrophenyl)thio]amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl[(3,5-dichloro-2-hydroxyphenyl)sulfonyl]amino]-3-methylbutanoic acid
-
-
2-[benzyl[(3,5-dichloro-2-hydroxyphenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl[(3-butyloxycarbonylamino-4-methoxyphenyl)sulfonyl]amino]-3-methylbutanoic acid
-
-
2-[benzyl[(3-butyloxycarbonylamino-4-methoxyphenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl[(3-butyloxycarbonylaminophenyl)sulfonyl]amino]-3-methylbutanoic acid
-
-
2-[benzyl[(3-butyloxycarbonylaminophenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl[(3-carboxyphenyl)sulfonyl]amino]-3-methylbutanoic acid
-
-
2-[benzyl[(3-chloro-4-nitrophenyl)sulfonyl]amino]-3-methylbutanoic acid
-
-
2-[benzyl[(3-chloro-4-nitrophenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl[(3-chloro-4-nitrophenyl)sulfonyl]amino]-N-hydroxypropanamide
-
-
2-[benzyl[(3-chloro-4-nitrophenyl)sulfonyl]amino]propanoic acid
-
-
2-[benzyl[(3-nitrophenyl)sulfonyl]amino]-3-methylbutanoic acid
-
-
2-[benzyl[(3-nitrophenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl[(3-nitrophenyl)sulfonyl]amino]-N-hydroxypropanamide
-
-
2-[benzyl[(3-nitrophenyl)sulfonyl]amino]propanoic acid
-
-
2-[benzyl[(3-nitrophenyl)thio]amino]-N-hydroxypropanamide
-
-
2-[benzyl[(3-nitrophenyl)thio]amino]propanoic acid
-
-
2-[benzyl[(3-trifluoromethylphenyl)sulfonyl]amino]-3-methylbutanoic acid
-
-
2-[benzyl[(3-trifluoromethylphenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl[(4-acetamidophenyl)sulfonyl]amino]-3-methylbutanoic acid
-
-
2-[benzyl[(4-acetamidophenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl[(4-bromophenyl)sulfonyl]amino]-3-methylbutanoic acid
-
-
2-[benzyl[(4-bromophenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl[(4-bromophenyl)sulfonyl]amino]-N-hydroxypropanamide
-
-
2-[benzyl[(4-bromophenyl)sulfonyl]amino]propanoic acid
-
-
2-[benzyl[(4-butyloxycarbonylaminophenyl)sulfonyl]amino]-3-methylbutanoic acid
-
-
2-[benzyl[(4-butyloxycarbonylaminophenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl[(4-carboxyphenyl)sulfonyl]amino]-3-methylbutanoic acid
-
-
2-[benzyl[(4-chlorophenyl)sulfonyl]amino]-3-methylbutanoic acid
-
-
2-[benzyl[(4-chlorophenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl[(4-chlorophenyl)sulfonyl]amino]-N-hydroxypropanamide
-
-
2-[benzyl[(4-chlorophenyl)sulfonyl]amino]propanoic acid
-
-
2-[benzyl[(4-fluorophenyl)sulfonyl]amino]-3-methylbutanoic acid
-
-
2-[benzyl[(4-fluorophenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl[(4-fluorophenyl)sulfonyl]amino]-N-hydroxypropanamide
-
-
2-[benzyl[(4-fluorophenyl)sulfonyl]amino]propanoic acid
-
-
2-[benzyl[(4-iodophenyl)sulfonyl]amino]-3-methylbutanoic acid
-
-
2-[benzyl[(4-iodophenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl[(4-iodophenyl)sulfonyl]amino]-N-hydroxypropanamide
-
-
2-[benzyl[(4-iodophenyl)sulfonyl]amino]propanoic acid
-
-
2-[benzyl[(4-methoxyphenyl)sulfonyl]amino]-3-methylbutanoic acid
-
-
2-[benzyl[(4-methoxyphenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl[(4-methoxyphenyl)sulfonyl]amino]-N-hydroxypropanamide
-
-
2-[benzyl[(4-methylphenyl)sulfonyl]amino]-3-methylbutanoic acid
-
-
2-[benzyl[(4-methylphenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl[(4-methylphenyl)sulfonyl]amino]propanoic acid
-
-
2-[benzyl[(4-nitrophenyl)sulfonyl]amino]-3-methylbutanoic acid
-
-
2-[benzyl[(4-nitrophenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl[(4-nitrophenyl)sulfonyl]amino]-N-hydroxypropanamide
-
-
2-[benzyl[(4-nitrophenyl)sulfonyl]amino]propanoic acid
-
-
2-[benzyl[(4-nitrophenyl)thio]amino]-3-methylbutanoic acid
-
-
2-[benzyl[(4-nitrophenyl)thio]amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl[(4-nitrophenyl)thio]amino]-N-hydroxypropanamide
-
-
2-[benzyl[(4-nitrophenyl)thio]amino]propanoic acid
-
-
2-[benzyl[(dimethylamino)sulfonyl]amino]-3-methylbutanoic acid
-
-
2-[benzyl[(dimethylamino)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl[(dimethylamino)sulfonyl]amino]-N-hydroxypropanamide
-
-
2-[benzyl[(dimethylamino)sulfonyl]amino]propanoic acid
-
-
2-[benzyl[(heptadecafluorooctyl)sulfonyl]amino]propanoic acid
-
-
2-[benzyl[(heptadecfluorooctyl)sulfonyl]amino]-N-hydroxypropanamide
-
-
2-[benzyl[(nonafluorobutyl)sulfonyl]amino]-3-methylbutanoic acid
-
-
2-[benzyl[(nonafluorobutyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl[(nonafluorobutyl)sulfonyl]amino]-N-hydroxypropanamide
-
-
2-[benzyl[(nonafluorobutyl)sulfonyl]amino]propanoic acid
-
-
2-[benzyl[(pentafluorophenyl)sulfonyl]amino]-3-methylbutanoic acid
-
-
2-[benzyl[(pentafluorophenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl[(pentafluorophenyl)sulfonyl]amino]-N-hydroxypropanamide
-
-
2-[benzyl[(pentafluorophenyl)sulfonyl]amino]propanoic acid
-
-
2-[benzyl[(trichloromethyl)sulfonyl]amino]-3-methylbutanoic acid
-
-
2-[benzyl[(trichloromethyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl[(trichloromethyl)sulfonyl]amino]-N-hydroxypropanamide
-
-
2-[benzyl[(trichloromethyl)sulfonyl]amino]propanoic acid
-
-
2-[benzyl[(trifluoromethyl)sulfonyl]amino]-3-methylbutanoic acid
-
-
2-[benzyl[(trifluoromethyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
-
2-[benzyl[(trifluoromethyl)sulfonyl]amino]-N-hydroxypropanamide
-
-
2-[benzyl[(trifluoromethyl)sulfonyl]amino]propanoic acid
-
-
2-[[[2,4,6-(tripropyl)phenyl]sulfonyl](benzyl)amino]propanoic acid
-
-
2-[[[3-(benzyloxycarbonylamino)phenyl]sulfonyl](benzyl)amino]propanoic acid
-
-
2-[[[4-(acetylamino)phenyl]sulfonyl](benzyl)amino]-N-hydroxypropanamide
-
-
2-[[[4-(acetylamino)phenyl]sulfonyl](benzyl)amino]propanoic acid
-
-
2-[[[4-(benzyloxycarbonylamino)phenyl]sulfonyl](benzyl)amino]propanoic acid
-
-
2-[[[4-(methoxy)phenyl]sulfonyl](benzyl)amino]propanoic acid
-
-
3-[(2-chlorobenzyl)[(1S)-2-(hydroxyamino)-1-methyl-2-oxoethyl]sulfamoyl]benzoic acid
-
-
3-[benzyl-(1-carboxy-ethyl)-sulfamoyl]-benzoic acid
-
-
3-[Benzyl-(1-hydrazinocarbonyl-2-methyl-propyl)-sulfamoyl]-N-hydroxy-benzamide
-
-
3-[benzyl-(1-hydroxycarbamoyl-ethyl)-sulfamoyl]-N-hydroxy-benzamide
-
-
3-[[(1S)-1-carboxyethyl](2-chlorobenzyl)sulfamoyl]benzoic acid
-
-
4-[(2-chlorobenzyl)[(1S)-2-(hydroxyamino)-1-methyl-2-oxoethyl]sulfamoyl]benzoic acid
-
-
4-[benzyl-(1-carboxy-ethyl)-sulfamoyl]-benzoic acid
-
-
4-[Benzyl-(1-hydrazinocarbonyl-2-methyl-propyl)-sulfamoyl]-N-hydroxy-benzamide
-
-
4-[benzyl-(1-hydroxycarbamoyl-ethyl)-sulfamoyl]-N-hydroxy-benzamide
-
-
4-[[(1S)-1-carboxyethyl](2-chlorobenzyl)sulfamoyl]benzoic acid
-
-
8-hydroxyquinoline
-
-
alpha,alpha-dipyridyl
-
-
batimastat
-
i.e. BB-94
BAY 12-9566
-
-
diphosphate
-
-
erucic acid
-
IC50: 0.415 mM
glutathione
Guanidine-HCl
-
-
heptadecanoic acid
-
IC50: 0.03 mM
HS-CH2-CH2-CO-Pro-(N-methyl)Ala
Empedobacter collagenolyticum
-
-
HS-CH2-CH2-CO-Pro-(N-methyl)Leu
Empedobacter collagenolyticum
-
-
HS-CH2-CH2-CO-Pro-(N-methyl)Nle
Empedobacter collagenolyticum
-
-
i-C5H11-PO(OH)-Gly-Pro-Ala
-
-
-
isoamyl-phosphonyl-Gly-Pro-Ala
peptidomimetic inhibitor, binds to the edge strand in an antiparallel orientation
L-cysteine
-
-
L-histidine
-
-
linoleic acid
-
IC50: 0.375 mM
linolenic acid
-
IC50: 0.46 mM
marimastat
-
i.e. BB-2516
myristic acid
-
IC50: 0.27 mM
N-(2-chlorobenzyl)-N-(dimethylsulfamoyl)-L-alanine
-
-
N-(2-chlorobenzyl)-N-(methylsulfonyl)-L-alanine
-
-
N-(2-chlorobenzyl)-N-(naphthalen-1-ylcarbamoyl)-L-alanine
-
-
N-(2-chlorobenzyl)-N-(naphthalen-1-ylsulfonyl)-L-alanine
-
-
N-(2-chlorobenzyl)-N-(naphthalen-2-ylsulfonyl)-L-alanine
-
-
N-(2-chlorobenzyl)-N-(phenylsulfonyl)-L-alanine
-
-
N-(2-chlorobenzyl)-N-(thiophen-2-ylsulfonyl)-L-alanine
-
-
N-(2-chlorobenzyl)-N-[(2,4,6-trimethylphenyl)sulfonyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[(2,4-difluorophenyl)carbamoyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[(2,4-dinitrophenyl)sulfanyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[(2,5-dichlorophenyl)sulfonyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[(2-nitrophenyl)sulfanyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[(2-nitrophenyl)sulfonyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[(3,4-dichlorophenyl)carbamoyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[(3,5-dichloro-2-hydroxyphenyl)sulfonyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[(3-chloro-4-nitrophenyl)sulfonyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[(3-chlorophenyl)carbamoyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[(3-nitrophenyl)sulfonyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[(4-bromophenyl)sulfonyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[(4-chlorophenyl)carbamoyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[(4-chlorophenyl)sulfonyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[(4-fluorophenyl)carbamoyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[(4-fluorophenyl)sulfonyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[(4-iodophenyl)sulfonyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[(4-methoxyphenyl)sulfonyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[(4-methylphenyl)sulfonyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[(4-nitrophenyl)sulfanyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[(4-nitrophenyl)sulfonyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[(heptadecafluorooctyl)sulfonyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[(nonafluorobutyl)sulfonyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[(trichloromethyl)sulfonyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[(trifluoromethyl)sulfonyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[[(2-methylphenyl)sulfonyl]carbamoyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[[(4-chlorophenyl)sulfonyl]carbamoyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[[(4-fluorophenyl)sulfonyl]carbamoyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[[(4-methylphenyl)sulfonyl]carbamoyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[[3-(trifluoromethyl)phenyl]sulfonyl]-L-alanine
-
-
N-(2-chlorobenzyl)-N-[[5-(dimethylamino)naphthalen-1-yl]sulfonyl]-L-alanine
-
-
N-(benzylsulfonyl)-N-(2-chlorobenzyl)-L-alanine
-
-
N-([(2-chlorobenzyl)[(1S)-2-(hydroxyamino)-1-methyl-2-oxoethyl]amino]methyl)benzamide
-
-
N-([3-[(tert-butoxycarbonyl)amino]-4-methoxyphenyl]sulfonyl)-N-(2-chlorobenzyl)-L-alanine
-
-
N-([3-[(tert-butoxycarbonyl)amino]phenyl]sulfonyl)-N-(2-chlorobenzyl)-L-alanine
-
-
N-([4-[(tert-butoxycarbonyl)amino]phenyl]sulfonyl)-N-(2-chlorobenzyl)-L-alanine
-
-
N-2-methylphenylsulfonylureido-N-(10,11,dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-glycine
-
-
N-2-methylphenylsulfonylureido-N-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-glycine hydroxamate
-
-
N-2-methylphenylsulfonylureido-N-(5H-dibenzo[a,d]cyclohepten-5-yl)-glycine
-
-
N-2-methylphenylsulfonylureido-N-(5H-dibenzo[a,d]cyclohepten-5-yl)-glycine hydroxamate
-
-
N-2-methylphenylsulfonylureido-N-[(10,11,dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine
-
-
N-2-methylphenylsulfonylureido-N-[(10,11,dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine
-
-
N-2-methylphenylsulfonylureido-N-[(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine hydroxamate
-
-
N-2-methylphenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine
-
-
N-2-methylphenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine
-
-
N-2-methylphenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine hydroxamate
-
-
N-4-chlorophenylsulfonylureido-N-(10,11,dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-glycine
-
-
N-4-chlorophenylsulfonylureido-N-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-glycine hydroxamate
-
-
N-4-chlorophenylsulfonylureido-N-(5H-dibenzo[a,d]cyclohepten-5-yl)-glycine
-
-
N-4-chlorophenylsulfonylureido-N-(5H-dibenzo[a,d]cyclohepten-5-yl)-glycine hydroxamate
-
-
N-4-chlorophenylsulfonylureido-N-[(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine hydroxamate
-
-
N-4-chlorophenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine
-
-
N-4-chlorophenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine
-
-
N-4-chlorophenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine hydroxamate
-
-
N-4-fluorophenylsulfonylureido-N-(10,11,dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-glycine
-
-
N-4-fluorophenylsulfonylureido-N-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-glycine hydroxamate
-
-
N-4-fluorophenylsulfonylureido-N-(5H-dibenzo[a,d]cyclohepten-5-yl)-glycine
-
-
N-4-fluorophenylsulfonylureido-N-(5H-dibenzo[a,d]cyclohepten-5-yl)-glycine hydroxamate
-
-
N-4-fluorophenylsulfonylureido-N-[(10,11,dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine
-
-
N-4-fluorophenylsulfonylureido-N-[(10,11,dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine
-
-
N-4-fluorophenylsulfonylureido-N-[(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine hydroxamate
-
-
N-4-fluorophenylsulfonylureido-N-[(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine hydroxamate
-
-
N-4-fluorophenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine
-
-
N-4-fluorophenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine hydroxamate
-
-
N-4-fluorophenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine
-
-
N-4-fluorophenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine hydroxamate
-
-
N-4-methylphenylsulfonylureido-N-(10,11,dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-glycine
-
-
N-4-methylphenylsulfonylureido-N-(5H-dibenzo[a,d]cyclohepten-5-yl)-glycine
-
-
N-4-methylphenylsulfonylureido-N-(5H-dibenzo[a,d]cyclohepten-5-yl)-glycine hydroxamate
-
-
N-4-methylphenylsulfonylureido-N-[(10,11,dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine
-
-
N-4-methylphenylsulfonylureido-N-[(10,11,dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine
-
-
N-4-methylphenylsulfonylureido-N-[(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine hydroxamate
-
-
N-4-methylphenylsulfonylureido-N-[(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine hydroxamate
-
-
N-4-methylphenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine
-
-
N-4-methylphenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine hydroxamate
-
-
N-4-methylphenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine
-
-
N-4-methylphenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine hydroxamate
-
-
N-etyhlmaleimide
-
-
N-phenylsulfonylureido-N-(5H-dibenzo[a,d]cyclohepten-5-yl)-glycine
-
-
N-phenylsulfonylureido-N-(5H-dibenzo[a,d]cyclohepten-5-yl)-glycine hydroxamate
-
-
N-phenylsulfonylureido-N-[(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine hydroxamate
-
-
N-phenylsulfonylureido-N-[(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine hydroxamate
-
-
N-phenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine
-
-
N-phenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine hydroxamate
-
-
N-phenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine
-
-
N-phenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine hydroxamate
-
-
N-[[4-(acetylamino)phenyl]sulfonyl]-N-(2-chlorobenzyl)-L-alanine
-
-
N2(2-chlorobenzyl)-N-hydroxy-N2-[(trifluoromethyl)sulfonyl]-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N-hydroxy-N2-(naphthalen-1-ylcarbamoyl)-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N-hydroxy-N2-(naphthalen-1-ylsulfonyl)-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N-hydroxy-N2-(naphthalen-2-ylsulfonyl)-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N-hydroxy-N2-(phenylsulfonyl)-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N-hydroxy-N2-(quinolin-8-ylsulfonyl)-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N-hydroxy-N2-(thiophen-2-ylsulfonyl)-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N-hydroxy-N2-[(2,4,6-trimethylphenyl)sulfonyl]-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N-hydroxy-N2-[(2,4-dinitrophenyl)sulfanyl]-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N-hydroxy-N2-[(4-methoxyphenyl)sulfonyl]-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N-hydroxy-N2-[(4-nitrophenyl)sulfanyl]-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N-hydroxy-N2-[(nonafluorobutyl)sulfonyl]-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N-hydroxy-N2-[(trichloromethyl)sulfonyl]-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N-hydroxy-N2-[[3-(trifluoromethyl)phenyl]sulfonyl]-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N2-(dimethylsulfamoyl)-N-hydroxy-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N2-[(2,4-difluorophenyl)carbamoyl]-N-hydroxy-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N2-[(2,5-dichlorophenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N2-[(2-nitrophenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N2-[(3,4-dichlorophenyl)carbamoyl]-N-hydroxy-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N2-[(3,5-dichloro-2-hydroxyphenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N2-[(3-chloro-4-nitrophenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N2-[(3-chlorophenyl)carbamoyl]-N-hydroxy-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N2-[(3-nitrophenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N2-[(4-bromophenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N2-[(4-chlorophenyl)carbamoyl]-N-hydroxy-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N2-[(4-chlorophenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N2-[(4-fluorophenyl)carbamoyl]-N-hydroxy-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N2-[(4-fluorophenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N2-[(4-iodophenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N2-[(4-methylphenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N2-[(4-nitrophenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N2-[(heptadecafluorooctyl)sulfonyl]-N-hydroxy-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N2-[[(2-methylphenyl)sulfonyl]carbamoyl]-N-hydroxy-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N2-[[(4-chlorophenyl)sulfonyl]carbamoyl]-N-hydroxy-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N2-[[(4-fluorophenyl)sulfonyl]carbamoyl]-N-hydroxy-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N2-[[(4-methylphenyl)sulfonyl]carbamoyl]-N-hydroxy-L-alaninamide
-
-
N2-(2-chlorobenzyl)-N2-[[5-(dimethylamino)naphthalen-1-yl]sulfonyl]-N-hydroxy-L-alaninamide
-
-
N2-(benzylsulfonyl)-N2-(2-chlorobenzyl)-N-hydroxy-L-alaninamide
-
-
N2-chlorobenzyl)-N-hydroxy-N2-(methylsulfonyl)-L-alaninamide
-
-
N2-[[4-(acetylamino)phenyl]sulfonyl]-N2-(2-chlorobenzyl)-N-hydroxy-L-alaninamide
-
-
nonadecanoic acid
-
0.045 mM
oleic acid
-
IC50: 0.46 mM
p-O2NC6H4CH2CH2PO(OH)Gly-Pro-2-aminohexanoic acid
-
-
-
palmitic acid
-
IC50: 0.035 mM
palmitoleic acid
-
IC50: 0.405 mM
pentadecanoic acid
-
IC50: 0.125 mM
Phosphate buffer
-
-
-
Pro6-Gly-Pro-Gly
-
-
-
Pro6-Gly-Pro-Gly-H
-
-
-
SDS
-
surface active substance
Sodiumthioglycolate
-
-
stearic acid
-
IC50: 0.03 mM
Tannic acid
-
competitive, almost complete inhibition. Pretreatment of collagen fibers with tannic acid results in polymerization and complex formation
tert-butyl (3-[(2-chlorobenzyl)[(1S)-2-(hydroxyamino)-1-methyl-2-oxoethyl]sulfamoyl]phenyl)carbamate
-
-
tert-butyl (4-[(2-chlorobenzyl)[(1S)-2-(hydroxyamino)-1-methyl-2-oxoethyl]sulfamoyl]phenyl)carbamate
-
-
tert-butyl (5-[(2-chlorobenzyl)[(1S)-2-(hydroxyamino)-1-methyl-2-oxoethyl]sulfamoyl]-2-methoxyphenyl)carbamate
-
-
trocade
-
i.e. RO-22-3555
[3-[benzyl-(1-hydroxycarbamoyl-ethyl)-sulfamoyl]-phenyl]-carbamic acid tert-butyl ester
-
-
[4-[benzyl-(1-hydroxycarbamoyl-ethyl)-sulfamoyl]-phenyl]-carbamic acid tert-butyl ester
-
-
[5-[benzyl-(3-hydroxy-1-methyl-2-oxo-propyl)-sulfamoyl]-2-methoxy-phenyl]-carbamic acid tert-butyl ester
-
-
additional information
-
ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-mercaptoethanol
-
activates
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1.06
2-furanacryloyl-Leu-Gly-Pro-Ala
-
-
0.71
Carbobenzoxy-Gly-Pro-Gly-Gly-Pro-Ala
-
-
0.269 - 1.26
furylacryloyl-Leu-Gly-Pro-Ala
0.555
N-[3-(2-furyl) acryloyl]-L-Leu-Gly-L-Pro-L-Ala
-
pH 7.5, 25°C
additional information
additional information
-
TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.092 - 15.9
furylacryloyl-Leu-Gly-Pro-Ala
Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0056
2-(1-benzyl-3-naphthalen-1-yl-ureido)-3-methyl-butyric acid
-
pH 7.5, 25°C
0.000012
2-(1-benzyl-3-naphthalen-1-yl-ureido)-N-hydroxy-3-methyl-butyramide
-
pH 7.5, 25°C
0.000006
2-(3-benzoyl-1-benzyl-thioureido)-N-hydroxy-3-methyl-butyramide
-
pH 7.5, 25°C
0.0074
2-(benzyl[[(2,4-difluorophenyl)amino]carbonyl]amino)-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000021
2-(benzyl[[(2,4-difluorophenyl)amino]carbonyl]amino)-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.000024
2-(benzyl[[(2,4-difluorophenyl)amino]carbonyl]amino)-N-hydroxypropanamide
-
pH 7.5, 25°C
0.0073
2-(benzyl[[(2,4-difluorophenyl)amino]carbonyl]amino)propanoic acid
-
pH 7.5, 25°C
0.0042
2-(benzyl[[(3,4-dichlorophenyl)amino]carbonyl]amino)-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000009
2-(benzyl[[(3,4-dichlorophenyl)amino]carbonyl]amino)-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.00001
2-(benzyl[[(3,4-dichlorophenyl)amino]carbonyl]amino)-N-hydroxypropanamide
-
pH 7.5, 25°C
0.0048
2-(benzyl[[(3,4-dichlorophenyl)amino]carbonyl]amino)propanoic acid
-
pH 7.5, 25°C
0.01
2-(benzyl[[(3-chlorophenyl)amino]carbonyl]amino)-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000033
2-(benzyl[[(3-chlorophenyl)amino]carbonyl]amino)-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.000034
2-(benzyl[[(3-chlorophenyl)amino]carbonyl]amino)-N-hydroxypropanamide
-
pH 7.5, 25°C
0.011
2-(benzyl[[(3-chlorphenyl)amino]carbonyl]amino)propanoic acid
-
pH 7.5, 25°C
0.0083
2-(benzyl[[(4-chlorophenyl)amino]carbonyl]amino)-3-methylbutanoic acid
-
pH 7.5, 25°C
0.00003
2-(benzyl[[(4-chlorophenyl)amino]carbonyl]amino)-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.00003
2-(benzyl[[(4-chlorophenyl)amino]carbonyl]amino)-N-hydroxypropanamide
-
pH 7.5, 25°C
0.0088
2-(benzyl[[(4-chlorphenyl)amino]carbonyl]amino)propanoic acid
-
pH 7.5, 25°C
0.0091
2-(benzyl[[(4-fluorophenyl)amino]carbonyl]amino)-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000031
2-(benzyl[[(4-fluorophenyl)amino]carbonyl]amino)-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.000033
2-(benzyl[[(4-fluorophenyl)amino]carbonyl]amino)-N-hydroxypropanamide
-
pH 7.5, 25°C
0.01
2-(benzyl[[(4-fluorophenyl)amino]carbonyl]amino)propanoic acid
-
pH 7.5, 25°C
0.000006
2-(benzyl[[3-(trifluoromethyl)phenyl]sulfonyl]amino)-N-hydroxypropanamide
-
pH 7.5, 25°C
0.0006
2-(benzyl[[3-(trifluoromethyl)phenyl]sulfonyl]amino)propanoic acid
-
pH 7.5, 25°C
0.0036
2-[benzyl(1-naphthylsulfonyl)amino]propanoic acid
-
pH 7.5, 25°C
0.0014
2-[benzyl(2-naphthylsulfonyl)amino]propanoic acid
-
pH 7.5, 25°C
0.002
2-[benzyl(5-methylnaphthalene-1-sulfonyl)amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.015
2-[benzyl(benzylsulfonyl)amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.00004
2-[benzyl(benzylsulfonyl)amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.000043
2-[benzyl(benzylsulfonyl)amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.017
2-[benzyl(benzylsulfonyl)amino]propanoic acid
-
pH 7.5, 25°C
0.018
2-[benzyl(methylsulfonyl)amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000103
2-[benzyl(methylsulfonyl)amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.02
2-[benzyl(methylsulfonyl)amino]propanoic acid
-
pH 7.5, 25°C
0.0033
2-[benzyl(naphthalene-1-sulfonyl)amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.0014
2-[benzyl(naphthalene-2-sulfonyl)amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000005
2-[benzyl(phenylcarbonothioyl)amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.02
2-[benzyl(phenylsulfonyl)amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000054
2-[benzyl(phenylsulfonyl)amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.000051
2-[benzyl(phenylsulfonyl)amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.022
2-[benzyl(phenylsulfonyl)amino]propanoic acid
-
pH 7.5, 25°C
0.0021
2-[benzyl(thien-2-ylsulfonyl)amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.00001
2-[benzyl(thien-2-ylsulfonyl)amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.000011
2-[benzyl(thien-2-ylsulfonyl)amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.0024
2-[benzyl(thien-2-ylsulfonyl)amino]propanoic acid
-
pH 7.5, 25°C
0.008
2-[benzyl([[(2-methylphenyl)sulfonyl]amino]carbonyl)amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000012
2-[benzyl([[(2-methylphenyl)sulfonyl]amino]carbonyl)amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.000017
2-[benzyl([[(2-methylphenyl)sulfonyl]amino]carbonyl)amino]-N-hydroxyacetamide
-
pH 7.5, 25°C
0.000014
2-[benzyl([[(2-methylphenyl)sulfonyl]amino]carbonyl)amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.009
2-[benzyl([[(2-methylphenyl)sulfonyl]amino]carbonyl)amino]propanoic acid
-
pH 7.5, 25°C
0.0069
2-[benzyl([[(4-chlorophenyl)sulfonyl]amino]carbonyl)amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000015
2-[benzyl([[(4-chlorophenyl)sulfonyl]amino]carbonyl)amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.000015
2-[benzyl([[(4-chlorophenyl)sulfonyl]amino]carbonyl)amino]-N-hydroxyacetamide
-
pH 7.5, 25°C
0.000015
2-[benzyl([[(4-chlorophenyl)sulfonyl]amino]carbonyl)amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.0064
2-[benzyl([[(4-chlorophenyl)sulfonyl]amino]carbonyl)amino]propanoic acid
-
pH 7.5, 25°C
0.0075
2-[benzyl([[(4-fluorophenyl)sulfonyl]amino]carbonyl)amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000019
2-[benzyl([[(4-fluorophenyl)sulfonyl]amino]carbonyl)amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.000021
2-[benzyl([[(4-fluorophenyl)sulfonyl]amino]carbonyl)amino]-N-hydroxyacetamide
-
pH 7.5, 25°C
0.000018
2-[benzyl([[(4-fluorophenyl)sulfonyl]amino]carbonyl)amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.0082
2-[benzyl([[(4-fluorophenyl)sulfonyl]amino]carbonyl)amino]propanoic acid
-
pH 7.5, 25°C
0.007
2-[benzyl([[(4-methylphenyl)sulfonyl]amino]carbonyl)amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000013
2-[benzyl([[(4-methylphenyl)sulfonyl]amino]carbonyl)amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.000016
2-[benzyl([[(4-methylphenyl)sulfonyl]amino]carbonyl)amino]-N-hydroxyacetamide
-
pH 7.5, 25°C
0.000015
2-[benzyl([[(4-methylphenyl)sulfonyl]amino]carbonyl)amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.0071
2-[benzyl([[(4-methylphenyl)sulfonyl]amino]carbonyl)amino]propanoic acid
-
pH 7.5, 25°C
0.000019
2-[benzyl-(2,4,6-tripropyl-benzenesulfonyl)-amino]-N-hydroxy-propionamide
-
pH 7.5, 25°C
0.000008
2-[benzyl-(3,5-dichloro-2-hydroxy-benzenesulfonyl)-amino]-N-hydroxy-propionamide
-
pH 7.5, 25°C
0.003
2-[benzyl-(3,5-dichloro-2-hydroxy-benzenesulfonyl)-amino]-propionic acid
-
pH 7.5, 25°C
0.0031
2-[benzyl-(3-tert-butoxycarbonylamino-4-methoxy-benzenesulfonyl)-amino]-propionic acid
-
pH 7.5, 25°C
0.00001
2-[benzyl-(5-dimethylamino-naphthalene-1-sulfonyl)-amino]-N-hydroxy-propionamide
-
pH 7.5, 25°C
0.0025
2-[benzyl-(5-dimethylamino-naphthalene-1-sulfonyl)-amino]-propionic acid
-
pH 7.5, 25°C
0.000008
2-[Benzyl-(5-methylnaphthalene-1-sulfonyl)-amino]-N-hydroxy-3-methyl-butyramide
-
pH 7.5, 25°C
0.0019
2-[benzyl-(heptadecafluorooctane-1-sulfonyl)-amino]-3-methyl-butyric acid
-
pH 7.5, 25°C
0.000008
2-[Benzyl-(heptadecafluorooctane-1-sulfonyl)-amino]-N-hydroxy-3-methyl-butyramide
-
pH 7.5, 25°C
0.000009
2-[Benzyl-(naphthalene-1-sulfonyl)-amino]-N-hydroxy-3-methyl-butyramide
-
pH 7.5, 25°C
0.00001
2-[benzyl-(naphthalene-1-sulfonyl)-amino]-N-hydroxy-propionamide
-
pH 7.5, 25°C
0.000006
2-[Benzyl-(naphthalene-2-sulfonyl)-amino]-N-hydroxy-3-methyl-butyramide
-
pH 7.5, 25°C
0.000009
2-[benzyl-(naphthalene-2-sulfonyl)-amino]-N-hydroxy-propionamide
-
pH 7.5, 25°C
0.00004
2-[benzyl-(toluene-4-sulfonyl)-amino]-N-hydroxy-propionamide
-
pH 7.5, 25°C
0.000011
2-[benzyl[(1-naphthylamino)carbonyl]amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.0051
2-[benzyl[(1-naphthylamino)carbonyl]amino]propanoic acid
-
pH 7.5, 25°C
0.0061
2-[benzyl[(2,4,6-trimethylphenyl)sulfonyl]amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000018
2-[benzyl[(2,4,6-trimethylphenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.007
2-[benzyl[(2,4-dinitrophenyl)thio]amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000008
2-[benzyl[(2,4-dinitrophenyl)thio]amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.00001
2-[benzyl[(2,4-dinitrophenyl)thio]amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.0071
2-[benzyl[(2,4-dinitrophenyl)thio]amino]propanoic acid
-
pH 7.5, 25°C
0.004
2-[benzyl[(2,5-dichlorophenyl)sulfonyl]amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000011
2-[benzyl[(2,5-dichlorophenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.000014
2-[benzyl[(2,5-dichlorophenyl)sulfonyl]amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.0047
2-[benzyl[(2,5-dichlorophenyl)sulfonyl]amino]propanoic acid
-
pH 7.5, 25°C
0.0053
2-[benzyl[(2-nitrophenyl)sulfonyl]amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000018
2-[benzyl[(2-nitrophenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.000021
2-[benzyl[(2-nitrophenyl)sulfonyl]amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.0059
2-[benzyl[(2-nitrophenyl)sulfonyl]amino]propanoic acid
-
pH 7.5, 25°C
0.0062
2-[benzyl[(2-nitrophenyl)thio]amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000012
2-[benzyl[(2-nitrophenyl)thio]amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.0032
2-[benzyl[(3,5-dichloro-2-hydroxyphenyl)sulfonyl]amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000007
2-[benzyl[(3,5-dichloro-2-hydroxyphenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.0033
2-[benzyl[(3-butyloxycarbonylamino-4-methoxyphenyl)sulfonyl]amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000007
2-[benzyl[(3-butyloxycarbonylamino-4-methoxyphenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.0023
2-[benzyl[(3-butyloxycarbonylaminophenyl)sulfonyl]amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000007
2-[benzyl[(3-butyloxycarbonylaminophenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.0045
2-[benzyl[(3-carboxyphenyl)sulfonyl]amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.003
2-[benzyl[(3-chloro-4-nitrophenyl)sulfonyl]amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000011
2-[benzyl[(3-chloro-4-nitrophenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.000011
2-[benzyl[(3-chloro-4-nitrophenyl)sulfonyl]amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.003
2-[benzyl[(3-chloro-4-nitrophenyl)sulfonyl]amino]propanoic acid
-
pH 7.5, 25°C
0.0051
2-[benzyl[(3-nitrophenyl)sulfonyl]amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000011
2-[benzyl[(3-nitrophenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.000012
2-[benzyl[(3-nitrophenyl)sulfonyl]amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.0052
2-[benzyl[(3-nitrophenyl)sulfonyl]amino]propanoic acid
-
pH 7.5, 25°C
0.000012
2-[benzyl[(3-nitrophenyl)thio]amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.0063
2-[benzyl[(3-nitrophenyl)thio]amino]propanoic acid
-
pH 7.5, 25°C
0.0006
2-[benzyl[(3-trifluoromethylphenyl)sulfonyl]amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000006
2-[benzyl[(3-trifluoromethylphenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.0035
2-[benzyl[(4-acetamidophenyl)sulfonyl]amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.00001
2-[benzyl[(4-acetamidophenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.01
2-[benzyl[(4-bromophenyl)sulfonyl]amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000036
2-[benzyl[(4-bromophenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.000037
2-[benzyl[(4-bromophenyl)sulfonyl]amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.011
2-[benzyl[(4-bromophenyl)sulfonyl]amino]propanoic acid
-
pH 7.5, 25°C
0.0024
2-[benzyl[(4-butyloxycarbonylaminophenyl)sulfonyl]amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000008
2-[benzyl[(4-butyloxycarbonylaminophenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.0024
2-[benzyl[(4-carboxyphenyl)sulfonyl]amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.011
2-[benzyl[(4-chlorophenyl)sulfonyl]amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000044
2-[benzyl[(4-chlorophenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.000044
2-[benzyl[(4-chlorophenyl)sulfonyl]amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.013
2-[benzyl[(4-chlorophenyl)sulfonyl]amino]propanoic acid
-
pH 7.5, 25°C
0.012
2-[benzyl[(4-fluorophenyl)sulfonyl]amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000042
2-[benzyl[(4-fluorophenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.000045
2-[benzyl[(4-fluorophenyl)sulfonyl]amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.013
2-[benzyl[(4-fluorophenyl)sulfonyl]amino]propanoic acid
-
pH 7.5, 25°C
0.01
2-[benzyl[(4-iodophenyl)sulfonyl]amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.00003
2-[benzyl[(4-iodophenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.000032
2-[benzyl[(4-iodophenyl)sulfonyl]amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.01
2-[benzyl[(4-iodophenyl)sulfonyl]amino]propanoic acid
-
pH 7.5, 25°C
0.0063
2-[benzyl[(4-methoxyphenyl)sulfonyl]amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000017
2-[benzyl[(4-methoxyphenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.00002
2-[benzyl[(4-methoxyphenyl)sulfonyl]amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.015
2-[benzyl[(4-methylphenyl)sulfonyl]amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000033
2-[benzyl[(4-methylphenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.016
2-[benzyl[(4-methylphenyl)sulfonyl]amino]propanoic acid
-
pH 7.5, 25°C
0.005
2-[benzyl[(4-nitrophenyl)sulfonyl]amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000015
2-[benzyl[(4-nitrophenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.000015
2-[benzyl[(4-nitrophenyl)sulfonyl]amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.0055
2-[benzyl[(4-nitrophenyl)sulfonyl]amino]propanoic acid
-
pH 7.5, 25°C
0.006
2-[benzyl[(4-nitrophenyl)thio]amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000013
2-[benzyl[(4-nitrophenyl)thio]amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.000015
2-[benzyl[(4-nitrophenyl)thio]amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.006
2-[benzyl[(4-nitrophenyl)thio]amino]propanoic acid
-
pH 7.5, 25°C
0.041
2-[benzyl[(dimethylamino)sulfonyl]amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000065
2-[benzyl[(dimethylamino)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.000068
2-[benzyl[(dimethylamino)sulfonyl]amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.04
2-[benzyl[(dimethylamino)sulfonyl]amino]propanoic acid
-
pH 7.5, 25°C
0.0018
2-[benzyl[(heptadecafluorooctyl)sulfonyl]amino]propanoic acid
-
pH 7.5, 25°C
0.000007
2-[benzyl[(heptadecfluorooctyl)sulfonyl]amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.0032
2-[benzyl[(nonafluorobutyl)sulfonyl]amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.00001
2-[benzyl[(nonafluorobutyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.000012
2-[benzyl[(nonafluorobutyl)sulfonyl]amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.0031
2-[benzyl[(nonafluorobutyl)sulfonyl]amino]propanoic acid
-
pH 7.5, 25°C
0.0004
2-[benzyl[(pentafluorophenyl)sulfonyl]amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000005
2-[benzyl[(pentafluorophenyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.000006
2-[benzyl[(pentafluorophenyl)sulfonyl]amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.0005
2-[benzyl[(pentafluorophenyl)sulfonyl]amino]propanoic acid
-
pH 7.5, 25°C
0.0056
2-[benzyl[(trichloromethyl)sulfonyl]amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000052
2-[benzyl[(trichloromethyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.00005
2-[benzyl[(trichloromethyl)sulfonyl]amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.0055
2-[benzyl[(trichloromethyl)sulfonyl]amino]propanoic acid
-
pH 7.5, 25°C
0.0033
2-[benzyl[(trifluoromethyl)sulfonyl]amino]-3-methylbutanoic acid
-
pH 7.5, 25°C
0.000047
2-[benzyl[(trifluoromethyl)sulfonyl]amino]-N-hydroxy-3-methylbutanamide
-
pH 7.5, 25°C
0.000048
2-[benzyl[(trifluoromethyl)sulfonyl]amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.0036
2-[benzyl[(trifluoromethyl)sulfonyl]amino]propanoic acid
-
pH 7.5, 25°C
0.0068
2-[[[2,4,6-(tripropyl)phenyl]sulfonyl](benzyl)amino]propanoic acid
-
pH 7.5, 25°C
0.0022
2-[[[3-(benzyloxycarbonylamino)phenyl]sulfonyl](benzyl)amino]propanoic acid
-
pH 7.5, 25°C
0.000012
2-[[[4-(acetylamino)phenyl]sulfonyl](benzyl)amino]-N-hydroxypropanamide
-
pH 7.5, 25°C
0.0036
2-[[[4-(acetylamino)phenyl]sulfonyl](benzyl)amino]propanoic acid
-
pH 7.5, 25°C
0.0027
2-[[[4-(benzyloxycarbonylamino)phenyl]sulfonyl](benzyl)amino]propanoic acid
-
pH 7.5, 25°C
0.0062
2-[[[4-(methoxy)phenyl]sulfonyl](benzyl)amino]propanoic acid
-
pH 7.5, 25°C
0.000008
3-[(2-chlorobenzyl)[(1S)-2-(hydroxyamino)-1-methyl-2-oxoethyl]sulfamoyl]benzoic acid
-
pH 7.5, 25°C
0.0045
3-[benzyl-(1-carboxy-ethyl)-sulfamoyl]-benzoic acid
-
pH 7.5, 25°C
0.000009
3-[Benzyl-(1-hydrazinocarbonyl-2-methyl-propyl)-sulfamoyl]-N-hydroxy-benzamide
-
pH 7.5, 25°C
0.000009
3-[benzyl-(1-hydroxycarbamoyl-ethyl)-sulfamoyl]-N-hydroxy-benzamide
-
pH 7.5, 25°C
0.0041
3-[[(1S)-1-carboxyethyl](2-chlorobenzyl)sulfamoyl]benzoic acid
-
pH 7.5, 25°C
0.000007
4-[(2-chlorobenzyl)[(1S)-2-(hydroxyamino)-1-methyl-2-oxoethyl]sulfamoyl]benzoic acid
-
pH 7.5, 25°C
0.0029
4-[benzyl-(1-carboxy-ethyl)-sulfamoyl]-benzoic acid
-
pH 7.5, 25°C
0.000008
4-[Benzyl-(1-hydrazinocarbonyl-2-methyl-propyl)-sulfamoyl]-N-hydroxy-benzamide
-
pH 7.5, 25°C
0.000007
4-[benzyl-(1-hydroxycarbamoyl-ethyl)-sulfamoyl]-N-hydroxy-benzamide
-
pH 7.5, 25°C
0.0038
4-[[(1S)-1-carboxyethyl](2-chlorobenzyl)sulfamoyl]benzoic acid
-
pH 7.5, 25°C
0.016
i-C5H11-PO(OH)-Gly-Pro-Ala
-
pH 7.5, 25°C
-
0.04
N-(2-chlorobenzyl)-N-(dimethylsulfamoyl)-L-alanine
-
pH 7.5, 25°C
0.021
N-(2-chlorobenzyl)-N-(methylsulfonyl)-L-alanine
-
pH 7.5, 25°C
0.005
N-(2-chlorobenzyl)-N-(naphthalen-1-ylcarbamoyl)-L-alanine
-
pH 7.5, 25°C
0.0016
N-(2-chlorobenzyl)-N-(naphthalen-1-ylsulfonyl)-L-alanine
-
pH 7.5, 25°C
0.0015
N-(2-chlorobenzyl)-N-(naphthalen-2-ylsulfonyl)-L-alanine
-
pH 7.5, 25°C
0.0004 - 0.024
N-(2-chlorobenzyl)-N-(phenylsulfonyl)-L-alanine
0.002 - 0.0024
N-(2-chlorobenzyl)-N-(thiophen-2-ylsulfonyl)-L-alanine
0.0068
N-(2-chlorobenzyl)-N-[(2,4,6-trimethylphenyl)sulfonyl]-L-alanine
-
pH 7.5, 25°C
0.0055
N-(2-chlorobenzyl)-N-[(2,4-difluorophenyl)carbamoyl]-L-alanine
-
pH 7.5, 25°C
0.0041
N-(2-chlorobenzyl)-N-[(2,5-dichlorophenyl)sulfonyl]-L-alanine
-
pH 7.5, 25°C
0.0049
N-(2-chlorobenzyl)-N-[(2-nitrophenyl)sulfonyl]-L-alanine
-
pH 7.5, 25°C
0.0058
N-(2-chlorobenzyl)-N-[(3,4-dichlorophenyl)carbamoyl]-L-alanine
-
pH 7.5, 25°C
0.0024
N-(2-chlorobenzyl)-N-[(3,5-dichloro-2-hydroxyphenyl)sulfonyl]-L-alanine
-
pH 7.5, 25°C
0.0031
N-(2-chlorobenzyl)-N-[(3-chloro-4-nitrophenyl)sulfonyl]-L-alanine
-
pH 7.5, 25°C
0.0076
N-(2-chlorobenzyl)-N-[(3-chlorophenyl)carbamoyl]-L-alanine
-
pH 7.5, 25°C
0.005
N-(2-chlorobenzyl)-N-[(3-nitrophenyl)sulfonyl]-L-alanine
-
pH 7.5, 25°C
0.01
N-(2-chlorobenzyl)-N-[(4-bromophenyl)sulfonyl]-L-alanine
-
pH 7.5, 25°C
0.0068
N-(2-chlorobenzyl)-N-[(4-chlorophenyl)carbamoyl]-L-alanine
-
pH 7.5, 25°C
0.013
N-(2-chlorobenzyl)-N-[(4-chlorophenyl)sulfonyl]-L-alanine
-
pH 7.5, 25°C
0.0074
N-(2-chlorobenzyl)-N-[(4-fluorophenyl)carbamoyl]-L-alanine
-
pH 7.5, 25°C
0.012
N-(2-chlorobenzyl)-N-[(4-fluorophenyl)sulfonyl]-L-alanine
-
pH 7.5, 25°C
0.01
N-(2-chlorobenzyl)-N-[(4-iodophenyl)sulfonyl]-L-alanine
-
pH 7.5, 25°C
0.006
N-(2-chlorobenzyl)-N-[(4-methoxyphenyl)sulfonyl]-L-alanine
-
pH 7.5, 25°C
0.018
N-(2-chlorobenzyl)-N-[(4-methylphenyl)sulfonyl]-L-alanine
-
pH 7.5, 25°C
0.0051
N-(2-chlorobenzyl)-N-[(4-nitrophenyl)sulfonyl]-L-alanine
-
pH 7.5, 25°C
0.0015
N-(2-chlorobenzyl)-N-[(heptadecafluorooctyl)sulfonyl]-L-alanine
-
pH 7.5, 25°C
0.003
N-(2-chlorobenzyl)-N-[(nonafluorobutyl)sulfonyl]-L-alanine
-
pH 7.5, 25°C
0.0052
N-(2-chlorobenzyl)-N-[(trichloromethyl)sulfonyl]-L-alanine
-
pH 7.5, 25°C
0.0033
N-(2-chlorobenzyl)-N-[(trifluoromethyl)sulfonyl]-L-alanine
-
pH 7.5, 25°C
0.004
N-(2-chlorobenzyl)-N-[[(2-methylphenyl)sulfonyl]carbamoyl]-L-alanine
-
pH 7.5, 25°C
0.0034
N-(2-chlorobenzyl)-N-[[(4-chlorophenyl)sulfonyl]carbamoyl]-L-alanine
-
pH 7.5, 25°C
0.0036
N-(2-chlorobenzyl)-N-[[(4-fluorophenyl)sulfonyl]carbamoyl]-L-alanine
-
pH 7.5, 25°C
0.0041
N-(2-chlorobenzyl)-N-[[(4-methylphenyl)sulfonyl]carbamoyl]-L-alanine
-
pH 7.5, 25°C
0.0005
N-(2-chlorobenzyl)-N-[[3-(trifluoromethyl)phenyl]sulfonyl]-L-alanine
-
pH 7.5, 25°C
0.0021
N-(2-chlorobenzyl)-N-[[5-(dimethylamino)naphthalen-1-yl]sulfonyl]-L-alanine
-
pH 7.5, 25°C
0.016
N-(benzylsulfonyl)-N-(2-chlorobenzyl)-L-alanine
-
pH 7.5, 25°C
0.000006
N-([(2-chlorobenzyl)[(1S)-2-(hydroxyamino)-1-methyl-2-oxoethyl]amino]methyl)benzamide
-
pH 7.5, 25°C
0.003
N-([3-[(tert-butoxycarbonyl)amino]-4-methoxyphenyl]sulfonyl)-N-(2-chlorobenzyl)-L-alanine
-
pH 7.5, 25°C
0.0024
N-([3-[(tert-butoxycarbonyl)amino]phenyl]sulfonyl)-N-(2-chlorobenzyl)-L-alanine
-
pH 7.5, 25°C
0.0027
N-([4-[(tert-butoxycarbonyl)amino]phenyl]sulfonyl)-N-(2-chlorobenzyl)-L-alanine
-
pH 7.5, 25°C
0.000189
N-2-methylphenylsulfonylureido-N-(10,11,dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-glycine
-
pH 7.5, 25°C
0.000028
N-2-methylphenylsulfonylureido-N-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-glycine hydroxamate
-
pH 7.5, 25°C
0.00015
N-2-methylphenylsulfonylureido-N-(5H-dibenzo[a,d]cyclohepten-5-yl)-glycine
-
pH 7.5, 25°C
0.000021
N-2-methylphenylsulfonylureido-N-(5H-dibenzo[a,d]cyclohepten-5-yl)-glycine hydroxamate
-
pH 7.5, 25°C
0.000061
N-2-methylphenylsulfonylureido-N-[(10,11,dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine
-
pH 7.5, 25°C
0.000043
N-2-methylphenylsulfonylureido-N-[(10,11,dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine
-
pH 7.5, 25°C
0.00002
N-2-methylphenylsulfonylureido-N-[(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine hydroxamate
-
pH 7.5, 25°C
0.000045
N-2-methylphenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine
-
pH 7.5, 25°C
0.00004
N-2-methylphenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine
-
pH 7.5, 25°C
0.000015
N-2-methylphenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine hydroxamate
-
pH 7.5, 25°C
0.00017
N-4-chlorophenylsulfonylureido-N-(10,11,dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-glycine
-
pH 7.5, 25°C
0.000021
N-4-chlorophenylsulfonylureido-N-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-glycine hydroxamate
-
pH 7.5, 25°C
0.000125
N-4-chlorophenylsulfonylureido-N-(5H-dibenzo[a,d]cyclohepten-5-yl)-glycine
-
pH 7.5, 25°C
0.000014
N-4-chlorophenylsulfonylureido-N-(5H-dibenzo[a,d]cyclohepten-5-yl)-glycine hydroxamate
-
pH 7.5, 25°C
0.000009
N-4-chlorophenylsulfonylureido-N-[(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine hydroxamate
-
pH 7.5, 25°C
0.000026
N-4-chlorophenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine
-
pH 7.5, 25°C
0.000025
N-4-chlorophenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine
-
pH 7.5, 25°C
0.000007
N-4-chlorophenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine hydroxamate
-
pH 7.5, 25°C
0.000163
N-4-fluorophenylsulfonylureido-N-(10,11,dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-glycine
-
pH 7.5, 25°C
0.000018
N-4-fluorophenylsulfonylureido-N-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-glycine hydroxamate
-
pH 7.5, 25°C
0.00014
N-4-fluorophenylsulfonylureido-N-(5H-dibenzo[a,d]cyclohepten-5-yl)-glycine
-
pH 7.5, 25°C
0.000013
N-4-fluorophenylsulfonylureido-N-(5H-dibenzo[a,d]cyclohepten-5-yl)-glycine hydroxamate
-
pH 7.5, 25°C
0.00005
N-4-fluorophenylsulfonylureido-N-[(10,11,dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine
-
pH 7.5, 25°C
0.00006
N-4-fluorophenylsulfonylureido-N-[(10,11,dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine
-
pH 7.5, 25°C
0.000013
N-4-fluorophenylsulfonylureido-N-[(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine hydroxamate
-
pH 7.5, 25°C
0.000007
N-4-fluorophenylsulfonylureido-N-[(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine hydroxamate
-
pH 7.5, 25°C
0.000033
N-4-fluorophenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine
-
pH 7.5, 25°C
0.00001
N-4-fluorophenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine hydroxamate
-
pH 7.5, 25°C
0.000021
N-4-fluorophenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine
-
pH 7.5, 25°C
0.000006
N-4-fluorophenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine hydroxamate
-
pH 7.5, 25°C
0.000165
N-4-methylphenylsulfonylureido-N-(10,11,dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-glycine
-
pH 7.5, 25°C
0.000133
N-4-methylphenylsulfonylureido-N-(5H-dibenzo[a,d]cyclohepten-5-yl)-glycine
-
pH 7.5, 25°C
0.000018
N-4-methylphenylsulfonylureido-N-(5H-dibenzo[a,d]cyclohepten-5-yl)-glycine hydroxamate
-
pH 7.5, 25°C
0.000055
N-4-methylphenylsulfonylureido-N-[(10,11,dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine
-
pH 7.5, 25°C
0.000042
N-4-methylphenylsulfonylureido-N-[(10,11,dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine
-
pH 7.5, 25°C
0.000018
N-4-methylphenylsulfonylureido-N-[(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine hydroxamate
-
pH 7.5, 25°C
0.000019
N-4-methylphenylsulfonylureido-N-[(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine hydroxamate
-
pH 7.5, 25°C
0.00004
N-4-methylphenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine
-
pH 7.5, 25°C
0.000015
N-4-methylphenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine hydroxamate
-
pH 7.5, 25°C
0.000038
N-4-methylphenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine
-
pH 7.5, 25°C
0.000012
N-4-methylphenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine hydroxamate
-
pH 7.5, 25°C
0.000125
N-phenylsulfonylureido-N-(5H-dibenzo[a,d]cyclohepten-5-yl)-glycine
-
pH 7.5, 25°C
0.000016
N-phenylsulfonylureido-N-(5H-dibenzo[a,d]cyclohepten-5-yl)-glycine hydroxamate
-
pH 7.5, 25°C
0.000015
N-phenylsulfonylureido-N-[(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine hydroxamate
-
pH 7.5, 25°C
0.00001
N-phenylsulfonylureido-N-[(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine hydroxamate
-
pH 7.5, 25°C
0.000086
N-phenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine
-
pH 7.5, 25°C
0.000013
N-phenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)ethylene]-glycine hydroxamate
-
pH 7.5, 25°C
0.000035
N-phenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine
-
pH 7.5, 25°C
0.000008
N-phenylsulfonylureido-N-[(5H-dibenzo[a,d]cyclohepten-5-yl)methylen]-glycine hydroxamate
-
pH 7.5, 25°C
0.003
N-[[4-(acetylamino)phenyl]sulfonyl]-N-(2-chlorobenzyl)-L-alanine
-
pH 7.5, 25°C
0.000076
N2(2-chlorobenzyl)-N-hydroxy-N2-[(trifluoromethyl)sulfonyl]-L-alaninamide
-
pH 7.5, 25°C
0.000011
N2-(2-chlorobenzyl)-N-hydroxy-N2-(naphthalen-1-ylcarbamoyl)-L-alaninamide
-
pH 7.5, 25°C
0.000008
N2-(2-chlorobenzyl)-N-hydroxy-N2-(naphthalen-1-ylsulfonyl)-L-alaninamide
-
pH 7.5, 25°C
0.000009
N2-(2-chlorobenzyl)-N-hydroxy-N2-(naphthalen-2-ylsulfonyl)-L-alaninamide
-
pH 7.5, 25°C
0.0000005 - 0.000058
N2-(2-chlorobenzyl)-N-hydroxy-N2-(phenylsulfonyl)-L-alaninamide
0.000007
N2-(2-chlorobenzyl)-N-hydroxy-N2-(quinolin-8-ylsulfonyl)-L-alaninamide
-
pH 7.5, 25°C
0.000011
N2-(2-chlorobenzyl)-N-hydroxy-N2-(thiophen-2-ylsulfonyl)-L-alaninamide
-
pH 7.5, 25°C
0.000017
N2-(2-chlorobenzyl)-N-hydroxy-N2-[(2,4,6-trimethylphenyl)sulfonyl]-L-alaninamide
-
pH 7.5, 25°C
0.000011
N2-(2-chlorobenzyl)-N-hydroxy-N2-[(2,4-dinitrophenyl)sulfanyl]-L-alaninamide
-
pH 7.5, 25°C
0.000022
N2-(2-chlorobenzyl)-N-hydroxy-N2-[(4-methoxyphenyl)sulfonyl]-L-alaninamide
-
pH 7.5, 25°C
0.000013
N2-(2-chlorobenzyl)-N-hydroxy-N2-[(4-nitrophenyl)sulfanyl]-L-alaninamide
-
pH 7.5, 25°C
0.000011
N2-(2-chlorobenzyl)-N-hydroxy-N2-[(nonafluorobutyl)sulfonyl]-L-alaninamide
-
pH 7.5, 25°C
0.000071
N2-(2-chlorobenzyl)-N-hydroxy-N2-[(trichloromethyl)sulfonyl]-L-alaninamide
-
pH 7.5, 25°C
0.000006
N2-(2-chlorobenzyl)-N-hydroxy-N2-[[3-(trifluoromethyl)phenyl]sulfonyl]-L-alaninamide
-
pH 7.5, 25°C
0.000077
N2-(2-chlorobenzyl)-N2-(dimethylsulfamoyl)-N-hydroxy-L-alaninamide
-
pH 7.5, 25°C
0.000014
N2-(2-chlorobenzyl)-N2-[(2,4-difluorophenyl)carbamoyl]-N-hydroxy-L-alaninamide
-
pH 7.5, 25°C
0.000015
N2-(2-chlorobenzyl)-N2-[(2,5-dichlorophenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
pH 7.5, 25°C
0.000016
N2-(2-chlorobenzyl)-N2-[(2-nitrophenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
pH 7.5, 25°C
0.000015
N2-(2-chlorobenzyl)-N2-[(3,4-dichlorophenyl)carbamoyl]-N-hydroxy-L-alaninamide
-
pH 7.5, 25°C
0.000009
N2-(2-chlorobenzyl)-N2-[(3,5-dichloro-2-hydroxyphenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
pH 7.5, 25°C
0.00001
N2-(2-chlorobenzyl)-N2-[(3-chloro-4-nitrophenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
pH 7.5, 25°C
0.000017
N2-(2-chlorobenzyl)-N2-[(3-chlorophenyl)carbamoyl]-N-hydroxy-L-alaninamide
-
pH 7.5, 25°C
0.000011
N2-(2-chlorobenzyl)-N2-[(3-nitrophenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
pH 7.5, 25°C
0.000033
N2-(2-chlorobenzyl)-N2-[(4-bromophenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
pH 7.5, 25°C
0.000015
N2-(2-chlorobenzyl)-N2-[(4-chlorophenyl)carbamoyl]-N-hydroxy-L-alaninamide
-
pH 7.5, 25°C
0.000035
N2-(2-chlorobenzyl)-N2-[(4-chlorophenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
pH 7.5, 25°C
0.000018
N2-(2-chlorobenzyl)-N2-[(4-fluorophenyl)carbamoyl]-N-hydroxy-L-alaninamide
-
pH 7.5, 25°C
0.000036
N2-(2-chlorobenzyl)-N2-[(4-fluorophenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
pH 7.5, 25°C
0.00003
N2-(2-chlorobenzyl)-N2-[(4-iodophenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
pH 7.5, 25°C
0.000045
N2-(2-chlorobenzyl)-N2-[(4-methylphenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
pH 7.5, 25°C
0.000015
N2-(2-chlorobenzyl)-N2-[(4-nitrophenyl)sulfonyl]-N-hydroxy-L-alaninamide
-
pH 7.5, 25°C
0.000008
N2-(2-chlorobenzyl)-N2-[(heptadecafluorooctyl)sulfonyl]-N-hydroxy-L-alaninamide
-
pH 7.5, 25°C
0.000011
N2-(2-chlorobenzyl)-N2-[[(4-chlorophenyl)sulfonyl]carbamoyl]-N-hydroxy-L-alaninamide
-
pH 7.5, 25°C
0.000008 - 0.000009
N2-(2-chlorobenzyl)-N2-[[(4-fluorophenyl)sulfonyl]carbamoyl]-N-hydroxy-L-alaninamide
0.00001
N2-(2-chlorobenzyl)-N2-[[(4-methylphenyl)sulfonyl]carbamoyl]-N-hydroxy-L-alaninamide
-
pH 7.5, 25°C
0.00001
N2-(2-chlorobenzyl)-N2-[[5-(dimethylamino)naphthalen-1-yl]sulfonyl]-N-hydroxy-L-alaninamide
-
pH 7.5, 25°C
0.000054
N2-(benzylsulfonyl)-N2-(2-chlorobenzyl)-N-hydroxy-L-alaninamide
-
pH 7.5, 25°C
0.000092
N2-chlorobenzyl)-N-hydroxy-N2-(methylsulfonyl)-L-alaninamide
-
pH 7.5, 25°C
0.000011
N2-[[4-(acetylamino)phenyl]sulfonyl]-N2-(2-chlorobenzyl)-N-hydroxy-L-alaninamide
-
pH 7.5, 25°C
0.000005 - 0.34
p-O2NC6H4CH2CH2PO(OH)Gly-Pro-2-aminohexanoic acid
-
0.34
Pro6-Gly-Pro-Gly
-
pH 7.5, 25°C
-
0.000005
Pro6-Gly-Pro-Gly-H
-
pH 7.5, 25°C
-
0.02
Tannic acid
-
pH 7.5, 25°C
0.000008
tert-butyl (3-[(2-chlorobenzyl)[(1S)-2-(hydroxyamino)-1-methyl-2-oxoethyl]sulfamoyl]phenyl)carbamate
-
pH 7.5, 25°C
0.000009
tert-butyl (4-[(2-chlorobenzyl)[(1S)-2-(hydroxyamino)-1-methyl-2-oxoethyl]sulfamoyl]phenyl)carbamate
-
pH 7.5, 25°C
0.000008
tert-butyl (5-[(2-chlorobenzyl)[(1S)-2-(hydroxyamino)-1-methyl-2-oxoethyl]sulfamoyl]-2-methoxyphenyl)carbamate
-
pH 7.5, 25°C
0.000007
[3-[benzyl-(1-hydroxycarbamoyl-ethyl)-sulfamoyl]-phenyl]-carbamic acid tert-butyl ester
-
pH 7.5, 25°C
0.000009
[4-[benzyl-(1-hydroxycarbamoyl-ethyl)-sulfamoyl]-phenyl]-carbamic acid tert-butyl ester
-
pH 7.5, 25°C
0.000007
[5-[benzyl-(3-hydroxy-1-methyl-2-oxo-propyl)-sulfamoyl]-2-methoxy-phenyl]-carbamic acid tert-butyl ester
-
pH 7.5, 25°C
additional information
additional information
-
inhibition kinetics using diverse variants of 5-amino-2-mercapto-1,3,4-thiadiazoles, overview
-
IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.025 - 0.15
1,10-phenanthroline
0.035
cabozantinib
Hathewaya histolytica
-
IC50: 0.035 mM
-
0.415
erucic acid
Hathewaya histolytica
-
IC50: 0.415 mM
0.03
heptadecanoic acid
Hathewaya histolytica
-
IC50: 0.03 mM
0.375
linoleic acid
Hathewaya histolytica
-
IC50: 0.375 mM
0.46
linolenic acid
Hathewaya histolytica
-
IC50: 0.46 mM
0.27
myristic acid
Hathewaya histolytica
-
IC50: 0.27 mM
0.46
oleic acid
Hathewaya histolytica
-
IC50: 0.46 mM
0.405
palmitoleic acid
Hathewaya histolytica
-
IC50: 0.405 mM
0.125
pentadecanoic acid
Hathewaya histolytica
-
IC50: 0.125 mM
0.03
stearic acid
Hathewaya histolytica
-
IC50: 0.03 mM
0.5
additional information
Hathewaya histolytica
-
no inhibition by lauric acid, behenic acid, docosahexaenoic acid and eicosapentaenoic acid. IC50 above 0.5 mM: arachidic acid and gamma-linolenic acid
-
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
7.02
-
-
additional information
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
6.5 - 8.8
7.6
-
-
pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
4.2 - 10.2
-
pH 10.2: about 85% of activity maximum; pH 4.2: about 20% of activity maximum
5 - 11
-
pH 11: about 35% of activity maximum; pH 5: about 35% of activity maximum
5.5 - 8.5
-
pH 5.5: about 40% of activity maximum; pH 8.5: about 20% of activity maximum
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
35 - 40
-
-
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
additional information
-
intimately associated with the cell but released during autolysis
-
Manually annotated by BRENDA team
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
11470
-
mutant enzyme S906F in presence of 1 mM Ca2+, gel filtration
11750
-
mutant enzyme S906A in presence of 1 mM Ca2+, gel filtration
11810
-
mutant enzyme Q972A in presence of 1 mM Ca2+, gel filtration
11910
-
mutant enzyme V973A in presence of 1 mM Ca2+, gel filtration
11920
-
wild-type enzyme in presence of 1 mM Ca2+, gel filtration
13720
-
mutant enzyme E901A in presence of 1 mM Ca2+, gel filtration
13750
-
mutant enzyme D904A in presence of 1 mM Ca2+, gel filtration
14390
-
mutant enzyme E899A in presence of 1 mM Ca2+, gel filtration
15370
-
mutant enzyme D930A in presence of 1 mM Ca2+, gel filtration
15420
-
mutant enzyme D930A in presence of 1 mM EDTA, gel filtration
15730
-
mutant enzyme N903A in presence of 1 mM Ca2+, gel filtration
15790
-
mutant enzyme D927A in presence of 1 mM Ca2+, gel filtration
15890
-
mutant enzyme E899A in presence of 1 mM EDTA, gel filtration
16160
-
mutant enzyme D904A in presence of 1 mM EDTA, gel filtration
16190
-
mutant enzyme D927A in presence of 1 mM EDTA, gel filtration
16410
-
mutant enzyme S906A in presence of 1 mM EDTA, gel filtration
16430
-
wild-type enzyme in presence of 1 mM EGTA, gel filtration
16470
-
mutant enzyme Q972A in presence of 1 mM EDTA, gel filtration
16510
-
mutant enzyme V973A in presence of 1 mM EDTA, gel filtration
16530
-
mutant enzyme N903A in presence of 1 mM EDTA, gel filtration
16650
-
mutant enzyme S906F in presence of 1 mM EDTA, gel filtration
24000
-
x * 24000 + x * 28000, SDS-PAGE after denaturation with SDS and beta-mercaptoethanol
28000
-
x * 24000 + x * 28000, SDS-PAGE after denaturation with SDS and beta-mercaptoethanol
35000
-
x * 35000, SDS-PAGE
62000
-
gel filtration
64000
-
1 * 64000, SDS-PAGE
68000
-
? * 68000, alpha, SDS-PAGE
70000
-
gel filtration
72000
-
1 * 72000, IIIb, SDS-PAGE
74000
-
gel filtration
75000
-
1 * 75000, no dissociation into subunits after lithium chloride treatment, SDS-PAGE; ? * 75000, SDS-PAGE
76000
-
? * 76000, C3, SDS-PAGE