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Literature summary for 3.4.24.3 extracted from

  • Shi, L.; Ermis, R.; Garcia, A.; Telgenhoff, D.; Aust, D.
    Degradation of human collagen isoforms by Clostridium collagenase and the effects of degradation products on cell migration (2010), Int. Wound J., 7, 87-95.
    View publication on PubMed

Application

Application Comment Organism
medicine Clostridium histolyticum collagenase can effectively digest collagen isoforms that are present in necrotic wound tissues. Collagenase treatment enhances cell migration mediated by collagenase itself and by collagen degradation products Hathewaya histolytica

Organism

Organism UniProt Comment Textmining
Hathewaya histolytica
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Collagen type I + H2O
-
Hathewaya histolytica ? Clostridium collagenase itself and the degradation products of type I and III collagens lead toan increase in keratinocyte and fibroblast migration ?
Collagen type III + H2O
-
Hathewaya histolytica ? Clostridium collagenase itself and the degradation products of type I and III collagens lead toan increase in keratinocyte and fibroblast migration ?
collagen type IV + H2O
-
Hathewaya histolytica ? degradation products of collagen type IV induce fibroblast migration ?
collagen type V + H2O
-
Hathewaya histolytica ?
-
?
additional information no substrate: collagen type VI Hathewaya histolytica ?
-
?