Application | Comment | Organism |
---|---|---|
medicine | Clostridium histolyticum collagenase can effectively digest collagen isoforms that are present in necrotic wound tissues. Collagenase treatment enhances cell migration mediated by collagenase itself and by collagen degradation products | Hathewaya histolytica |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Hathewaya histolytica | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Collagen type I + H2O | - |
Hathewaya histolytica | ? | Clostridium collagenase itself and the degradation products of type I and III collagens lead toan increase in keratinocyte and fibroblast migration | ? | |
Collagen type III + H2O | - |
Hathewaya histolytica | ? | Clostridium collagenase itself and the degradation products of type I and III collagens lead toan increase in keratinocyte and fibroblast migration | ? | |
collagen type IV + H2O | - |
Hathewaya histolytica | ? | degradation products of collagen type IV induce fibroblast migration | ? | |
collagen type V + H2O | - |
Hathewaya histolytica | ? | - |
? | |
additional information | no substrate: collagen type VI | Hathewaya histolytica | ? | - |
? |