Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.24.3 extracted from

  • Krishnamoorthy, G.; Sehgal, P.K.; Mandal, A.B.; Sadulla, S.
    Studies on collagen-tannic acid-collagenase ternary system: Inhibition of collagenase against collagenolytic degradation of extracellular matrix component of collagen (2011), J. Enzyme Inhib. Med. Chem., 27, 451-457.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Tannic acid competitive, almost complete inhibition. Pretreatment of collagen fibers with tannic acid results in polymerization and complex formation Hathewaya histolytica

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.555
-
N-[3-(2-furyl) acryloyl]-L-Leu-Gly-L-Pro-L-Ala pH 7.5, 25°C Hathewaya histolytica

Localization

Localization Comment Organism GeneOntology No. Textmining

Organism

Organism UniProt Comment Textmining
Hathewaya histolytica
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-[3-(2-furyl) acryloyl]-L-Leu-Gly-L-Pro-L-Ala + H2O
-
Hathewaya histolytica ?
-
?

Synonyms

Synonyms Comment Organism
ChC
-
Hathewaya histolytica

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.02
-
Tannic acid pH 7.5, 25°C Hathewaya histolytica