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Literature summary for 3.4.24.3 extracted from

  • Bond, M.D.; van Wart, H.E.
    Characterization of the individual collagenases from Clostridium histolyticum (1984), Biochemistry, 23, 3085-3091.
    View publication on PubMed
Search for more literature for 3.4.24.3

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information
-
 Hathewaya histolytica

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ Ca-enzyme, alpha: 2.2, beta: 7.9, gamma: 3.1, delta: 3.0, epsilon: 4. 5, zeta: 6.5 mol Ca2+ per mol enzyme Hathewaya histolytica
Zn2+ 1 mol zinc per mol enzyme Hathewaya histolytica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Collagen + H2O Hathewaya histolytica degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence Pro-Xaa-Gly-Pro ?
-
 ?

Organism

Organism UniProt Comment Textmining
Hathewaya histolytica
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Collagen + H2O degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence-Pro-Xaa-Gly-Pro, nondenatured triple helical form Hathewaya histolytica Hydrolyzed collagen
-
 ?
Collagen + H2O degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence Pro-Xaa-Gly-Pro Hathewaya histolytica ?
-
 ?