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Literature summary for 3.4.24.3 extracted from

  • Dokumcu, Z.; Ergun, O.; Celik, H.A.; Aydemir, S.; Sezak, M.; Ozok, G.; Celik, A.
    Clostridial collagenase aggravates the systemic inflammatory response in rats with partial-thickness burns (2008), Burns, 34, 935-941.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Collagen + H2O Clostridium sp. clostridial collagenase A is effective in degrading collagen in eschar tissue and promoting healing in partial-thickness burns, CCA aggravates the systemic inflammatory response in rats with partial-thickness burns, inflammatory reactions such as fever, leukocytosis or leukocytopenia and increased CRP levels in sera are often observed in a significant proportion of burn victims treated with CCA ointment, although synchronous wound swab cultures show no signs of infection, overview ?
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Organism

Organism UniProt Comment Textmining
Clostridium sp.
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-
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Collagen + H2O proteolytic degradation Clostridium sp. ?
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?
Collagen + H2O clostridial collagenase A is effective in degrading collagen in eschar tissue and promoting healing in partial-thickness burns, CCA aggravates the systemic inflammatory response in rats with partial-thickness burns, inflammatory reactions such as fever, leukocytosis or leukocytopenia and increased CRP levels in sera are often observed in a significant proportion of burn victims treated with CCA ointment, although synchronous wound swab cultures show no signs of infection, overview Clostridium sp. ?
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?

Synonyms

Synonyms Comment Organism
CCA
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Clostridium sp.
clostridial collagenase A
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Clostridium sp.