6.3.4.4: adenylosuccinate synthase

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For detailed information about adenylosuccinate synthase, go to the full flat file.

Reaction

Synonyms

adenosylsuccinate synthase, adenosylsuccinate synthetase, adenylo-succinate synthetase, Adenylosuccinate synthase, Adenylosuccinate synthetase, adenylosuccinate synthetase 1, AdSS, AdSS1, AdSS2, AdSSL1, AMPSase, AMPsS, Arabdss, AS-synthetase, ASS, IMP--aspartate ligase, IMP-aspartate ligase, mouse muscle synthetase, PfAdSS, purA, Succino-AMP synthetase, Succinoadenylic kinosynthetase, Wheatadss

ECTree

     6 Ligases

         6.3 Forming carbon-nitrogen bonds

             6.3.4 Other carbon-nitrogen ligases

                6.3.4.4 adenylosuccinate synthase

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Results	in table
4	Activating Compound
48857	AA Sequence
8	Application
1	CAS Registry Number
35	Cloned(Commentary)
4	Cofactor
26	Crystallization (Commentary)
149	Disease/ Diagnostics
4	General Information
5	General Stability
228	Inhibitors
4	kcat/KM [mM/s]
69	Ki Value [mM]
326	KM Value [mM]
2	Localization
45	Metals/Ions
44	Molecular Weight [Da]
58	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
416	Organism
6	Pathway
75	PDB ID
18	pH Optimum
5	pH Range
1	pH Stability
5	pI Value
63	Protein Variants
35	Purification (Commentary)
9	Reaction
1	Reaction Type
135	Reference
50	Source Tissue
13	Specific Activity [micromol/min/mg]
5	Storage Stability
197	Substrates and Products (Substrate)
32	Subunits
127	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Stability [°C]
76	Turnover Number [1/s]

Storage Stability

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Storage Stability on EC 6.3.4.4 - adenylosuccinate synthase

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STORAGE STABILITY

ORGANISM

UNIPROT

LITERATURE

-20°C, or 0°C, rapid loss of enzyme activity in dilute solution

Rattus norvegicus

-

1539

-20°C, remains stable for months

Saccharomyces cerevisiae

-

649670

-20°C, stable without any decrease in activity for at least 6 months

Methanocaldococcus jannaschii

Q57981

726945

-70°C, stable for more than 2 years

Dictyostelium discoideum

-

1552

4°C, glycerol and EDTA stabilizes enzyme activity during storage, stable for at least 3 weeks

Plasmodium falciparum

-

653751