6.3.4.4: adenylosuccinate synthase

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Synonyms

adenosylsuccinate synthase, adenosylsuccinate synthetase, adenylo-succinate synthetase, Adenylosuccinate synthase, Adenylosuccinate synthetase, adenylosuccinate synthetase 1, AdSS, AdSS1, AdSS2, AdSSL1, AMPSase, AMPsS, Arabdss, AS-synthetase, ASS, IMP--aspartate ligase, IMP-aspartate ligase, mouse muscle synthetase, PfAdSS, purA, Succino-AMP synthetase, Succinoadenylic kinosynthetase, Wheatadss

ECTree

     6 Ligases

         6.3 Forming carbon-nitrogen bonds

             6.3.4 Other carbon-nitrogen ligases

                6.3.4.4 adenylosuccinate synthase

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4	Activating Compound
48857	AA Sequence
8	Application
1	CAS Registry Number
35	Cloned(Commentary)
4	Cofactor
26	Crystallization (Commentary)
149	Disease/ Diagnostics
4	General Information
5	General Stability
228	Inhibitors
4	kcat/KM [mM/s]
69	Ki Value [mM]
326	KM Value [mM]
2	Localization
45	Metals/Ions
44	Molecular Weight [Da]
58	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
416	Organism
6	Pathway
75	PDB ID
18	pH Optimum
5	pH Range
1	pH Stability
5	pI Value
63	Protein Variants
35	Purification (Commentary)
9	Reaction
1	Reaction Type
135	Reference
50	Source Tissue
13	Specific Activity [micromol/min/mg]
5	Storage Stability
197	Substrates and Products (Substrate)
32	Subunits
127	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Stability [°C]
76	Turnover Number [1/s]

Temperature Stability

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Temperature Stability on EC 6.3.4.4 - adenylosuccinate synthase

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TEMPERATURE STABILITY

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

65 - 90

Methanocaldococcus jannaschii

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thermal unfolding of AdSS exhibits a melting temperature of 85°C with the process being only partially reversible, the half life of inactivation is 340 min, 150 min, 110 min, 60 min, 30 min and 15 min at 65, 70, 75, 80, 85 and 90°C, respectively

691098