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Disease on EC 6.3.4.4 - adenylosuccinate synthase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Acidosis
Effect of acidosis and uninephrectomy on isozymes of adenylosuccinate synthetase in rat kidney.
Adenocarcinoma of Lung
Adenylosuccinate synthetase 1 gene is a novel target of deletion in lung adenocarcinoma.
adenylosuccinate lyase deficiency
Adenylosuccinate Synthetase and Adenylosuccinate Lyase Deficiencies Trigger Growth and Infectivity Deficits in Leishmania donovani.
Ataxia Telangiectasia
Association analyses of the interaction between the ADSS and ATM genes with schizophrenia in a Chinese population.
Carcinogenesis
Adenylosuccinate synthetase 1 gene is a novel target of deletion in lung adenocarcinoma.
Carcinoma
Regulation of purine metabolism: a comparative study of the kinetic properties of adenylosuccinate synthetases from various sources.
Carcinoma 256, Walker
Regulation of purine metabolism: a comparative study of the kinetic properties of adenylosuccinate synthetases from various sources.
Carcinoma, Hepatocellular
Enzymes of purine metabolism in cancer.
Cardiomegaly
The adenylosuccinate synthetase-1 gene is activated in the hypertrophied heart.
Distal Myopathies
ADSSL1 mutation relevant to autosomal recessive adolescent onset distal myopathy.
Comparative transcriptome analysis of skeletal muscle in ADSSL1 myopathy.
Distal myopathy with ADSSL1 mutations in Korean patients.
Expanding the disease phenotype of ADSSL1-associated myopathy in non-Korean patients.
Gout
Purine oversecretion in cultured murine lymphoma cells deficient in adenylosuccinate synthetase: genetic model for inherited hyperuricemia and gout.
Infections
Genome-wide identification of Streptococcus pneumoniae genes essential for bacterial replication during experimental meningitis.
Insulinoma
Adenylosuccinate Is an Insulin Secretagogue Derived from Glucose-Induced Purine Metabolism.
Leukemia
Identification of the antimetabolite of L-alanosine, L-alanosyl-5-amino-4-imidazolecarboxylic acid ribonucleotide, in tumors and assessment of its inhibition of adenylosuccinate synthetase.
Molecular cloning and characterization of a novel muscle adenylosuccinate synthetase, AdSSL1, from human bone marrow stromal cells.
Leukemia, Experimental
Synthesis and in vitro biological evaluation of N-[(5-amino-1-beta-D-ribofuranosyl-1H-imidazol-4-yl)carbonyl]-3- (hydroxynitrosamino)-L-alanine (L-alanosine AICO ribonucleoside).
Lung Neoplasms
Adenylosuccinate synthetase 1 gene is a novel target of deletion in lung adenocarcinoma.
Lymphoma
Purine oversecretion in cultured murine lymphoma cells deficient in adenylosuccinate synthetase: genetic model for inherited hyperuricemia and gout.
Lymphoma, T-Cell
Abnormal regulation of de novo purine synthesis and purine salvage in a cultured mouse T-cell lymphoma mutant partially deficient in adenylosuccinate synthetase.
Abnormal regulation of purine metabolism in a cultured mouse T-cell lymphoma mutant partially deficient in adenylosuccinate synthetase.
Malaria
Crystal structure of fully ligated adenylosuccinate synthetase from Plasmodium falciparum.
Enrichment of reticulocytes from whole blood using aqueous multiphase systems of polymers.
Meningitis, Pneumococcal
Genome-wide identification of Streptococcus pneumoniae genes essential for bacterial replication during experimental meningitis.
Muscle Cramp
Enzymes of the purine nucleotide cycle in muscle of patients with exercise intolerance.
Muscle Weakness
Distal myopathy with ADSSL1 mutations in Korean patients.
Expanding the disease phenotype of ADSSL1-associated myopathy in non-Korean patients.
Muscular Diseases
ADSSL1 mutation relevant to autosomal recessive adolescent onset distal myopathy.
ADSSL1 myopathy is the most common nemaline myopathy in Japan with variable clinical features.
Anti-apoptotic Effects of Human Wharton's Jelly-derived Mesenchymal Stem Cells on Skeletal Muscle Cells Mediated via Secretion of XCL1.
Comparative transcriptome analysis of skeletal muscle in ADSSL1 myopathy.
Distal myopathy with ADSSL1 mutations in Korean patients.
Electron Microscopy Pathology of ADSSL1 Myopathy.
Enzymes of the purine nucleotide cycle in muscle of patients with exercise intolerance.
Muscular Dystrophy, Duchenne
Identifying and circumventing the defect in Duchenne muscular dystrophy: clinical and biochemical restoration after practical intervention.
Myopathies, Nemaline
ADSSL1 myopathy is the most common nemaline myopathy in Japan with variable clinical features.
Neoplasms
Adenylosuccinate synthetase 1 gene is a novel target of deletion in lung adenocarcinoma.
Design, Synthesis and Evaluation of AdSS Bisubstrate Inhibitors.
Identification of differentially expressed proteins in spontaneous thymic lymphomas from knockout mice with deletion of p53.
Identification of the antimetabolite of L-alanosine, L-alanosyl-5-amino-4-imidazolecarboxylic acid ribonucleotide, in tumors and assessment of its inhibition of adenylosuccinate synthetase.
Isozyme shift of adenylosuccinate synthase in rat and human neoplasms.
Molecular transformation of tumor adenylosuccinate synthetase and characteristics of its converting factor.
Oxidation of glutamine in cancer cells and regeneration of adenylates via adenylosuccinate synthetase.
Purification and properties of adenylosuccinate synthetase from Yoshida sarcoma ascites tumor cells.
Regulation of purine metabolism. Adenylosuccinate synthetase from Novikoff ascites tumor cells.
Regulation of purine metabolism: a comparative study of the kinetic properties of adenylosuccinate synthetases from various sources.
Synthesis and in vitro biological evaluation of N-[(5-amino-1-beta-D-ribofuranosyl-1H-imidazol-4-yl)carbonyl]-3- (hydroxynitrosamino)-L-alanine (L-alanosine AICO ribonucleoside).
Sarcoma, Yoshida
Molecular transformation of tumor adenylosuccinate synthetase and characteristics of its converting factor.
Purification and properties of adenylosuccinate synthetase from Yoshida sarcoma ascites tumor cells.