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6.3.4.4: adenylosuccinate synthase

This is an abbreviated version!
For detailed information about adenylosuccinate synthase, go to the full flat file.

Word Map on EC 6.3.4.4

Reaction

GTP
+
IMP
+
L-aspartate
=
GDP
+
phosphate
+
N6-(1,2-dicarboxyethyl)-AMP

Synonyms

adenosylsuccinate synthase, adenosylsuccinate synthetase, adenylo-succinate synthetase, Adenylosuccinate synthase, Adenylosuccinate synthetase, adenylosuccinate synthetase 1, AdSS, AdSS1, AdSS2, AdSSL1, AMPSase, AMPsS, Arabdss, AS-synthetase, ASS, IMP--aspartate ligase, IMP-aspartate ligase, mouse muscle synthetase, PfAdSS, purA, Succino-AMP synthetase, Succinoadenylic kinosynthetase, Wheatadss

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.4 Other carbon-nitrogen ligases
                6.3.4.4 adenylosuccinate synthase

KI Value

KI Value on EC 6.3.4.4 - adenylosuccinate synthase

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0406
6-(4-bromo-2,3-dioxobutyl)thioadenosine 5'-monophosphate
-
pH 7.0, 25°C
0.0094 - 2.7
adenylosuccinate
0.0582 - 6
AMP
4
ATP
-
pH 8.0, 25°C
8
Cl-
-
pH 8.0, 25°C
1.5 - 4.8
D-fructose 1,6 bisphosphate
0.016 - 0.67
D-fructose 1,6-bisphosphate
0.04 - 0.64
fumarate
0.005 - 0.0822
GDP
0.012 - 0.12
GMP
0.00032 - 0.017
Hadacidin
0.078 - 3.1
Maleate
0.0105 - 0.0269
N-formyl-N-hydroxyglycine
1.9 - 28
phosphate
0.0061 - 0.05
ppGpp
0.08 - 1
succinate