6.2.1.30: phenylacetate-CoA ligase

This is an abbreviated version!
For detailed information about phenylacetate-CoA ligase, go to the full flat file.

Word Map on EC 6.2.1.30

6.2.1.30

phenylacetic

penicillin

chrysogenum

putida

ligases

isopenicillin

cenocepacia

phenylglyoxylate

benzoyl-coa

denitrifying

synthesis

3-hydroxyphenylacetic

phenylacetaldehyde

analysis

Reaction

Synonyms

EC 6.2.1.21, More, PA-CoA ligase, PAA-CoA ligase, PaaF2, PaaK1, PaaK2, PCL, phenyl/phenoxyacetic acid activating enzyme, phenyl/phenoxyacetyl-CoA-ligase, phenylacetyl CoA ligase, phenylacetyl-CoA ligase, phenylacetyl-CoA ligase (AMP-forming), phenylacetyl-coenzyme A ligase, Phl protein, phlB, PhlC, styrene-specific PA-CoA ligase, synthetase, phenacyl coenzyme A

ECTree

6 Ligases

6.2 Forming carbon-sulfur bonds

6.2.1 Acid-thiol ligases

6.2.1.30 phenylacetate-CoA ligase

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Results	in table
4	Activating Compound
13416	AA Sequence
3	Application
1	CAS Registry Number
14	Cloned(Commentary)
6	Cofactor
2	Crystallization (Commentary)
8	Expression
27	General Information
7	General Stability
30	Inhibitors
7	kcat/KM [mM/s]
1	Ki Value [mM]
41	KM Value [mM]
13	Localization
17	Metals/Ions
12	Molecular Weight [Da]
32	Natural Substrates/ Products (Substrates)
108	Organism
1	Oxidation Stability
11	Pathway
6	PDB ID
8	pH Optimum
3	pH Range
4	pI Value
12	Protein Variants
10	Purification (Commentary)
1	Reaction
2	Reaction Type
50	Reference
16	Source Tissue
15	Specific Activity [micromol/min/mg]
8	Storage Stability
113	Substrates and Products (Substrate)
13	Subunits
32	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
2	Temperature Range [°C]
6	Temperature Stability [°C]
29	Turnover Number [1/s]

KM Value

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KM Value on EC 6.2.1.30 - phenylacetate-CoA ligase

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0.23 - 1.5

3-Chlorophenylacetate

2 entries

0.17 - 0.87

3-hydroxyphenylacetate

2 entries

0.54

4-hydroxyphenylacetate

Burkholderia cenocepacia

B4E7B5, B4EL89

pH and temperature not specified in the publication

727874

0.006 - 9.7

ATP

6 entries

24.4

Butyric acid

Penicillium chrysogenum

O74725

pH 8.5, 30°C, recombinant enzyme

690837

0.07

caprate

Penicillium chrysogenum

D3GE78

recombinant enzyme, pH 7.5, 30°C

727565

0.026

caproate

Penicillium chrysogenum

D3GE78

recombinant enzyme, pH 7.5, 30°C

727565

0.046

caprylate

Penicillium chrysogenum

D3GE78

recombinant enzyme, pH 7.5, 30°C

727565

0.03 - 1

CoA

6 entries

0.001

myristic acid

Penicillium chrysogenum

O74725

below, pH 8.5, 30°C, recombinant enzyme

690837

0.092

palmitate

Penicillium chrysogenum

D3GE78

recombinant enzyme, pH 7.5, 30°C

727565

0.257 - 2.1

Phenoxyacetate

2 entries

0.0029 - 16.5

phenylacetate

9 entries

propionic acid

Penicillium chrysogenum

O74725

pH 8.5, 30°C, recombinant enzyme

690837

0.841

stearate

Penicillium chrysogenum

D3GE78

recombinant enzyme, pH 7.5, 30°C

727565

0.19

trans-cinnamic acid

Penicillium chrysogenum

O74725

pH 8.5, 30°C, recombinant enzyme

690837

additional information

7 entries