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6.2.1.30: phenylacetate-CoA ligase

This is an abbreviated version!
For detailed information about phenylacetate-CoA ligase, go to the full flat file.

Word Map on EC 6.2.1.30

Reaction

ATP
+
phenylacetate
 +
CoA
=
AMP
 +
diphosphate
 +
phenylacetyl-CoA

Synonyms

EC 6.2.1.21, More, PA-CoA ligase, PAA-CoA ligase, PaaF2, PaaK1, PaaK2, PCL, phenyl/phenoxyacetic acid activating enzyme, phenyl/phenoxyacetyl-CoA-ligase, phenylacetyl CoA ligase, phenylacetyl-CoA ligase, phenylacetyl-CoA ligase (AMP-forming), phenylacetyl-coenzyme A ligase, Phl protein, phlB, PhlC, styrene-specific PA-CoA ligase, synthetase, phenacyl coenzyme A

ECTree

     6 Ligases
         6.2 Forming carbon-sulfur bonds
             6.2.1 Acid-thiol ligases
                6.2.1.30 phenylacetate-CoA ligase

Turnover Number

Turnover Number on EC 6.2.1.30 - phenylacetate-CoA ligase

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1.6 - 1.67
3-Chlorophenylacetate
1.83 - 2.67
3-hydroxyphenylacetate
1.17
4-hydroxyphenylacetate
pH and temperature not specified in the publication
1.7 - 42.9
ATP
9.7
Butyric acid
pH 8.5, 30°C, recombinant enzyme
0.102
caprate
recombinant enzyme, pH 7.5, 30°C
0.076
caproate
recombinant enzyme, pH 7.5, 30°C
0.073
caprylate
recombinant enzyme, pH 7.5, 30°C
1.5 - 60.5
CoA
0.026
palmitate
recombinant enzyme, pH 7.5, 30°C
0.063 - 12
Phenoxyacetate
0.099 - 40
phenylacetate
0.062
stearate
recombinant enzyme, pH 7.5, 30°C
41.2
trans-cinnamic acid
pH 8.5, 30°C, recombinant enzyme