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6.2.1.30: phenylacetate-CoA ligase

This is an abbreviated version!
For detailed information about phenylacetate-CoA ligase, go to the full flat file.

Word Map on EC 6.2.1.30

Reaction

ATP
+
phenylacetate
+
CoA
=
AMP
+
diphosphate
+
phenylacetyl-CoA

Synonyms

EC 6.2.1.21, More, PA-CoA ligase, PAA-CoA ligase, PaaF2, PaaK1, PaaK2, PCL, phenyl/phenoxyacetic acid activating enzyme, phenyl/phenoxyacetyl-CoA-ligase, phenylacetyl CoA ligase, phenylacetyl-CoA ligase, phenylacetyl-CoA ligase (AMP-forming), phenylacetyl-coenzyme A ligase, Phl protein, phlB, PhlC, styrene-specific PA-CoA ligase, synthetase, phenacyl coenzyme A

ECTree

     6 Ligases
         6.2 Forming carbon-sulfur bonds
             6.2.1 Acid-thiol ligases
                6.2.1.30 phenylacetate-CoA ligase

Reference

Reference on EC 6.2.1.30 - phenylacetate-CoA ligase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Schneider, S.; Mohamed, M.E.S.; Fuchs, G.
Anaerobic metabolism of L-phenylalanine via benzoyl-CoA in the denitrifying bacterium Thauera aromatica
Arch. Microbiol.
168
310-320
1997
Thauera aromatica
Manually annotated by BRENDA team
Martinez-Blanco, H.; Reglero, A.; Rodriguez-Aparicio, L.B.; Luengo, J.M.
Purification and biochemical characterization of phenylacetyl-CoA ligase from Pseudomonas putida
J. Biol. Chem.
265
7084-7090
1990
Pseudomonas putida
Manually annotated by BRENDA team
Rodriguez-Aparacio, L.B.; Reglero, A.; Martinez-Blanco, H.; Luengo, J.M.
Fluorometric determination of phenylacetyl-CoA ligase from Pseudomonas putida: a very sensitive assay for a newly described enzyme
Biochim. Biophys. Acta
1073
431-433
1991
Pseudomonas putida
Manually annotated by BRENDA team
El-Said Mohamed, M.; Fuchs, G.
Purification and characterization of phenylacetyl-coenzyme A ligase from a denitrifying Pseudomonas sp., an enzyme involved in the anaerobic degradation of phenylacetate
Arch. Microbiol.
159
544-562 (c)
1993
Pseudomonas sp., Pseudomonas sp. KB 740
Manually annotated by BRENDA team
Kogekar, R.G.; Desphpande, V.N.
Biosynthesis of Penicillin in vitro: purification & properties of phenyl/phenoxyacetic acid activating enzyme
Indian J. Biochem. Biophys.
19
257-261
1982
Penicillium chrysogenum
Manually annotated by BRENDA team
Vitovski, S.
Phenylacetate-coenzyme A ligase is induced during growth on phenylacetic acid in different bacteria of several genera
FEMS Microbiol. Lett.
108
1-5
1993
Achromobacter denitrificans, Acinetobacter calcoaceticus, Acinetobacter calcoaceticus EGB, Burkholderia cepacia, Burkholderia cepacia 104P, Burkholderia cepacia 132P, Burkholderia cepacia 91P, Escherichia coli, Escherichia coli ATCC 11105, Providencia rettgeri, Providencia rettgeri ATCC 31052, Pseudomonas fluorescens, Pseudomonas putida, Pseudomonas putida 63P, Pseudomonas sp., Pseudomonas sp. MT14
Manually annotated by BRENDA team
Mohamed Mel, S.; Ismail, W.; Heider, J.; Fuchs, G.
Aerobic metabolism of phenylacetic acids in Azoarcus evansii
Arch. Microbiol.
178
180-192
2002
Aromatoleum evansii
Manually annotated by BRENDA team
Minambres, B.; Martinez-Blanco, H.; Olivera, E.R.; Garcia, B.; Diez, B.; Barredo, J.L.; Moreno, M.A.; Schleissner, C.; Salto, F.; Luengo, J.M.
Molecular cloning and expression in different microbes of the DNA encoding Pseudomonas putida U phenylacetyl-CoA ligase. Use of this gene to improve the rate of benzylpenicillin biosynthesis in Penicillium chrysogenum
J. Biol. Chem.
271
33531-33538
1996
Pseudomonas putida
Manually annotated by BRENDA team
Mohamed, M.E.S.
Biochemical and molecular characterization of phenylacetate-coenzyme A ligase, an enzyme catalyzing the first step in aerobic metabolism of phenylacetic acid in Azoarcus evansii
J. Bacteriol.
182
286-294
2000
Aromatoleum evansii
Manually annotated by BRENDA team
Lamas-Maceiras, M.; Vaca, I.; Rodriguez, E.; Casqueiro, J.; Martin, J.F.
Amplification and disruption of the phenylacetyl-CoA ligase gene of Penicillium chrysogenum encoding an aryl-capping enzyme that supplies phenylacetic acid to the isopenicillin N acyltransferase
Biochem. J.
395
147-155
2005
Penicillium chrysogenum, Penicillium chrysogenum AS-P-78
Manually annotated by BRENDA team
Ward, P.G.; KE, O.C.
Induction and quantification of phenylacyl-CoA ligase enzyme activities in Pseudomonas putida CA-3 grown on aromatic carboxylic acids
FEMS Microbiol. Lett.
251
227-232
2005
Pseudomonas putida, Pseudomonas putida CA-3
Manually annotated by BRENDA team
Di Gennaro, P.; Ferrara, S.; Ronco, I.; Galli, E.; Sello, G.; Papacchini, M.; Bestetti, G.
Styrene lower catabolic pathway in Pseudomonas fluorescens ST: identification and characterization of genes for phenylacetic acid degradation
Arch. Microbiol.
188
117-125
2007
Pseudomonas fluorescens, Pseudomonas fluorescens ST
Manually annotated by BRENDA team
Wang, F.Q.; Liu, J.; Dai, M.; Ren, Z.H.; Su, C.Y.; He, J.G.
Molecular cloning and functional identification of a novel phenylacetyl-CoA ligase gene from Penicillium chrysogenum
Biochem. Biophys. Res. Commun.
360
453-458
2007
Penicillium chrysogenum (A7KUK6), Penicillium chrysogenum
Manually annotated by BRENDA team
Koetsier, M.J.; Jekel, P.A.; van den Berg, M.A.; Bovenberg, R.A.; Janssen, D.B.
Characterization of a phenylacetate-CoA ligase from Penicillium chrysogenum
Biochem. J.
417
467-476
2008
Penicillium chrysogenum (O74725), Penicillium chrysogenum
Manually annotated by BRENDA team
Erb, T.J.; Ismail, W.; Fuchs, G.
Phenylacetate metabolism in thermophiles: characterization of phenylacetate-CoA ligase, the initial enzyme of the hybrid pathway in Thermus thermophilus
Curr. Microbiol.
57
27-32
2008
Thermus thermophilus (Q72K16), Thermus thermophilus, Thermus thermophilus HB27 / ATCC BAA-163 / DSM 7039 (Q72K16)
Manually annotated by BRENDA team
del Peso-Santos, T.; Shingler, V.; Perera, J.
The styrene-responsive StyS/StyR regulation system controls expression of an auxiliary phenylacetyl-coenzyme A ligase: implications for rapid metabolic coupling of the styrene upper- and lower-degradative pathways
Mol. Microbiol.
69
317-330
2008
Pseudomonas sp., Pseudomonas sp. Y2
Manually annotated by BRENDA team
Kiel, J.A.; van den Berg, M.A.; Fusetti, F.; Poolman, B.; Bovenberg, R.A.; Veenhuis, M.; van der Klei, I.J.
Matching the proteome to the genome: the microbody of penicillin-producing Penicillium chrysogenum cells
Funct. Integr. Genomics
9
167-184
2009
Penicillium chrysogenum
Manually annotated by BRENDA team
Kim, J.; Yeom, J.; Jeon, C.O.; Park, W.
Intracellular 2-keto-3-deoxy-6-phosphogluconate is the signal for carbon catabolite repression of phenylacetic acid metabolism in Pseudomonas putida KT2440
Microbiology
155
2420-2428
2009
Pseudomonas putida, Pseudomonas putida KT 2240
Manually annotated by BRENDA team
Gidijala, L.; Kiel, J.A.; Douma, R.D.; Seifar, R.M.; van Gulik, W.M.; Bovenberg, R.A.; Veenhuis, M.; van der Klei, I.J.
An engineered yeast efficiently secreting penicillin
PLoS ONE
4
e8317
2009
Penicillium chrysogenum
Manually annotated by BRENDA team
Meijer, W.H.; Gidijala, L.; Fekken, S.; Kiel, J.A.; van den Berg, M.A.; Lascaris, R.; Bovenberg, R.A.; van der Klei, I.J.
Peroxisomes are required for efficient penicillin biosynthesis in Penicillium chrysogenum
Appl. Environ. Microbiol.
76
5702-5709
2010
Penicillium chrysogenum, Penicillium chrysogenum NRRL1951
Manually annotated by BRENDA team
Martin, J.F.; Ullan, R.V.; Garcia-Estrada, C.
Regulation and compartmentalization of beta-lactam biosynthesis
Microb. Biotechnol.
3
285-299
2010
Penicillium sp.
Manually annotated by BRENDA team
Yu, Z.L.; Liu, J.; Wang, F.Q.; Dai, M.; Zhao, B.H.; He, J.G.; Zhang, H.
Cloning and characterization of a novel CoA-ligase gene from Penicillium chrysogenum
Folia Microbiol. (Praha)
56
246-252
2011
Penicillium chrysogenum (D3GE78), Penicillium chrysogenum WIS 54-1255 (D3GE78)
Manually annotated by BRENDA team
Imolorhe, I.A.; Cardona, S.T.
3-Hydroxyphenylacetic acid induces the Burkholderia cenocepacia phenylacetic acid degradation pathway - toward understanding the contribution of aromatic catabolism to pathogenesis
Front. Cell. Infect. Microbiol.
1
14
2011
Burkholderia cenocepacia (B4E7B5), Burkholderia cenocepacia (B4EL89), Burkholderia cenocepacia, Burkholderia cenocepacia DSM 16553 (B4E7B5), Burkholderia cenocepacia DSM 16553 (B4EL89)
Manually annotated by BRENDA team
Law, A.; Boulanger, M.J.
Defining a structural and kinetic rationale for paralogous copies of phenylacetate-CoA ligases from the cystic fibrosis pathogen Burkholderia cenocepacia J2315
J. Biol. Chem.
286
15577-15585
2011
Burkholderia cenocepacia (B4E7B5), Burkholderia cenocepacia (B4EL89), Burkholderia cenocepacia, Burkholderia cenocepacia DSM 16553 (B4E7B5), Burkholderia cenocepacia DSM 16553 (B4EL89)
Manually annotated by BRENDA team