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4.2.2.7: heparin lyase

This is an abbreviated version!
For detailed information about heparin lyase, go to the full flat file.

Word Map on EC 4.2.2.7

Reaction

Eliminative cleavage of polysaccharides containing (1->4)-linked D-glucuronate or L-iduronate residues and (1->4)-alpha-linked 2-sulfoamino-2-deoxy-6-sulfo-D-glucose residues to give oligosaccharides with terminal 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their non-reducing ends =

Synonyms

Hep III, HepA, heparin degrading enzyme, Heparin eliminase, heparin lyase, heparin lyase 1, heparin lyase I, heparin lyase II, Heparinase, heparinase I, heparinase II, heparitinase II, heparitinase III, HepI, HepII, HepP, HMPREF1016_02668, Lyase, heparin, PA14_23430, Pedsa_1818, PL12a

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.2 Acting on polysaccharides
                4.2.2.7 heparin lyase

Molecular Weight

Molecular Weight on EC 4.2.2.7 - heparin lyase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
111000
-
x * 111000, SDS-PAGE
111200
x * 111200, from amino acid sequence
23380
-
x * 24000, SDS-PAGE, x * 23380, mass spectrometry
24000
43000
45000
-
SDS-PAGE, Flavobacterium heparinum
48000
-
x * 48000, SDS-PAGE
50000
-
gel permeation chromatography, Flavobacterium heparinum
63000
-
SDS-PAGE, Bacteroides heparinolyticus
70000
-
gel filtration
70100
-
1 * 70100, SDS-PAGE
75670
-
mass spectrometry
85000
-
2 * 85000, calculated: 84545
85400
x * 85400, calculated