4.2.2.7: heparin lyase
This is an abbreviated version!
For detailed information about heparin lyase, go to the full flat file.
Word Map on EC 4.2.2.7
-
4.2.2.7
-
heparan
-
proteoglycans
-
glycosaminoglycans
-
chondroitinase
-
endothelial
-
chondroitin
-
oligosaccharide
-
disaccharide
-
anticoagulant
-
coagulation
-
flavobacterium
-
heparin-like
-
heparin-binding
-
antithrombin
-
dermatan
-
heparinum
-
protamine
-
clot
-
depolymerization
-
hyaluronic
-
hspgs
-
hyaluronidase
-
chlorate
-
lyases
-
n-sulfated
-
thromboplastin
-
glycocalyx
-
heparanase
-
iduronic
-
tetrasaccharide
-
thromboelastography
-
teg
-
atiii
-
anti-xa
-
6-o-sulfate
-
heparin-derived
-
o-sulfation
-
decasaccharide
-
analysis
-
thromboelastometry
-
lmwhs
-
heptose
-
enoxaparin
-
syndecan-4
-
tinzaparin
-
medicine
-
trisulfated
-
synthesis
-
heparinoids
-
kaolin
-
octasaccharide
-
polybrene
-
beta-vldl
- 4.2.2.7
- heparan
- proteoglycans
- glycosaminoglycans
- chondroitinase
- endothelial
- chondroitin
- oligosaccharide
- disaccharide
-
anticoagulant
-
coagulation
- flavobacterium
-
heparin-like
-
heparin-binding
- antithrombin
- dermatan
- heparinum
- protamine
- clot
-
depolymerization
-
hyaluronic
-
hspgs
- hyaluronidase
- chlorate
- lyases
-
n-sulfated
- thromboplastin
-
glycocalyx
- heparanase
-
iduronic
- tetrasaccharide
-
thromboelastography
- teg
-
atiii
-
anti-xa
-
6-o-sulfate
-
heparin-derived
-
o-sulfation
- decasaccharide
- analysis
-
thromboelastometry
- lmwhs
-
heptose
- enoxaparin
- syndecan-4
- tinzaparin
- medicine
-
trisulfated
- synthesis
-
heparinoids
- kaolin
- octasaccharide
- polybrene
-
beta-vldl
Reaction
Eliminative cleavage of polysaccharides containing (1->4)-linked D-glucuronate or L-iduronate residues and (1->4)-alpha-linked 2-sulfoamino-2-deoxy-6-sulfo-D-glucose residues to give oligosaccharides with terminal 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their non-reducing ends =
Synonyms
Hep III, HepA, heparin degrading enzyme, Heparin eliminase, heparin lyase, heparin lyase 1, heparin lyase I, heparin lyase II, Heparinase, heparinase I, heparinase II, heparitinase II, heparitinase III, HepI, HepII, HepP, HMPREF1016_02668, Lyase, heparin, PA14_23430, Pedsa_1818, PL12a
ECTree
4.2.2.7 heparin lyaseAdvanced search results
results (
results (Source Tissue
Source Tissue on EC 4.2.2.7 - heparin lyase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
SOURCE TISSUE 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
SOURCE
-
optimization of enzyme production, simple carbon sources, including sucrose, lactose, maltose, and complex carbon sources such as starch and cellulose are able to support growth of the organism, but enzyme can be produced only in the presence of maltose, sorbitol, mannitol, arabinose, and mannose. Phosphate inhibits enzyme production and cell growth, while heparin inhibits cell growth but is required for enzyme induction, overview. Heparinase production in optimized medium is highest, i.e., 75.4 units, when the pH of the medium is kept at pH 6.5, inoculum size of 0.5-1.0% of spore suspension, and for an incubation temperature of 30°C. Growth profile, heparin utilization, and heparinase production in optimized medium, overview
additional information
-
propagated in bovine lung microvascular endothelial cells
