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4.2.2.7: heparin lyase

This is an abbreviated version!
For detailed information about heparin lyase, go to the full flat file.

Word Map on EC 4.2.2.7

Reaction

Eliminative cleavage of polysaccharides containing (1->4)-linked D-glucuronate or L-iduronate residues and (1->4)-alpha-linked 2-sulfoamino-2-deoxy-6-sulfo-D-glucose residues to give oligosaccharides with terminal 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their non-reducing ends =

Synonyms

Hep III, HepA, heparin degrading enzyme, Heparin eliminase, heparin lyase, heparin lyase 1, heparin lyase I, heparin lyase II, Heparinase, heparinase I, heparinase II, heparitinase II, heparitinase III, HepI, HepII, HepP, HMPREF1016_02668, Lyase, heparin, PA14_23430, Pedsa_1818, PL12a

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.2 Acting on polysaccharides
                4.2.2.7 heparin lyase

Sequence

topprint

Sequence on EC 4.2.2.7 - heparin lyase

Please use the AA Sequence and Transmembrane Helices Search for a specific query.
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
HEPB_PEDHD
Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3)
772
0
87626
Swiss-Prot
-
HEP1_BACSE
12
0
1381
Swiss-Prot
-
HEP1_PEDHE
384
0
43807
Swiss-Prot
-
A0A4S2AZ73_9BACE
392
0
44368
TrEMBL
-
A0A5C6CYE7_9BACT
774
1
87034
TrEMBL
-
A0A222E3P1_9RHOB
773
0
87680
TrEMBL
-
A0A6N2VH20_9BACE
869
0
98920
TrEMBL
-
A0A645GHI1_9ZZZZ
242
0
27086
TrEMBL
other Location (Reliability: 5)
A0A5C5Y4C6_9PLAN
679
0
74183
TrEMBL
-
A0A380Z8U1_9BACE
394
1
44563
TrEMBL
-
A0A5C6CQ48_9BACT
912
1
102005
TrEMBL
-
E6SWQ9_BACT6
Bacteroides helcogenes (strain ATCC 35417 / DSM 20613 / JCM 6297 / CCUG 15421 / P 36-108)
386
0
44162
TrEMBL
-
A0A173WG86_9BACE
392
0
44207
TrEMBL
-
A0A1C6L426_9BACE
uncultured Bacteroides sp
389
0
44407
TrEMBL
-
A0A853SUY6_9BURK
1020
0
110210
TrEMBL
-
C6Y001_PEDHD
Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3)
384
0
43832
TrEMBL
-
A0A7W8QVZ8_9SPHI
772
0
87672
TrEMBL
-
A0A6N2RT90_BACUN
1117
1
127714
TrEMBL
-
A0A853SH34_9BURK
925
0
99365
TrEMBL
-
A0A853SV06_9BURK
958
0
103796
TrEMBL
-
A0A1V5UXT2_9BACT
1028
0
116680
TrEMBL
-
D0TT01_9BACE
381
0
43064
TrEMBL
-
C3QQD7_9BACE
381
0
43078
TrEMBL
-
A0A0P0GDH6_9BACE
868
0
98544
TrEMBL
-
A0A6N2VTD2_BACOV
392
0
44311
TrEMBL
-
A0A840CN47_9BACT
912
1
104765
TrEMBL
-
A0A518GDV8_9BACT
758
1
84386
TrEMBL
-
A0A108T7S0_BACSE
392
0
44378
TrEMBL
-
A0A174IIT5_BACUN
1117
1
127618
TrEMBL
-
A0A644VGT5_9ZZZZ
772
0
87953
TrEMBL
Secretory Pathway (Reliability: 1)
B3U3D9_PEDHE
363
0
41363
TrEMBL
-
A0A0P0FXV2_9BACE
389
0
44421
TrEMBL
-
A7M5V1_BACO1
Bacteroides ovatus (strain ATCC 8483 / DSM 1896 / JCM 5824 / BCRC 10623 / CCUG 4943 / NCTC 11153)
392
0
44342
TrEMBL
-
A0A449I501_9BACE
391
0
44738
TrEMBL
-
A0A174TD51_BACT4
392
0
44332
TrEMBL
-
W6KP76_MAGSQ
Magnetospira sp. (strain QH-2)
545
0
59096
TrEMBL
-
A0A0P0FQE7_BACT4
392
0
44316
TrEMBL
-
A0A5C6DPZ8_9BACT
642
0
70615
TrEMBL
-
A0A174S7P2_BACUN
330
0
37721
TrEMBL
-
A0A0P0FGF3_BACT4
873
1
100512
TrEMBL
-
A0A120A2Q3_BACSE
773
0
87872
TrEMBL
-
A0A840CXQ5_9BACE
392
0
44443
TrEMBL
-
A0A7J0AYT4_9BACT
Alistipes sp
877
1
100415
TrEMBL
-
C6Y1P2_PEDHD
Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3)
362
0
40862
TrEMBL
-
C9KZZ4_9BACE
392
0
44217
TrEMBL
-
A0A840CWZ1_9BACT
388
0
44417
TrEMBL
-
A0A1C5KYA4_9BACE
uncultured Bacteroides sp
408
0
46533
TrEMBL
-
A0A1V6FSI9_9BACT
1167
0
128619
TrEMBL
-
A0A120A181_BACSE
780
0
88318
TrEMBL
-
A0A137SJ78_9GAMM
667
0
76381
TrEMBL
-
E1AP31_BACSE
392
0
44290
TrEMBL
-
A0A0M2WUR3_9BURK
937
0
101589
TrEMBL
-
C3QK31_9BACE
398
0
44831
TrEMBL
-
A0A0B0EJL7_9BACT
847
1
95313
TrEMBL
-
C6IQ30_BACT4
392
0
44322
TrEMBL
-
A0A174Q9T7_BACUN
1117
1
127664
TrEMBL
-
A0A139KLB1_BACT4
392
0
44302
TrEMBL
-
A0A6N2VPE8_BACOV
873
1
100408
TrEMBL
-
A0A7J0A366_9BACE
877
1
100415
TrEMBL
-
A0A7R6P7K5_9GAMM
605
0
68808
TrEMBL
-
A0A7W8R0C3_9SPHI
384
0
43832
TrEMBL
-
F3ZPL4_9BACE
401
0
45455
TrEMBL
-
A0A6N2WC96_9BACE
392
0
44113
TrEMBL
-
A0A174U385_9BACE
392
0
44081
TrEMBL
-
A0A2N7RLJ2_9BURK
962
0
104126
TrEMBL
-
A0A6N2X1V3_9BACE
771
0
88357
TrEMBL
-
A0A6N2VIF4_9BACE
392
0
44959
TrEMBL
-
B0NW16_BACSE
392
0
44290
TrEMBL
-
A0A1C5PZ81_9BACE
uncultured Bacteroides sp
392
0
44168
TrEMBL
-
A0A0H2ZDM9_PSEAB
Pseudomonas aeruginosa (strain UCBPP-PA14)
550
0
61874
TrEMBL
-
C0JBW5_BACSE
773
0
87884
TrEMBL
-
E5X103_9BACE
773
0
87964
TrEMBL
-
F0S8P2_PSESL
Pseudopedobacter saltans (strain ATCC 51119 / DSM 12145 / JCM 21818 / CCUG 39354 / LMG 10337 / NBRC 100064 / NCIMB 13643)
655
0
76350
TrEMBL
-
Q8KKH9_NIACI
1050
0
116490
TrEMBL
-
O09496_9CAUD
632
0
66860
TrEMBL
-
Q89YQ6_BACTN
Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50)
376
0
42514
TrEMBL
-