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3.5.1.92: pantetheine hydrolase

This is an abbreviated version!
For detailed information about pantetheine hydrolase, go to the full flat file.

Word Map on EC 3.5.1.92

Reaction

(R)-pantetheine
+
H2O
=
(R)-pantothenate
 +
2-aminoethanethiol

Synonyms

GPI-80, PAGEL, pantetheinase, pantetheinase-associated gene expressed in leukocytes, pantetheinases, pantetheine hydrolase, vanin, vanin 1, vanin gene family, vanin-1, vanin-1 pantetheinase, vanin-2, vanin-3, vascular non-inflammatory molecule-1, vascular noninflammatory molecule 1, VNN-1, VNN1, Vnn1 pantetheinase, VNN2, VNN3

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.92 pantetheine hydrolase

Cloned

Cloned on EC 3.5.1.92 - pantetheine hydrolase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed in CHO cells
-
gene VNN-1, quantitative real-time RT-PCR expression analysis
gene Vnn1, quantitative RT-PCR enzyme expression analysis
gene vnn1, real-time quantitative PCR enzyme expression analysis
gene VNN2, semiquantitative RT-PCR expression analysis in ovulatory follicles and granulosa cells, DNA-binding activity of bovine VNN2 promoter, overview
stable expression of vanin-1 in HEK-293 cells
transient expression of soluble FLAG-tagged truncated enzyme mutant, and mutant enzymes E249Q and E439Q in HEK-293T cells
vanin-1 is highly expressed in liver and is under transcriptional control of PPAR-alpha and nutritional statu