3.5.1.92: pantetheine hydrolase
This is an abbreviated version!
For detailed information about pantetheine hydrolase, go to the full flat file.
Word Map on EC 3.5.1.92
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3.5.1.92
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cysteamine
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pantothen
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gpi-anchored
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ectoenzyme
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pantothenamides
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gelatinase-associated
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walter
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aminothiol
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pantethine
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biotinidase
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julius
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medicine
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diagnostics
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drug development
- 3.5.1.92
- cysteamine
-
pantothen
-
gpi-anchored
-
ectoenzyme
- pantothenamides
-
gelatinase-associated
-
walter
-
aminothiol
- pantethine
- biotinidase
-
julius
- medicine
- diagnostics
- drug development
Reaction
Synonyms
GPI-80, PAGEL, pantetheinase, pantetheinase-associated gene expressed in leukocytes, pantetheinases, pantetheine hydrolase, vanin, vanin 1, vanin gene family, vanin-1, vanin-1 pantetheinase, vanin-2, vanin-3, vascular non-inflammatory molecule-1, vascular noninflammatory molecule 1, VNN-1, VNN1, Vnn1 pantetheinase, VNN2, VNN3
ECTree
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Localization
Localization on EC 3.5.1.92 - pantetheine hydrolase
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an highly sensitive fluorescent assay using a novel fluorescent pantotheine derivative is used for characterization of a soluble version of human vanin-1 recombinant protein, identification of hits from high-throughput screening, and quantification of vanin pantotheinase acitivity in cell lines and tissues
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additional information
a glycosylphosphatidylinositol (GPI)-anchored ectoenzyme
pantetheinase is an ectoenzyme that is attached to the outer plasma membrane by a glycosylphosphatidylinositol (GPI) anchor. GPI anchors consist of three domains: a phosphoethanolamine linker that attaches to the C terminal end of the target protein, a conserved glycan core and a phospholipid tail for anchoring to the lipid membrane
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pantetheinase is an ectoenzyme that is attached to the outer plasma membrane by a glycosylphosphatidylinositol (GPI) anchor. GPI anchors consist of three domains: a phosphoethanolamine linker that attaches to the C terminal end of the target protein, a conserved glycan core and a phospholipid tail for anchoring to the lipid membrane
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the purified recombinant vanin-1 consists of a extracellular portion without a glycosylphosphatidylinositol linker
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a glycosylphosphatidylinositol-anchored membrane pantetheinase
vanin 1 is membrane-associated via a glycosylphosphatidylinositol (GPI)-anchor, though soluble enzyme forms are detected as well
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additional information
vanin 1 is membrane-associated via a glycosylphosphatidylinositol (GPI)-anchor, though soluble enzyme forms are detected as well
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