3.4.24.83: anthrax lethal factor endopeptidase
This is an abbreviated version!
For detailed information about anthrax lethal factor endopeptidase, go to the full flat file.
Word Map on EC 3.4.24.83
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3.4.24.83
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edema
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spore
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intoxication
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endosomal
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exotoxin
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metalloprotease
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inhalation
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inflammasome
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endocytosis
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toxin-induced
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anti-pa
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heptameric
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caspase-1
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sterne
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furin
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mapkks
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lt-induced
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tripartite
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diphtheria
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toxin-mediated
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spore-forming
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pyroptosis
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toxemia
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ring-shaped
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receptor-bound
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toxin-neutralizing
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zinc-dependent
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molecular biology
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cytolysis
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pa-binding
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medicine
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mkk
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bioterrorism
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diagnostics
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toxin-sensitive
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synthesis
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postexposure
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cell-binding
- 3.4.24.83
-
edema
- spore
-
intoxication
- endosomal
-
exotoxin
- metalloprotease
-
inhalation
- inflammasome
-
endocytosis
-
toxin-induced
-
anti-pa
-
heptameric
- caspase-1
- sterne
- furin
- mapkks
-
lt-induced
-
tripartite
- diphtheria
-
toxin-mediated
-
spore-forming
-
pyroptosis
- toxemia
-
ring-shaped
-
receptor-bound
-
toxin-neutralizing
-
zinc-dependent
- molecular biology
-
cytolysis
-
pa-binding
- medicine
- mkk
-
bioterrorism
- diagnostics
-
toxin-sensitive
- synthesis
-
postexposure
-
cell-binding
Reaction
Preferred amino acids around the cleavage site can be denoted BBBBxHx-/-H, in which B denotes Arg or Lys, H denotes a hydrophobic amino acid, and x is any amino acid. The only known protein substrates are mitogen-activated protein (MAP) kinase kinases =
Synonyms
anthrax lethal factor, anthrax lethal factor protease, anthrax lethal toxin, anthrax LF, anthrax toxin lethal factor, Bacillus anthracis lethal toxin, lethal factor, lethal factor of anthrax toxin, lethal toxin, LeTx, LF, LTx
ECTree
3.4.24.83 anthrax lethal factor endopeptidaseAdvanced search results
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results (Synonyms
Synonyms on EC 3.4.24.83 - anthrax lethal factor endopeptidase
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
anthrax lethal factor
anthrax lethal toxin
lethal factor
lethal factor of anthrax toxin
the C-terminal region carries out the metalloprotease activity, while the N-terminal domain (residues 1-288) is responsible for protective antigen binding
lethal toxin
LeTx
LF
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anthrax lethal factor
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anthrax lethal factor
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anthrax lethal factor along with its receptor-binding partner protective antigen forms anthrax lethal toxin
anthrax lethal factor
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anthrax lethal factor is part of the bipartite anthrax lethal toxin
anthrax lethal toxin
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anthrax lethal toxin
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the pathological actions of anthrax toxin require the activities of its edema factor and lethal factor enzyme components which gain intracellular access via its receptor-binding component, protective antigen
anthrax lethal toxin
protective antigen plus lethal factor makes lethal toxin
lethal factor
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lethal factor combines with protective antigen to form antrax lethal toxin
lethal factor
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lethal toxin is secreted by Bacillus anthracis as a bipartite toxin consisting of protective antigen (PA) and lethal factor (LF)
lethal toxin
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LeTx
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LeTx
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lethal toxin is composed of lethal factor and the protective antigen
LeTx
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protective antigen from Bacillus anthracis binds to cellular receptors, combines with lethal factor forming lethal toxin LeTx, and facilitates the translocation of lethal factor into the cytosol
LeTx
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protective antigen from Bacillus anthracis binds to cellular receptors, combines with lethal factor forming lethal toxin LeTx, and facilitates the translocation of lethal factor into the cytosol
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