3.4.21.B28: fibroblast activation protein alpha subunit
This is an abbreviated version!
For detailed information about fibroblast activation protein alpha subunit, go to the full flat file.
Word Map on EC 3.4.21.B28
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3.4.21.B28
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polyposis
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adenomatous
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colorectal
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apc
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polyneuropathy
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adenoma
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polyp
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amyloid
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amyloidotic
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transthyretin
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hereditary
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germline
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colectomy
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surveillance
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endoscopic
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bowel
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desmoids
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anastomosis
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abdominal
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proctocolectomy
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duodenal
-
ileal
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prophylactic
-
pouch
-
extracolonic
-
amyloidogenic
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ileostomy
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val30met
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rectum
-
gardner
-
colonoscopy
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pouch-anal
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hnpcc
-
sulindac
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pancreaticoduodenectomy
-
amyloidoses
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hamartomatous
-
periampullary
-
lynch
-
ampullary
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diagnostics
-
mutyh
-
domino
-
polypectomy
-
tafamidis
-
fundic
-
adenoma-carcinoma
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prealbumin
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peutz-jeghers
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medicine
-
fibromatosis
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nonpolyposis
- 3.4.21.B28
- polyposis
-
adenomatous
- colorectal
- apc
- polyneuropathy
- adenoma
- polyp
-
amyloid
-
amyloidotic
- transthyretin
- hereditary
-
germline
-
colectomy
-
surveillance
-
endoscopic
- bowel
- desmoids
-
anastomosis
- abdominal
-
proctocolectomy
- duodenal
- ileal
-
prophylactic
-
pouch
-
extracolonic
-
amyloidogenic
-
ileostomy
-
val30met
- rectum
-
gardner
-
colonoscopy
-
pouch-anal
-
hnpcc
- sulindac
-
pancreaticoduodenectomy
- amyloidoses
-
hamartomatous
-
periampullary
-
lynch
-
ampullary
- diagnostics
-
mutyh
-
domino
-
polypectomy
-
tafamidis
-
fundic
-
adenoma-carcinoma
-
prealbumin
-
peutz-jeghers
- medicine
- fibromatosis
- nonpolyposis
Reaction
fibroblast activation protein requires substrates with Pro at P1 and Gly or D-amino acids at P2. Met-alpha2-antiplasmin is cleaved N-terminally at Pro3-Leu4 and Pro12-Asn13 into Asn-alpha2-antiplasmin that is rapidly cross-linked to fibrin and protects it from digestion by plasmin =
Synonyms
antiplasmin-cleaving enzyme, APCE, FAP, FAP-alpha, FAP-specific protease, FAPalpha, fibroblast activation factor, fibroblast activation protein, fibroblast activation protein alpha, fibroblast activation protein protease, fibroblast activation protein-alpha, fibroblast activation protein-specific protease, gelatinase, S09.007, seprase, surface expressed protease, type II transmembrane serine protease, Z-Pro-prolinal-insensitive peptidase, ZIP