3.4.21.B28: fibroblast activation protein alpha subunit

This is an abbreviated version!
For detailed information about fibroblast activation protein alpha subunit, go to the full flat file.

Word Map on EC 3.4.21.B28

3.4.21.B28

polyposis

adenomatous

colorectal

apc

polyneuropathy

adenoma

polyp

amyloid

amyloidotic

transthyretin

hereditary

germline

colectomy

surveillance

endoscopic

bowel

desmoids

anastomosis

abdominal

proctocolectomy

duodenal

ileal

prophylactic

pouch

extracolonic

amyloidogenic

ileostomy

val30met

rectum

gardner

colonoscopy

pouch-anal

hnpcc

sulindac

pancreaticoduodenectomy

amyloidoses

hamartomatous

periampullary

lynch

ampullary

diagnostics

mutyh

domino

polypectomy

tafamidis

fundic

adenoma-carcinoma

prealbumin

peutz-jeghers

medicine

fibromatosis

nonpolyposis

Reaction

fibroblast activation protein requires substrates with Pro at P1 and Gly or D-amino acids at P2. Met-alpha2-antiplasmin is cleaved N-terminally at Pro3-Leu4 and Pro12-Asn13 into Asn-alpha2-antiplasmin that is rapidly cross-linked to fibrin and protects it from digestion by plasmin =

Synonyms

antiplasmin-cleaving enzyme, APCE, FAP, FAP-alpha, FAP-specific protease, FAPalpha, fibroblast activation factor, fibroblast activation protein, fibroblast activation protein alpha, fibroblast activation protein protease, fibroblast activation protein-alpha, fibroblast activation protein-specific protease, gelatinase, S09.007, seprase, surface expressed protease, type II transmembrane serine protease, Z-Pro-prolinal-insensitive peptidase, ZIP

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.21 Serine endopeptidases

3.4.21.B28 fibroblast activation protein alpha subunit

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
1	Activating Compound
4	AA Sequence
11	Application
1	CAS Registry Number
15	Cloned(Commentary)
1	Crystallization (Commentary)
9104	Disease/ Diagnostics
1	Expression
15	General Information
40	IC50 Value
122	Inhibitors
1	kcat/KM [mM/s]
51	Ki Value [mM]
93	KM Value [mM]
23	Localization
31	Molecular Weight [Da]
34	Natural Substrates/ Products (Substrates)
193	Organism
7	pH Optimum
2	pI Value
9	Posttranslational Modification
28	Protein Variants
14	Purification (Commentary)
4	Reaction
12	Reaction Type
54	Reference
124	Source Tissue
171	Substrates and Products (Substrate)
15	Subunits
111	Synonyms
3	Temperature Optimum [°C]
80	Turnover Number [1/s]

Molecular Weight

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Molecular Weight on EC 3.4.21.B28 - fibroblast activation protein alpha subunit

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide

Go to Molecular Weight Search

100000

Homo sapiens

2 * 100000, multiangle light scattering in combination with gel filtration chromatography and interferometric refractometry

680739

105000

Homo sapiens

1 * 95000 + 1 * 105000, SDS-PAGE

650762, 651537

153000

Homo sapiens

recombinant FAP, gel filtration

160000

160000 - 170000

170000

175000

native APCE, gel filtration

678908

200000

Homo sapiens

multiangle light scattering in combination with gel filtration chromatography and interferometric refractometry

680739

215000

Homo sapiens

SDS-PAGE under nonreducing conditions

400000

87720

subunit, calculated from amino acid sequence

650283

90000

Homo sapiens

theoretical value of FAPalpha-His6tag

674436

93000

Homo sapiens

2 * 93000, recombinant FAP, SDS-PAGE

95000

96000

97000