3.4.21.94: proprotein convertase 2

This is an abbreviated version!
For detailed information about proprotein convertase 2, go to the full flat file.

Reaction

release of protein hormones and neuropeptides from their precursors, generally by hydrolysis of -Lys-Arg-/- bonds =

Synonyms

EGL-3/KPC2, More, Neuroendocrine convertase 2, PC2, PC2-like enzyme, PCSK2, pro-protein convertase-2, pro-protein convertase-2/carboxypeptidase-E, prohormone convertase, prohormone convertase 2, prohormone convertase-2, proneuropeptide convertase 2, proprotein convertase 2, proprotein convertase subtilisin/kexin-type 2

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.21 Serine endopeptidases

                3.4.21.94 proprotein convertase 2

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Results	in table
3	Activating Compound
31	AA Sequence
7	Application
3	CAS Registry Number
18	Cloned(Commentary)
96	Disease/ Diagnostics
5	Expression
8	General Information
16	Inhibitors
9	Ki Value [mM]
13	KM Value [mM]
2	Localization
3	Metals/Ions
7	Molecular Weight [Da]
11	Natural Substrates/ Products (Substrates)
62	Organism
7	pH Optimum
3	pH Range
1	pI Value
2	Posttranslational Modification
18	Protein Variants
5	Purification (Commentary)
3	Reaction
1	Reaction Type
49	Reference
61	Source Tissue
1	Specific Activity [micromol/min/mg]
64	Substrates and Products (Substrate)
5	Subunits
64	Synonyms
3	Temperature Optimum [°C]
1	Temperature Stability [°C]
8	Turnover Number [1/s]

Synonyms

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Synonyms on EC 3.4.21.94 - proprotein convertase 2

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SYNONYM

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

EGL-3/KPC2

2 entries

Neuroendocrine convertase 2

-

-

-

-

PC2

7 entries

PC2-like enzyme

Haliotis asinina

B2ZSS9

-

708778

PCSK2

2 entries

pro-protein convertase-2

Rattus norvegicus

-

-

710101

pro-protein convertase-2/carboxypeptidase-E

Rattus norvegicus

-

-

710101

prohormone convertase

Mus musculus

-

-

669378

prohormone convertase 2

4 entries

prohormone convertase-2

Mus musculus

-

-

688525, 709603

proneuropeptide convertase 2

Mus musculus

-

-

689212

proprotein convertase 2

Rattus norvegicus

-

-

689214, 709250

proprotein convertase subtilisin/kexin-type 2

Homo sapiens

-

-

689018

additional information

Mus musculus

-

the enzyme belongs to the proprotein protease family of mammalian calcium-dependent serine proteases

669378

EGL-3/KPC2

Caenorhabditis elegans

-

-

688526

EGL-3/KPC2

Caenorhabditis elegans N2

-

-

-

PC2

-

-

-

-

PC2

Haliotis asinina

B2ZSS9

-

708778

PC2

Homo sapiens

-

-

653858, 668083, 669843, 682808, 688466, 717906

PC2

Mus musculus

-

-

653858, 668377, 668422, 669378, 669436, 670480, 677957, 686302, 686303, 688466, 688525, 689212, 700298, 709603, 717856

PC2

Mus musculus

P21661

-

753696

PC2

Oryzias latipes

-

-

668720

PC2

Rattus norvegicus

-

-

653858, 669626, 683932, 688466, 689214, 700473, 709250, 710101

PCSK2

Homo sapiens

-

-

689018

PCSK2

Mus musculus

P21661

-

753499

prohormone convertase 2

Haliotis asinina

B2ZSS9

-

708778

prohormone convertase 2

Homo sapiens

-

-

653858, 682808, 717906

prohormone convertase 2

Mus musculus

-

-

653858, 668377, 669436, 670480, 677957, 686302, 686303, 717856

prohormone convertase 2

Rattus norvegicus

-

-

653858, 669626, 683932