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3.4.21.94: proprotein convertase 2

This is an abbreviated version!
For detailed information about proprotein convertase 2, go to the full flat file.

Word Map on EC 3.4.21.94

Reaction

release of protein hormones and neuropeptides from their precursors, generally by hydrolysis of -Lys-Arg-/- bonds =

Synonyms

EGL-3/KPC2, More, Neuroendocrine convertase 2, PC2, PC2-like enzyme, PCSK2, pro-protein convertase-2, pro-protein convertase-2/carboxypeptidase-E, prohormone convertase, prohormone convertase 2, prohormone convertase-2, proneuropeptide convertase 2, proprotein convertase 2, proprotein convertase subtilisin/kexin-type 2

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.94 proprotein convertase 2

Sequence

Sequence on EC 3.4.21.94 - proprotein convertase 2

Please use the AA Sequence and Transmembrane Helices Search for a specific query.
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
NEC2_BOVIN
638
0
70247
Swiss-Prot
Secretory Pathway (Reliability: 3)
NEC2_CAEEL
652
0
72046
Swiss-Prot
Secretory Pathway (Reliability: 1)
NEC2_HUMAN
638
0
70565
Swiss-Prot
Secretory Pathway (Reliability: 2)
NEC2_MOUSE
637
0
70785
Swiss-Prot
Secretory Pathway (Reliability: 2)
NEC2_PIG
638
0
70452
Swiss-Prot
Secretory Pathway (Reliability: 2)
NEC2_PONAB
638
0
70566
Swiss-Prot
Secretory Pathway (Reliability: 2)
NEC2_RAT
637
0
70753
Swiss-Prot
Secretory Pathway (Reliability: 2)
W1ILL9_9GAMM
2229
0
235507
TrEMBL
-
Q963F2_HETGL
671
1
74163
TrEMBL
Secretory Pathway (Reliability: 1)
B2ZRZ7_DERVA
654
0
72036
TrEMBL
Secretory Pathway (Reliability: 2)
A0A7R8D220_LEPSM
738
0
82360
TrEMBL
Mitochondrion (Reliability: 5)
B7Q266_IXOSC
430
0
46915
TrEMBL
other Location (Reliability: 2)
A0A812BXB2_SEPPH
875
14
100642
TrEMBL
Secretory Pathway (Reliability: 5)
E0VP88_PEDHC
574
0
63522
TrEMBL
other Location (Reliability: 5)
A0A8B6CXZ0_MYTGA
342
0
37737
TrEMBL
Secretory Pathway (Reliability: 2)
A0A8B6DLX1_MYTGA
189
0
19869
TrEMBL
Secretory Pathway (Reliability: 2)
A0JP87_XENTR
639
1
70587
TrEMBL
Secretory Pathway (Reliability: 1)
A0A8B6CUY1_MYTGA
364
0
40173
TrEMBL
other Location (Reliability: 1)
A0A6J7ZZQ3_MYTCO
323
0
36068
TrEMBL
other Location (Reliability: 5)
A0A6J8C7C0_MYTCO
652
0
72580
TrEMBL
Secretory Pathway (Reliability: 1)
D3VLC5_XENNA
Xenorhabdus nematophila (strain ATCC 19061 / DSM 3370 / CCUG 14189 / LMG 1036 / NCIMB 9965 / AN6)
1751
0
182733
TrEMBL
-
Q6GLS0_XENLA
639
0
70523
TrEMBL
Secretory Pathway (Reliability: 1)
C1LEI4_SCHJA
552
1
61003
TrEMBL
Secretory Pathway (Reliability: 3)
A0A8B6DKM9_MYTGA
162
0
16893
TrEMBL
other Location (Reliability: 2)
A0A8B6CHT3_MYTGA
615
1
67207
TrEMBL
other Location (Reliability: 2)
A0A8M1NSS0_DANRE
646
1
71779
TrEMBL
Secretory Pathway (Reliability: 2)
B0SQU9_LEPBP
Leptospira biflexa serovar Patoc (strain Patoc 1 / ATCC 23582 / Paris)
563
0
59888
TrEMBL
-
A1IHD0_CIOIN
660
0
72590
TrEMBL
Secretory Pathway (Reliability: 4)
B2ZSS9_HALAI
662
0
73273
TrEMBL
-
I6M2I5_PENMO
633
0
70405
TrEMBL
-