Literature summary for 3.4.21.94 extracted from

Croissandeau, G.; Wahnon, F.; Yashpal, K.; Seidah, N.G.; Coderre, T.J.; Chretien, M.; Mbikay, M.
Increased stress-induced analgesia in mice lacking the proneuropeptide convertase PC2 (2006), Neurosci. Lett., 406, 71-75.

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Protein Variants

Protein Variants	Comment	Organism
additional information	in PC2-null mice, basal responses and responses after a cold swim are similar to wild-type mice. After a short forced swim in warm water, PC2-null mice are significantly less responsive to the stimuli than wild-type mice, an indication of increased opioid-mediated stress-induced analgesia. Enhanced analgesia in PC2-null mice may be caused by an accumulation of opioid precursor processing intermediates with potent analgesic effects, or by loss of anti-opioid peptides	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	CD-1 genetic background	-

Synonyms

Synonyms	Comment	Organism
PC2	-	Mus musculus
proneuropeptide convertase 2	-	Mus musculus

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Release 2023.1 (January 2023)