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3.4.21.27: coagulation factor XIa

This is an abbreviated version!
For detailed information about coagulation factor XIa, go to the full flat file.

Word Map on EC 3.4.21.27

Reaction

Selective cleavage of Arg-/-Ala and Arg-/-Val bonds in factor IX to form factor IXa =

Synonyms

activated blood-coagulation factor XI, activated coagulation factor XIa, activated factor XI, activated factor XIa, activated FXI, activated plasma thromboplastin antecedent, blood coagulation factor XIa, blood-coagulation factor XI, activated, blood-coagulation factor XIa, coagulation factor XI, coagulation factor XIa, factor XI, factor XIa, factor XIa catalytic domain, FXI, FXIa, fXIaCD, More, plasma thromboplastin antecedent, prolyl endopeptidase, protease factor XIa, PTA, recombinant human FXI370-607, rhFXI370-607

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.27 coagulation factor XIa

Molecular Weight

Molecular Weight on EC 3.4.21.27 - coagulation factor XIa

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
136100
-
nonglycosylated, cysteinylated FXI dimer, MALDI-TOF mass spectrometry
146400
-
FXI, SDS-PAGE
160000
30000
-
method not mentioned
35000
-
x * 35000, x * 48000, SDS-PAGE, 2 chains
362500
catalytic domain, wild-type, SDS-PAGE
48000
-
x * 35000, x * 48000, SDS-PAGE, 2 chains
68000
-
2 * 68000, SDS-PAGE
72626
-
1 * 72626, mutant FXI/G326C, SDS-PAGE
72630
-
mutant FXI/G326C, SDS-PAGE
73210
-
2 * 73210, FXI, SDS-PAGE
79600
-
1 * 79600, SDS-PAGE
80000
85600
-
gel filtration