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Disease on EC 3.4.21.27 - coagulation factor XIa

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DISEASE
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Abnormalities, Multiple
Deep venous thrombosis treated by rivaroxaban in a young patient with type Ia carbohydrate-deficient glycoprotein (CDG) syndrome.
Abortion, Habitual
Pregnancy in women with von Willebrand's disease or factor XI deficiency.
Abortion, Spontaneous
Activity of coagulation factor XI in patients with spontaneous miscarriage: The presence of risk alleles.
High factor XI, recurrent pregnancy loss, enoxaparin.
Pregnancy outcome in Factor XI deficiency: incidence of miscarriage, antenatal and postnatal haemorrhage in 33 women with Factor XI deficiency.
Abortion, Threatened
Pregnancy in women with von Willebrand's disease or factor XI deficiency.
Acute Coronary Syndrome
Activated factor XI and tissue factor in chronic obstructive pulmonary disease: links with inflammation and thrombin generation.
Active tissue factor and activated factor XI in circulating blood of patients with systolic heart failure due to ischemic cardiomyopathy.
Factor XIa and Thrombin Generation Are Elevated in Patients with Acute Coronary Syndrome and Predict Recurrent Cardiovascular Events.
Factors associated with the presence of circulating active tissue factor and activated factor XI in stable angina patients.
Myocardial infarctions and other acute coronary syndromes in rare congenital bleeding disorders: a critical analysis of all reported cases.
Adenocarcinoma
Engineering a thermostable human prolyl endopeptidase for antibody-directed enzyme prodrug therapy.
Adenoma
The factor of factor XI deficiency in thyroid neoplasia.
Afibrinogenemia
Arterial and venous thrombosis in rare congenital bleeding disorders: a critical review.
Autosomal recessive inherited bleeding disorders in Pakistan: a cross-sectional study from selected regions.
Congenital hemorrhagic disorders in Jordan.
Menorrhagia and reproductive health in rare bleeding disorders: a study from the Indian subcontinent.
Unprovoked Pulmonary Embolism in Factor VII Deficiency.
Agranulocytosis
Acquired agranulocytosis and factor XI deficiency in association with thymoma.
alpha 1-Antitrypsin Deficiency
Alpha 1 antitrypsin deficiency and plasma thromboplastin antecedent deficiency--a new association?
Alzheimer Disease
4-Methyltetrahydropyran as a Convenient Alternative Solvent for Olefin Metathesis Reaction: Model Studies and Medicinal Chemistry Applications.
A novel prolyl endopeptidase inhibitor, JTP-4819, with potential for treating Alzheimer's disease.
A novel prolyl endopeptidase inhibitor, JTP-4819--its behavioral and neurochemical properties for the treatment of Alzheimer's disease.
Brain prolyl endopeptidase expression in aging, APP transgenic mice and Alzheimer's disease.
In silico methods to identify meat-derived prolyl endopeptidase inhibitors.
Increased Levels of Coagulation Factor XI in Plasma Are Related to Alzheimer's Disease Diagnosis.
Plant phenolics as prolyl endopeptidase inhibitors.
SERPIN regulation of factor XIa. The novel observation that protease nexin 1 in the presence of heparin is a more potent inhibitor of factor XIa than C1 inhibitor.
Tryptophan-Containing Dual Neuroprotective Peptides: Prolyl Endopeptidase Inhibition and Caenorhabditis elegans Protection from ?-Amyloid Peptide Toxicity.
Amnesia
Protective effect of eurystatins A and B, new prolyl endopeptidase inhibitors, on scopolamine-induced amnesia in rats.
Amyloidosis
Misfolded proteins activate factor XII in humans, leading to kallikrein formation without initiating coagulation.
The elusive physiologic role of Factor XII.
Amyotrophic Lateral Sclerosis
Therapeutic uses of microencapsulated genetically engineered cells.
Anaphylaxis
Blood derived products in pediatrics: New laboratory tools for optimizing potency assignment and reducing side effects.
Anemia
[Plasma thromboplastin antecedent deficiency anemia.]
Angina, Stable
Active tissue factor and activated factor XI in circulating blood of patients with systolic heart failure due to ischemic cardiomyopathy.
Factors associated with the presence of circulating active tissue factor and activated factor XI in stable angina patients.
Angioedema
Lisinopril-Induced Angioedema in a Patient with Plasma Prekallikrein Deficiency.
Angioedemas, Hereditary
Complexes between C1-inhibitor, kallikrein, high molecular weight kininogen, plasma thromboplastin antecedent, and plasmin in normal human plasma and hereditary angioneurotic edema plasmas containing dysmorphic C1-inhibitors: role of cold activation.
Prekallikrein activation and high-molecular-weight kininogen consumption in hereditary angioedema.
The inhibitory properties of plasma against activated plasma thromboplastin antecedent (factor XIa) in hereditary angioneurotic edema.
Antiphospholipid Syndrome
Factor XI is a substrate for oxidoreductases: Enhanced activation of reduced FXI and its role in antiphospholipid syndrome thrombosis.
Myocardial infarction in a patient with factor XI deficiency and a lupus anticoagulant.
Successful Peritoneal Dialysis Catheter Placement in a New End-Stage Renal Disease Patient with Combined Antiphospholipid Syndrome and Factor XI Deficiency.
Aortic Valve Stenosis
Activated factor XI and tissue factor in aortic stenosis: links with thrombin generation.
Arteriovenous Fistula
[Acquired factor XI inhibitor and chronic lymphocytic leukemia.]
Arthritis
Severe Ankle Arthritis After Multiple Hemarthrosis Secondary to Factor XI Deficiency: A Case Report.
Arthritis, Gouty
The inflammatory process in acute gouty arthritis. II. The presence of Hageman factor and plasma thromboplastin antecedent in synovial fluid.
Arthritis, Juvenile
Factor XI deficiency, juvenile rheumatoid arthritis and systemic lupus erythematosus. Report of the first case.
Arthritis, Rheumatoid
Activities of dipeptidyl peptidase II, dipeptidyl peptidase IV, prolyl endopeptidase, and collagenase-like peptidase in synovial membrane from patients with rheumatoid arthritis and osteoarthritis.
Atherosclerosis
Factor XI Deficiency Protects Against Atherogenesis in Apolipoprotein E/Factor XI Double Knockout Mice.
Lack of association of plasma factor XI with incident stroke and coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) Study.
Pharmacological targeting of coagulation factor XI mitigates the development of experimental atherosclerosis in low-density lipoprotein receptor-deficient mice.
Atrial Fibrillation
Activated factor IX, factor XI and tissue factor identify patients with permanent atrial fibrillation treated with warfarin who are at risk of ischemic stroke.
Stroke Prevention in Atrial Fibrillation: Looking Forward.
The role of haematological traits in risk of ischaemic stroke and its subtypes.
Autoimmune Diseases
The concept and classification of antiphospholipid/cofactor syndromes.
Bacteremia
Activation and inhibition of Hageman factor-dependent pathways and the complement system in uncomplicated bacteremia or bacterial shock.
Bernard-Soulier Syndrome
Autosomal recessive inherited bleeding disorders in Pakistan: a cross-sectional study from selected regions.
Clinical and laboratory features of 178 children with recurrent epistaxis.
Co-existence of Bernard Soulier syndrome and factor XI deficiency in a family: a unified pathology?
Menorrhagia and reproductive health in rare bleeding disorders: a study from the Indian subcontinent.
Novel genetic abnormalities in Bernard-Soulier syndrome in India.
The spectrum of bleeding disorders in women with menorrhagia: a report from Western India.
Blindness
Late retrobulbar hemorrhage and blindness following malar fracture complicated by factor XI deficiency.
Blood Coagulation Disorders, Inherited
A novel heterozygous missense mutation (His127Arg) in a family with inherited cross-reacting material positive factor XI deficiency.
Acquired Factor XI Deficiency: A Rare Complication After Liver Transplantation.
Factor XI deficiency and obstetrical anesthesia.
Factor XI deficiency disclosed following haemorrhage related to a dental extraction. Brief review and case report.
Factor XI gene mutations in factor XI deficient patients of the Czech Republic.
Identification of carriers of the mutation causing coagulation factor XI deficiency in Polish Holstein-Friesian cattle.
The use of desmopressin in congenital factor XI deficiency: a systematic review.
[Anesthesia and perioperative management for cesarean section in patient with factor XI deficiency: a case report].
[Familial study of factor XI deficiency. Presurgical prophylactic treatment with desmopressin plus antifibrinolytics]
[Use of recombinant, activated Factor VII in the treatment and prevention of bleeding complications in two female patients suffering from congenital XI factor deficiency during orthopedic and traumatology intervention. Case reports]
Blood Platelet Disorders
[Thrombocytopenic thrombocytopathy in a case of factor XI deficiency]
Bloom Syndrome
Comprehensive arrayed primer extension array for the detection of 59 sequence variants in 15 conditions prevalent among the (Ashkenazi) Jewish population.
Brain Injuries, Traumatic
The Formation of Microthrombi in Parenchymal Microvessels after Traumatic Brain Injury Is Independent of Coagulation Factor XI.
Brain Neoplasms
Recombinant factor VIIa for the prophylaxis of perioperative hemorrhage in a patient with congenital factor XI deficiency undergoing brain tumor neurosurgery.
Canavan Disease
Comprehensive arrayed primer extension array for the detection of 59 sequence variants in 15 conditions prevalent among the (Ashkenazi) Jewish population.
Carcinoma
Cloning and characterization of the human factor XI gene promoter: transcription factor hepatocyte nuclear factor 4alpha (HNF-4alpha ) is required for hepatocyte-specific expression of factor XI.
Plasma activity of prolyl endopeptidase in relation to psychopathology during immunotherapy with IFN-alpha in patients with renal cell carcinoma.
Studies on a circulating anticoagulant inhibiting factor XI in a patient with congenital deficiency and carcinoma of the prostate.
Carcinoma, Renal Cell
Plasma activity of prolyl endopeptidase in relation to psychopathology during immunotherapy with IFN-alpha in patients with renal cell carcinoma.
Cardiomyopathies
Active tissue factor and activated factor XI in circulating blood of patients with systolic heart failure due to ischemic cardiomyopathy.
Cardiovascular Diseases
Activated factor IX, factor XI and tissue factor identify patients with permanent atrial fibrillation treated with warfarin who are at risk of ischemic stroke.
Clinical experience of factor XI deficiency: the role of fresh frozen plasma and factor XI concentrate.
Elevated factor XI activity levels are associated with an increased odds ratio for cerebrovascular events.
Elevated levels of Factor XI are associated with cardiovascular disease in women.
The plasma kallikrein-kinin system and risk of cardiovascular disease in men.
Thromboembolic phenomena in patients with hereditary factor XI deficiency.
Catalepsy
[Neuroleptic catalepsy in rats is accompanied by activation of brain prolyl endopeptidase and is eliminated by inhibitors of this enzyme]
Cataract
Cataract Extraction Without Prophylactic Treatment in Patients With Severe Factor XI Deficiency.
Diagnosis of Factor XI deficiency following congenital cataract extraction.
Ophthalmic surgery and plasma thromboplastin antecedent (factor XI) deficiency.
Proteases in the Emory mouse cataract.
[Cataract surgery with congenital factor XI deficiency: a case report]
Celiac Disease
A new microbial gluten-degrading prolyl endopeptidase: Potential application in celiac disease to reduce gluten immunogenic peptides.
Development of wheat genotypes expressing a glutamine-specific endoprotease from barley and a prolyl endopeptidase from Flavobacterium meningosepticum or Pyrococcus furiosus as a potential remedy to celiac disease.
Effect of pretreatment of food gluten with prolyl endopeptidase on gluten-induced malabsorption in celiac sprue.
Fermentation, purification, formulation, and pharmacological evaluation of a prolyl endopeptidase from Myxococcus xanthus: implications for Celiac Sprue therapy.
No genetic association of the human prolyl endopeptidase gene in the Dutch celiac disease population.
Structural basis for gluten intolerance in celiac sprue.
Targeted modification of wheat grain protein to reduce the content of celiac causing epitopes.
Cerebral Hemorrhage
A surgical case of cerebral hemorrhage in a patient with factor XI deficiency.
Cerebral Hemorrhage, Traumatic
First case of delayed traumatic intracerebral hemorrhage in a patient with undiagnosed factor XI deficiency: diagnosis and management review.
Citrullinemia
A Review of Selected Genes with Known Effects on Performance and Health of Cattle.
coagulation factor ixa deficiency
Activation of factor IX by the reaction product of tissue factor and factor VII: additional pathway for initiating blood coagulation.
Activation of factor VII during alimentary lipemia occurs in healthy adults and patients with congenital factor XII or factor XI deficiency, but not in patients with factor IX deficiency.
Clinical and laboratory features of 178 children with recurrent epistaxis.
Fibrin formation, fibrinopeptide A release, and platelet thrombus dimensions on subendothelium exposed to flowing native blood: greater in factor XII and XI than in factor VIII and IX deficiency.
Multiple congenital coagulopathies co-expressed with Von Willebrand's disease: the experience of Hemophilia Region III Treatment Centers over 25 years and review of the literature.
Novel missense mutations in two patients with factor XI deficiency (Val271Leu and Tyr351Ser) and one patient with combined factor XI and factor IX deficiency (Phe349Val).
The use of epsilon-aminocaproic acid for the management of hemophilia in dental and oral surgery patients.
[Review of patients studied for coagulopathy in a Hematology/Oncology unit].
coagulation factor viia deficiency
Activated factor IX-antithrombin III complexes in human blood: quantification by an enzyme-linked differential antibody immunoassay and determination of the in vivo half-life.
An investigation of the spectrum of common and rare inherited coagulation disorders in North-Eastern Iran.
Changes in haemostasis and thrombosis associated with thyroid disease: Presentation of 2 cases.
Clinical and laboratory features of 178 children with recurrent epistaxis.
Congenital factor XI and factor VII deficiencies assure an apparent opposite protection against arterial or venous thrombosis: An intriguing observation.
Descriptive epidemiology of hemophilia and other coagulation disorders in mansoura, egypt: retrospective analysis.
Factor IX is activated in vivo by the tissue factor mechanism.
Low endoscopy bleeding risk in patients with congenital bleeding disorders.
Menorrhagia and reproductive health in rare bleeding disorders: a study from the Indian subcontinent.
Multiple congenital coagulopathies co-expressed with Von Willebrand's disease: the experience of Hemophilia Region III Treatment Centers over 25 years and review of the literature.
Obstetric analgesia and anaesthesia in women with inherited bleeding disorders.
Treatment of factor XI inhibitor using recombinant activated factor VIIa.
Unprovoked Pulmonary Embolism in Factor VII Deficiency.
[Inherited bleeding disorders common in Jews].
coagulation factor xa deficiency
An investigation of the spectrum of common and rare inherited coagulation disorders in North-Eastern Iran.
Autosomal recessive inherited bleeding disorders in Pakistan: a cross-sectional study from selected regions.
Menorrhagia and reproductive health in rare bleeding disorders: a study from the Indian subcontinent.
coagulation factor xia deficiency
2017 Scientific Sessions Sol Sherry Distinguished Lecture in Thrombosis: Factor XI as a Target for New Anticoagulants.
A 14-bp deletion (codon 554 del AAGgtaacagagtg) at exon 14/intron N junction of the coagulation factor XI gene disrupts splicing and causes severe factor XI deficiency.
A case of a severe factor XI deficiency in a Chinese woman with heavy menorrhagia.
A case of a severe factor XI deficiency in patient undergoing hemodialysis without the use of heparin.
A case of chronic myelomonocytic leukaemia and factor XI deficiency with a circulating anticoagulant.
A case of factor XI deficiency caused by compound heterozygous F11 gene mutation.
A case of factor XI deficiency in a patient undergoing an oesophagogastrectomy.
A Case Report on an Extremely Rare Disease: Factor XI Deficiency.
A classification system for cross-reactive material-negative factor XI deficiency.
A common ancestral mutation (C128X) occurring in 11 non-Jewish families from the UK with factor XI deficiency.
A comparison of murine and human factor XI.
A factor XI deficiency associated with a nonsense mutation (Trp501stop) in the catalytic domain.
A molecular genetic study of factor XI deficiency.
A murine model of factor XI deficiency.
A Novel Assay for Determining Bleeding Risk in Factor XI Deficiency.
A novel c.290G>A mutation in the Factor 11 gene in a Dutch Caucasian family with a Factor XI deficiency.
A novel congenital haemostatic defect: combined factor VII and factor XI deficiency.
A novel F11 mutation in a Chinese paediatric patient with severe factor XI deficiency.
A novel factor XI gene mutation associated with mild factor XI deficiency in a symptomatic patient.
A novel factor XI missense mutation (Val371Ile) in the activation loop is responsible for a case of mild type II factor XI deficiency.
A novel heterozygous missense mutation (His127Arg) in a family with inherited cross-reacting material positive factor XI deficiency.
A novel missense mutation Asp506Gly in Exon 13 of the F11 gene in an asymptomatic Korean woman with mild factor XI deficiency.
A novel mutation (Gln433Glu) in exon 12 combined with the G insertion in exon 13 causes severe factor XI deficiency in Japanese patients.
A novel mutation (Leu60Pro) in a Chinese pedigree with hereditary factor XI deficiency.
A novel mutation (Tyr503Cys) in a severe factor XI deficiency.
A novel mutation that leads to a congenital factor XI deficiency in a Japanese family.
A novel type of factor XI deficiency showing compound genetic abnormalities: a nonsense mutation and an impaired transcription.
A Review of Selected Genes with Known Effects on Performance and Health of Cattle.
A Sardinian Family with Factor XI Deficiency.
A simple and accurate microplate assay for the determination of factor XI in plasma.
A successful case of laparoscopic colorectal cancer resection in an elderly patient with factor XI deficiency.
A surgical case of cerebral hemorrhage in a patient with factor XI deficiency.
A type II mutation (Glu117stop), induction of allele-specific mRNA degradation and factor XI deficiency.
Abnormal plasma clot formation and fibrinolysis reveal bleeding tendency in patients with partial factor XI deficiency.
Abnormal plasma clot structure and stability distinguish bleeding risk in patients with severe factor XI deficiency.
Abnormal vaginal bleeding in adolescence as the presenting symptom of a bleeding diathesis.
Acquired agranulocytosis and factor XI deficiency in association with thymoma.
Acquired antibody to factor XI in a patient with congenital factor XI deficiency.
Acquired factor XI deficiency and therapeutic plasma exchange.
Acquired Factor XI Deficiency during SARS-CoV-2 Infection: Not Only Thrombosis.
Acquired factor XI deficiency in a child with membranoproliferative glomerulonephritis.
Acquired factor XI deficiency in systemic lupus erythematosus.
Acquired Factor XI Deficiency with Lupus Anticoagulant in a Pregnant Woman Diagnosed by the Eruptions and Pain in Fingers.
Acquired Factor XI Deficiency: A Rare Complication After Liver Transplantation.
Acquired factor XI inhibitors in two patients with hereditary factor XI deficiency.
Activated factor IX-antithrombin III complexes in human blood: quantification by an enzyme-linked differential antibody immunoassay and determination of the in vivo half-life.
Activation of factor IX by the reaction product of tissue factor and factor VII: additional pathway for initiating blood coagulation.
Activation of factor VII during alimentary lipemia occurs in healthy adults and patients with congenital factor XII or factor XI deficiency, but not in patients with factor IX deficiency.
Activation of the coagulation cascade after infusion of a factor XI concentrate in congenitally deficient patients.
Advances and dilemmas in factor XI.
Age estimate of the N370S mutation causing Gaucher disease in Ashkenazi Jews and European populations: A reappraisal of haplotype data.
Age estimates of two common mutations causing factor XI deficiency: recent genetic drift is not necessary for elevated disease incidence among Ashkenazi Jews.
Alpha 1 antitrypsin deficiency and plasma thromboplastin antecedent deficiency--a new association?
An Alu-mediated 31.5-kb deletion as the cause of factor XI deficiency in 2 unrelated patients.
An illustrative case and a review on the dosing of recombinant factor VIIa in congenital factor XI deficiency.
An insertion mutation of the bovine Fii gene is responsible for factor XI deficiency in Japanese black cattle.
An investigation of the spectrum of common and rare inherited coagulation disorders in North-Eastern Iran.
An unusual cause for bleeding in Ireland: factor XI deficiency.
Anaesthesia in a parturient with Noonan's syndrome.
Anaesthesia Management of a Patient with Factor XI Deficiency.
Anaesthetic management of a parturient with severe congenital factor XI deficiency undergoing caesarean section for triplet pregnancy.
Analysis of the structural effects of four novel and a previously known mutations causing factor XI deficiency.
Anesthetic experience of a patient with hereditary factor XI deficiency (Hemophilia C) : A case report.
Anesthetic management of a patient with factor XI deficiency and factor XI inhibitor undergoing a cesarean section.
Anesthetic management using peripheral nerve block in patients with factor XI deficiency: a case report.
Anesthetic strategy for cesarean section in a patient with factor XI deficiency. Case report.
Anticoagulation during CABG in factor XI deficiency, a case report.
Aortic valve replacement in an elderly patient with factor XI deficiency.
Arterial and venous thrombosis in rare congenital bleeding disorders: a critical review.
Assessment of two contact activation reagents for the diagnosis of congenital factor XI deficiency.
Autosomal recessive inherited bleeding disorders in Pakistan: a cross-sectional study from selected regions.
Biological determinants of bleeding in patients with heterozygous factor XI deficiency.
Bleeding and thrombosis in a patient with secondary antiphospholipid syndrome.
Bleeding predictors in factor-XI-deficient patients.
Bleeding problems in factor XI deficient women.
Blood coagulation in hemophilia A and hemophilia C.
Bovine factor XI deficiency: relationships between heterozygotes in Canada and Britain.
Cardiac surgery in patients with Hemophilia:is it safe?
Cardiovascular surgery in patients with congenital plasma coagulopathies.
Carrier rate of Factor XI deficiency in stunted Japanese black cattle.
Cataract Extraction Without Prophylactic Treatment in Patients With Severe Factor XI Deficiency.
Cerebellar haemorrhage, factor XI deficiency and concomitant risk factors.
Cerebellar hemorrhage due to factor XI deficiency.
Challenges of antithrombotic therapy in the management of cardiovascular disease in patients with inherited bleeding disorders: A single-centre experience.
Changes in haemostasis and thrombosis associated with thyroid disease: Presentation of 2 cases.
Characterisation of five factor XI mutations.
Characterization of combined factor VII and factor XI deficiencies.
Characterization of hereditary factor XI deficiency in Taiwanese patients: identification of three novel and two common mutations.
Characterization of seven novel mutations causing factor XI deficiency.
Clinical and laboratory features of 178 children with recurrent epistaxis.
Clinical and laboratory studies of plasma thromboplastin antecedent deficiency (PTA).
Clinical and molecular epidemiology of factor XI deficiency in India.
Clinical experience of factor XI deficiency: the role of fresh frozen plasma and factor XI concentrate.
Clinical manifestations and mutation spectrum of 57 subjects with congenital factor XI deficiency in China.
Clinical usefulness of desmopressin for prevention of surgical bleeding in patients with symptomatic heterozygous factor XI deficiency.
Co-existence of Bernard Soulier syndrome and factor XI deficiency in a family: a unified pathology?
Coagulation factor XI deficiency in Holstein cattle: expression and distribution of factor XI activity.
Coagulation Factor XI deficiency in Holstein cattle: testing program update.
Coagulation factor XI gene analysis in three factor XI deficient Austrian patients.
Coagulation factor XI: a database of mutations and polymorphisms associated with factor XI deficiency.
Coexistence of Prader-Willi syndrome, congenital ectropion uveae with glaucoma, and factor XI deficiency.
Combined Congenital Hypodysfibrinogemia and Factor XI Deficiency in a Chinese Family.
Combined deficiencies of Factor VIII (AHF) and Factor XI (PTA).
Combined dys-form of homozygous factor XI deficiency and heterozygous factor XII deficiency.
Combined factor VIII and factor XI congenital deficiency: a case report.
Combined factor VIII/factor XI deficiency may cause intra-familial clinical variability in haemophilia A among Ashkenazi Jews.
Combined high molecular weight Kininogen and factor XI deficiency.
Combined severe factor XI deficiency and von Willebrand's disease.
Commentary on Acquired Factor XI Deficiency during SARS-CoV-2 Infection: Not Only Thrombosis.
Comments on 'Management of parturients with Factor XI deficiency - 10 year case series and review of the literature'.
Comparison of bleeding tendency, factor XI coagulant activity, and factor XI antigen in 25 factor XI-deficient kindreds.
Complications of severe bleeding in a patient with undiagnosed Factor XI deficiency.
Compound heterozygosity for two novel mutations in a severe factor XI deficiency.
Comprehensive arrayed primer extension array for the detection of 59 sequence variants in 15 conditions prevalent among the (Ashkenazi) Jewish population.
Congenital bleeding disorders. Rational treatment options.
Congenital factor XI deficiency caused by a novel F11 missense variant: a case report.
Congenital factor XI deficiency in a domestic shorthair cat.
Congenital factor XI deficiency, complete genotype and phenotype of two Iranian families.
Congenital Factor XI Deficiency: An Update.
Congenital hemorrhagic disorders in Jordan.
Conversion Total Hip Arthroplasty Following Failed Hip Fracture Fixation in a Patient with Factor XI Deficiency: A Case Report.
Coronary artery bypass in hereditary factor XI deficiency.
Coronary artery stenting in a patient with factor XI deficiency.
Correction of facial deformities in patients with mild bleeding disorders: a report of three cases.
Correction of factor XI deficiency by liver transplantation.
Cys482Trp missense mutation in the coagulation factor XI gene (F11) in a Korean patient with factor XI deficiency.
Definition of the bleeding tendency in factor XI-deficient kindreds--a clinical and laboratory study.
Definition of the population at risk of bleeding due to factor XI deficiency in Ashkenazic Jews and the value of activated partial thromboplastin time in its detection.
Delayed hemorrhage after cervical conization unmasking severe factor XI deficiency.
Delayed intra-abdominal bleeding following hysterectomy successfully managed with angiographic embolization in a patient with factor XI deficiency.
Demonstration of a circulating anticoagulant in plasma thromboplastin antecedent deficiency.
Dental surgery in patients with severe factor XI deficiency without plasma replacement.
Descriptive epidemiology of hemophilia and other coagulation disorders in mansoura, egypt: retrospective analysis.
Diagnosis of Factor XI deficiency following congenital cataract extraction.
Diagnostic difficulties of factor XI deficiencies: interferences' assay or real deficit?
DNA extraction from bovine mummified fetuses and detection of factor XI gene deficiency in the mummies.
Dominant factor XI deficiency caused by mutations in the factor XI catalytic domain.
Effects of factor IX or factor XI deficiency on ferric chloride-induced carotid artery occlusion in mice.
Effects of factor XI deficiency on ferric chloride-induced vena cava thrombosis in mice.
Efficacy of irradiation and external hyperthermia in locally advanced, hormone-refractory or radiation recurrent prostate cancer: a preliminary report.
Eighteen unrelated patients with factor XI deficiency, four novel mutations and a 100% detection rate by denaturing high-performance liquid chromatography.
Epidural/spinal anesthesia during delivery in women with factor XI deficiency, a single center experience.
Evaluation of bedside prothrombin time and activated partial thromboplastin time measurement by coagulation analyzer CoaguCheck Plus in various clinical settings.
Evaluation of the use of global haemostasis assays to monitor treatment in factor XI deficiency.
Exploring the global landscape of genetic variation in coagulation factor XI deficiency.
Factor IX is activated in vivo by the tissue factor mechanism.
Factor XI (PTA) deficiency in an English-American kindred.
Factor XI activity and factor XI antigen in homozygous and heterozygous factor XI deficiency.
Factor XI and factor XII as targets for new anticoagulants.
Factor XI as a Target for New Anticoagulants.
Factor XI assay results in the CAP survey (1981).
Factor XI deficiency (PTA deficiency): a case study.
Factor XI deficiency acquired by liver transplantation.
Factor XI Deficiency Alters the Cytokine Response and Activation of Contact Proteases during Polymicrobial Sepsis in Mice.
Factor XI deficiency and a platelet defect.
Factor XI deficiency and aortic valve replacement: Perioperative management.
Factor XI deficiency and hemostasis.
Factor XI deficiency and its management.
Factor XI deficiency and its management: Meeting at the Royal Free Hospital, London, 11 December 1995.
Factor XI deficiency and obstetrical anesthesia.
Factor XI deficiency and orthognathic surgery: a case report on anesthesia management.
Factor XI Deficiency and Pregnancy: Abnormal Lab Values or Significant Risk?
Factor XI deficiency database: an interactive web database of mutations, phenotypes, and structural analysis tools.
Factor XI deficiency diagnosed following use of adalimumab.
Factor XI deficiency disclosed following haemorrhage related to a dental extraction. Brief review and case report.
Factor XI deficiency enhances the pulmonary allergic response to house dust mite in mice independent of factor XII.
Factor XI deficiency in a Bedouin family.
Factor XI deficiency in a geriatric population.
Factor XI Deficiency in a Patient with Cervical Spondylotic Myelopathy.
Factor XI deficiency in an Arab Moslem family in Israel.
Factor XI deficiency in an Ashkenazi Jewish child, causing severe postoperative hemorrhage.
Factor XI deficiency in animal models.
Factor XI deficiency in Ashkenazi Jews in Israel.
Factor XI Deficiency in Canadian Holsteins.
Factor XI deficiency in French Basques is caused predominantly by an ancestral Cys38Arg mutation in the factor XI gene.
Factor XI deficiency in humans.
Factor XI deficiency in Iranians: its clinical manifestations in comparison with those of classic hemophilia.
Factor XI deficiency in Kerry Blue Terriers.
Factor XI deficiency in Southern Iran: identification of a novel missense mutation.
Factor XI deficiency in surgical patients.
Factor XI deficiency in the French Basque Country.
Factor XI deficiency in women.
Factor XI deficiency is associated with lower risk for cardiovascular and venous thromboembolism events.
Factor XI deficiency is not associated with an increased risk of pneumonia and pneumonia-related mortality.
Factor XI deficiency presenting as hemarthrosis during pregnancy.
Factor XI deficiency presenting in pregnancy: diagnosis and management.
Factor XI Deficiency Protects Against Atherogenesis in Apolipoprotein E/Factor XI Double Knockout Mice.
Factor XI deficiency resulting in severe postoperative hemorrhage after odontectomy.
Factor XI deficiency with a novel homozygous mutation Trp599Arg near the C-terminal region.
Factor XI deficiency, juvenile rheumatoid arthritis and systemic lupus erythematosus. Report of the first case.
Factor XI deficiency--resolving the enigma?
Factor XI deficiency-related spontaneous primary intraventricular hemorrhage.
Factor XI deficiency.
Factor XI Deficiency.
Factor XI deficiency: a description of 34 cases and literature review.
Factor XI deficiency: a review.
Factor XI deficiency: detection and management during urological surgery.
Factor XI deficiency: genetic and clinical studies of a single kindred.
Factor XI deficiency: identification of six novel missense mutations (P23L, P69T, C92G, E243D, W497C and E547K).
Factor XI deficiency: implications for management of patients undergoing aesthetic surgery.
Factor XI deficiency: incidental diagnosis post coronary artery bypass graft.
Factor XI deficiency: literature review and case presentation.
Factor XI Deficiency: Review and Management in Pregnant Women.
Factor XI Deficiency: The Key Is Individualization.
Factor XI deficiency: two novel mutations in asymptomatic Italian patients.
Factor XI gene analysis in thrombophilia and factor XI deficiency.
Factor XI kinetics after plasma exchange in severe factor XI deficiency.
Factor XI mutation in a Holstein cow with repeat breeding in Japan.
Factor XI replacement for inherited factor XI deficiency in routine clinical practice: results of the HEMOLEVEN prospective 3-year postmarketing study.
Factor XI-related thrombosis and the role of concentrate treatment in factor XI deficiency.
Factor XI: a review of its biochemistry and deficiency.
Factor XII deficiency acquired by orthotopic liver transplantation: case report and review of the literature.
Failure of Routine Coagulation Screening Tests to Detect Heterozygous State of Bovine Factor XI Deficiency.
Failure to detect variant (CRM+) plasma thromboplastin antecedent (factor XI) molecules in hereditary plasma thromboplastin antecedent deficiency: a study of 125 patients of several ethnic backgrounds.
Feedback activation of factor XI by thrombin in plasma results in additional formation of thrombin that protects fibrin clots from fibrinolysis.
Fetal bilateral subdural haemorrhages. Prenatal diagnosis and spontaneous resolution by time of delivery.
Fibrin formation, fibrinopeptide A release, and platelet thrombus dimensions on subendothelium exposed to flowing native blood: greater in factor XII and XI than in factor VIII and IX deficiency.
First case of delayed traumatic intracerebral hemorrhage in a patient with undiagnosed factor XI deficiency: diagnosis and management review.
First diagnosis of factor XI deficiency in a patient with subarachnoid haemorrhage.
Four novel FXI gene mutations in three factor XI- deficient patients.
Fresh frozen plasma in the pediatric age group and in congenital coagulation factor deficiency.
Functions of AAV-CMV-F.IX And AAV-EF1alpha-F.IX in gene therapy for hemophilia B.
Gene variants in four pedigrees with hereditary coagulation factor XI deficiency and one novel mutation identification.
Genetic analysis of a pedigree with combined factor XII and factor XI deficiency.
Genetic analysis of a pedigree with hereditary coagulation factor XI deficiency.
Genetic Description of Factor XI Deficiency in Holstein Semen in Western Japan.
Global coagulation tests to assess the value of the presurgical treatment in a patient with congenital factor XI deficiency and inhibitor.
Gynaecological and obstetrical bleeding in Caucasian women with congenital factor XI deficiency: Results from a twenty-year, retrospective, observational study.
Gynaecological and obstetrical bleeding in women with factor XI deficiency - a systematic review.
Gynaecological and obstetrical bleeding in women with factor XI deficiency - a systematic review: response to rebuttal.
Hemarthrosis revealing congenital factor XI deficiency.
Hematological findings in Noonan syndrome.
Hemophilia C: A Case Report With Updates on Diagnosis and Management of a Rare Bleeding Disorder.
Hemophilic arthropathy of the temporomandibular joint: review of the literature, a case report, and discussion.
Hemorrhage in a cat caused by inhibition of factor XI (plasma thromboplastin antecedent).
Hereditary factor XI deficiency.
Heterozygous factor XI deficiency associated with three novel mutations.
High incidence of factor XI deficiency in Gaucher's disease.
High prevalence of acquired von Willebrand's syndrome in patients with thyroid diseases undergoing thyroid surgery.
Homozygosity for a Thr575Met missense mutation in the catalytic domain associated with factor XI deficiency.
Hysterectomy in a woman with factor XI deficiency.
Identification of a mutation associated with factor XI deficiency in Holstein cattle.
Identification of a novel F11 missense mutation (Ile463Ser) in a family with congenital factor XI deficiency.
Identification of a novel factor XI gene mutational event in a Dutch Caucasian family with inherited factor XI deficiency.
Identification of carriers of the mutation causing coagulation factor XI deficiency in Polish Holstein-Friesian cattle.
Identification of factor XI deficiency in Holstein cattle in Turkey.
Identification of factor XI deficiency in Holstein-Friesian cattle in Britain.
Identification of five novel mutations in the factor XI gene (F11) of patients with factor XI deficiency.
Identification of mutations and polymorphisms in the factor XI genes of an African American family by dideoxyfingerprinting.
Identification of two novel mutations in non-Jewish factor XI deficiency.
In vitro evaluation of factor IX as novel treatment for factor XI deficiency.
Increased time for homeostasis in hemodialysis. Factor XI deficiency (hemophilia C): Report of a case.
Induction of an inhibitor antibody to factor XI in a patient with severe inherited factor XI deficiency by Rh immune globulin.
Inheritance and bleeding in factor XI deficiency.
Inherited bleeding disorders.
Inherited factor XI deficiency confers no protection against acute myocardial infarction.
Inherited factor XI deficiency: a concise review.
Inhibitors to Factor XI in patients with severe Factor XI deficiency.
Intraneural hematoma after nerve stimulation-guided femoral block in a patient with factor XI deficiency: case report.
Is resistance futile? The role of activated thrombin-activatable fibrinolysis inhibitor resistance in bleeding in factor XI deficiency.
Is the assessment of von Willebrand disease prevalence an achievable challenge? The example of the French Basque Country where blood group O and factor XI deficiency are highly prevalent.
Is there a 'Basque' profile regarding autosomal recessive deficiencies of coagulation factors?
Late retrobulbar hemorrhage and blindness following malar fracture complicated by factor XI deficiency.
Liver transplantation for factor XI deficiency: cure before diagnosis.
Low endoscopy bleeding risk in patients with congenital bleeding disorders.
Low factor VIII levels are a risk factor for bleeding in patients with factor XI deficiency.
Lower doses of rFVIIa therapy are safe and effective for surgical interventions in patients with severe FXI deficiency and inhibitors.
Malignant fibrous histiocytoma of the heart complicated by factor XI deficiency in a Jehovah's Witness patient.
Management of an orthognathic surgery patient with factor XI deficiency: review and case report.
Management of factor XI deficiency in coronary artery bypass graft surgery by plasmapheresis and exchange transfusion.
Management of factor XI deficiency in gynecologic and obstetric patients.
Management of factor XI deficiency in oncological liver and colorectal surgery by therapeutic plasma exchange: A case report.
Management of factor XI inhibitor for cardiac intervention: successful treatment with immunosuppressive therapy and plasma exchange.
Management of gynecologic surgery in the patient with factor XI deficiency: a review of the literature.
Management of menorrhagia in women with inherited bleeding disorders: general principles and use of desmopressin.
Management of severe factor XI deficiency in cardiac surgery: A case report and review of the literature.
Management of Severe Factor XI Deficiency with Factor XI Concentrate to Facilitate Prolonged Use of a Thoracic Epidural Catheter.
Management of the delivery in pregnant women with severe factor XI deficiency.
Menorrhagia and reproductive health in rare bleeding disorders: a study from the Indian subcontinent.
Menorrhagia from a haematologist's point of view. Part II: management.
Molecular analysis in 12 factor XI deficiency patients from China: Identification of three novel splicing mutations.
Molecular Analysis in Factor XI Deficiency.
Molecular analysis of severe factor XI deficiency in three Italian patients.
Molecular basis and bleeding manifestations of factor XI deficiency in 11 Turkish families.
Molecular basis of severe factor XI deficiency in seven families from the west of France. Seven novel mutations, including an ancient Q88X mutation.
Molecular characterization of two novel mutations causing factor XI deficiency: A splicing defect and a missense mutation responsible for a CRM+ defect.
Molecular genetic analysis of factor XI deficiency: identification of five novel gene alterations and the origin of type II mutation in Portuguese families.
Molecular genetic analysis of severe coagulation factor XI deficiency in six Italian patients.
Molecular genetic analysis of the F11 gene in 14 Turkish patients with factor XI deficiency: identification of novel and recurrent mutations and their inheritance within families.
Molecular genetics aspects of factor XI deficiency and Glanzmann thrombasthenia.
Molecular investigation of 41 patients affected by coagulation factor XI deficiency.
Monitoring low dose recombinant factor VIIa therapy in patients with severe factor XI deficiency undergoing surgery.
More information on patients with factor XI deficiency.
Multiple congenital coagulopathies co-expressed with Von Willebrand's disease: the experience of Hemophilia Region III Treatment Centers over 25 years and review of the literature.
Myocardial infarction in a patient with factor XI deficiency and a lupus anticoagulant.
Myositis ossificans traumatica. Association with hemophilia (factor XI deficiency) in a football player.
New observations on factor XI deficiency.
Noonan syndrome: partial factor XI deficiency.
Normal aPTT in children with mild factor XI deficiency.
Normal platelet adhesiveness and aggregation in congenital PTA or Hageman factor deficiency.
Novel identification of Factor XI deficiency in Indian Sahiwal (Bos indicus) cattle.
Novel missense mutations in two patients with factor XI deficiency (Val271Leu and Tyr351Ser) and one patient with combined factor XI and factor IX deficiency (Phe349Val).
Obstetric analgesia and anaesthesia in women with inherited bleeding disorders.
One of the two common mutations causing factor XI deficiency in Ashkenazi Jews (type II) is also prevalent in Iraqi Jews, who represent the ancient gene pool of Jews.
Ophthalmic surgery and plasma thromboplastin antecedent (factor XI) deficiency.
Optimal management of an aneurysmal subarachnoid hemorrhage in a patient with known factor XI deficiency: a case report.
Osocimab: A Novel Agent in Preventing Venous Thromboembolism.
Partial and severe factor XI deficiency in South Australia and the usefulness of factor XI mutation analysis for diagnosis.
Patients with severe factor XI deficiency have a reduced incidence of deep-vein thrombosis.
Pedigree analysis of factor XI deficiency in Japanese black cattle.
Percutaneous Coronary Intervention in a Patient with Congenital Factor XI Deficiency and Acquired Inhibitor.
Percutaneous coronary intervention in a patient with factor XI deficiency.
Peri- and Postpartum Management of Patients With Factor XI Deficiency.
Perioperative anesthetic management in a patient with factor XI deficiency undergoing coronary artery bypass graft surgery.
Perioperative management of a redo aortic root replacement in a patient with severe factor XI deficiency.
Perioperative management of factor XI deficiency in a patient undergoing hip arthroplasty.
Perioperative use of modified thrombelastography in factor XI deficiency: a helpful method to assess drug effects.
Peripartum anesthetic management of patients with Factor XI deficiency.
Peripheral retinal vascular lesions in a patient with Gaucher disease and factor XI deficiency. Case report.
Plasma replacement therapy during labor is not mandatory for women with severe factor XI deficiency.
Plasma thromboplastin antecedent deficiency and its association with pseudohemophilia. A report of 2 cases.
Plasma thromboplastin antecedent deficiency and subarachnoid hemorrhage.
Plasma thromboplastin antecedent deficiency.
Plasma thromboplastin antecedent deficiency. Report of a case and review of literature.
Platelet and coagulation studies in Ehlers-Danlos syndrome.
Platelet dysfunction in Noonan's syndrome. A case with a platelet cyclooxygenase-like deficiency and chronic idiopathic thrombocytopenic purpura.
Platelet functional defects in women with unexplained menorrhagia.
Polyphosphate is a cofactor for the activation of factor XI by thrombin.
Postoperative primary adrenal failure from bilateral hemorrhagic adrenal infarction associated with coagulation factor XI deficiency.
Postpartum bleeding in women with inherited bleeding disorders: a matched cohort study.
Postpartum haemorrhage in women with mild factor XI deficiency.
Potential role of recombinant factor VIIa as a hemostatic agent.
Practical guidelines for the clinical use of plasma.
Pregnancy in women with von Willebrand's disease or factor XI deficiency.
Pregnancy outcome in Factor XI deficiency: incidence of miscarriage, antenatal and postnatal haemorrhage in 33 women with Factor XI deficiency.
Preliminary findings of altered follicular activity in Holstein cows with coagulation factor XI deficiency.
Preoperative management of factor XI deficiency with therapeutic plasma exchange: A case report and literature review.
Preoperative screening for coagulopathy using prothrombin time and partial thromboplastin time in patients requiring primary cranial vault remodeling.
Prevalence, causes, and characterization of factor XI inhibitors in patients with inherited factor XI deficiency.
Probable factor XI deficiency in Bantu subjects.
Procainamide-induced circulating anticoagulants in a congenitally-deficient factor XI patient.
Production and therapeutic use of a factor XI concentrate from plasma.
Prolonged activated partial thromboplastin time in pregnancy: a brief report.
PROLONGED BLEEDING TIME IN A PATIENT WITH PLASMA THROMBOPLASTIN ANTECEDENT DEFICIENCY: OBSERVATIONS ON CORRECTION OF THE BLEEDING TIME BY PLATELET TRANSFUSION.
Prophylactic use of desmopressin in surgery of six patients with symptomatic heterozygous factor XI deficiency.
Prospective analysis of factor XI deficiencies in the Marseilles area identified four novel mutations among 12 consecutive unrelated families.
Prostatectomy in factor XI (plasma thromboplastin antecedent) deficiency.
Prostatectomy in factor XI deficiency.
Pulmonary embolism and fatal stroke in a patient with severe factor XI deficiency after bariatric surgery.
Pulmonary embolism with factor XI deficiency.
Pulmonary valvulotomy in Factor XI deficiency.
Rare inherited bleeding disorders secondary to coagulation factors in Jordan: a nine-year study.
Recombinant factor VIIa for the prophylaxis of perioperative hemorrhage in a patient with congenital factor XI deficiency undergoing brain tumor neurosurgery.
Recombinant factor VIIa to prevent surgical bleeding in factor XI deficiency.
Recurrent venous thromboembolic disease and factor XI concentrate in a patient with severe factor XI deficiency, chronic myelomonocytic leukaemia, factor V Leiden and heterozygous plasminogen deficiency.
Reduced fibrinolytic resistance in patients with factor XI deficiency. Evidence of a thrombin-independent impairment of the thrombin-activatable fibrinolysis inhibitor pathway.
Reduced incidence of ischemic stroke in patients with severe factor XI deficiency.
Response to Wiewel-Verschueren S et al.: gynaecological and obstetrical bleeding in women with factor XI deficiency - a systematic review.
Retrospective analysis of 1312 patients with haemophilia and related disorders in a single Chinese institute.
Revisiting the molecular epidemiology of factor XI deficiency: nine new mutations and an original large 4qTer deletion in western Brittany (France).
Screening for bovine leukocyte adhesion deficiency, deficiency of uridine monophosphate synthase, complex vertebral malformation, bovine citrullinaemia, and factor XI deficiency in Holstein cows reared in Turkey.
Screening for factor XI deficiency amongst pregnant women of Ashkenazi Jewish origin.
Sensitivity of three activated partial thromboplastin time reagents to coagulation factor deficiencies.
Severe Ankle Arthritis After Multiple Hemarthrosis Secondary to Factor XI Deficiency: A Case Report.
Severe factor XI deficiency caused by a Gly555 to Glu mutation (factor XI-Glu555): a cross-reactive material positive variant defective in factor IX activation.
Severe factor XI deficiency caused by compound heterozygosity for the type III mutation and a novel insertion in exon 9 (codons 324/325 +G).
Severe factor XI deficiency caused by compound heterozygosity.
Severe factor XI deficiency in a Korean woman with a novel missense mutation (Val498Met) and duplication G mutation in exon 13 of the F11 gene.
Severe factor XI deficiency in a Lebanese family: identification of a novel missense mutation (Trp501Cys) in the catalytic domain.
Severe factor XI deficiency in an Arab family associated with a novel mutation in exon 11.
Severe factor XI deficiency in the Abruzzo region of Italy is associated to different FXI gene mutations.
Severe intraabdominal bleeding after transvaginal oocyte retrieval for IVF-ET and coagulation factor XI deficiency: a case report.
Simulation of normal, carrier and affected controls for large-scale genotyping of cattle for factor XI deficiency.
Simultaneous genotyping of coagulation factor XI type II and type III mutations by multiplex real-time polymerase chain reaction to determine their prevalence in healthy and factor XI-deficient Italians.
Six point mutations that cause factor XI deficiency.
Spectrum of factor XI (F11) mutations in the UK population--116 index cases and 140 mutations.
Spinal Anaesthesia for Caesarean Delivery in a Parturient with Partial Factor XI Deficiency.
Spontaneous hematomyelia secondary to factor XI deficiency. Case report.
Spontaneous spinal epidural hematoma, Brown-Séquard syndrome, and factor XI deficiency.
Spontaneous thrombosis in a patient with factor XI deficiency homozygous for the p.Cys398Tyr mutation.
Sporadic incidence of factor XI deficiency in Holstein cattle
Stereotactic core breast biopsy of a minimal carcinoma complicated by a large hematoma: a management dilemma.
Structural interpretation of 42 mutations causing factor XI deficiency using homology modeling.
Studies on a circulating anticoagulant inhibiting factor XI in a patient with congenital deficiency and carcinoma of the prostate.
Successful childbirth by a patient with congenital factor XI deficiency and an acquired inhibitor.
Successful hemostatic management of major surgery for cervical spondylotic myelopathy in a patient with severe factor XI deficiency.
Successful hip arthroplasty in an adult male with severe factor XI deficiency using Hemoleven(®) , a factor XI concentrate.
Successful perioperative management in a patient with factor XI deficiency.
Successful perioperative management of factor XI deficiency with administration of fresh-frozen plasma in a subdural hematoma patient.
Successful Peritoneal Dialysis Catheter Placement in a New End-Stage Renal Disease Patient with Combined Antiphospholipid Syndrome and Factor XI Deficiency.
Successful resection of sigmoid colon cancer in a patient with factor XI deficiency.
Successful treatment of a lung cancer patient with factor XI deficiency.
Successful Treatment of a Patient with Colon Cancer with Congenital Coagulation Factor XI Deficiency.
Successful use of recombinant factor VIIa (NovoSeven) during cardiac surgery in a pediatric patient with congenital factor XI deficiency.
Successful use of recombinant factor VIIa in a patient with inhibitor secondary to severe factor XI deficiency.
Supernumerary nipples in children with hematologic disorders.
SURGICAL OUTCOMES AFTER MASSIVE SUBRETINAL HEMORRHAGE SECONDARY TO AGE-RELATED MACULAR DEGENERATION.
The activated partial thromboplastin time and factor XI deficiency.
The clinical importance of factor XI deficiency in an Ashkenazi Jewish patient.
The clinical management of factor XI deficiency in pregnant women.
The correction of a hemorrhagic diathesis in preparation for surgery; the correction of plasma thromboplastin antecedent deficiency.
The effect of combined factor XI deficiency with von Willebrand factor abnormalities on haemorrhagic diathesis.
The enigma of severe factor XI deficiency without hemmorrhagic symptoms. Distinction from Hageman factor and "Fletcher factor" deficiency; family study; and problems of diagnosis.
The factor of factor XI deficiency in thyroid neoplasia.
The impact of thrombin generation and rotation thromboelastometry on assessment of severity of factor XI deficiency.
The lipoprotein-associated coagulation inhibitor.
The Management of Factor XI Deficiency in Pregnancy.
The management of factor XI deficiency.
The molecular genetics of factor XI deficiency.
The obstetric experience of women with factor XI deficiency.
The possible role of platelets in bypassing the contact phase of blood coagulation.
The profibrinolytic effect of plasma thrombomodulin in factor XI deficiency and its implications in hemostasis.
The rare inherited coagulation disorders.
The relationship between factor XI coagulant and factor XI antigenic activity in cattle.
The role of recombinant factor VIIa for obstetric block in women with severe factor XI deficiency.
The role of rotational thromboelastometry in assessment of haemostasis during pregnancy in women with factor XI deficiency.
The safety of chronic antithrombotic therapy in patients with factor XI deficiency.
The spectrum of factor XI deficiency in Italy.
The susceptibility of plasma coagulation factor XI to nitration and peroxynitrite action.
The two common mutations causing factor XI deficiency in Jews stem from distinct founders: one of ancient Middle Eastern origin and another of more recent European origin.
The use of desmopressin in congenital factor XI deficiency: a systematic review.
The use of epsilon-aminocaproic acid for the management of hemophilia in dental and oral surgery patients.
The use of fresh blood to control severe haemorrhage associated with massive blood transfusion after cardiopulmonary bypass.
The use of levonorgestrel-releasing intrauterine system for treatment of menorrhagia in women with inherited bleeding disorders.
The use of recombinant factor VIIa (NovoSeven) in a patient with a factor XI deficiency and a circulating anticoagulant.
Therapeutic plasma exchange for perioperative management of patients with congenital factor XI deficiency.
Three Factor 11 Mutations Associated with Factor XI Deficiency in a Turkish Family.
Thrombin generation in patients with factor XI deficiency and clinical bleeding risk.
Thromboembolic phenomena in patients with hereditary factor XI deficiency.
Tissue Factor-Independent Coagulation Correlates with Clinical Phenotype in Factor XI Deficiency and Replacement Therapy.
Tissue-specific expression of functional platelet factor XI is independent of plasma factor XI expression.
Total hip arthroplasty via the direct anterior approach with Kerboull-type acetabular reinforcement device for an elderly female with factor XI deficiency.
Transfer of congenital factor XI deficiency from a donor to a recipient by liver transplantation.
Transfusion-induced specific anti-factor XI inhibitor in a patient with previously unrecognized factor XI deficiency.
Transmission of factor VII deficiency through liver transplantation.
Transurethral prostatectomy in severe factor XI deficiency without bleeding complications.
Traumatic hyphema and factor XI deficiency (hemophilia C).
Treatment of factor XI deficiency.
Treatment of factor XI inhibitor using recombinant activated factor VIIa.
Turning Up to Eleven: Factor XI Inhibitors as Novel Agents to Maximize Safety and Maintain Efficacy in Thromboembolic Disease.
Two common mutations causing factor XI deficiency in Ashkenazi Jews may point to a European origin.
Two factor XI mutations in a Chinese family with factor XI deficiency.
Type I mutation in the F11 gene is a third ancestral mutation which causes factor XI deficiency in Ashkenazi Jews.
Ultrasound-Guided Thrombin Injection for Iliopsoas Pseudoaneurysm.
Undiagnosed bleeding states and medical treatment.
Uneventful cesarean delivery with administration of factor XI concentrate in a patient with severe factor XI deficiency.
Uneventful long-term anticoagulation with fluindione in a patient with severe factor XI deficiency.
Unexpected bleeding after elective nasal surgery.
Unprovoked Pulmonary Embolism in Factor VII Deficiency.
Update on the physiology and pathology of factor IX activation by factor XIa.
Use of recombinant factor VIIa for hip replacement surgery in a patient with severe factor XI deficiency and drug-induced platelet defect.
Variable bleeding manifestations characterize different types of surgery in patients with severe factor XI deficiency enabling parsimonious use of replacement therapy.
Vascular anomaly associated with plasma thromboplastin antecedent deficiency.
When genetic and surname analyses meet historical sources: The C56R mutation associated with factor XI deficiency as a marker of human migration during the Spanish Reconquista.
When the bleeding won't stop: a case report on a patient with hemophilia.
Why factor XI deficiency is a clinical concern.
[A case of a serious clotting defect, without hemorrhagic diathesis, caused by plasma thromboplastin antecedent deficiency.]
[A case of lupoid hepatitis, factor XI deficiency and Hashimoto's disease with circulating anticoagulant]
[A family of congenital factor XI deficiency]
[A rare case of hemorrhagic diathesis caused by plasma thromboplastin antecedent deficiency.]
[A study on platelet Factor XI-like activity in a family with congenital Factor XI deficiency]
[A successful surgical case of atrial septal defect with congenital factor XI deficiency]
[An uncommon cause of hematemesis in children: factor XI deficiency].
[Analysis of a pedigree affected with hereditary coagulation factor XI deficiency due to compound heterozygous variants of F11 gene].
[Anesthesia and perioperative management for cesarean section in patient with factor XI deficiency: a case report].
[Antifibrinolytics as a treatment for severe factor XI deficiency in laryngeal surgery]
[Appropriate laboratory investigation in women with menorrhagia].
[BLOOD COAGULATION IN FACTOR XI DEFICIENCY.]
[Cataract surgery with congenital factor XI deficiency: a case report]
[Congenital deficiency of factor XI: diagnosis and therapy in surgical patients (author's transl)]
[Considerations on plasma thromboplastin antecedent deficiency in rheumatic fever in childhood]
[Epidural anesthesia in a patient with factor XI deficiency]
[Factor XI deficiency caused by a mutation of Gly400Val]
[Factor XI deficiency, a new way of substitution: human purified concentrates]
[Factor XI deficiency: do patients with hemorrhagic diathesis also have hemostasis defects?]
[Factor XI deficiency]
[Familial study of factor XI deficiency. Presurgical prophylactic treatment with desmopressin plus antifibrinolytics]
[FXI gene mutations in two pedigrees of congenital clotting factor XI deficiency]
[Hemophilia C, a deficiency of a contact phase protein which may involve a risk of hemorrhage]
[Hemophilic syndrome of plasma thromboplastin antecedent deficiency; physiopathological and therapeutic aspects.]
[Hemorrhagic disease caused by plasma thromboplastin antecedent deficiency; case report.]
[Hereditary hemorrhagic telangiectasia and congenital factor XI deficiency]
[Identification of compound heterozygous mutations p.Gly400Val and p.Arg532Ter of the F11 gene in a Chinese patient with hereditary factor XI deficiency].
[Identification of novel compound heterozygous variants in a pedigree affected with hereditary coagulation factor XI deficiency].
[Identification of two novel factor XI non-sense mutation Trp228stop and Trp383stop in a Chinese pedigree of congenital factor XI deficiency]
[Inherited bleeding disorders common in Jews].
[Investigation into a family with factor XI deficiency and Willebrand-Jürgens syndrome]
[Isolated increased aPTT with anamnestic hemorrhagic diathesis--severe FXI deficiency]
[Isolated prolongation of the PTT: 2-year retrospective study]
[Labour epidural analgesia for a parturient with a factor XI deficiency: an ill-considered challenge or a reasonable risk?].
[Labour epidural analgesia for a woman with a factor XI deficiency: an illconsidered risk?]
[Menorrhagia and inherited disorders of coagulation]
[Partial familial factor XI deficiency]
[Plasma thromboplastin antecedent deficiency anemia.]
[Polycythemia vera and factor XI deficiency]
[Postoperative haemorrhagia in a girl with congenital factor XI deficiency - successful treatment with desmopressin (DDAVP, Minirin(R))]
[Postoperative hemorrhage due to factor XI deficiency]
[Preoperative disclosing of factor XI deficiency]
[Preoperative monitoring of blood coagulation in urologic operations: diagnosis of familial factor XI deficiency within the scope of preoperative blood coagulation studies]
[Problems posed by factor XI deficiency for the anesthetist (resuscitor)]
[Prolonged activated partial thromboplastin time (aPTT): not always indicative of increased risk of bleeding]
[Retroplacental hematoma and factor XI deficiency]
[Review of patients studied for coagulopathy in a Hematology/Oncology unit].
[Surgical experience in factor XI deficiency]
[The inherited coagulation factor XI deficiency caused by intronic mutation IVS J-4delgttg]
[Thrombocyte dysfunction in children with albinism]
[Thrombocytopenic thrombocytopathy in a case of factor XI deficiency]
[Use of recombinant, activated Factor VII in the treatment and prevention of bleeding complications in two female patients suffering from congenital XI factor deficiency during orthopedic and traumatology intervention. Case reports]
[You make the diagnosis. Heterozygote factor XI deficiency]
coagulation factor xiia deficiency
Activation of factor VII during alimentary lipemia occurs in healthy adults and patients with congenital factor XII or factor XI deficiency, but not in patients with factor IX deficiency.
Combined dys-form of homozygous factor XI deficiency and heterozygous factor XII deficiency.
Factor XI activation in a revised model of blood coagulation.
Factor XI and factor XII as targets for new anticoagulants.
Fibrin formation, fibrinopeptide A release, and platelet thrombus dimensions on subendothelium exposed to flowing native blood: greater in factor XII and XI than in factor VIII and IX deficiency.
Normal platelet adhesiveness and aggregation in congenital PTA or Hageman factor deficiency.
Polyphosphate is a cofactor for the activation of factor XI by thrombin.
[Review of patients studied for coagulopathy in a Hematology/Oncology unit].
[Successes and failures of the activated partial thromboplastin time in the preoperative evaluation]
[Unsuspected prolonged activated partial thromboplastin time in emergency surgery. Diagnostic and therapeutic guide]
Colitis, Ulcerative
P492. Resolution of factor XI (FXI) deficiency in refractory Ulcerative Colitis (UC) after surgery: A case report.
Colonic Neoplasms
Successful Treatment of a Patient with Colon Cancer with Congenital Coagulation Factor XI Deficiency.
Colorectal Neoplasms
A successful case of laparoscopic colorectal cancer resection in an elderly patient with factor XI deficiency.
Prolyl endopeptidase activity is correlated with colorectal cancer prognosis.
Communicable Diseases
Comparison of in vitro function of neutrophils from cattle deficient in plasma factor XI activity and from normal animals.
Congenital Abnormalities
Correction of facial deformities in patients with mild bleeding disorders: a report of three cases.
Identification of factor XI deficiency in Holstein-Friesian cattle in Britain.
Congenital Disorders of Glycosylation
Thrombotic complications in patients with PMM2-CDG.
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Long-standing mild hypertransaminasaemia caused by congenital disorder of glycosylation (CDG) type IIx.
Thrombotic complications in patients with PMM2-CDG.
Coronary Artery Disease
Evaluation of factor XIa-alpha 1-antitrypsin in plasma, a contact phase-activated coagulation factor-inhibitor complex, in patients with coronary artery disease.
Factor XIa and tissue factor activity in patients with coronary artery disease.
Coronary Disease
Elevated levels of plasma prekallikrein, high molecular weight kininogen and factor XI in coronary heart disease.
Lack of association of plasma factor XI with incident stroke and coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) Study.
Relation of coagulation factor XI with incident coronary heart disease and stroke: the Cardiovascular Health Study.
Cough
Potent cough suppression by physiologically active substance in human plasma.
COVID-19
Acquired Factor XI Deficiency during SARS-CoV-2 Infection: Not Only Thrombosis.
Commentary on Acquired Factor XI Deficiency during SARS-CoV-2 Infection: Not Only Thrombosis.
Crohn Disease
Kallikrein-kinin system activation in Crohn's disease: differences in intestinal and systemic markers.
Cystic Fibrosis
Mendelian diseases among Roman Jews: implications for the origins of disease alleles.
Cystitis
Efficacy of irradiation and external hyperthermia in locally advanced, hormone-refractory or radiation recurrent prostate cancer: a preliminary report.
Dengue
Activation of coagulation factor XI, without detectable contact activation in dengue haemorrhagic fever.
Depression, Postpartum
Effects of pregnancy and delivery on serum prolyl endopeptidase (PEP) activity: alterations in serum PEP are related to increased anxiety in the early puerperium and to postpartum depression.
Diabetes Complications
Inhibitors of Factor XIa and Plasma Kallikrein May Treat Thromboembolic Disorders and Many Diabetes Complications.
Diabetes Mellitus
Contact phase of coagulation in diabetes mellitus after aspirin administration.
Diabetes Mellitus, Type 1
Decreased plasma kallikrein activity is associated with reduced kidney function in individuals with type 1 diabetes.
Diabetic Nephropathies
[Immunologic aspects of renal involvement in patients with type II diabetes mellitus]
Disseminated Intravascular Coagulation
Circulating factor XI antibody and disseminated intravascular coagulation.
Factor XI Deficiency Alters the Cytokine Response and Activation of Contact Proteases during Polymicrobial Sepsis in Mice.
Dwarfism
A Review of Selected Genes with Known Effects on Performance and Health of Cattle.
Therapeutic uses of microencapsulated genetically engineered cells.
Dysautonomia, Familial
Comprehensive arrayed primer extension array for the detection of 59 sequence variants in 15 conditions prevalent among the (Ashkenazi) Jewish population.
Dystonia Musculorum Deformans
Comprehensive arrayed primer extension array for the detection of 59 sequence variants in 15 conditions prevalent among the (Ashkenazi) Jewish population.
Ecchymosis
Co-existence of Bernard Soulier syndrome and factor XI deficiency in a family: a unified pathology?
Myositis ossificans traumatica. Association with hemophilia (factor XI deficiency) in a football player.
Ectropion
Coexistence of Prader-Willi syndrome, congenital ectropion uveae with glaucoma, and factor XI deficiency.
Embolic Stroke
Novel Drug Targets for Ischemic Stroke Identified Through Mendelian Randomization Analysis of the Blood Proteome.
Stroke Prevention in Atrial Fibrillation: Looking Forward.
Endotoxemia
Activation of clotting factor XI without detectable contact activation in experimental human endotoxemia.
Simultaneous targeting of CD14 and factor XIa by a fusion protein consisting of an anti-CD14 antibody and the modified second domain of bikunin improves survival in rabbit sepsis models.
Epistaxis
Anesthetic experience of a patient with hereditary factor XI deficiency (Hemophilia C) : A case report.
Factor V Deficiency
An investigation of the spectrum of common and rare inherited coagulation disorders in North-Eastern Iran.
Arterial and venous thrombosis in rare congenital bleeding disorders: a critical review.
Descriptive epidemiology of hemophilia and other coagulation disorders in mansoura, egypt: retrospective analysis.
Fresh frozen plasma in the pediatric age group and in congenital coagulation factor deficiency.
Platelet functional defects in women with unexplained menorrhagia.
Factor VII Deficiency
Activated factor IX-antithrombin III complexes in human blood: quantification by an enzyme-linked differential antibody immunoassay and determination of the in vivo half-life.
An investigation of the spectrum of common and rare inherited coagulation disorders in North-Eastern Iran.
Changes in haemostasis and thrombosis associated with thyroid disease: Presentation of 2 cases.
Clinical and laboratory features of 178 children with recurrent epistaxis.
Congenital factor XI and factor VII deficiencies assure an apparent opposite protection against arterial or venous thrombosis: An intriguing observation.
Descriptive epidemiology of hemophilia and other coagulation disorders in mansoura, egypt: retrospective analysis.
Factor IX is activated in vivo by the tissue factor mechanism.
Low endoscopy bleeding risk in patients with congenital bleeding disorders.
Menorrhagia and reproductive health in rare bleeding disorders: a study from the Indian subcontinent.
Multiple congenital coagulopathies co-expressed with Von Willebrand's disease: the experience of Hemophilia Region III Treatment Centers over 25 years and review of the literature.
Obstetric analgesia and anaesthesia in women with inherited bleeding disorders.
Treatment of factor XI inhibitor using recombinant activated factor VIIa.
Unprovoked Pulmonary Embolism in Factor VII Deficiency.
[Inherited bleeding disorders common in Jews].
Factor X Deficiency
An investigation of the spectrum of common and rare inherited coagulation disorders in North-Eastern Iran.
Autosomal recessive inherited bleeding disorders in Pakistan: a cross-sectional study from selected regions.
Menorrhagia and reproductive health in rare bleeding disorders: a study from the Indian subcontinent.
Factor XI Deficiency
2017 Scientific Sessions Sol Sherry Distinguished Lecture in Thrombosis: Factor XI as a Target for New Anticoagulants.
A 14-bp deletion (codon 554 del AAGgtaacagagtg) at exon 14/intron N junction of the coagulation factor XI gene disrupts splicing and causes severe factor XI deficiency.
A case of a severe factor XI deficiency in a Chinese woman with heavy menorrhagia.
A case of a severe factor XI deficiency in patient undergoing hemodialysis without the use of heparin.
A case of chronic myelomonocytic leukaemia and factor XI deficiency with a circulating anticoagulant.
A case of factor XI deficiency caused by compound heterozygous F11 gene mutation.
A case of factor XI deficiency in a patient undergoing an oesophagogastrectomy.
A Case Report on an Extremely Rare Disease: Factor XI Deficiency.
A classification system for cross-reactive material-negative factor XI deficiency.
A common ancestral mutation (C128X) occurring in 11 non-Jewish families from the UK with factor XI deficiency.
A comparison of murine and human factor XI.
A factor XI deficiency associated with a nonsense mutation (Trp501stop) in the catalytic domain.
A molecular genetic study of factor XI deficiency.
A murine model of factor XI deficiency.
A Novel Assay for Determining Bleeding Risk in Factor XI Deficiency.
A novel c.290G>A mutation in the Factor 11 gene in a Dutch Caucasian family with a Factor XI deficiency.
A novel congenital haemostatic defect: combined factor VII and factor XI deficiency.
A novel F11 mutation in a Chinese paediatric patient with severe factor XI deficiency.
A novel factor XI gene mutation associated with mild factor XI deficiency in a symptomatic patient.
A novel factor XI missense mutation (Val371Ile) in the activation loop is responsible for a case of mild type II factor XI deficiency.
A novel heterozygous missense mutation (His127Arg) in a family with inherited cross-reacting material positive factor XI deficiency.
A novel missense mutation Asp506Gly in Exon 13 of the F11 gene in an asymptomatic Korean woman with mild factor XI deficiency.
A novel mutation (Gln433Glu) in exon 12 combined with the G insertion in exon 13 causes severe factor XI deficiency in Japanese patients.
A novel mutation (Leu60Pro) in a Chinese pedigree with hereditary factor XI deficiency.
A novel mutation (Tyr503Cys) in a severe factor XI deficiency.
A novel mutation that leads to a congenital factor XI deficiency in a Japanese family.
A novel type of factor XI deficiency showing compound genetic abnormalities: a nonsense mutation and an impaired transcription.
A Review of Selected Genes with Known Effects on Performance and Health of Cattle.
A Sardinian Family with Factor XI Deficiency.
A simple and accurate microplate assay for the determination of factor XI in plasma.
A successful case of laparoscopic colorectal cancer resection in an elderly patient with factor XI deficiency.
A surgical case of cerebral hemorrhage in a patient with factor XI deficiency.
A type II mutation (Glu117stop), induction of allele-specific mRNA degradation and factor XI deficiency.
Abnormal plasma clot formation and fibrinolysis reveal bleeding tendency in patients with partial factor XI deficiency.
Abnormal plasma clot structure and stability distinguish bleeding risk in patients with severe factor XI deficiency.
Abnormal vaginal bleeding in adolescence as the presenting symptom of a bleeding diathesis.
Acquired agranulocytosis and factor XI deficiency in association with thymoma.
Acquired antibody to factor XI in a patient with congenital factor XI deficiency.
Acquired factor XI deficiency and therapeutic plasma exchange.
Acquired Factor XI Deficiency during SARS-CoV-2 Infection: Not Only Thrombosis.
Acquired factor XI deficiency in a child with membranoproliferative glomerulonephritis.
Acquired factor XI deficiency in systemic lupus erythematosus.
Acquired Factor XI Deficiency with Lupus Anticoagulant in a Pregnant Woman Diagnosed by the Eruptions and Pain in Fingers.
Acquired Factor XI Deficiency: A Rare Complication After Liver Transplantation.
Acquired factor XI inhibitors in two patients with hereditary factor XI deficiency.
Activated factor IX-antithrombin III complexes in human blood: quantification by an enzyme-linked differential antibody immunoassay and determination of the in vivo half-life.
Activation of factor IX by the reaction product of tissue factor and factor VII: additional pathway for initiating blood coagulation.
Activation of factor VII during alimentary lipemia occurs in healthy adults and patients with congenital factor XII or factor XI deficiency, but not in patients with factor IX deficiency.
Activation of the coagulation cascade after infusion of a factor XI concentrate in congenitally deficient patients.
Advances and dilemmas in factor XI.
Age estimate of the N370S mutation causing Gaucher disease in Ashkenazi Jews and European populations: A reappraisal of haplotype data.
Age estimates of two common mutations causing factor XI deficiency: recent genetic drift is not necessary for elevated disease incidence among Ashkenazi Jews.
Alpha 1 antitrypsin deficiency and plasma thromboplastin antecedent deficiency--a new association?
An Alu-mediated 31.5-kb deletion as the cause of factor XI deficiency in 2 unrelated patients.
An illustrative case and a review on the dosing of recombinant factor VIIa in congenital factor XI deficiency.
An insertion mutation of the bovine Fii gene is responsible for factor XI deficiency in Japanese black cattle.
An investigation of the spectrum of common and rare inherited coagulation disorders in North-Eastern Iran.
An unusual cause for bleeding in Ireland: factor XI deficiency.
Anaesthesia in a parturient with Noonan's syndrome.
Anaesthesia Management of a Patient with Factor XI Deficiency.
Anaesthetic management of a parturient with severe congenital factor XI deficiency undergoing caesarean section for triplet pregnancy.
Analysis of the structural effects of four novel and a previously known mutations causing factor XI deficiency.
Anesthetic experience of a patient with hereditary factor XI deficiency (Hemophilia C) : A case report.
Anesthetic management of a patient with factor XI deficiency and factor XI inhibitor undergoing a cesarean section.
Anesthetic management using peripheral nerve block in patients with factor XI deficiency: a case report.
Anesthetic strategy for cesarean section in a patient with factor XI deficiency. Case report.
Anticoagulation during CABG in factor XI deficiency, a case report.
Aortic valve replacement in an elderly patient with factor XI deficiency.
Arterial and venous thrombosis in rare congenital bleeding disorders: a critical review.
Assessment of two contact activation reagents for the diagnosis of congenital factor XI deficiency.
Autosomal recessive inherited bleeding disorders in Pakistan: a cross-sectional study from selected regions.
Biological determinants of bleeding in patients with heterozygous factor XI deficiency.
Bleeding and thrombosis in a patient with secondary antiphospholipid syndrome.
Bleeding predictors in factor-XI-deficient patients.
Bleeding problems in factor XI deficient women.
Blood coagulation in hemophilia A and hemophilia C.
Bovine factor XI deficiency: relationships between heterozygotes in Canada and Britain.
Cardiac surgery in patients with Hemophilia:is it safe?
Cardiovascular surgery in patients with congenital plasma coagulopathies.
Carrier rate of Factor XI deficiency in stunted Japanese black cattle.
Cataract Extraction Without Prophylactic Treatment in Patients With Severe Factor XI Deficiency.
Cerebellar haemorrhage, factor XI deficiency and concomitant risk factors.
Cerebellar hemorrhage due to factor XI deficiency.
Challenges of antithrombotic therapy in the management of cardiovascular disease in patients with inherited bleeding disorders: A single-centre experience.
Changes in haemostasis and thrombosis associated with thyroid disease: Presentation of 2 cases.
Characterisation of five factor XI mutations.
Characterization of combined factor VII and factor XI deficiencies.
Characterization of hereditary factor XI deficiency in Taiwanese patients: identification of three novel and two common mutations.
Characterization of seven novel mutations causing factor XI deficiency.
Clinical and laboratory features of 178 children with recurrent epistaxis.
Clinical and laboratory studies of plasma thromboplastin antecedent deficiency (PTA).
Clinical and molecular epidemiology of factor XI deficiency in India.
Clinical experience of factor XI deficiency: the role of fresh frozen plasma and factor XI concentrate.
Clinical manifestations and mutation spectrum of 57 subjects with congenital factor XI deficiency in China.
Clinical usefulness of desmopressin for prevention of surgical bleeding in patients with symptomatic heterozygous factor XI deficiency.
Co-existence of Bernard Soulier syndrome and factor XI deficiency in a family: a unified pathology?
Coagulation factor XI deficiency in Holstein cattle: expression and distribution of factor XI activity.
Coagulation Factor XI deficiency in Holstein cattle: testing program update.
Coagulation factor XI gene analysis in three factor XI deficient Austrian patients.
Coagulation factor XI: a database of mutations and polymorphisms associated with factor XI deficiency.
Coexistence of Prader-Willi syndrome, congenital ectropion uveae with glaucoma, and factor XI deficiency.
Combined Congenital Hypodysfibrinogemia and Factor XI Deficiency in a Chinese Family.
Combined deficiencies of Factor VIII (AHF) and Factor XI (PTA).
Combined dys-form of homozygous factor XI deficiency and heterozygous factor XII deficiency.
Combined factor VIII and factor XI congenital deficiency: a case report.
Combined factor VIII/factor XI deficiency may cause intra-familial clinical variability in haemophilia A among Ashkenazi Jews.
Combined high molecular weight Kininogen and factor XI deficiency.
Combined severe factor XI deficiency and von Willebrand's disease.
Commentary on Acquired Factor XI Deficiency during SARS-CoV-2 Infection: Not Only Thrombosis.
Comments on 'Management of parturients with Factor XI deficiency - 10 year case series and review of the literature'.
Comparison of bleeding tendency, factor XI coagulant activity, and factor XI antigen in 25 factor XI-deficient kindreds.
Complications of severe bleeding in a patient with undiagnosed Factor XI deficiency.
Compound heterozygosity for two novel mutations in a severe factor XI deficiency.
Comprehensive arrayed primer extension array for the detection of 59 sequence variants in 15 conditions prevalent among the (Ashkenazi) Jewish population.
Congenital bleeding disorders. Rational treatment options.
Congenital factor XI deficiency caused by a novel F11 missense variant: a case report.
Congenital factor XI deficiency in a domestic shorthair cat.
Congenital factor XI deficiency, complete genotype and phenotype of two Iranian families.
Congenital Factor XI Deficiency: An Update.
Congenital hemorrhagic disorders in Jordan.
Conversion Total Hip Arthroplasty Following Failed Hip Fracture Fixation in a Patient with Factor XI Deficiency: A Case Report.
Coronary artery bypass in hereditary factor XI deficiency.
Coronary artery stenting in a patient with factor XI deficiency.
Correction of facial deformities in patients with mild bleeding disorders: a report of three cases.
Correction of factor XI deficiency by liver transplantation.
Cys482Trp missense mutation in the coagulation factor XI gene (F11) in a Korean patient with factor XI deficiency.
Definition of the bleeding tendency in factor XI-deficient kindreds--a clinical and laboratory study.
Definition of the population at risk of bleeding due to factor XI deficiency in Ashkenazic Jews and the value of activated partial thromboplastin time in its detection.
Delayed hemorrhage after cervical conization unmasking severe factor XI deficiency.
Delayed intra-abdominal bleeding following hysterectomy successfully managed with angiographic embolization in a patient with factor XI deficiency.
Demonstration of a circulating anticoagulant in plasma thromboplastin antecedent deficiency.
Dental surgery in patients with severe factor XI deficiency without plasma replacement.
Descriptive epidemiology of hemophilia and other coagulation disorders in mansoura, egypt: retrospective analysis.
Diagnosis of Factor XI deficiency following congenital cataract extraction.
Diagnostic difficulties of factor XI deficiencies: interferences' assay or real deficit?
DNA extraction from bovine mummified fetuses and detection of factor XI gene deficiency in the mummies.
Dominant factor XI deficiency caused by mutations in the factor XI catalytic domain.
Effects of factor IX or factor XI deficiency on ferric chloride-induced carotid artery occlusion in mice.
Effects of factor XI deficiency on ferric chloride-induced vena cava thrombosis in mice.
Efficacy of irradiation and external hyperthermia in locally advanced, hormone-refractory or radiation recurrent prostate cancer: a preliminary report.
Eighteen unrelated patients with factor XI deficiency, four novel mutations and a 100% detection rate by denaturing high-performance liquid chromatography.
Epidural/spinal anesthesia during delivery in women with factor XI deficiency, a single center experience.
Evaluation of bedside prothrombin time and activated partial thromboplastin time measurement by coagulation analyzer CoaguCheck Plus in various clinical settings.
Evaluation of the use of global haemostasis assays to monitor treatment in factor XI deficiency.
Exploring the global landscape of genetic variation in coagulation factor XI deficiency.
Factor IX is activated in vivo by the tissue factor mechanism.
Factor XI (PTA) deficiency in an English-American kindred.
Factor XI activity and factor XI antigen in homozygous and heterozygous factor XI deficiency.
Factor XI and factor XII as targets for new anticoagulants.
Factor XI as a Target for New Anticoagulants.
Factor XI assay results in the CAP survey (1981).
Factor XI deficiency (PTA deficiency): a case study.
Factor XI deficiency acquired by liver transplantation.
Factor XI Deficiency Alters the Cytokine Response and Activation of Contact Proteases during Polymicrobial Sepsis in Mice.
Factor XI deficiency and a platelet defect.
Factor XI deficiency and aortic valve replacement: Perioperative management.
Factor XI deficiency and hemostasis.
Factor XI deficiency and its management.
Factor XI deficiency and its management: Meeting at the Royal Free Hospital, London, 11 December 1995.
Factor XI deficiency and obstetrical anesthesia.
Factor XI deficiency and orthognathic surgery: a case report on anesthesia management.
Factor XI Deficiency and Pregnancy: Abnormal Lab Values or Significant Risk?
Factor XI deficiency database: an interactive web database of mutations, phenotypes, and structural analysis tools.
Factor XI deficiency diagnosed following use of adalimumab.
Factor XI deficiency disclosed following haemorrhage related to a dental extraction. Brief review and case report.
Factor XI deficiency enhances the pulmonary allergic response to house dust mite in mice independent of factor XII.
Factor XI deficiency in a Bedouin family.
Factor XI deficiency in a geriatric population.
Factor XI Deficiency in a Patient with Cervical Spondylotic Myelopathy.
Factor XI deficiency in an Arab Moslem family in Israel.
Factor XI deficiency in an Ashkenazi Jewish child, causing severe postoperative hemorrhage.
Factor XI deficiency in animal models.
Factor XI deficiency in Ashkenazi Jews in Israel.
Factor XI Deficiency in Canadian Holsteins.
Factor XI deficiency in French Basques is caused predominantly by an ancestral Cys38Arg mutation in the factor XI gene.
Factor XI deficiency in humans.
Factor XI deficiency in Iranians: its clinical manifestations in comparison with those of classic hemophilia.
Factor XI deficiency in Kerry Blue Terriers.
Factor XI deficiency in Southern Iran: identification of a novel missense mutation.
Factor XI deficiency in surgical patients.
Factor XI deficiency in the French Basque Country.
Factor XI deficiency in women.
Factor XI deficiency is associated with lower risk for cardiovascular and venous thromboembolism events.
Factor XI deficiency is not associated with an increased risk of pneumonia and pneumonia-related mortality.
Factor XI deficiency presenting as hemarthrosis during pregnancy.
Factor XI deficiency presenting in pregnancy: diagnosis and management.
Factor XI Deficiency Protects Against Atherogenesis in Apolipoprotein E/Factor XI Double Knockout Mice.
Factor XI deficiency resulting in severe postoperative hemorrhage after odontectomy.
Factor XI deficiency with a novel homozygous mutation Trp599Arg near the C-terminal region.
Factor XI deficiency, juvenile rheumatoid arthritis and systemic lupus erythematosus. Report of the first case.
Factor XI deficiency--resolving the enigma?
Factor XI deficiency-related spontaneous primary intraventricular hemorrhage.
Factor XI deficiency.
Factor XI Deficiency.
Factor XI deficiency: a description of 34 cases and literature review.
Factor XI deficiency: a review.
Factor XI deficiency: detection and management during urological surgery.
Factor XI deficiency: genetic and clinical studies of a single kindred.
Factor XI deficiency: identification of six novel missense mutations (P23L, P69T, C92G, E243D, W497C and E547K).
Factor XI deficiency: implications for management of patients undergoing aesthetic surgery.
Factor XI deficiency: incidental diagnosis post coronary artery bypass graft.
Factor XI deficiency: literature review and case presentation.
Factor XI Deficiency: Review and Management in Pregnant Women.
Factor XI Deficiency: The Key Is Individualization.
Factor XI deficiency: two novel mutations in asymptomatic Italian patients.
Factor XI gene analysis in thrombophilia and factor XI deficiency.
Factor XI kinetics after plasma exchange in severe factor XI deficiency.
Factor XI mutation in a Holstein cow with repeat breeding in Japan.
Factor XI replacement for inherited factor XI deficiency in routine clinical practice: results of the HEMOLEVEN prospective 3-year postmarketing study.
Factor XI-related thrombosis and the role of concentrate treatment in factor XI deficiency.
Factor XI: a review of its biochemistry and deficiency.
Factor XII deficiency acquired by orthotopic liver transplantation: case report and review of the literature.
Failure of Routine Coagulation Screening Tests to Detect Heterozygous State of Bovine Factor XI Deficiency.
Failure to detect variant (CRM+) plasma thromboplastin antecedent (factor XI) molecules in hereditary plasma thromboplastin antecedent deficiency: a study of 125 patients of several ethnic backgrounds.
Feedback activation of factor XI by thrombin in plasma results in additional formation of thrombin that protects fibrin clots from fibrinolysis.
Fetal bilateral subdural haemorrhages. Prenatal diagnosis and spontaneous resolution by time of delivery.
Fibrin formation, fibrinopeptide A release, and platelet thrombus dimensions on subendothelium exposed to flowing native blood: greater in factor XII and XI than in factor VIII and IX deficiency.
First case of delayed traumatic intracerebral hemorrhage in a patient with undiagnosed factor XI deficiency: diagnosis and management review.
First diagnosis of factor XI deficiency in a patient with subarachnoid haemorrhage.
Four novel FXI gene mutations in three factor XI- deficient patients.
Fresh frozen plasma in the pediatric age group and in congenital coagulation factor deficiency.
Functions of AAV-CMV-F.IX And AAV-EF1alpha-F.IX in gene therapy for hemophilia B.
Gene variants in four pedigrees with hereditary coagulation factor XI deficiency and one novel mutation identification.
Genetic analysis of a pedigree with combined factor XII and factor XI deficiency.
Genetic analysis of a pedigree with hereditary coagulation factor XI deficiency.
Genetic Description of Factor XI Deficiency in Holstein Semen in Western Japan.
Global coagulation tests to assess the value of the presurgical treatment in a patient with congenital factor XI deficiency and inhibitor.
Gynaecological and obstetrical bleeding in Caucasian women with congenital factor XI deficiency: Results from a twenty-year, retrospective, observational study.
Gynaecological and obstetrical bleeding in women with factor XI deficiency - a systematic review.
Gynaecological and obstetrical bleeding in women with factor XI deficiency - a systematic review: response to rebuttal.
Hemarthrosis revealing congenital factor XI deficiency.
Hematological findings in Noonan syndrome.
Hemophilia C: A Case Report With Updates on Diagnosis and Management of a Rare Bleeding Disorder.
Hemophilic arthropathy of the temporomandibular joint: review of the literature, a case report, and discussion.
Hemorrhage in a cat caused by inhibition of factor XI (plasma thromboplastin antecedent).
Hereditary factor XI deficiency.
Heterozygous factor XI deficiency associated with three novel mutations.
High incidence of factor XI deficiency in Gaucher's disease.
High prevalence of acquired von Willebrand's syndrome in patients with thyroid diseases undergoing thyroid surgery.
Homozygosity for a Thr575Met missense mutation in the catalytic domain associated with factor XI deficiency.
Hysterectomy in a woman with factor XI deficiency.
Identification of a mutation associated with factor XI deficiency in Holstein cattle.
Identification of a novel F11 missense mutation (Ile463Ser) in a family with congenital factor XI deficiency.
Identification of a novel factor XI gene mutational event in a Dutch Caucasian family with inherited factor XI deficiency.
Identification of carriers of the mutation causing coagulation factor XI deficiency in Polish Holstein-Friesian cattle.
Identification of factor XI deficiency in Holstein cattle in Turkey.
Identification of factor XI deficiency in Holstein-Friesian cattle in Britain.
Identification of five novel mutations in the factor XI gene (F11) of patients with factor XI deficiency.
Identification of mutations and polymorphisms in the factor XI genes of an African American family by dideoxyfingerprinting.
Identification of two novel mutations in non-Jewish factor XI deficiency.
In vitro evaluation of factor IX as novel treatment for factor XI deficiency.
Increased time for homeostasis in hemodialysis. Factor XI deficiency (hemophilia C): Report of a case.
Induction of an inhibitor antibody to factor XI in a patient with severe inherited factor XI deficiency by Rh immune globulin.
Inheritance and bleeding in factor XI deficiency.
Inherited bleeding disorders.
Inherited factor XI deficiency confers no protection against acute myocardial infarction.
Inherited factor XI deficiency: a concise review.
Inhibitors to Factor XI in patients with severe Factor XI deficiency.
Intraneural hematoma after nerve stimulation-guided femoral block in a patient with factor XI deficiency: case report.
Is resistance futile? The role of activated thrombin-activatable fibrinolysis inhibitor resistance in bleeding in factor XI deficiency.
Is the assessment of von Willebrand disease prevalence an achievable challenge? The example of the French Basque Country where blood group O and factor XI deficiency are highly prevalent.
Is there a 'Basque' profile regarding autosomal recessive deficiencies of coagulation factors?
Late retrobulbar hemorrhage and blindness following malar fracture complicated by factor XI deficiency.
Liver transplantation for factor XI deficiency: cure before diagnosis.
Low endoscopy bleeding risk in patients with congenital bleeding disorders.
Low factor VIII levels are a risk factor for bleeding in patients with factor XI deficiency.
Lower doses of rFVIIa therapy are safe and effective for surgical interventions in patients with severe FXI deficiency and inhibitors.
Malignant fibrous histiocytoma of the heart complicated by factor XI deficiency in a Jehovah's Witness patient.
Management of an orthognathic surgery patient with factor XI deficiency: review and case report.
Management of factor XI deficiency in coronary artery bypass graft surgery by plasmapheresis and exchange transfusion.
Management of factor XI deficiency in gynecologic and obstetric patients.
Management of factor XI deficiency in oncological liver and colorectal surgery by therapeutic plasma exchange: A case report.
Management of factor XI inhibitor for cardiac intervention: successful treatment with immunosuppressive therapy and plasma exchange.
Management of gynecologic surgery in the patient with factor XI deficiency: a review of the literature.
Management of menorrhagia in women with inherited bleeding disorders: general principles and use of desmopressin.
Management of severe factor XI deficiency in cardiac surgery: A case report and review of the literature.
Management of Severe Factor XI Deficiency with Factor XI Concentrate to Facilitate Prolonged Use of a Thoracic Epidural Catheter.
Management of the delivery in pregnant women with severe factor XI deficiency.
Menorrhagia and reproductive health in rare bleeding disorders: a study from the Indian subcontinent.
Menorrhagia from a haematologist's point of view. Part II: management.
Molecular analysis in 12 factor XI deficiency patients from China: Identification of three novel splicing mutations.
Molecular Analysis in Factor XI Deficiency.
Molecular analysis of severe factor XI deficiency in three Italian patients.
Molecular basis and bleeding manifestations of factor XI deficiency in 11 Turkish families.
Molecular basis of severe factor XI deficiency in seven families from the west of France. Seven novel mutations, including an ancient Q88X mutation.
Molecular characterization of two novel mutations causing factor XI deficiency: A splicing defect and a missense mutation responsible for a CRM+ defect.
Molecular genetic analysis of factor XI deficiency: identification of five novel gene alterations and the origin of type II mutation in Portuguese families.
Molecular genetic analysis of severe coagulation factor XI deficiency in six Italian patients.
Molecular genetic analysis of the F11 gene in 14 Turkish patients with factor XI deficiency: identification of novel and recurrent mutations and their inheritance within families.
Molecular genetics aspects of factor XI deficiency and Glanzmann thrombasthenia.
Molecular investigation of 41 patients affected by coagulation factor XI deficiency.
Monitoring low dose recombinant factor VIIa therapy in patients with severe factor XI deficiency undergoing surgery.
More information on patients with factor XI deficiency.
Multiple congenital coagulopathies co-expressed with Von Willebrand's disease: the experience of Hemophilia Region III Treatment Centers over 25 years and review of the literature.
Myocardial infarction in a patient with factor XI deficiency and a lupus anticoagulant.
Myositis ossificans traumatica. Association with hemophilia (factor XI deficiency) in a football player.
New observations on factor XI deficiency.
Noonan syndrome: partial factor XI deficiency.
Normal aPTT in children with mild factor XI deficiency.
Normal platelet adhesiveness and aggregation in congenital PTA or Hageman factor deficiency.
Novel identification of Factor XI deficiency in Indian Sahiwal (Bos indicus) cattle.
Novel missense mutations in two patients with factor XI deficiency (Val271Leu and Tyr351Ser) and one patient with combined factor XI and factor IX deficiency (Phe349Val).
Obstetric analgesia and anaesthesia in women with inherited bleeding disorders.
One of the two common mutations causing factor XI deficiency in Ashkenazi Jews (type II) is also prevalent in Iraqi Jews, who represent the ancient gene pool of Jews.
Ophthalmic surgery and plasma thromboplastin antecedent (factor XI) deficiency.
Optimal management of an aneurysmal subarachnoid hemorrhage in a patient with known factor XI deficiency: a case report.
Osocimab: A Novel Agent in Preventing Venous Thromboembolism.
Partial and severe factor XI deficiency in South Australia and the usefulness of factor XI mutation analysis for diagnosis.
Patients with severe factor XI deficiency have a reduced incidence of deep-vein thrombosis.
Pedigree analysis of factor XI deficiency in Japanese black cattle.
Percutaneous Coronary Intervention in a Patient with Congenital Factor XI Deficiency and Acquired Inhibitor.
Percutaneous coronary intervention in a patient with factor XI deficiency.
Peri- and Postpartum Management of Patients With Factor XI Deficiency.
Perioperative anesthetic management in a patient with factor XI deficiency undergoing coronary artery bypass graft surgery.
Perioperative management of a redo aortic root replacement in a patient with severe factor XI deficiency.
Perioperative management of factor XI deficiency in a patient undergoing hip arthroplasty.
Perioperative use of modified thrombelastography in factor XI deficiency: a helpful method to assess drug effects.
Peripartum anesthetic management of patients with Factor XI deficiency.
Peripheral retinal vascular lesions in a patient with Gaucher disease and factor XI deficiency. Case report.
Plasma replacement therapy during labor is not mandatory for women with severe factor XI deficiency.
Plasma thromboplastin antecedent deficiency and its association with pseudohemophilia. A report of 2 cases.
Plasma thromboplastin antecedent deficiency and subarachnoid hemorrhage.
Plasma thromboplastin antecedent deficiency.
Plasma thromboplastin antecedent deficiency. Report of a case and review of literature.
Platelet and coagulation studies in Ehlers-Danlos syndrome.
Platelet dysfunction in Noonan's syndrome. A case with a platelet cyclooxygenase-like deficiency and chronic idiopathic thrombocytopenic purpura.
Platelet functional defects in women with unexplained menorrhagia.
Polyphosphate is a cofactor for the activation of factor XI by thrombin.
Postoperative primary adrenal failure from bilateral hemorrhagic adrenal infarction associated with coagulation factor XI deficiency.
Postpartum bleeding in women with inherited bleeding disorders: a matched cohort study.
Postpartum haemorrhage in women with mild factor XI deficiency.
Potential role of recombinant factor VIIa as a hemostatic agent.
Practical guidelines for the clinical use of plasma.
Pregnancy in women with von Willebrand's disease or factor XI deficiency.
Pregnancy outcome in Factor XI deficiency: incidence of miscarriage, antenatal and postnatal haemorrhage in 33 women with Factor XI deficiency.
Preliminary findings of altered follicular activity in Holstein cows with coagulation factor XI deficiency.
Preoperative management of factor XI deficiency with therapeutic plasma exchange: A case report and literature review.
Preoperative screening for coagulopathy using prothrombin time and partial thromboplastin time in patients requiring primary cranial vault remodeling.
Prevalence, causes, and characterization of factor XI inhibitors in patients with inherited factor XI deficiency.
Probable factor XI deficiency in Bantu subjects.
Procainamide-induced circulating anticoagulants in a congenitally-deficient factor XI patient.
Production and therapeutic use of a factor XI concentrate from plasma.
Prolonged activated partial thromboplastin time in pregnancy: a brief report.
PROLONGED BLEEDING TIME IN A PATIENT WITH PLASMA THROMBOPLASTIN ANTECEDENT DEFICIENCY: OBSERVATIONS ON CORRECTION OF THE BLEEDING TIME BY PLATELET TRANSFUSION.
Prophylactic use of desmopressin in surgery of six patients with symptomatic heterozygous factor XI deficiency.
Prospective analysis of factor XI deficiencies in the Marseilles area identified four novel mutations among 12 consecutive unrelated families.
Prostatectomy in factor XI (plasma thromboplastin antecedent) deficiency.
Prostatectomy in factor XI deficiency.
Pulmonary embolism and fatal stroke in a patient with severe factor XI deficiency after bariatric surgery.
Pulmonary embolism with factor XI deficiency.
Pulmonary valvulotomy in Factor XI deficiency.
Rare inherited bleeding disorders secondary to coagulation factors in Jordan: a nine-year study.
Recombinant factor VIIa for the prophylaxis of perioperative hemorrhage in a patient with congenital factor XI deficiency undergoing brain tumor neurosurgery.
Recombinant factor VIIa to prevent surgical bleeding in factor XI deficiency.
Recurrent venous thromboembolic disease and factor XI concentrate in a patient with severe factor XI deficiency, chronic myelomonocytic leukaemia, factor V Leiden and heterozygous plasminogen deficiency.
Reduced fibrinolytic resistance in patients with factor XI deficiency. Evidence of a thrombin-independent impairment of the thrombin-activatable fibrinolysis inhibitor pathway.
Reduced incidence of ischemic stroke in patients with severe factor XI deficiency.
Response to Wiewel-Verschueren S et al.: gynaecological and obstetrical bleeding in women with factor XI deficiency - a systematic review.
Retrospective analysis of 1312 patients with haemophilia and related disorders in a single Chinese institute.
Revisiting the molecular epidemiology of factor XI deficiency: nine new mutations and an original large 4qTer deletion in western Brittany (France).
Screening for bovine leukocyte adhesion deficiency, deficiency of uridine monophosphate synthase, complex vertebral malformation, bovine citrullinaemia, and factor XI deficiency in Holstein cows reared in Turkey.
Screening for factor XI deficiency amongst pregnant women of Ashkenazi Jewish origin.
Sensitivity of three activated partial thromboplastin time reagents to coagulation factor deficiencies.
Severe Ankle Arthritis After Multiple Hemarthrosis Secondary to Factor XI Deficiency: A Case Report.
Severe factor XI deficiency caused by a Gly555 to Glu mutation (factor XI-Glu555): a cross-reactive material positive variant defective in factor IX activation.
Severe factor XI deficiency caused by compound heterozygosity for the type III mutation and a novel insertion in exon 9 (codons 324/325 +G).
Severe factor XI deficiency caused by compound heterozygosity.
Severe factor XI deficiency in a Korean woman with a novel missense mutation (Val498Met) and duplication G mutation in exon 13 of the F11 gene.
Severe factor XI deficiency in a Lebanese family: identification of a novel missense mutation (Trp501Cys) in the catalytic domain.
Severe factor XI deficiency in an Arab family associated with a novel mutation in exon 11.
Severe factor XI deficiency in the Abruzzo region of Italy is associated to different FXI gene mutations.
Severe intraabdominal bleeding after transvaginal oocyte retrieval for IVF-ET and coagulation factor XI deficiency: a case report.
Simulation of normal, carrier and affected controls for large-scale genotyping of cattle for factor XI deficiency.
Simultaneous genotyping of coagulation factor XI type II and type III mutations by multiplex real-time polymerase chain reaction to determine their prevalence in healthy and factor XI-deficient Italians.
Six point mutations that cause factor XI deficiency.
Spectrum of factor XI (F11) mutations in the UK population--116 index cases and 140 mutations.
Spinal Anaesthesia for Caesarean Delivery in a Parturient with Partial Factor XI Deficiency.
Spontaneous hematomyelia secondary to factor XI deficiency. Case report.
Spontaneous spinal epidural hematoma, Brown-Séquard syndrome, and factor XI deficiency.
Spontaneous thrombosis in a patient with factor XI deficiency homozygous for the p.Cys398Tyr mutation.
Sporadic incidence of factor XI deficiency in Holstein cattle
Stereotactic core breast biopsy of a minimal carcinoma complicated by a large hematoma: a management dilemma.
Structural interpretation of 42 mutations causing factor XI deficiency using homology modeling.
Studies on a circulating anticoagulant inhibiting factor XI in a patient with congenital deficiency and carcinoma of the prostate.
Successful childbirth by a patient with congenital factor XI deficiency and an acquired inhibitor.
Successful hemostatic management of major surgery for cervical spondylotic myelopathy in a patient with severe factor XI deficiency.
Successful hip arthroplasty in an adult male with severe factor XI deficiency using Hemoleven(®) , a factor XI concentrate.
Successful perioperative management in a patient with factor XI deficiency.
Successful perioperative management of factor XI deficiency with administration of fresh-frozen plasma in a subdural hematoma patient.
Successful Peritoneal Dialysis Catheter Placement in a New End-Stage Renal Disease Patient with Combined Antiphospholipid Syndrome and Factor XI Deficiency.
Successful resection of sigmoid colon cancer in a patient with factor XI deficiency.
Successful treatment of a lung cancer patient with factor XI deficiency.
Successful Treatment of a Patient with Colon Cancer with Congenital Coagulation Factor XI Deficiency.
Successful use of recombinant factor VIIa (NovoSeven) during cardiac surgery in a pediatric patient with congenital factor XI deficiency.
Successful use of recombinant factor VIIa in a patient with inhibitor secondary to severe factor XI deficiency.
Supernumerary nipples in children with hematologic disorders.
SURGICAL OUTCOMES AFTER MASSIVE SUBRETINAL HEMORRHAGE SECONDARY TO AGE-RELATED MACULAR DEGENERATION.
The activated partial thromboplastin time and factor XI deficiency.
The clinical importance of factor XI deficiency in an Ashkenazi Jewish patient.
The clinical management of factor XI deficiency in pregnant women.
The correction of a hemorrhagic diathesis in preparation for surgery; the correction of plasma thromboplastin antecedent deficiency.
The effect of combined factor XI deficiency with von Willebrand factor abnormalities on haemorrhagic diathesis.
The enigma of severe factor XI deficiency without hemmorrhagic symptoms. Distinction from Hageman factor and "Fletcher factor" deficiency; family study; and problems of diagnosis.
The factor of factor XI deficiency in thyroid neoplasia.
The impact of thrombin generation and rotation thromboelastometry on assessment of severity of factor XI deficiency.
The lipoprotein-associated coagulation inhibitor.
The Management of Factor XI Deficiency in Pregnancy.
The management of factor XI deficiency.
The molecular genetics of factor XI deficiency.
The obstetric experience of women with factor XI deficiency.
The possible role of platelets in bypassing the contact phase of blood coagulation.
The profibrinolytic effect of plasma thrombomodulin in factor XI deficiency and its implications in hemostasis.
The rare inherited coagulation disorders.
The relationship between factor XI coagulant and factor XI antigenic activity in cattle.
The role of recombinant factor VIIa for obstetric block in women with severe factor XI deficiency.
The role of rotational thromboelastometry in assessment of haemostasis during pregnancy in women with factor XI deficiency.
The safety of chronic antithrombotic therapy in patients with factor XI deficiency.
The spectrum of factor XI deficiency in Italy.
The susceptibility of plasma coagulation factor XI to nitration and peroxynitrite action.
The two common mutations causing factor XI deficiency in Jews stem from distinct founders: one of ancient Middle Eastern origin and another of more recent European origin.
The use of desmopressin in congenital factor XI deficiency: a systematic review.
The use of epsilon-aminocaproic acid for the management of hemophilia in dental and oral surgery patients.
The use of fresh blood to control severe haemorrhage associated with massive blood transfusion after cardiopulmonary bypass.
The use of levonorgestrel-releasing intrauterine system for treatment of menorrhagia in women with inherited bleeding disorders.
The use of recombinant factor VIIa (NovoSeven) in a patient with a factor XI deficiency and a circulating anticoagulant.
Therapeutic plasma exchange for perioperative management of patients with congenital factor XI deficiency.
Three Factor 11 Mutations Associated with Factor XI Deficiency in a Turkish Family.
Thrombin generation in patients with factor XI deficiency and clinical bleeding risk.
Thromboembolic phenomena in patients with hereditary factor XI deficiency.
Tissue Factor-Independent Coagulation Correlates with Clinical Phenotype in Factor XI Deficiency and Replacement Therapy.
Tissue-specific expression of functional platelet factor XI is independent of plasma factor XI expression.
Total hip arthroplasty via the direct anterior approach with Kerboull-type acetabular reinforcement device for an elderly female with factor XI deficiency.
Transfer of congenital factor XI deficiency from a donor to a recipient by liver transplantation.
Transfusion-induced specific anti-factor XI inhibitor in a patient with previously unrecognized factor XI deficiency.
Transmission of factor VII deficiency through liver transplantation.
Transurethral prostatectomy in severe factor XI deficiency without bleeding complications.
Traumatic hyphema and factor XI deficiency (hemophilia C).
Treatment of factor XI deficiency.
Treatment of factor XI inhibitor using recombinant activated factor VIIa.
Turning Up to Eleven: Factor XI Inhibitors as Novel Agents to Maximize Safety and Maintain Efficacy in Thromboembolic Disease.
Two common mutations causing factor XI deficiency in Ashkenazi Jews may point to a European origin.
Two factor XI mutations in a Chinese family with factor XI deficiency.
Type I mutation in the F11 gene is a third ancestral mutation which causes factor XI deficiency in Ashkenazi Jews.
Ultrasound-Guided Thrombin Injection for Iliopsoas Pseudoaneurysm.
Undiagnosed bleeding states and medical treatment.
Uneventful cesarean delivery with administration of factor XI concentrate in a patient with severe factor XI deficiency.
Uneventful long-term anticoagulation with fluindione in a patient with severe factor XI deficiency.
Unexpected bleeding after elective nasal surgery.
Unprovoked Pulmonary Embolism in Factor VII Deficiency.
Update on the physiology and pathology of factor IX activation by factor XIa.
Use of recombinant factor VIIa for hip replacement surgery in a patient with severe factor XI deficiency and drug-induced platelet defect.
Variable bleeding manifestations characterize different types of surgery in patients with severe factor XI deficiency enabling parsimonious use of replacement therapy.
Vascular anomaly associated with plasma thromboplastin antecedent deficiency.
When genetic and surname analyses meet historical sources: The C56R mutation associated with factor XI deficiency as a marker of human migration during the Spanish Reconquista.
When the bleeding won't stop: a case report on a patient with hemophilia.
Why factor XI deficiency is a clinical concern.
[A case of a serious clotting defect, without hemorrhagic diathesis, caused by plasma thromboplastin antecedent deficiency.]
[A case of lupoid hepatitis, factor XI deficiency and Hashimoto's disease with circulating anticoagulant]
[A family of congenital factor XI deficiency]
[A rare case of hemorrhagic diathesis caused by plasma thromboplastin antecedent deficiency.]
[A study on platelet Factor XI-like activity in a family with congenital Factor XI deficiency]
[A successful surgical case of atrial septal defect with congenital factor XI deficiency]
[An uncommon cause of hematemesis in children: factor XI deficiency].
[Analysis of a pedigree affected with hereditary coagulation factor XI deficiency due to compound heterozygous variants of F11 gene].
[Anesthesia and perioperative management for cesarean section in patient with factor XI deficiency: a case report].
[Antifibrinolytics as a treatment for severe factor XI deficiency in laryngeal surgery]
[Appropriate laboratory investigation in women with menorrhagia].
[BLOOD COAGULATION IN FACTOR XI DEFICIENCY.]
[Cataract surgery with congenital factor XI deficiency: a case report]
[Congenital deficiency of factor XI: diagnosis and therapy in surgical patients (author's transl)]
[Considerations on plasma thromboplastin antecedent deficiency in rheumatic fever in childhood]
[Epidural anesthesia in a patient with factor XI deficiency]
[Factor XI deficiency caused by a mutation of Gly400Val]
[Factor XI deficiency, a new way of substitution: human purified concentrates]
[Factor XI deficiency: do patients with hemorrhagic diathesis also have hemostasis defects?]
[Factor XI deficiency]
[Familial study of factor XI deficiency. Presurgical prophylactic treatment with desmopressin plus antifibrinolytics]
[FXI gene mutations in two pedigrees of congenital clotting factor XI deficiency]
[Hemophilia C, a deficiency of a contact phase protein which may involve a risk of hemorrhage]
[Hemophilic syndrome of plasma thromboplastin antecedent deficiency; physiopathological and therapeutic aspects.]
[Hemorrhagic disease caused by plasma thromboplastin antecedent deficiency; case report.]
[Hereditary hemorrhagic telangiectasia and congenital factor XI deficiency]
[Identification of compound heterozygous mutations p.Gly400Val and p.Arg532Ter of the F11 gene in a Chinese patient with hereditary factor XI deficiency].
[Identification of novel compound heterozygous variants in a pedigree affected with hereditary coagulation factor XI deficiency].
[Identification of two novel factor XI non-sense mutation Trp228stop and Trp383stop in a Chinese pedigree of congenital factor XI deficiency]
[Inherited bleeding disorders common in Jews].
[Investigation into a family with factor XI deficiency and Willebrand-Jürgens syndrome]
[Isolated increased aPTT with anamnestic hemorrhagic diathesis--severe FXI deficiency]
[Isolated prolongation of the PTT: 2-year retrospective study]
[Labour epidural analgesia for a parturient with a factor XI deficiency: an ill-considered challenge or a reasonable risk?].
[Labour epidural analgesia for a woman with a factor XI deficiency: an illconsidered risk?]
[Menorrhagia and inherited disorders of coagulation]
[Partial familial factor XI deficiency]
[Plasma thromboplastin antecedent deficiency anemia.]
[Polycythemia vera and factor XI deficiency]
[Postoperative haemorrhagia in a girl with congenital factor XI deficiency - successful treatment with desmopressin (DDAVP, Minirin(R))]
[Postoperative hemorrhage due to factor XI deficiency]
[Preoperative disclosing of factor XI deficiency]
[Preoperative monitoring of blood coagulation in urologic operations: diagnosis of familial factor XI deficiency within the scope of preoperative blood coagulation studies]
[Problems posed by factor XI deficiency for the anesthetist (resuscitor)]
[Prolonged activated partial thromboplastin time (aPTT): not always indicative of increased risk of bleeding]
[Retroplacental hematoma and factor XI deficiency]
[Review of patients studied for coagulopathy in a Hematology/Oncology unit].
[Surgical experience in factor XI deficiency]
[The inherited coagulation factor XI deficiency caused by intronic mutation IVS J-4delgttg]
[Thrombocyte dysfunction in children with albinism]
[Thrombocytopenic thrombocytopathy in a case of factor XI deficiency]
[Use of recombinant, activated Factor VII in the treatment and prevention of bleeding complications in two female patients suffering from congenital XI factor deficiency during orthopedic and traumatology intervention. Case reports]
[You make the diagnosis. Heterozygote factor XI deficiency]
Factor XII Deficiency
Activation of factor VII during alimentary lipemia occurs in healthy adults and patients with congenital factor XII or factor XI deficiency, but not in patients with factor IX deficiency.
Combined dys-form of homozygous factor XI deficiency and heterozygous factor XII deficiency.
Factor XI activation in a revised model of blood coagulation.
Factor XI and factor XII as targets for new anticoagulants.
Fibrin formation, fibrinopeptide A release, and platelet thrombus dimensions on subendothelium exposed to flowing native blood: greater in factor XII and XI than in factor VIII and IX deficiency.
Interactions among Hageman factor (HG, Factor XII), plasma thromboplastin antecedent (PTA, Factor XI), plasma prekallikrein (PK, Fletcher factor) and high molecular weight kininogen (HMW-K, Fitzgerald factor) in blood coagulation.
Normal platelet adhesiveness and aggregation in congenital PTA or Hageman factor deficiency.
Polyphosphate is a cofactor for the activation of factor XI by thrombin.
Studies on Fletcher trait and Fitzgerald trait. A rare chance to disclose body´s defense reactions against injury.
[Review of patients studied for coagulopathy in a Hematology/Oncology unit].
[Successes and failures of the activated partial thromboplastin time in the preoperative evaluation]
[Unsuspected prolonged activated partial thromboplastin time in emergency surgery. Diagnostic and therapeutic guide]
Factor XIII Deficiency
An investigation of the spectrum of common and rare inherited coagulation disorders in North-Eastern Iran.
Congenital hemorrhagic disorders in Jordan.
Menorrhagia and reproductive health in rare bleeding disorders: a study from the Indian subcontinent.
Platelet and coagulation studies in Ehlers-Danlos syndrome.
The rare inherited coagulation disorders.
Familial Mediterranean Fever
Comprehensive arrayed primer extension array for the detection of 59 sequence variants in 15 conditions prevalent among the (Ashkenazi) Jewish population.
Mendelian diseases among Roman Jews: implications for the origins of disease alleles.
Fanconi Anemia
Comprehensive arrayed primer extension array for the detection of 59 sequence variants in 15 conditions prevalent among the (Ashkenazi) Jewish population.
Fatty Liver
Prolyl endopeptidase disruption reduces hepatic inflammation and oxidative stress in methionine-choline-deficient diet-induced steatohepatitis.
Prolyl Endopeptidase Gene Disruption Improves Gut Dysbiosis and Non-alcoholic Fatty Liver Disease in Mice Induced by a High-Fat Diet.
Fibromyalgia
Lower serum activity of prolyl endopeptidase in fibromyalgia is related to severity of depressive symptoms and pressure hyperalgesia.
Neuroendocrine and immune aspects of fibromyalgia.
Serum activities of adenosine deaminase, dipeptidyl peptidase IV and prolyl endopeptidase in patients with fibromyalgia: diagnostic implications.
Gaucher Disease
Coexistence of factor XI (plasma thromboplastin antecedent) deficiency and Gaucher's disease.
Comprehensive arrayed primer extension array for the detection of 59 sequence variants in 15 conditions prevalent among the (Ashkenazi) Jewish population.
High incidence of factor XI deficiency in Gaucher's disease.
Peripheral retinal vascular lesions in a patient with Gaucher disease and factor XI deficiency. Case report.
Genetic Diseases, Inborn
Coexistence of factor XI (plasma thromboplastin antecedent) deficiency and Gaucher's disease.
Comparison of in vitro function of neutrophils from cattle deficient in plasma factor XI activity and from normal animals.
Factor XI activity and factor XI antigen in homozygous and heterozygous factor XI deficiency.
Glaucoma
Coexistence of Prader-Willi syndrome, congenital ectropion uveae with glaucoma, and factor XI deficiency.
Glioblastoma
Coagulation factor XIa cleaves the RHDS sequence and abolishes the cell adhesive properties of the amyloid beta-protein.
Glioma
Neuropeptide-metabolizing peptidases in neuro-2a neuroblastoma and C6 glioma cells.
Glomerulonephritis
Nephropathy induced in rats by repeated intravenous injections of rabbit anti-FX1A antibody.
Glomerulonephritis, Membranoproliferative
Acquired factor XI deficiency in a child with membranoproliferative glomerulonephritis.
Glycogen Storage Disease
Comprehensive arrayed primer extension array for the detection of 59 sequence variants in 15 conditions prevalent among the (Ashkenazi) Jewish population.
Glycogen Storage Disease Type III
Comprehensive arrayed primer extension array for the detection of 59 sequence variants in 15 conditions prevalent among the (Ashkenazi) Jewish population.
Hashimoto Disease
[A case of lupoid hepatitis, factor XI deficiency and Hashimoto's disease with circulating anticoagulant]
Hearing Loss, Sensorineural
Comprehensive arrayed primer extension array for the detection of 59 sequence variants in 15 conditions prevalent among the (Ashkenazi) Jewish population.
Heart Failure, Systolic
Active tissue factor and activated factor XI in circulating blood of patients with systolic heart failure due to ischemic cardiomyopathy.
Heart Septal Defects, Atrial
[A successful surgical case of atrial septal defect with congenital factor XI deficiency]
Hemarthrosis
Factor XI deficiency presenting as hemarthrosis during pregnancy.
Hemarthrosis revealing congenital factor XI deficiency.
Severe Ankle Arthritis After Multiple Hemarthrosis Secondary to Factor XI Deficiency: A Case Report.
Hematemesis
[An uncommon cause of hematemesis in children: factor XI deficiency].
Hematologic Diseases
A case of a severe factor XI deficiency in patient undergoing hemodialysis without the use of heparin.
Hematoma, Subdural
Acquired Factor XI Inhibitor Presenting as Spontaneous Bilateral Subdural Hematoma in an Elderly Patient.
Successful perioperative management of factor XI deficiency with administration of fresh-frozen plasma in a subdural hematoma patient.
Hemophilia A
A case of a severe factor XI deficiency in patient undergoing hemodialysis without the use of heparin.
A simple method for analyzing factor IX activation in the patients with hemophilia B variants.
An investigation of the spectrum of common and rare inherited coagulation disorders in North-Eastern Iran.
Anesthetic experience of a patient with hereditary factor XI deficiency (Hemophilia C) : A case report.
Assessment of Actin FS and Actin FSL sensitivity to specific clotting factor deficiencies.
Assessment of menstrual blood loss and gynaecological problems in patients with inherited bleeding disorders.
Blood clotting factor IX BM Nagoya. Substitution of arginine 180 by tryptophan and its activation by alpha-chymotrypsin and rat mast cell chymase.
Cardiovascular surgery in patients with congenital plasma coagulopathies.
Challenges of antithrombotic therapy in the management of cardiovascular disease in patients with inherited bleeding disorders: A single-centre experience.
Clinical and laboratory features of 178 children with recurrent epistaxis.
Combined factor VIII and factor XI congenital deficiency: a case report.
Combined factor VIII/factor XI deficiency may cause intra-familial clinical variability in haemophilia A among Ashkenazi Jews.
Congenital hemorrhagic disorders in Jordan.
Factor XI deficiency and its management.
Factor XI deficiency in Iranians: its clinical manifestations in comparison with those of classic hemophilia.
Fibrin formation, fibrinopeptide A release, and platelet thrombus dimensions on subendothelium exposed to flowing native blood: greater in factor XII and XI than in factor VIII and IX deficiency.
Hemarthrosis revealing congenital factor XI deficiency.
Hemophilia and hemophilia-like diseases caused by deficiencies in plasma thromboplastin factors: anti-hemophilic globulin (AHG), plasma thromboplastin component (PTC) and plasma thromboplastin antecedent (PTA).
Inherited bleeding disorders.
Inhibitors in Patients with Congenital Bleeding Disorders Other Than Hemophilia.
Low endoscopy bleeding risk in patients with congenital bleeding disorders.
Management of menorrhagia in women with inherited bleeding disorders: general principles and use of desmopressin.
Menorrhagia and reproductive health in rare bleeding disorders: a study from the Indian subcontinent.
Menorrhagia from a haematologist's point of view. Part II: management.
Obstetric analgesia and anaesthesia in women with inherited bleeding disorders.
Platelet functional defects in women with unexplained menorrhagia.
Postpartum bleeding in women with inherited bleeding disorders: a matched cohort study.
Pregnancy and oral contraceptives in congenital bleeding disorders of the vitamin K-dependent coagulation factors.
Pregnancy in women with von Willebrand's disease or factor XI deficiency.
Retrospective analysis of 1312 patients with haemophilia and related disorders in a single Chinese institute.
The management of factor XI deficiency.
Thromboembolic phenomena in patients with hereditary factor XI deficiency.
Unprovoked Pulmonary Embolism in Factor VII Deficiency.
Women and inherited bleeding disorders: pregnancy and delivery.
[A case of hemophilia caused by deficiency of plasma thromboplastin antecedent.]
[BLOOD COAGULATION RESEARCH IN 3 CASES OF PTA HEMOPHILIA (CAUSED BY FACTOR XI DEFICIENCY) OF A MAJOR TYPE.]
[Case of hemophilia due to an associated deficiency of antihemophilic globulin and plasma thromboplastin antecedent.]
[Case of sporadic hemophilia caused by deficiency of plasma thromboplastin antecedent and plasma thromboplastin component.]
[Comparison of factor VIII:C and factor IX sensitivity of different commercial APTT reagents for canine plasma]
[Hemophilic patients. Treatment protocol in the dental office]
[Isolated prolongation of the PTT: 2-year retrospective study]
[Unsuspected prolonged activated partial thromboplastin time in emergency surgery. Diagnostic and therapeutic guide]
Hemophilia B
A simple method for analyzing factor IX activation in the patients with hemophilia B variants.
Activation of factor IX by the reaction product of tissue factor and factor VII: additional pathway for initiating blood coagulation.
Activation of factor VII during alimentary lipemia occurs in healthy adults and patients with congenital factor XII or factor XI deficiency, but not in patients with factor IX deficiency.
An investigation of the spectrum of common and rare inherited coagulation disorders in North-Eastern Iran.
Cardiovascular surgery in patients with congenital plasma coagulopathies.
Challenges of antithrombotic therapy in the management of cardiovascular disease in patients with inherited bleeding disorders: A single-centre experience.
Characterization of the defect in activation of factor IX Chapel Hill by human factor XIa.
Clinical and laboratory features of 178 children with recurrent epistaxis.
Congenital hemorrhagic disorders in Jordan.
Factor IX variants of hemophilia B. The effect of activated factor XI and the reaction product of factor VII and tissue factor on the abnormal factor IX molecules.
Fibrin formation, fibrinopeptide A release, and platelet thrombus dimensions on subendothelium exposed to flowing native blood: greater in factor XII and XI than in factor VIII and IX deficiency.
Low endoscopy bleeding risk in patients with congenital bleeding disorders.
Multiple congenital coagulopathies co-expressed with Von Willebrand's disease: the experience of Hemophilia Region III Treatment Centers over 25 years and review of the literature.
Novel missense mutations in two patients with factor XI deficiency (Val271Leu and Tyr351Ser) and one patient with combined factor XI and factor IX deficiency (Phe349Val).
Postpartum bleeding in women with inherited bleeding disorders: a matched cohort study.
The use of epsilon-aminocaproic acid for the management of hemophilia in dental and oral surgery patients.
Therapeutic uses of microencapsulated genetically engineered cells.
[Review of patients studied for coagulopathy in a Hematology/Oncology unit].
Hemorrhagic Disorders
The correction of a hemorrhagic diathesis in preparation for surgery; the correction of plasma thromboplastin antecedent deficiency.
[A case of a serious clotting defect, without hemorrhagic diathesis, caused by plasma thromboplastin antecedent deficiency.]
[A patient with isolated prolongation of aPTT without hemorrhagic diathesis anamnesis: severe, hereditary factor XII deficiency]
[A rare case of hemorrhagic diathesis caused by plasma thromboplastin antecedent deficiency.]
[Factor XI deficiency: do patients with hemorrhagic diathesis also have hemostasis defects?]
Hemostatic Disorders
Factor XI deficiency in an Ashkenazi Jewish child, causing severe postoperative hemorrhage.
Management of factor XI deficiency in oncological liver and colorectal surgery by therapeutic plasma exchange: A case report.
Hepatitis
[A case of lupoid hepatitis, factor XI deficiency and Hashimoto's disease with circulating anticoagulant]
Hepatitis C
Novel serine protease inhibitors.
Hepatomegaly
Alpha 1 antitrypsin deficiency and plasma thromboplastin antecedent deficiency--a new association?
Hernia, Umbilical
A Review of Selected Genes with Known Effects on Performance and Health of Cattle.
Histiocytoma, Malignant Fibrous
Malignant fibrous histiocytoma of the heart complicated by factor XI deficiency in a Jehovah's Witness patient.
Hyperalgesia
Lower serum activity of prolyl endopeptidase in fibromyalgia is related to severity of depressive symptoms and pressure hyperalgesia.
Hyperhomocysteinemia
Risk factors of venous thromboembolism in thai patients.
Hyperlipidemias
Activation of factor VII during alimentary lipemia occurs in healthy adults and patients with congenital factor XII or factor XI deficiency, but not in patients with factor IX deficiency.
Hypertension
Elevated levels of Factor XI are associated with cardiovascular disease in women.
Heart prolyl endopeptidase activity in one-kidney, one clip hypertensive rats.
Hyphema
Traumatic hyphema and factor XI deficiency (hemophilia C).
Hypoprothrombinemias
Autosomal recessive inherited bleeding disorders in Pakistan: a cross-sectional study from selected regions.
Hypotension
The contact system contributes to hypotension but not disseminated intravascular coagulation in lethal bacteremia. In vivo use of a monoclonal anti-factor XII antibody to block contact activation in baboons.
Infarction, Middle Cerebral Artery
Pharmacological studies of a novel prolyl endopeptidase inhibitor, JTP-4819, in rats with middle cerebral artery occlusion.
The kunitz protease inhibitor domain of protease nexin-2 inhibits factor XIa and murine carotid artery and middle cerebral artery thrombosis.
Infections
An intrinsic coagulation pathway inhibitor in a 3-year-old child.
Factor XI and pulmonary infections.
Factor XI Deficiency Alters the Cytokine Response and Activation of Contact Proteases during Polymicrobial Sepsis in Mice.
Inhibition of contact-mediated activation of factor XI protects baboons against S aureus-induced organ damage and death.
Prolyl endopeptidase activity in bronchoalveolar lavage fluid: a novel diagnostic biomarker in a guinea pig model of invasive pulmonary aspergillosis.
Total hip arthroplasty via the direct anterior approach with Kerboull-type acetabular reinforcement device for an elderly female with factor XI deficiency.
Inflammatory Bowel Diseases
Abstracts.
Activated factor XI and tissue factor in inflammatory bowel disease.
Insulinoma
Evidence for pyroglutamyl peptidase I and prolyl endopeptidase activities in the rat insulinoma cell line RINm 5F: lack of relationship with TRH metabolism.
Intracranial Aneurysm
Optimal management of an aneurysmal subarachnoid hemorrhage in a patient with known factor XI deficiency: a case report.
Invasive Pulmonary Aspergillosis
Prolyl endopeptidase activity in bronchoalveolar lavage fluid: a novel diagnostic biomarker in a guinea pig model of invasive pulmonary aspergillosis.
Ischemic Attack, Transient
Elevated factor XI activity levels are associated with an increased odds ratio for cerebrovascular events.
Thromboembolic phenomena in patients with hereditary factor XI deficiency.
Ischemic Stroke
A genome-wide association study identifies KNG1 as a genetic determinant of plasma factor XI Level and activated partial thromboplastin time.
Activated factor IX, factor XI and tissue factor identify patients with permanent atrial fibrillation treated with warfarin who are at risk of ischemic stroke.
Antigen levels of coagulation factor XII, coagulation factor XI and prekallikrein, and the risk of myocardial infarction and ischemic stroke in young women.
Epidemiologic and clinical data linking factors XI and XII to thrombosis.
Genetic Variants of Coagulation Factor XI Show Association with Ischemic Stroke Up to 70 Years of Age.
Genetically Proxied Inhibition of Coagulation Factors and Risk of Cardiovascular Disease: A Mendelian Randomization Study.
Higher risk of ischaemic stroke associated with factor XI levels in dyslipidaemic patients.
Inhibition of Factor XII-Mediated Activation of Factor XI Provides Protection Against Experimental Acute Ischemic Stroke in Mice.
New Horizons in Pharmacologic Therapy for Secondary Stroke Prevention.
Novel hemostatic factor levels and risk of ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) Study.
Percutaneous coronary intervention in a patient with factor XI deficiency.
Reduced incidence of ischemic stroke in patients with severe factor XI deficiency.
The role of haematological traits in risk of ischaemic stroke and its subtypes.
Joint Diseases
Hemophilic arthropathy of the temporomandibular joint: review of the literature, a case report, and discussion.
Severe Ankle Arthritis After Multiple Hemarthrosis Secondary to Factor XI Deficiency: A Case Report.
Kidney Failure, Chronic
PK/PD modeling of FXI antisense oligonucleotides to bridge the dose-FXI activity relation from healthy volunteers to end-stage renal disease patients.
Successful Peritoneal Dialysis Catheter Placement in a New End-Stage Renal Disease Patient with Combined Antiphospholipid Syndrome and Factor XI Deficiency.
Leukemia
Supernumerary nipples in children with hematologic disorders.
The influence of cytostatic treatment on the initiation of plasma coagulation in patients with neoplastic diseases.
Leukemia, Erythroblastic, Acute
Regulation of prolyl endopeptidase activity by the intracellular redox state.
Leukemia, Lymphocytic, Chronic, B-Cell
[Acquired factor XI inhibitor and chronic lymphocytic leukemia.]
Leukemia, Myeloid, Acute
Supernumerary nipples in children with hematologic disorders.
Liver Diseases
Lower activity of serum peptidases in abstinent alcohol-dependent patients.
Prolyl endopeptidase gene disruption attenuates high fat diet-induced nonalcoholic fatty liver disease in mice by improving hepatic steatosis and inflammation.
Prolyl Endopeptidase Gene Disruption Improves Gut Dysbiosis and Non-alcoholic Fatty Liver Disease in Mice Induced by a High-Fat Diet.
Lung Neoplasms
Successful treatment of a lung cancer patient with factor XI deficiency.
Lupus Erythematosus, Systemic
A circulating anticoagulant directed against factor XIa in systemic lupus erythematosus.
A unique precipitating autoantibody against plasma thromboplastin antecedent associated with multiple apparent plasma clotting factor deficiencies in a patient with systemic lupus erythematosus.
Acquired factor XI deficiency in systemic lupus erythematosus.
Acquired Factor XI Inhibitor in Systemic Lupus Erythematosus-Case Report and Literature Review.
Circulating anticoagulant against factor XI and thrombocytopenia with platelet aggregation inhibition in systemic lupus erythematosus.
Circulating anticoagulant against factor XI in psoriasis.
Factor XI deficiency, juvenile rheumatoid arthritis and systemic lupus erythematosus. Report of the first case.
Studies on a circulating anticoagulant in systemic lupus erythematosus: evidence for inhibition of the function of activated plasma thromboplastin antecedent (factor XIa).
Lymphoma
Efficacy of irradiation and external hyperthermia in locally advanced, hormone-refractory or radiation recurrent prostate cancer: a preliminary report.
Mania
Alterations in plasma prolyl endopeptidase activity in depression, mania, and schizophrenia: effects of antidepressants, mood stabilizers, and antipsychotic drugs.
Maple Syrup Urine Disease
A Review of Selected Genes with Known Effects on Performance and Health of Cattle.
Comprehensive arrayed primer extension array for the detection of 59 sequence variants in 15 conditions prevalent among the (Ashkenazi) Jewish population.
Melanoma
Proteolytic activation of tissue plasminogen activator by plasma and tissue enzymes.
Serum activity of prolyl endopeptidase, but not of dipeptidyl peptidase IV, is decreased by immunotherapy with IFN-alpha in high-risk melanoma patients.
Memory Disorders
Isolation of prolyl endopeptidase inhibitory peptides from a sodium caseinate hydrolysate.
Menorrhagia
A case of a severe factor XI deficiency in a Chinese woman with heavy menorrhagia.
Abnormal vaginal bleeding in adolescence as the presenting symptom of a bleeding diathesis.
Bernard-Soulier syndrome (BSS) with uncontrollable menorrhagia.
Bleeding problems in factor XI deficient women.
Factor 11 single-nucleotide variants in women with heavy menstrual bleeding.
The use of levonorgestrel-releasing intrauterine system for treatment of menorrhagia in women with inherited bleeding disorders.
Women and inherited bleeding disorders: menstrual issues.
Mucolipidoses
Comprehensive arrayed primer extension array for the detection of 59 sequence variants in 15 conditions prevalent among the (Ashkenazi) Jewish population.
Myocardial Infarction
Active tissue factor and activated factor XI in circulating blood of patients with systolic heart failure due to ischemic cardiomyopathy.
Antigen levels of coagulation factor XII, coagulation factor XI and prekallikrein, and the risk of myocardial infarction and ischemic stroke in young women.
Elevated levels of plasma prekallikrein, high molecular weight kininogen and factor XI in coronary heart disease.
Epidemiologic and clinical data linking factors XI and XII to thrombosis.
Future prospects for contact factors as therapeutic targets.
Hyperprolactinemia and reduction in plasma titers of Hageman factor, prekallikrein, and high molecular weight kininogen in patients with acute myocardial infarction.
Increased factor XIa levels in patients with a first acute myocardial infarction: the introduction of a new thrombin generation based factor XIa assay.
Inherited factor XI deficiency confers no protection against acute myocardial infarction.
Levels of intrinsic coagulation factors and the risk of myocardial infarction among men: Opposite and synergistic effects of factors XI and XII.
Myocardial infarction in a patient with factor XI deficiency and a lupus anticoagulant.
Myocardial infarctions and other acute coronary syndromes in rare congenital bleeding disorders: a critical analysis of all reported cases.
Percutaneous coronary intervention in a patient with factor XI deficiency.
Reduced incidence of ischemic stroke in patients with severe factor XI deficiency.
Thromboembolic phenomena in patients with hereditary factor XI deficiency.
Myositis Ossificans
Myositis ossificans traumatica. Association with hemophilia (factor XI deficiency) in a football player.
Neoplasm Metastasis
The factor of factor XI deficiency in thyroid neoplasia.
Neoplasms
A case of chronic myelomonocytic leukaemia and factor XI deficiency with a circulating anticoagulant.
Coagulation and oxidative stress plasmatic levels in a type 2 diabetes population.
Combined hereditary factor XI (plasma thromboplastin antecedent) deficiency, von Willebrand's disease, and xeroderma pigmentosum in a Japanese family.
Dipeptidyl peptidase IV, prolyl endopeptidase and cathepsin B activities in primary human lung tumors and lung parenchyma.
Effect of rosuvastatin on risk markers for venous thromboembolism in cancer.
Increased prolyl endopeptidase activity in human neoplasia.
Lower activity of serum peptidases in abstinent alcohol-dependent patients.
Novel Drug Targets for Ischemic Stroke Identified Through Mendelian Randomization Analysis of the Blood Proteome.
Occurrence of blood coagulation factors in situ in small cell carcinoma of the lung.
Prolyl endopeptidase inhibitor Y-29794 blocks the IRS1-AKT-mTORC1 pathway and inhibits survival and in vivo tumor growth of triple-negative breast cancer.
Recurrent venous thromboembolic disease and factor XI concentrate in a patient with severe factor XI deficiency, chronic myelomonocytic leukaemia, factor V Leiden and heterozygous plasminogen deficiency.
Risk factors of venous thromboembolism in thai patients.
The factor of factor XI deficiency in thyroid neoplasia.
Nephritis
A new glomerular antigen in passive Heymann's nephritis.
Treatment of autologous immune complex glomerulonephritis with vasoactive amine antagonists.
Nephritis, Interstitial
A Review of Selected Genes with Known Effects on Performance and Health of Cattle.
Nephrotic Syndrome
Acquired factor XI deficiency in a child with membranoproliferative glomerulonephritis.
Mechanism and significance of kinin formation in nephrotic syndrome.
Nervous System Diseases
Use of Umbrella Sampling to Calculate the Entrance/Exit Pathway for Z-Pro-Prolinal Inhibitor in Prolyl Oligopeptidase.
Neuroblastoma
Neuropeptide-metabolizing peptidases in neuro-2a neuroblastoma and C6 glioma cells.
Prolyl endopeptidase is involved in cellular signalling in human neuroblastoma SH-SY5Y cells.
Neurodegenerative Diseases
Cellular and ultra structural evidence for cytoskeletal localization of prolyl endopeptidase-like protein in neurons.
Effect of prolyl endopeptidase inhibition on arginine-vasopressin and thyrotrophin-releasing hormone catabolism in the rat brain.
Isolation of prolyl endopeptidase inhibitory peptides from a sodium caseinate hydrolysate.
Prolyl Endopeptidase Gene Disruption Improves Gut Dysbiosis and Non-alcoholic Fatty Liver Disease in Mice Induced by a High-Fat Diet.
Non-alcoholic Fatty Liver Disease
Prolyl endopeptidase gene disruption attenuates high fat diet-induced nonalcoholic fatty liver disease in mice by improving hepatic steatosis and inflammation.
Prolyl Endopeptidase Gene Disruption Improves Gut Dysbiosis and Non-alcoholic Fatty Liver Disease in Mice Induced by a High-Fat Diet.
Noonan Syndrome
Hematological findings in Noonan syndrome.
Noonan syndrome: partial factor XI deficiency.
Partial deficiency of coagulation factor XI as a newly recognized feature of Noonan syndrome.
Osteoarthritis
Activities of dipeptidyl peptidase II, dipeptidyl peptidase IV, prolyl endopeptidase, and collagenase-like peptidase in synovial membrane from patients with rheumatoid arthritis and osteoarthritis.
The relationship between collagen metabolism and temporomandibular joint osteoarthrosis in mice.
Osteoarthritis, Hip
Total hip arthroplasty via the direct anterior approach with Kerboull-type acetabular reinforcement device for an elderly female with factor XI deficiency.
Osteopetrosis
A Review of Selected Genes with Known Effects on Performance and Health of Cattle.
Otitis Media
Presence of dipeptidyl peptidase II, dipeptidyl peptidase IV, and prolyl endopeptidase in effusion from patients with serous otitis media.
Otitis Media with Effusion
Presence of dipeptidyl peptidase II, dipeptidyl peptidase IV, and prolyl endopeptidase in effusion from patients with serous otitis media.
Pancytopenia
A genetic predisposition for bovine neonatal pancytopenia is not due to mutations in coagulation factor XI.
Peripheral Arterial Disease
Antithrombotic Agents.
Peritonitis
[Comparative effect of the prolyl endopeptidase inhibitors, benzyloxycarbonyl-prolyl-prolinal and benzyloxycarbonyl-methionyl-cyanopyrrolidine, on the acute exudative inflammation and visceral pain in mice].
phosphorylase kinase deficiency
Factor XI and phosphorylase b kinase deficiency.
plasmin deficiency
Recurrent venous thromboembolic disease and factor XI concentrate in a patient with severe factor XI deficiency, chronic myelomonocytic leukaemia, factor V Leiden and heterozygous plasminogen deficiency.
Platelet Storage Pool Deficiency
Inherited bleeding disorders.
[Thrombocyte dysfunction in children with albinism]
Pneumonia
A Randomized, Placebo-controlled Trial of Roflumilast. Effect on Proline-Glycine-Proline and Neutrophilic Inflammation in Chronic Obstructive Pulmonary Disease.
Factor XI deficiency is not associated with an increased risk of pneumonia and pneumonia-related mortality.
Polycythemia Vera
[Polycythemia vera and factor XI deficiency]
Prader-Willi Syndrome
Coexistence of Prader-Willi syndrome, congenital ectropion uveae with glaucoma, and factor XI deficiency.
Pre-Eclampsia
Preeclampsia in a factor XI deficient woman: discussion about one case.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Supernumerary nipples in children with hematologic disorders.
Pregnancy Complications
Pregnancy outcome in Factor XI deficiency: incidence of miscarriage, antenatal and postnatal haemorrhage in 33 women with Factor XI deficiency.
Protein C Deficiency
Deep venous thrombosis treated by rivaroxaban in a young patient with type Ia carbohydrate-deficient glycoprotein (CDG) syndrome.
Factor XII deficiency acquired by orthotopic liver transplantation: case report and review of the literature.
Risk factors of venous thromboembolism in thai patients.
Transmission of factor VII deficiency through liver transplantation.
Protein S Deficiency
Risk factors of venous thromboembolism in thai patients.
protein-glutamine gamma-glutamyltransferase deficiency
An investigation of the spectrum of common and rare inherited coagulation disorders in North-Eastern Iran.
Congenital hemorrhagic disorders in Jordan.
Menorrhagia and reproductive health in rare bleeding disorders: a study from the Indian subcontinent.
Platelet and coagulation studies in Ehlers-Danlos syndrome.
The rare inherited coagulation disorders.
Proteinuria
Nephropathy induced in rats by repeated intravenous injections of rabbit anti-FX1A antibody.
Psoriasis
Circulating anticoagulant against factor XI in psoriasis.
Pulmonary Disease, Chronic Obstructive
Activated factor XI and tissue factor in chronic obstructive pulmonary disease: links with inflammation and thrombin generation.
N-alpha-PGP and PGP, potential biomarkers and therapeutic targets for COPD.
Pulmonary Embolism
Platelet polyphosphates are proinflammatory and procoagulant mediators in vivo.
Pulmonary embolism and fatal stroke in a patient with severe factor XI deficiency after bariatric surgery.
Pulmonary embolism with factor XI deficiency.
The polyphosphate-factor XII pathway drives coagulation in prostate cancer-associated thrombosis.
Purpura
Co-existence of Bernard Soulier syndrome and factor XI deficiency in a family: a unified pathology?
Purpura, Thrombocytopenic, Idiopathic
Systemic causes of excessive uterine bleeding.
The spectrum of bleeding disorders in women with menorrhagia: a report from Western India.
Purpura, Thrombotic Thrombocytopenic
Factor XI/ADAMTS13 complexes are quantitatively insignificant in human plasma.
Quadriplegia
Spontaneous hematomyelia secondary to factor XI deficiency. Case report.
Reperfusion Injury
Factor XI contributes to myocardial ischemia-reperfusion injury in mice.
Retinal Vein Occlusion
Retinal artery and vein thrombotic occlusion during pregnancy: markers for familial thrombophilia and adverse pregnancy outcomes.
Retrobulbar Hemorrhage
Late retrobulbar hemorrhage and blindness following malar fracture complicated by factor XI deficiency.
Rheumatic Fever
[Considerations on plasma thromboplastin antecedent deficiency in rheumatic fever in childhood]
Sepsis
Coagulation factor XI improves host defence during murine pneumonia-derived sepsis independent of factor XII activation.
Factor XI Deficiency Alters the Cytokine Response and Activation of Contact Proteases during Polymicrobial Sepsis in Mice.
Hemostasis Biomarkers and Risk of Sepsis: the REasons for Geographic And Racial Differences in Stroke (REGARDS) cohort.
Inhibition of contact-mediated activation of factor XI protects baboons against S aureus-induced organ damage and death.
Inhibition of factor XI activation attenuates inflammation and coagulopathy while improving the survival of mouse polymicrobial sepsis.
Simultaneous targeting of CD14 and factor XIa by a fusion protein consisting of an anti-CD14 antibody and the modified second domain of bikunin improves survival in rabbit sepsis models.
Sigmoid Neoplasms
Successful resection of sigmoid colon cancer in a patient with factor XI deficiency.
Spinal Cord Diseases
Factor XI Deficiency in a Patient with Cervical Spondylotic Myelopathy.
Successful hemostatic management of major surgery for cervical spondylotic myelopathy in a patient with severe factor XI deficiency.
Spinal Cord Vascular Diseases
Spontaneous hematomyelia secondary to factor XI deficiency. Case report.
Stomach Neoplasms
One case of rare gastric cancer combined with lack of factor XI.
Polyozellin, a key constituent of the edible mushroom Polyozellus multiplex, attenuates glutamate-induced mouse hippocampal neuronal HT22 cell death.
Stroke
Active tissue factor and activated factor XI in patients with acute ischemic cerebrovascular events.
Association of stroke risk biomarkers with stroke symptoms: the Reasons for Geographic and Racial Differences in Stroke cohort.
Binding of amyloid beta precursor protein to coagulation factor XIa in vivo may favour haemorrhagic stroke.
Circulating activated factor XI and active tissue factor as predictors of worse prognosis in patients following ischemic cerebrovascular events.
Elevated factor XI activity levels are associated with an increased odds ratio for cerebrovascular events.
Future prospects for contact factors as therapeutic targets.
Lack of association of plasma factor XI with incident stroke and coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) Study.
Plasma Kallikrein Contributes to Coagulation in the Absence of Factor XI by Activating Factor IX.
Pulmonary embolism and fatal stroke in a patient with severe factor XI deficiency after bariatric surgery.
Reduced incidence of ischemic stroke in patients with severe factor XI deficiency.
Relation of coagulation factor XI with incident coronary heart disease and stroke: the Cardiovascular Health Study.
Successful Peritoneal Dialysis Catheter Placement in a New End-Stage Renal Disease Patient with Combined Antiphospholipid Syndrome and Factor XI Deficiency.
Subarachnoid Hemorrhage
Optimal management of an aneurysmal subarachnoid hemorrhage in a patient with known factor XI deficiency: a case report.
Plasma thromboplastin antecedent deficiency and subarachnoid hemorrhage.
Syndactyly
A Review of Selected Genes with Known Effects on Performance and Health of Cattle.
Syphilis
Circulating anticoagulant in the procainamide-induced lupus syndrome.
Tay-Sachs Disease
Comprehensive arrayed primer extension array for the detection of 59 sequence variants in 15 conditions prevalent among the (Ashkenazi) Jewish population.
Telangiectasia, Hereditary Hemorrhagic
[Hereditary hemorrhagic telangiectasia and congenital factor XI deficiency]
Telangiectasis
[Hereditary hemorrhagic telangiectasia and congenital factor XI deficiency]
Teratocarcinoma
Engineering a thermostable human prolyl endopeptidase for antibody-directed enzyme prodrug therapy.
Tetanus
Z-321, a prolyl endopeptidase inhibitor, augments the potentiation of synaptic transmission in rat hippocampal slices.
Thrombasthenia
Abnormal vaginal bleeding in adolescence as the presenting symptom of a bleeding diathesis.
Congenital hemorrhagic disorders in Jordan.
Menorrhagia and reproductive health in rare bleeding disorders: a study from the Indian subcontinent.
Molecular genetics aspects of factor XI deficiency and Glanzmann thrombasthenia.
The spectrum of bleeding disorders in women with menorrhagia: a report from Western India.
[Inherited bleeding disorders common in Jews].
Thrombocytopenia
Anaesthesia in a parturient with Noonan's syndrome.
Anaesthetic management of a parturient with severe congenital factor XI deficiency undergoing caesarean section for triplet pregnancy.
Bleeding disorders in Noonan syndrome: three case reports and review of the literature.
Circulating anticoagulant against factor XI and thrombocytopenia with platelet aggregation inhibition in systemic lupus erythematosus.
Clinical and laboratory features of 178 children with recurrent epistaxis.
Thromboembolism
Prospective study of circulating factor XI and incident venous thromboembolism: The Longitudinal Investigation of Thromboembolism Etiology (LITE).
Thrombophilia
Elevation of factor XIa-alpha 1-antitrypsin complex levels in NIDDM patients with diabetic nephropathy.
Factor XI gene analysis in thrombophilia and factor XI deficiency.
High levels of coagulation factor XI as a risk factor for venous thrombosis.
Mannose phosphate isomerase deficiency-congenital disorder of glycosylation (MPI-CDG) with cerebral venous sinus thrombosis as first and only presenting symptom: A rare but treatable cause of thrombophilia.
Prevalence of thrombophilias in patients presenting for bariatric surgery.
Testosterone Therapy Can Interact With Thrombophilia, Leading to Osteonecrosis.
The factor V Leiden mutation, high factor VIII, and high plasminogen activator inhibitor activity: etiologies for sporadic miscarriage.
Thrombophilia-hypofibrinolysis and atherothrombotic cardiovascular disease < or = age 45 years.
Thrombosis
2017 Scientific Sessions Sol Sherry Distinguished Lecture in Thrombosis: Factor XI as a Target for New Anticoagulants.
A factor XIa-activatable hirudin-albumin fusion protein reduces thrombosis in mice without promoting blood loss.
A new manufacturing process to remove thrombogenic factors (II, VII, IX, X, and XI) from intravenous immunoglobulin gamma preparations.
A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo.
A small-molecule factor XIa inhibitor produces antithrombotic efficacy with minimal bleeding time prolongation in rabbits.
Acquired Factor XI Deficiency during SARS-CoV-2 Infection: Not Only Thrombosis.
Activated Factor XI is Increased in Plasma in Response to Surgical Trauma but not to Recombinant Activated FVII-Induced Thrombin Formation.
Activation of the coagulation cascade after infusion of a factor XI concentrate in congenitally deficient patients.
Activity of coagulation factor XI in patients with spontaneous miscarriage: The presence of risk alleles.
Allosteric Inhibition as a New Mode of Action for BAY 1213790, a Neutralizing Antibody Targeting the Activated Form of Coagulation Factor XI.
An update on the pharmaceutical management of thrombosis.
Animal Models of Thrombosis From Zebrafish to Nonhuman Primates: Use in the Elucidation of New Pathologic Pathways and the Development of Antithrombotic Drugs.
Antithrombotic Agents.
Antithrombotic and hemostatic effects of a small molecule factor XIa inhibitor in rats.
Assessing the Coagulation Factor Levels, Inherited Thrombophilia, and ABO Blood Group on the Risk for Venous Thrombosis Among Brazilians.
Asymmetric Synthesis of Silanediol Inhibitors for the Serine Protease Coagulation Cascade Enzyme FXIa.
BAY 1213790, a fully human IgG1 antibody targeting coagulation factor XIa: First evaluation of safety, pharmacodynamics, and pharmacokinetics.
Blood clot formation under flow: the importance of factor XI depends strongly on platelet count.
Blood derived products in pediatrics: New laboratory tools for optimizing potency assignment and reducing side effects.
Cell Receptor and Cofactor Interactions of the Contact Activation System and Factor XI.
Characterisation of a novel series of aprotinin-derived anticoagulants. II. Comparative antithrombotic effects on primary thrombus formation in vivo.
Coagulation factor XI is a contaminant in intravenous immunoglobulin preparations.
Coagulation Factor XI Promotes Distal Platelet Activation and Single Platelet Consumption in the Bloodstream Under Shear Flow.
Coagulation factor XI vaccination: an alternative strategy to prevent thrombosis.
Combined thrombogenic effects of vessel injury, pregnancy and procoagulant immune globulin administration in mice.
Commentary on Acquired Factor XI Deficiency during SARS-CoV-2 Infection: Not Only Thrombosis.
Confocal Blood Flow Videomicroscopy of Thrombus Formation over Human Arteries and Local Targeting of P2X7.
Contact activation of blood coagulation on a defined kaolin/collagen surface in a microfluidic assay.
Design and synthesis of a multivalent catch-and-release assay to measure circulating FXIa.
Design, synthesis and biological evaluation of novel FXIa inhibitors with 2-phenyl-1H-imidazole-5-carboxamide moiety as P1 fragment.
Desmolaris, a novel factor XIa anticoagulant from the salivary gland of the vampire bat (Desmodus rotundus) inhibits inflammation and thrombosis in vivo.
Discovery of a Parenteral Small Molecule Coagulation Factor XIa Inhibitor Clinical Candidate (BMS-962212).
Domain V of beta2-glycoprotein I binds factor XI/XIa and is cleaved at Lys317-Thr318.
Dual inhibition of factor XIIa and factor XIa as a therapeutic approach for safe thromboprotection.
Effects of factor XI deficiency on ferric chloride-induced vena cava thrombosis in mice.
Elevated levels of Factor XI are associated with cardiovascular disease in women.
Elevated plasma factor VIII enhances venous thrombus formation in rabbits: contribution of factor XI, von Willebrand factor and tissue factor.
Enhancement of rabbit jugular vein thrombolysis by neutralization of factor XI. In vivo evidence for a role of factor XI as an anti-fibrinolytic factor.
EP-7041, a Factor XIa Inhibitor as a Potential Antithrombotic Strategy in Extracorporeal Membrane Oxygenation: A Brief Report.
Evaluating prodrug characteristics of a novel anticoagulant fusion protein neorudin, a prodrug targeting release of hirudin variant 2-Lys47 at the thrombosis site, by means of in vitro pharmacokinetics.
Factor XI and factor XII as targets for new anticoagulants.
Factor XI and recurrent venous thrombosis: an observational cohort study.
Factor XI antisense oligonucleotide for prevention of venous thrombosis.
Factor XI as a target for antithrombotic therapy.
Factor XI as a Target for New Anticoagulants.
Factor XI contributes to thrombus propagation on injured neointima of the rabbit iliac artery.
Factor XI deficiency in animal models.
Factor XI deficiency.
Factor XI in haemostasis and thrombosis: past, present and future.
Factor XI inhibition fulfilling the optimal expectations for ideal anticoagulation.
Factor XI Inhibition to Uncouple Thrombosis From Hemostasis: JACC Review Topic of the Week.
Factor XI is a substrate for oxidoreductases: Enhanced activation of reduced FXI and its role in antiphospholipid syndrome thrombosis.
Factor XI regulates pathological thrombus formation on acutely ruptured atherosclerotic plaques.
Factor XI(a) inhibitors for thrombosis: an updated patent review (2016-present).
Factor XI-dependence of surface- and tissue factor-initiated thrombus propagation in primates.
Factor XI-dependent reciprocal thrombin generation consolidates blood coagulation when tissue factor is not available.
Factor XI-related thrombosis and the role of concentrate treatment in factor XI deficiency.
Factor XI: Hemostasis, Thrombosis, and Antithrombosis.
Factor XIa-specific IgG and a reversal agent to probe factor XI function in thrombosis and hemostasis.
Factor XII inhibition reduces thrombus formation in a primate thrombosis model.
First evaluation of the safety, pharmacokinetics and pharmacodynamics of BAY 2433334, a small molecule targeting coagulation factor Xia.
FXIa and platelet polyphosphate as therapeutic targets during human blood clotting on collagen/tissue factor surfaces under flow.
Generation of a 100-billion cyclic peptide phage display library having a high skeletal diversity.
Genetic variants associated with deep vein thrombosis: the F11 locus.
Genetic Variants of Coagulation Factor XI Show Association with Ischemic Stroke Up to 70 Years of Age.
Genome-wide association study with additional genetic and post-transcriptional analyses reveals novel regulators of plasma factor XI levels.
High levels of coagulation factor XI as a risk factor for venous thrombosis.
Higher risk of ischaemic stroke associated with factor XI levels in dyslipidaemic patients.
Identification of coagulation factor XI as a ligand for platelet apolipoprotein E receptor 2 (ApoER2).
Identification of factor XI deficiency in Holstein cattle in Turkey.
In vitro comparison of the effect of two factor XI (FXI) concentrates on thrombin generation in major FXI deficiency.
In Vitro Mode of Action and Anti-thrombotic Activity of Boophilin, a Multifunctional Kunitz Protease Inhibitor from the Midgut of a Tick Vector of Babesiosis, Rhipicephalus microplus.
In vivo coagulation activation following infusion of highly purified factor XI concentrate.
Inhibition of factor XI reduces thrombus formation in rabbit jugular vein under endothelial denudation and/or blood stasis.
Inhibition of Factor XIa Reduces the Frequency of Cerebral Microembolic Signals Derived from Carotid Arterial Thrombosis in Rabbits.
Inhibition of Factor XII-Mediated Activation of Factor XI Provides Protection Against Experimental Acute Ischemic Stroke in Mice.
Intrinsic pathway of coagulation and arterial thrombosis.
Intrinsic Pathway of Coagulation and Thrombosis.
MAA868-a novel FXI antibody with a unique binding mode-shows durable effects on markers of anticoagulation in humans.
Making (anti)sense of factor XI in thrombosis.
Next Generation Antithrombotic Therapy: Focus on Antisense Therapy against Coagulation Factor XI.
Next generation sequencing to dissect the genetic architecture of KNG1 and F11 loci using factor XI levels as an intermediate phenotype of thrombosis.
Ongoing risk of thrombosis with factor XI concentrate: 5 years experience in two centres.
P1 and P2' site mutations convert protease nexin-2 from a factor XIa inhibitor to a plasmin inhibitor.
Patients with severe factor XI deficiency have a reduced incidence of deep-vein thrombosis.
Pharmacological targeting of coagulation factor XI mitigates the development of experimental atherosclerosis in low-density lipoprotein receptor-deficient mice.
Phenylimidazoles as potent and selective inhibitors of coagulation factor XIa with in vivo antithrombotic activity.
Plasma Kallikrein Structure Reveals Apple Domain Disc Rotated Conformation Compared to Factor XI.
Platelet deposition inhibits tissue factor activity: in vitro clots are impermeable to factor Xa.
Polyphosphate is a cofactor for the activation of factor XI by thrombin.
Potent, Orally Bioavailable, and Efficacious Macrocyclic Inhibitors of Factor XIa. Discovery of Pyridine-Based Macrocycles Possessing Phenylazole Carboxamide P1 Groups.
Prevention of vascular graft occlusion and thrombus-associated thrombin generation by inhibition of factor XI.
Recent advances in the discovery and development of factor XI/XIa inhibitors.
Reduced model to predict thrombin and fibrin during thrombosis on collagen/tissue factor under venous flow: Roles of ?'-fibrin and factor XIa.
Selective depletion of factor XI or factor XII with antisense oligonucleotides attenuates catheter thrombosis in rabbits.
Spontaneous thrombosis in a patient with factor XI deficiency homozygous for the p.Cys398Tyr mutation.
Stepwise Reversion of Multiply Mutated Recombinant Antitrypsin Reveals a Selective Inhibitor of Coagulation Factor XIa as Active as the M358R Variant.
Structural Basis for Activity and Specificity of an Anticoagulant Anti-FXIa Monoclonal Antibody and a Reversal Agent.
Targeting factor XI to prevent thrombosis.
The concept and classification of antiphospholipid/cofactor syndromes.
The endogenous thrombin potential and high levels of coagulation factor VIII, factor IX and factor XI.
The Intrinsic Pathway of Coagulation as a Target for Antithrombotic Therapy.
The kunitz protease inhibitor domain of protease nexin-2 inhibits factor XIa and murine carotid artery and middle cerebral artery thrombosis.
The mechanism underlying activation of factor IX by factor XIa.
The rebirth of the contact pathway: a new therapeutic target.
The reduced form of coagulation factor XI is associated with illness severity and coagulopathy in critically-ill septic patients.
The Safety and Efficacy of Novel Agents Targeting Factors XI and XII in Early Phase Human Trials.
Therapeutic strategies for thrombosis: new targets and approaches.
Thromboembolic phenomena in patients with hereditary factor XI deficiency.
Thrombophilia-hypofibrinolysis and atherothrombotic cardiovascular disease < or = age 45 years.
Thrombosis: Targeting factor XIa.
Two novel inhibitory anti-human factor XI antibodies prevent cessation of blood flow in a murine venous thrombosis model.
[A case of congenital factor XI (plasma thromboplastin antecedent) deficiency with large organized thrombus in the vena cava inferior]
[Anticoagulants: current topics].
[Hemocoagulation - New views on the old cascade].
[Laboratory testing for venous thromboembolism]
[Pathology and Mechanisms Underlying Thrombus Formation in Stroke].
Thymoma
Acquired agranulocytosis and factor XI deficiency in association with thymoma.
Tonsillitis
Altered dipeptidyl peptidase IV and prolyl endopeptidase activities in chronic tonsillitis, tonsillar hyperplasia and adenoid hyperplasia.
Triple Negative Breast Neoplasms
Prolyl endopeptidase inhibitor Y-29794 blocks the IRS1-AKT-mTORC1 pathway and inhibits survival and in vivo tumor growth of triple-negative breast cancer.
Urticaria
Interaction between C1-INA, coagulation, fibrinolysis and kinin system in hereditary angioneurotic edema (HANE) and urticaria.
Uterine Hemorrhage
Alpha 1 antitrypsin deficiency and plasma thromboplastin antecedent deficiency--a new association?
Systemic causes of excessive uterine bleeding.
Vascular System Injuries
Combined thrombogenic effects of vessel injury, pregnancy and procoagulant immune globulin administration in mice.
Roles of platelets and factor XI in the initiation of blood coagulation by thrombin.
Zinc (II) selectively enhances the inhibition of coagulation factor XIa by protease nexin-2/amyloid beta-protein precursor.
Venous Thromboembolism
2017 Scientific Sessions Sol Sherry Distinguished Lecture in Thrombosis: Factor XI as a Target for New Anticoagulants.
A genome-wide association study identifies KNG1 as a genetic determinant of plasma factor XI Level and activated partial thromboplastin time.
Abelacimab and factor XI inhibition: a novel mechanism for the prevention of venous thromboembolism.
Abelacimab for Prevention of Venous Thromboembolism.
Anticoagulation therapy: Reducing factor XI with antisense oligonucleotides superior to endoxaparin for postoperative venous thromboembolism.
Antithrombotic Agents.
Co-segregation of thrombophilic disorders in factor V Leiden carriers; the contributions of factor VIII, factor XI, thrombin activatable fibrinolysis inhibitor and lipoprotein(a) to the absolute risk of venous thromboembolism.
Elevated clotting factor levels and venous thrombosis.
Epidemiologic and clinical data linking factors XI and XII to thrombosis.
Factor XI and factor XII as targets for new anticoagulants.
Factor XI deficiency is associated with lower risk for cardiovascular and venous thromboembolism events.
Functional investigation of a venous thromboembolism GWAS signal in a promoter region of coagulation factor XI gene.
Future prospects for contact factors as therapeutic targets.
Genetically Proxied Inhibition of Coagulation Factors and Risk of Cardiovascular Disease: A Mendelian Randomization Study.
Lack of association of plasma factor XI with incident stroke and coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) Study.
Plasma Kallikrein Contributes to Coagulation in the Absence of Factor XI by Activating Factor IX.
Prospective study of circulating factor XI and incident venous thromboembolism: The Longitudinal Investigation of Thromboembolism Etiology (LITE).
Venous Thrombosis
Coagulation factor XI and venous thrombosis.
Congenital factor XI and factor VII deficiencies assure an apparent opposite protection against arterial or venous thrombosis: An intriguing observation.
Design, synthesis, and biological evaluation of peptidomimetic inhibitors of factor XIa as novel anticoagulants.
Elevated factor XI activity levels are associated with an increased odds ratio for cerebrovascular events.
Elevated levels of Factor XI are associated with cardiovascular disease in women.
F11 rs2289252T and rs2036914C Polymorphisms Increase the Activity of Factor XI in Post-trauma Patients with Fractures Despite Thromboprophylaxis.
Factor X levels, polymorphisms in the promoter region of factor X, and the risk of venous thrombosis.
Factor XI and recurrent venous thrombosis: an observational cohort study.
Factor XI antisense oligonucleotide for prevention of venous thrombosis.
Factor XI antisense oligonucleotide for venous thrombosis.
Factor XI as a Therapeutic Target.
Genetic variants associated with deep vein thrombosis: the F11 locus.
High levels of coagulation factor XI as a risk factor for venous thrombosis.
Increased resistance to activated protein C after short-term oral hormone replacement therapy in healthy post-menopausal women.
Inhibition of factor XI reduces thrombus formation in rabbit jugular vein under endothelial denudation and/or blood stasis.
Patients with severe factor XI deficiency have a reduced incidence of deep-vein thrombosis.
Regulation of the f11, klkb1, cyp4v3 gene cluster in livers of metabolically challenged mice.
Role of blood coagulation factor XI in downregulation of fibrinolysis.
Role of Factor XIa and Plasma Kallikrein in Arterial and Venous Thrombosis.
The rebirth of the contact pathway: a new therapeutic target.
Two novel inhibitory anti-human factor XI antibodies prevent cessation of blood flow in a murine venous thrombosis model.
[Laboratory testing for venous thromboembolism]
[Prolonged activated partial thromboplastin time (aPTT): not always indicative of increased risk of bleeding]
Virus Diseases
[Postoperative haemorrhagia in a girl with congenital factor XI deficiency - successful treatment with desmopressin (DDAVP, Minirin(R))]
Vitamin K Deficiency
Systemic causes of excessive uterine bleeding.
von Willebrand Diseases
Abnormal vaginal bleeding in adolescence as the presenting symptom of a bleeding diathesis.
Advances and dilemmas in factor XI.
An investigation of the spectrum of common and rare inherited coagulation disorders in North-Eastern Iran.
Assessment of menstrual blood loss and gynaecological problems in patients with inherited bleeding disorders.
Bernard-Soulier syndrome (BSS) with uncontrollable menorrhagia.
Cardiovascular surgery in patients with congenital plasma coagulopathies.
Challenges of antithrombotic therapy in the management of cardiovascular disease in patients with inherited bleeding disorders: A single-centre experience.
Clinical and laboratory features of 178 children with recurrent epistaxis.
Combined hereditary factor XI (plasma thromboplastin antecedent) deficiency, von Willebrand's disease, and xeroderma pigmentosum in a Japanese family.
Combined severe factor XI deficiency and von Willebrand's disease.
Congenital hemorrhagic disorders in Jordan.
Correction of facial deformities in patients with mild bleeding disorders: a report of three cases.
Definition of the bleeding tendency in factor XI-deficient kindreds--a clinical and laboratory study.
High prevalence of acquired von Willebrand's syndrome in patients with thyroid diseases undergoing thyroid surgery.
Inherited bleeding disorders.
Is the assessment of von Willebrand disease prevalence an achievable challenge? The example of the French Basque Country where blood group O and factor XI deficiency are highly prevalent.
Low endoscopy bleeding risk in patients with congenital bleeding disorders.
Menorrhagia from a haematologist's point of view. Part II: management.
Obstetric analgesia and anaesthesia in women with inherited bleeding disorders.
Platelet dysfunction in Noonan's syndrome. A case with a platelet cyclooxygenase-like deficiency and chronic idiopathic thrombocytopenic purpura.
Postpartum bleeding in women with inherited bleeding disorders: a matched cohort study.
Pregnancy and oral contraceptives in congenital bleeding disorders of the vitamin K-dependent coagulation factors.
Pregnancy in women with von Willebrand's disease or factor XI deficiency.
Preoperative screening for coagulopathy using prothrombin time and partial thromboplastin time in patients requiring primary cranial vault remodeling.
The spectrum of bleeding disorders in women with menorrhagia: a report from Western India.
The use of epsilon-aminocaproic acid for the management of hemophilia in dental and oral surgery patients.
The use of levonorgestrel-releasing intrauterine system for treatment of menorrhagia in women with inherited bleeding disorders.
Unprovoked Pulmonary Embolism in Factor VII Deficiency.
Women and inherited bleeding disorders - A review with a focus on key challenges for 2019.
Women and inherited bleeding disorders: menstrual issues.
Women and inherited bleeding disorders: pregnancy and delivery.
[Appropriate laboratory investigation in women with menorrhagia].
[Isolated prolongation of the PTT: 2-year retrospective study]
[Menorrhagia and inherited disorders of coagulation]
[Successes and failures of the activated partial thromboplastin time in the preoperative evaluation]
[Unsuspected prolonged activated partial thromboplastin time in emergency surgery. Diagnostic and therapeutic guide]
Xeroderma Pigmentosum
Combined hereditary factor XI (plasma thromboplastin antecedent) deficiency, von Willebrand's disease, and xeroderma pigmentosum in a Japanese family.