3.4.21.27: coagulation factor XIa
This is an abbreviated version!
For detailed information about coagulation factor XIa, go to the full flat file.
Word Map on EC 3.4.21.27
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3.4.21.27
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bleeding
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thrombin
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clot
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platelet
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thrombosis
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anticoagulant
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prothrombin
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kallikrein
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kininogen
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prekallikrein
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viii
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hemostasis
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venous
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fibrinogen
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antithrombin
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zymogen
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fibrinolysis
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procoagulant
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fibrin
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willebrand
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antithrombotic
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hemophilia
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thromboembolism
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plasmin
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ashkenazi
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fxiia
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hageman
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coagulopathy
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amidolytic
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diathesis
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haemostat
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thrombophilias
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leiden
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jewish
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antifibrinolytic
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kaolin
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proline-specific
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thrombin-activatable
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meningosepticum
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fletcher
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c1-inhibitor
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thromboelastometry
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drug development
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tenase
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medicine
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basque
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menorrhagia
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desmopressin
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tranexamic
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proline-containing
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tafi
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recalcified
- 3.4.21.27
- bleeding
- thrombin
- clot
- platelet
- thrombosis
-
anticoagulant
- prothrombin
- kallikrein
- kininogen
- prekallikrein
- viii
-
hemostasis
- venous
- fibrinogen
- antithrombin
- zymogen
-
fibrinolysis
-
procoagulant
- fibrin
- willebrand
-
antithrombotic
- hemophilia
- thromboembolism
- plasmin
-
ashkenazi
- fxiia
-
hageman
- coagulopathy
-
amidolytic
- diathesis
-
haemostat
- thrombophilias
- leiden
-
jewish
-
antifibrinolytic
- kaolin
-
proline-specific
-
thrombin-activatable
- meningosepticum
-
fletcher
- c1-inhibitor
-
thromboelastometry
- drug development
-
tenase
- medicine
-
basque
- menorrhagia
- desmopressin
-
tranexamic
-
proline-containing
- tafi
-
recalcified
Reaction
Selective cleavage of Arg-/-Ala and Arg-/-Val bonds in factor IX to form factor IXa =
Synonyms
activated blood-coagulation factor XI, activated coagulation factor XIa, activated factor XI, activated factor XIa, activated FXI, activated plasma thromboplastin antecedent, blood coagulation factor XIa, blood-coagulation factor XI, activated, blood-coagulation factor XIa, coagulation factor XI, coagulation factor XIa, factor XI, factor XIa, factor XIa catalytic domain, FXI, FXIa, fXIaCD, More, plasma thromboplastin antecedent, prolyl endopeptidase, protease factor XIa, PTA, recombinant human FXI370-607, rhFXI370-607
ECTree
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Source Tissue
Source Tissue on EC 3.4.21.27 - coagulation factor XIa
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additional information
the enzyme binds to platelets, a conformational transition accompanies conversion of factor XI to factor XIa that conceals the Apple 3 domain zymogen factor XI platelet binding site and exposes the factor XIa platelet binding site within the catalytic domain possibly comprising residues Cys527-Cys542, overview
additional information
hemophilia C (deficiency in FXI) is present in both sexes
additional information
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hemophilia C (deficiency in FXI) is present in both sexes