Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

3.4.21.27: coagulation factor XIa

This is an abbreviated version!
For detailed information about coagulation factor XIa, go to the full flat file.

Word Map on EC 3.4.21.27

Reaction

Selective cleavage of Arg-/-Ala and Arg-/-Val bonds in factor IX to form factor IXa =

Synonyms

activated blood-coagulation factor XI, activated coagulation factor XIa, activated factor XI, activated factor XIa, activated FXI, activated plasma thromboplastin antecedent, blood coagulation factor XIa, blood-coagulation factor XI, activated, blood-coagulation factor XIa, coagulation factor XI, coagulation factor XIa, factor XI, factor XIa, factor XIa catalytic domain, FXI, FXIa, fXIaCD, More, plasma thromboplastin antecedent, prolyl endopeptidase, protease factor XIa, PTA, recombinant human FXI370-607, rhFXI370-607

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.27 coagulation factor XIa

Purification

Purification on EC 3.4.21.27 - coagulation factor XIa

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
affinity chromatography
affinity chromatography with antibody 5F7, gel filtration
-
antibody-affinity chromatography by using the calcium-dependent anti-human fIX monoclonal IgG SB 249417
-
immobilized Zn2-chelate chromatography and cation exchange chromatography
-
light chain
-
method not mentioned
native enzyme from plasma and recombinant wild-type and mutant enzymes from HEK-293 cells by immunoaffinity chromatography with elution by benzamidine
-
Ni-NTA column chromatography
recombinant mutant enzyme C362S/C482S from HEK-293 cells by immunoaffinity chromatography
recombinant wild-type and mutant enzymes from HEK-293 cells by immunoaffinity chromatography
recombinant wild-type and mutant enzymes from HEK-293 cells by immunoaffinity, cation exchange, and heparin affinity chromatography
SP-Sepharose column chromatography, Heparin HiTrap column chromatography and Superdex 75 column chromatography
-
Zn2+-chelating Sepharose column chromatography and SP Sepharose column chromatography