3.1.6.12: N-acetylgalactosamine-4-sulfatase

This is an abbreviated version!
For detailed information about N-acetylgalactosamine-4-sulfatase, go to the full flat file.

Word Map on EC 3.1.6.12

3.1.6.12

mucopolysaccharidosis

lysosomal

maroteaux-lamy

glycosaminoglycans

arylsulfatase

dermatan

feline

rhasb

medicine

galsulfase

sulfatases

stair

enzyme-replacement

mps-vi

dysostosis

diagnostics

nutrition

Reaction

Synonyms

4-sulfatase, 4-sulphatase, acetylgalactosamine 4-sulfatase, ARSB, arylsulfatase B, ASB, chondroitinase, chondroitinsulfatase, chondrosulfatase, G4S, gastric chondrosulfohydrolase, N-acetylgalactosamine 4-sulfatase, N-acetylgalactosamine 4-sulfate sulfohydrolase, N-acetylgalactosamine-4-sulfatase, N-acetylgalactosamine-4-sulphatase, sulfatase, acetylgalactosamine 4-

ECTree

3 Hydrolases

3.1 Acting on ester bonds

3.1.6 Sulfuric-ester hydrolases

3.1.6.12 N-acetylgalactosamine-4-sulfatase

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Results	in table
7	Activating Compound
120	AA Sequence
21	Application
1	CAS Registry Number
14	Cloned(Commentary)
1	Crystallization (Commentary)
410	Disease/ Diagnostics
2	Expression
23	General Information
2	General Stability
35	Inhibitors
1	Ki Value [mM]
21	KM Value [mM]
22	Localization
13	Metals/Ions
29	Molecular Weight [Da]
45	Natural Substrates/ Products (Substrates)
67	Organism
1	Oxidation Stability
2	Pathway
3	PDB ID
18	pH Optimum
4	pH Range
1	pH Stability
5	Posttranslational Modification
101	Protein Variants
15	Purification (Commentary)
1	Reaction
1	Reaction Type
67	Reference
85	Source Tissue
11	Specific Activity [micromol/min/mg]
2	Storage Stability
128	Substrates and Products (Substrate)
11	Subunits
64	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
16	Temperature Stability [°C]
1	Turnover Number [1/s]

pH Optimum

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pH Optimum on EC 3.1.6.12 - N-acetylgalactosamine-4-sulfatase

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3.5

Homo sapiens

UDP-N-acetylgalactosamine 4-sulfate

135548

3.8

Homo sapiens

oligosaccharide substrate, formate buffer

4 - 4.8

substrate-dependent

4.4

oligosaccharide substrate, acetate buffer or dimethylglutarate buffer

135542

4.8

Gallus gallus

chondroitin 4-sulfate

135552

2 entries

5.3

Homo sapiens

wild-type and mutant enzyme

654646

5.5

Homo sapiens

4-methylumbelliferyl sulfate

5.6

5.7

enzyme from animals without infection, maximal activity is about 60% of the activity of the enzyme from animals infected with Schistosoma mansoni

655942

6.1

Homo sapiens

nitrocatechol sulfate

135544

Mus musculus

enzyme from animals infected with Schistosoma mansoni

655942

8.2

Homo sapiens

assay at

707109