1.1.1.43: phosphogluconate 2-dehydrogenase

This is an abbreviated version, for detailed information about phosphogluconate 2-dehydrogenase, go to the full flat file.

Reaction

6-phospho-D-gluconate
+
NAD(P)+
=
6-phospho-2-dehydro-D-gluconate
+
NAD(P)H
+
H+

Synonyms

2-keto-6-phosphogluconate reductase, 6-PGADHase, 6-PGDase, 6-PGDH, 6-phosphogluconate dehydrogenase, 6-phosphogluconate dehydrogenase (NAD), 6-phosphogluconate-dehydrogenase, 6-phosphogluconic dehydrogenase, 6-phosphoglucuronic acid dehydrogenase, 6PGAD, 6PGD, 6PGDH, gluconate 6-phosphate dehydrogenase, phosphogluconate dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.43 phosphogluconate 2-dehydrogenase

Source Tissue

Source Tissue on EC 1.1.1.43 - phosphogluconate 2-dehydrogenase

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
a 6PGD gene expression pattern in ovines differing in weight is not followed by analogous changes of its enzymatic activity suggesting that other post transcription or post translation regulation is involved
Manually annotated by BRENDA team
-
of pregnant and nonpregnant women, enzyme undergoes retrograde transport to the microtubule-organizing centers in neutrophils from pregnant women, can be blocked by colchicine, anterograde distribution in cells from nonpregnant women
Manually annotated by BRENDA team
-
from seedlings
Manually annotated by BRENDA team