Information on EC 1.1.1.43 - phosphogluconate 2-dehydrogenase

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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria

EC NUMBER
COMMENTARY
1.1.1.43
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RECOMMENDED NAME
GeneOntology No.
phosphogluconate 2-dehydrogenase
REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
6-phospho-D-gluconate + NAD(P)+ = 6-phospho-2-dehydro-D-gluconate + NAD(P)H + H+
show the reaction diagram
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REACTION TYPE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
oxidation
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redox reaction
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reduction
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PATHWAY
KEGG Link
MetaCyc Link
glucose degradation (oxidative)
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Glutathione metabolism
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Metabolic pathways
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Microbial metabolism in diverse environments
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Pentose phosphate pathway
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SYSTEMATIC NAME
IUBMB Comments
6-phospho-D-gluconate:NAD(P)+ 2-oxidoreductase
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SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
2-keto-6-phosphogluconate reductase
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6-PGADHase
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6-PGDase
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6-phosphogluconate dehydrogenase
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6-phosphogluconate dehydrogenase
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6-phosphogluconate dehydrogenase
Tripsacum dactyloides, Zea mays, Zea mays x Tripsacum dactyloides
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6-phosphogluconate dehydrogenase (NAD)
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6-phosphogluconate-dehydrogenase
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6-phosphogluconate-dehydrogenase
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6-phosphogluconic dehydrogenase
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6-phosphoglucuronic acid dehydrogenase
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6PGDH
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6PGDH
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gluconate 6-phosphate dehydrogenase
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phosphogluconate dehydrogenase
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CAS REGISTRY NUMBER
COMMENTARY
9001-82-5
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ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
Ankistrodesmus braunii
C.C.A.P 202/7C
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Manually annotated by BRENDA team
Ankistrodesmus braunii C.C.A.P 202/7C
C.C.A.P 202/7C
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Manually annotated by BRENDA team
ATCC 17616, synonymous with Pseudomonas cepacia
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Manually annotated by BRENDA team
methanol utilizing yeast
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Manually annotated by BRENDA team
yeast, strain pK 233
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Manually annotated by BRENDA team
wild-type strain 2192, mutant strains nit A and nit B
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Manually annotated by BRENDA team
pregnant and nonpregnant women
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Manually annotated by BRENDA team
sea urchin
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Manually annotated by BRENDA team
sheep
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Manually annotated by BRENDA team
strain A 3.12
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Manually annotated by BRENDA team
Pseudomonas fluorescens A 3.12
strain A 3.12
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Manually annotated by BRENDA team
Pseudomonas sp. W5
W5
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Manually annotated by BRENDA team
castor bean
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Manually annotated by BRENDA team
maize, L. Pioneer HiBred International line B73
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Manually annotated by BRENDA team
Zea mays x Tripsacum dactyloides
hybrid, isozyme
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Manually annotated by BRENDA team
GENERAL STABILITY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
20% glycerol stabilizes the enzyme
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STORAGE STABILITY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
0°C both 6-phosphogluconate dehydrogenase species obtained by treatment with ammonium sulfate retain 100% of their activity when stored for several months
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0°C freezing preserves activity for several days
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Cloned/COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
expressed in Escherichia coli BL21(DE3) cells
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APPLICATION
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
additional information
Tripsacum dactyloides, Zea mays, Zea mays x Tripsacum dactyloides
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usage of isozymes as marker for chromosome identification and evaluation of introgression of genes in apomictic mode of reproduction of Tripsacum dactyloides into Zea mays