1.1.1.43: phosphogluconate 2-dehydrogenase

This is an abbreviated version, for detailed information about phosphogluconate 2-dehydrogenase, go to the full flat file.

Reaction

6-phospho-D-gluconate
+
NAD(P)+
=
6-phospho-2-dehydro-D-gluconate
+
NAD(P)H
+
H+

Synonyms

2-keto-6-phosphogluconate reductase, 6-PGADHase, 6-PGDase, 6-PGDH, 6-phosphogluconate dehydrogenase, 6-phosphogluconate dehydrogenase (NAD), 6-phosphogluconate-dehydrogenase, 6-phosphogluconic dehydrogenase, 6-phosphoglucuronic acid dehydrogenase, 6PGAD, 6PGD, 6PGDH, gluconate 6-phosphate dehydrogenase, phosphogluconate dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.43 phosphogluconate 2-dehydrogenase

Molecular Weight

Molecular Weight on EC 1.1.1.43 - phosphogluconate 2-dehydrogenase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
40000
-
2 * 40000, enzyme active with NAD+
47000
-
2 * 47000, SDS-PAGE
56000
-
2 * 56000, SDS-PAGE
57000
-
2 * 57000
58000
-
x * 58000, SDS-PAGE
60000
-
2 * 60000, enzyme specific for NADP+
82000
-
enzyme active with NAD+, sucrose density gradient sedimentation
84000
-
enzyme active with NAD+, gel filtration
92000
-
PAGE
94000
-
sedimention-equilibrium measurement by the meniscus-depletion method, initial protein concentration 0.2 mg/ml
95000
-
gel filtration
98000
-
sedimention-equilibrium measurement by the meniscus-depletion method, initial protein concentration 0.4 mg/ml
110000 - 120000
-
NADP+-specific enzyme
110000
120000
-
NADP+-specific enzyme, gel filtration
123000
-
NADP+-specific enzyme, sucrose density gradient sedimentation
129000
-
short-column equilibrium sedimentation
220000
-
gel filtration