Disease on EC 1.1.1.43 - phosphogluconate 2-dehydrogenase

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DISEASE
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Abortion, Spontaneous
[Role of disorders of pentosephosphate pathway of glucose oxidation in the pathogenesis of the arrest of fetal development in miscarriage]
Acidosis
Stimulation of rat-kidney hexose monophosphate shunt dehydrogenase activity by chronic metabolic acidosis.
Acquired Immunodeficiency Syndrome
Escherichia coli 6-phosphogluconate dehydrogenase aids in tellurite resistance by reducing the toxicant in a NADPH-dependent manner.
Slow-binding inhibition of 6-phosphogluconate dehydrogenase by zinc ion.
Alzheimer Disease
Crystal structure of Saccharomyces cerevisiae 6-phosphogluconate dehydrogenase Gnd1.
Increased cerebral glucose-6-phosphate dehydrogenase activity in Alzheimer's disease may reflect oxidative stress.
Anemia
Effect of anaemia on red cell metabolism in cattle.
The relationship between red cell aging and enzyme activities in experimental animals.
Anemia, Hemolytic
Congenital 6-phosphogluconate dehydrogenase (6PGD) deficiency associated with chronic hemolytic anemia in a Spanish family.
[6 cases of inherited nonspherocytic hemolytic anemia associated with a deficit of 6-phosphogluconate dehydrogenase in the erythrocytes]
[Congenital nonspherocytic hemolytic anemia with incomplete deficiency of 6-phosphogluconate dehydrogenase]
Anemia, Hemolytic, Congenital
[Hereditary hemolytic anemia associated with insufficient activity of 6-phosphogluconate dehydrogenase of erythrocytes with hemoglobinuria following administration of drugs]
Anemia, Hemolytic, Congenital Nonspherocytic
[Congenital nonspherocytic hemolytic anemia with incomplete deficiency of 6-phosphogluconate dehydrogenase]
Anemia, Iron-Deficiency
The investigation of plasma glucose-6-phosphate dehydrogenase, 6-phoshogluconate dehydrogenase, glutathione reductase in premenauposal patients with iron deficiency anemia.
Arsenic Poisoning
[Glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase activity in arsenic poisoning and in hypoxemia caused by sodium nitrite.]
Ascorbic Acid Deficiency
Phagocytosis and leukocyte enzymes in ascorbic acid deficient guinea pigs.
Avitaminosis
[Limited-time feeding ("meal-feeding") and avitaminosis A : respiratory exchange and metabolic adaptation in rats]
beta-Thalassemia
[Study of the enzymatic activities in the erythrocytes and platelets of subjects with Mediterranean anemia. V. Glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase activities of thalassemic platelets]
Breast Neoplasms
Effects of opiates and naloxone on certain enzymes of carbohydrate metabolism in human breast carcinomas.
The effects of the administration of tamoxifen, ethynyloestradiol, and prednisolone on the activities of certain enzymes of carbohydrate metabolism in primary human breast carcinomas in vivo.
The value of 6-phosphogluconate dehydrogenase (6-PGDH) activity as a marker of tumour cellularity and prognostic indicator in primary breast cancer.
Carcinogenesis
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Carcinoma
A randomized clinical trial to investigate the usefulness of the addition of prednisolone to tamoxifen as adjuvants to mastectomy in primary breast cancer patients with a high risk of recurrence: a preliminary report.
Determination of 6-PGDH in the vaginal secretions of patients with carcinoma of the cervix. A new method of collection of vaginal secretions.
Enzyme studies in human prostatic tissues.
Evaluation of 6-phosphogluconate dehydrogenase in carcinoma in situ of the cervix.
The early diagnosis of carcinoma of the female genital tract. I. 6-phosphogluconate dehydrogenase activity and carcinoma of the female genital tract.
The early diagnosis of carcinoma of the female genital tract. II. Vaginal fluid 6-phosphogluconate dehydrogenase activity as a test for carcinoma of the cervix.
The effects of the administration of tamoxifen, ethynyloestradiol, and prednisolone on the activities of certain enzymes of carbohydrate metabolism in primary human breast carcinomas in vivo.
USE OF 6-PHOSPHOGLUCONATE DEHYDROGENASE AS A SCREEN TEST FOR CERVICAL CARCINOMA IN NORMAL WOMEN.
[Histoenzymatic studies of cervical carcinoma. II. Glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, TPN diaphorase and DPN diaphorase]
[Is a diagnosis of genital carcinomas by determination of the 6-phosphogluconate dehydrogenase activity of vaginal secretion possible?]
[Our experience with the glucose-6-phosphate and 6-phosphogluconate dehydrogenase tests in the diagnosis of gynecologic carcinoma]
Carcinoma in Situ
Evaluation of 6-phosphogluconate dehydrogenase in carcinoma in situ of the cervix.
Carcinoma, Hepatocellular
Post-translational regulation of glucose-6-phosphate dehydrogenase activity in (pre)neoplastic lesions in rat liver.
Uridine and cytidine nucleotide synthesis in renal hypertrophy: biochemical differences in response to the growth stimulus of diabetes and unilateral nephrectomy.
[Activities of dehydrogenases of the pentose phosphate pathway and transketolase in transplanted mouse hepatomas with different growth rates and in organs of tumor carriers]
Cataract
Enzyme activities in human lens epithelium of age-related cataract.
Cervical Intraepithelial Neoplasia
Increased activity of 6-phosphogluconate dehydrogenase and glucose-6-phosphate dehydrogenase in purified cell suspensions and single cells from the uterine cervix in cervical intraepithelial neoplasia.
Chagas Disease
The 6-phosphogluconate dehydrogenase from Trypanosoma cruzi: the absence of two inter-subunit salt bridges as a reason for enzyme instability.
Chemical and Drug Induced Liver Injury
[Catalytic properties of 6-phosphogluconate dehydrogenase from rat liver in normal state and during toxic hepatitis]
Cysts
A full set of monosomic addition lines in Beta vulgaris from Beta webbiana: morphology and isozyme markers.
Some glucose metabolic enzymes in various fractions of sarcocysts of Sarcocystis fusiformis of buffalo (Bubalus bubalis).
Dermatitis, Contact
[Enzymatic activity of the pentosephosphate pathway of carbohydrate conversion in the experimental therapy of dermatitis in rats]
Down Syndrome
6-phosphogluconate dehydrogenase (6-P-GD) in Down's syndrome.
Duodenal Ulcer
[Characteristics of the pentose phosphate pathway of carbohydrate metabolism in the gastric mucosa of persons with peptic ulcer]
Fatty Liver
Biochemical changes in liver and blood during liver fattening in rats.
glucose-6-phosphate dehydrogenase (nadp+) deficiency
Canine malignant hyperthermia susceptibility: erythrocytic defects--osmotic fragility, glucose-6-phosphate dehydrogenase deficiency and abnormal Ca2+ homeostasis.
The detection of glucose-6-phosphate dehydrogenase deficiency in mediterraneans by comparative quantitative enzyme electrophoresis.
The Thai variant and the distribution of alleles of 6-phosphogluconate dehydrogenase and the distribution of glucose 6-phosphate dehydrogenase deficiency in Thailand.
Glucosephosphate Dehydrogenase Deficiency
Canine malignant hyperthermia susceptibility: erythrocytic defects--osmotic fragility, glucose-6-phosphate dehydrogenase deficiency and abnormal Ca2+ homeostasis.
The detection of glucose-6-phosphate dehydrogenase deficiency in mediterraneans by comparative quantitative enzyme electrophoresis.
glutathione-disulfide reductase deficiency
Visual test for erythrocytic glucose-6-phosphate dehydrogenase, 6-phosphogluconic dehydrogenase, and glutathione reductase deficiencies.
Hemoglobinuria
[Hereditary hemolytic anemia associated with insufficient activity of 6-phosphogluconate dehydrogenase of erythrocytes with hemoglobinuria following administration of drugs]
Infection
Cloning, expression and characterization of a cell wall surface protein, 6-phosphogluconate dehydrogenase, of Haemophilus parasuis.
Cloning, expression and characterization of a cell wall surface protein, 6-phosphogluconate-dehydrogenase, of Streptococcus suis serotype 2.
Effect of schistosomal infection and its treatment on some key enzymes of glucose metabolism in mice livers.
Effects of 5,8-dimethylthieno[2,3-b]quinoline-2-carboxylic acid on the antioxidative defense and lipid membranes in Plasmodium berghei-infected erythrocytes.
Evidence for dimer/tetramer equilibrium in Trypanosoma brucei 6-phosphogluconate dehydrogenase.
[Glycolysis and pentose-phosphate pathway ratio in staphylococcus from the female genitalia in norm and dysbiosis]
Ketosis
[Glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase activity in animals with experimental ketosis]
Laryngeal Neoplasms
[Activity of the enzymatic antioxidant system depends on the clinical stage of laryngeal cancer ]
Leishmaniasis, Cutaneous
Isoenzyme characterization of Leishmania isolated from human cases with localized cutaneous leishmaniasis from the State of Campeche, Yucatan Peninsula, Mexico.
[Leishmania infantum Nicolle, 1908, the agent of the autochthonous oriental sore. Apropos of the biochemical identification of 2 strains isolated in the eastern Pyrenees]
Leprosy
Genetic markers and leprosy in South African negroes: Part II. Erythrocyte enzyme polymorphisms.
Leukemia
6-phosphogluconate dehydrogenase: hemizygous manifestation in a patient with leukemia.
Enzyme activities of NADPH-forming metabolic pathways in normal and leukemic leukocytes.
Targeting 6-phosphogluconate dehydrogenase in the oxidative PPP sensitizes leukemia cells to antimalarial agent dihydroartemisinin.
Leukemia, Myeloid, Acute
Enzyme activities of NADPH-forming metabolic pathways in normal and leukemic leukocytes.
Lung Neoplasms
Glycolytic cancer cells lacking 6-phosphogluconate dehydrogenase metabolize glucose to induce senescence.
One-step purification of soluble recombinant human 6-phosphogluconate dehydrogenase from Escherichia coli.
Malaria
An electron cytochemical study of 6-phosphogluconate dehydrogenase activity in infected erythrocytes during malaria.
Resistance to falciparum malaria among adults in central Sudan.
Studies on enzyme variation in the murine malaria parasites Plasmodium berghei, P. yoelii, P. vinckei and P. chabaudi by starch gel electrophoresis.
Muscular Atrophy
Activities of some antioxidative and hexose monophosphate shunt enzymes of skeletal muscle in neuromuscular diseases.
Muscular Diseases
The inhibitory effect of actinomycin D and cycloheximide on the increase in activity of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase in experimentally induced diseased skeletal muscles.
[The activity of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase in skeletal muscle tissues of patients with muscular diseases]
Muscular Dystrophy, Duchenne
Changes in some cytoplasmic enzymes from red cells fractionated into age groups by centrifugation in Ficoll/Triosil gradients. Comparison of normal humans and patients with Duchenne muscular dystrophy.
Myositis
Additional biochemical criteria in the differential diagnosis of myositis.
Neoplasm Metastasis
Experimentally induced colon cancer metastases in rat liver increase the proliferation rate and capacity for purine catabolism in liver cells.
Neoplasms
6-PHOSPHOGLUCONATE DEHYDROGENASE ACTIVITY IN VAGINAL FLUID: LIMITATIONS AS A SCREENING TEST FOR GENITAL CANCER.
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
6-Phosphogluconate dehydrogenase regulates tumor cell migration in vitro by regulating receptor tyrosine kinase c-Met.
6-phosphogluconate dehydrogenase, glucose-6-phosphate dehydrogenase, glucose-6-phosphate isomerase, and hexokinase activity ratios in some human tumor cytosols.
A modified assay for 6-phosphogluconate dehydrogenase in samples of vaginal fluid from women with and without gynecologic cancer.
A new enzyme test for gynaecological cancer. 6-Phosphogluconate dehydrogenase activity in vaginal fluid.
A NEW TEST FOR THE DIAGNOSIS OF GYNAECOLOGICAL CANCER, 6-PHOSPHOGLUCONATE DEHYDROGENASE ACTIVITY IN VAGINAL FLUID.
Activities of enzymes of the hexose monophosphate pathway in nervous system tumors induced by ethylnitrosourea.
Biochemical tissue markers of human colorectal carcinoma.
Crystal structure of Saccharomyces cerevisiae 6-phosphogluconate dehydrogenase Gnd1.
Detection of preinvasive and early invasive cancer by 6-phosphogluconate dehydrogenase determinations.
Enhanced susceptibility to a chemical carcinogen in rats carrying MHC-linked genes influencing development (GRC).
Evidence for dimer/tetramer equilibrium in Trypanosoma brucei 6-phosphogluconate dehydrogenase.
Fine-needle aspiration of thyroid nodules: proteomic analysis to identify cancer biomarkers.
Glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase activities in normal canine mammary gland and in mammary tumours and their correlation with oestrogen receptors.
Glutathione levels and sensitivity to apoptosis are regulated by changes in transaldolase expression.
Glycolytic cancer cells lacking 6-phosphogluconate dehydrogenase metabolize glucose to induce senescence.
Increased activity of 6-phosphogluconate dehydrogenase and glucose-6-phosphate dehydrogenase in purified cell suspensions and single cells from the uterine cervix in cervical intraepithelial neoplasia.
Influence of insulin on estrogen-induced responses in the r3230ac mammary carcinoma.
Inhibition of 6-phosphogluconate dehydrogenase by glucose 1,6-diphosphate in human normal and malignant colon extracts.
Lysine acetylation activates 6-phosphogluconate dehydrogenase to promote tumor growth.
Potential antitumour and pro-oxidative effects of (E)-methyl 2-(7-chloroquinolin-4-ylthio)-3-(4-hydroxyphenyl) acrylate (QNACR).
The value of 6-phosphogluconate dehydrogenase (6-PGDH) activity as a marker of tumour cellularity and prognostic indicator in primary breast cancer.
Trial of a simplified vaginal fluid 6-phosphogluconic dehydrogenase assay method in screening for cancer.
Uridine and cytidine nucleotide synthesis in renal hypertrophy: biochemical differences in response to the growth stimulus of diabetes and unilateral nephrectomy.
Vaginal fluid 6-phosphogluconic dehydrogenase activity in relation to uterine malignancy.
[Activities of dehydrogenases of the pentose phosphate pathway and transketolase in transplanted mouse hepatomas with different growth rates and in organs of tumor carriers]
[Hexokinase activity of erythrocytes in cancer patients]
Neurilemmoma
Characterization of rat schwannoma-Schwann cell hybrids.
Neuromuscular Diseases
Elevated activity of several antioxidant enzymes in neuromuscular diseases. A histochemical and biochemical study.
Obesity
Dietary soy protein induces hepatic lipogenic enzyme gene expression while suppressing hepatosteatosis in obese female Zucker rats bearing DMBA-initiated mammary tumors.
phosphogluconate 2-dehydrogenase deficiency
6-Phosphogluconate dehydrogenase deficiency in an Italian family.
A NEW INHERITED ENZYMATIC DEFICIENCY OF HUMAN ERYTHROCYTES: 6-PHOSPHOGLUCONATE DEHYDROGENASE DEFICIENCY.
Erythrocytic glutathione reductase, glucose-6-phosphate dehydrogenase, and 6-phosphogluconic dehydrogenase deficiencies in populations of the United States, South Vietnam, Iran, and Ethiopia.
Primary Myelofibrosis
Blood leucocyte enzymes. II. Activities at 8-9 a.m. in cells of normal subjects, chronic lymphatic leukaemia and chronic myeloid leukaemia patients.
Psoriasis
[Evaluation of the activities of several erythrocyte enzymes (G6PDH, 6PGDH, PHI, aldolase and LDH) in psoriasis]
Starvation
Dietary induction of hepatic glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, and malic enzyme in lean and obese female Zucker rats.
Expression of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase isoform genes in suspension-cultured Arabidopsis thaliana cells.
Pentose phosphate pathway mutants of yeast.
[Intensity of pentose phosphate metabolism of carbohydrates in various brain areas in normal and starved animals]
Stomach Ulcer
[Characteristics of the pentose phosphate pathway of carbohydrate metabolism in the gastric mucosa of persons with peptic ulcer]
Teratoma
Diverse origins of multiple ovarian teratomas in a single individual.
Trypanosomiasis, African
Aryl phosphoramidates of 5-phospho erythronohydroxamic acid, a new class of potent trypanocidal compounds.
Evidence for dimer/tetramer equilibrium in Trypanosoma brucei 6-phosphogluconate dehydrogenase.
Synthesis and Biological Evaluation of Phosphate Prodrugs of 4-Phospho-D -erythronohydroxamic Acid, an Inhibitor of 6-Phosphogluconate Dehydrogenase.
Synthesis and biological evaluation of substrate-based inhibitors of 6-phosphogluconate dehydrogenase as potential drugs against African trypanosomiasis.
The 6-phosphogluconate dehydrogenase from Trypanosoma cruzi: the absence of two inter-subunit salt bridges as a reason for enzyme instability.
Thermodynamic characterization of substrate and inhibitor binding to Trypanosoma brucei 6-phosphogluconate dehydrogenase.
Virtual fragment screening for novel inhibitors of 6-phosphogluconate dehydrogenase.
Tuberous Sclerosis
Serum and tissue proteins in tuberous sclerosis. I. Serum and red-cell polymorphic systems.
Uterine Cervical Neoplasms
6-PHOSPHOGLUCONATE DEHYDROGENASE ESTIMATION IN VAGINAL FLUID IN THE DIAGNOSIS OF CERVICAL CANCER.
Uterine Neoplasms
6-PHOSPHOGLUCONATE DEHYDROGENASE IN UTERINE CANCER DETECTION.
Isoenzymes of hexokinase, 6-phosphogluconate dehydrogenase, phosphoglucomutase and lactate dehydrogenase in uterine cancer.
The alleged usefulness of 6-phosphogluconate dehydrogenase determinations in screening for uterine cancer.
Vitiligo
Distribution of serum proteins, red cell enzymes and haemoglobins in vitiligo.
Yersinia pseudotuberculosis Infections
GLUCOSE-6-PHOSPHATE DEHYDROGENASE AND 6-PHOSPHOGLUCONATE DEHYDROGENASE ACTIVITIES OF PASTEURELLA PESTIS AND PASTEURELLA PSEUDOTUBERCULOSIS.