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1.1.1.43: phosphogluconate 2-dehydrogenase

This is an abbreviated version!
For detailed information about phosphogluconate 2-dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.43

Reaction

6-phospho-D-gluconate
+
NAD(P)+
=
6-phospho-2-dehydro-D-gluconate
+
NAD(P)H
+
H+

Synonyms

2-keto-6-phosphogluconate reductase, 6-PGADHase, 6-PGDase, 6-PGDH, 6-phosphogluconate dehydrogenase, 6-phosphogluconate dehydrogenase (NAD), 6-phosphogluconate-dehydrogenase, 6-phosphogluconic dehydrogenase, 6-phosphoglucuronic acid dehydrogenase, 6PGAD, 6PGD, 6PGDH, gluconate 6-phosphate dehydrogenase, phosphogluconate dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.43 phosphogluconate 2-dehydrogenase

Activating Compound

Activating Compound on EC 1.1.1.43 - phosphogluconate 2-dehydrogenase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
D-glucose 6-phosphate
-
-
phosphoenolpyruvate
-
-
additional information
-
nicotine activates the muscle, lungs, and testicular 6PGD enzyme activity but has no effect on heart and liver 6PGD activity, when nicotine is administered with vitamin E the increase in 6PGD enzyme activity in muscle and testicles are lower, vitamin E may favourably increase 6PGD enzyme activity in liver in nicotine treated rats, while it has negligible effects on this enzyme activity in other tissues
-